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Query: [R] KOG4198 RNA-binding Ran Zn-finger protein and related proteins, from COG1018

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MSKLPSPTMPLPESVGDLVVLHFETNLDDHGISIGRAPCEIHEICWVILDGKTLEKQHCESCSIREDSSRHGICGSASSLTEAIFTLDNSIQERLNFQGKPFTFVVMNGRELRVLLPKEARDQGITLPSYMRHPRLFDLSSEYAKWQIRMGAVPPYTITLSHIFGKLDVDSLPPITESKAIELSPSDAPYITKGLTQCWRLANATTLLLRKAEKDSRGHSLPSVLTQPINCQADARSFYAERSKIVHVAGLTNDVTQLELESWFTNHGVHPVALWTLKTPEPYKSTGTGFVLFASHEDAADALAFNGYCLGDRMLEIIPSSTKVLDKASDILIPFPSSKNRPRPGDWNCPMCGFSNFQRRTSCFRCSFPGPTHVSAATGSNTFSPDFPYGNSYGNGSSHFIANYGGSVHHSNENTMQSDLQHQNGNNAVNHHHSSRSFGGNVPFRAGDWKCGSEGCGYHNFAKNVCCLRCGASRATAAVVADHASGPVNGSYSHNSYSHIPPVMSTSPPNHSVYPYSQLSINSVTANHGQNFGGQNGGNVSRFDDHGRFKEVSRPSVTTDQGDWLCECGFTNFRRRSNCLRCNAPHYSNMQIPASLPSDFNAYVLast
1 -152.000[R] KOG4198 RNA-binding Ran Zn-finger protein and related proteins  ali  100  1MSKLPSPTMPLPESVGDLVVLHFETNLDDHGISIGRAPCEIHEICWVILDGKTLEKQHCESCSIREDSSRHGICGSASSLTEAIFTLDNSIQERLNFQGKPFTFVVMNGRELRVLLPKEARDQGITLPSYMRHPRLFDLSSEYAKWQIRMGAVPPYTITLSHIFGKLDVDSLPPITESKAIELSPSDAPYITKGLTQCWRLANATTLLLRKAEKDSRGHSLPSVLTQPINCQADARSFYAERSKIVHVAGLTNDVTQLELESWFTNHGVHPVALWTLKTPEPYKSTGTGFVLFASHEDAADALAFNGYCLGDRMLEIIPSSTKVLDKASDILIPFPSSKNRPRPGDWNCPMCGFSNFQRRTSCFRCSFPGPTHVSAATGSNTFSPDFPYGNSYGNGSSHFIANYGGSVHHSNENTMQSDLQHQNGNNAVNHHHSSRSFGGNVPFRAGDWKCGSEGCGYHNFAKNVCCLRCGASRATAAVVADHASGPVNGSYSHNSYSHIPPVMSTSPPNHSVYPYSQLSINSVTANHGQNFGGQNGGNVSRFDDHGRFKEVSRPSVTTDQGDWLCECGFTNFRRRSNCLRCNAPHYSNMQIPASLPSDFNAYV 604
2 -43.400[L] KOG0542 Predicted exonuclease  ali follow..  15  44SLKKDTKNQKMSQHFDYLLVLDFEATCQDNWKGPMHPVQEIIEFPVVQLSTADWSEIRRFHQYVKPCPRLTSFCTSLTGIIQVLSEFDSWLKEDSRLEKGKFAFVTCGDWDLKVALPNEAKFKNIGIPEYFNQW--INVKKASAEHTNHFAKGIAQLLAIYKLQHQGRHHSGIDDVANICEIVRCLGMNGHNYQITGSKDTMT................................................................................................................................................................................................................................................................................................................................................................................................................. 257
3 -38.500[R] COG5018 Inhibitor of the KinA pathway to sporulation, predicted exonuclease  ali follow..  9  29RIALQELGLSTNGNKRYLLIVDVEATCEEGCGF--SFENEIIELPCLLFDLIEKSIIDEFHSYVRPNPTLSDYCKSLTGIQQVLEELFIFLRKHSNIQPKNWAWACDGPWDMASFLAKQFKYDKMPIPDWIKG-PFVDIRSFYKDVYRVPRTNINGMLEHWGLQFEGSEHRGIDDARNLSRIVKKMCSENVEFECNRWWMEYEKNGWIPNRSYPPYFAS................................................................................................................................................................................................................................................................................................................................................................................................. 277
4 -27.700[T] KOG4345 NF-kappa B regulator AP20/Cezanne  ali follow..  10  2.................................................................................................................................................................................................................................................................................................................................................CDTKDDAQKWKCETCTYENYPSSLKCTMCQASKPLLNEDIFRLSPAQESCTVAE--------------------EAAAVEVAVMSPTPSSTCYSLQPQSQARQSNVADSEKWPCKV--CTYLNWPRSLRCVQCCTKRGGEAIERGKKDMDNEADGDRAGEALQALRISGSEENLANKPVQLIGATASHRLSLSQQMQLQLQPQQQRESSSSAAVPPQQQKQCYVSKWACNCTYENWPRSIKCSMCGKTREREISGSQNDLHASSS.. 275
5 -24.600[R] KOG0154 RNA-binding protein RBM5 and related proteins, contain G-patch and RRM domains  ali follow..  17  196.......................................................................................................................................................................................................................DRNSRRDDRRSNLSNNDRYSDWNPGVPSNKLAILNMPNDVDNTKITLSLGKCGYLPQDVRTKFDKNTKQIRTFAFVEFSNRETAEQWMTDYEGWLDGRTLAVEYAKGD------------PAAGSGNKGDDWICAHCSMNNFVKRQTCFKCEISKDQSMELEKLGAHMVGMTPCD...................................................................................................................................................................................................................... 363
6 -23.100[AR] KOG1365 RNA-binding protein Fusilli, contains RRM domain  ali follow..  10  1.................................MITSEQRLLLIRVSDGNYDENTKLVVTSFYPRRQEDANNNSTSPSSASSSGSEIPEDVVKFFDEHPTSSYIFTKGPEPIRHVLIPLFARNELCVPHPLHHYYDIKHLYY-------------------------------------------GNQEEDGMEQEEIEDDVAIARAILDMDDELLEKTHQFNIEYQPAPILEDQEVGADGDNVVCRARGLPWQASDHHVAQFFAGLDIVPGGIALCLSS-EGRRNGEVLVQFSSQESRDLALKRHRNFLLSRYIEVYKAGLDEFMHVATGSSTEAMEFVSANAIPYDCTDAQIRTF....................................................................................................................................................................................................................................................... 296
7 -19.400[R] KOG1995 Conserved Zn-finger protein  ali follow..  12  276...............................................................................................................................................................................................................................................NCDNARIYISNLPPDVTTDELKDLFGGIGQVGRI---IYTDEKGNYKGDACLAYEDPSAAHSAGGFNNYEMRGNKISVTMAEKSAPRAPTFDQSFIILVGNMSGMTERMSVSDLIMLSLQTCECRRGGGRGGGGGG-------------------------------------------------GGGGGDRRRDNYSSGPDRNHHGGNFNC-KMHCK................................................................................................................................................... 490
8 -18.700[A] KOG4209 Splicing factor RNPS1, SR protein superfamily  ali follow..  19  60.................................................................................................................................................................................................................................SNSSQSLLTPEEKAEADAKSVYVGNVDYGATAEEIEQHFHGCG-SVSRVTIQCDRFSGHPKGFAYVEFTEKEGMQNALAMTDSLLRGRQIKVDPKRTNKPGMSTTNRPPFRGRGGRGRGN................................................................................................................................................................................................................................................................... 178
9 -18.500[R] KOG4307 RNA binding protein RBM12/SWAN  ali follow..  16  2..................................................................................................................................................................................................................................................SVIIRLKNLPMTAGASDVRTFFTGLKIPDGAVHII-----GGDEGEVFVGFSSDDDARLAMTKDRLMIHGAEVRLFLSSKSEQNSVIAARKNNTYTSPVYKE.................................................................................................................................................................................................................................................................... 98
10 -18.500[R] KOG0114 Predicted RNA-binding protein (RRM superfamily)  ali follow..  18  2......................................................................................................................................................................................................................................NKRNHIRLPPEVNRLLYVRNLPYKITSDEMYDIFGKFG----AIRQIRVGNTPETRGTAFVVYEDIFDAKNACDLSGFNVCNRYLVVLYYQSNKAFKRVDMDKKQEELNNIKAKYN.................................................................................................................................................................................................................................................................. 114
11 -17.800[R] KOG0149 Predicted RNA-binding protein SEB4 (RRM superfamily)  ali follow..  18  6.................................................................................................................................................................................................................................VPGSGFHYLNSPFGDTTFTKVFVGGLAWETQSETLRQHFEQYG-EILEAVVIADKNTGRSKGYGFVTFRDPEAARRACADPTPIIDGRRANCNLASLGRPRPPLPYAVIPNMPDLLPRTLE.................................................................................................................................................................................................................................................................. 125
12 -17.300[A] KOG0121 Nuclear cap-binding protein complex, subunit CBP20 (RRM superfamily)  ali follow..  18  6...........................................................................................................................................................................................................................ELSSYRDQHFKGSRSEQERSLRDSCTLYVGNLSFYTTEEQIHELFSRCG-DVRVIVMGLDKYKKTPCGFCFVEYYVRSEAEAAMRVNGTRLDDRLIRVDWDAGFVEGRQ.................................................................................................................................................................................................................................................................................... 114
13 -17.200[R] KOG0130 RNA-binding protein RBM8/Tsunagi (RRM superfamily)  ali follow..  13  46........................................................................................................................................................................................................................EAIHSYERVRNEDDDELEPGPQRSVEGWILFVTSIHEEAQEDEIQEKFCDYG-EIKNIHLNLDRRTGFSKGYALVEYETHKQALAAKELNGAEIMGQTIQVDWCFVK......................................................................................................................................................................................................................................................................................... 152
14 -17.100[A] KOG4211 Splicing factor hnRNP-F and related RNA-binding proteins  ali follow..  10  3LGTEGGEGFVV-----KVRGLPWSCS-----------ADEVQRFIRFIYTREGRPSGEAFVELESEDEVKLALKKDRETMGHRYVEVFKSNNVEMDDTANDGFVRLRG-------LPFGCSKEEIV--QFFS-FVQFASQEIAEKALKKHKERIGHRYIEIFKSSRAEVRTHYDPPRKLMAMQERMRRGAYGGGYGGYDDYNGYNDGYGFGSDRFGRDLNYCFSGMSDHRYGDGGSTFQSTTGHCVHMRGLPYRATENDIYNFFSPLNPV--RVHIEIGP-DGRVTGEADVEFATHEDAVAAMSKDKANMQHRYVELFLNSTAGASGGAYEHRYVELFLNSTAGAS.................................................................................................................................................................................................................................................................. 388
15 -16.800[A] KOG4207 Predicted splicing factor, SR protein superfamily  ali follow..  21  10...............................................................................................................................................................................................................................................VDGMITLKVDNLTYRTSPDSLRRVFEKYG-RVGDVYIPLEPHTKAPRGFAFVRFHDRSDAQDAEAMDGAVLDERELRVRMARYGRRDLPRSSQEEPRGRSWGGRYGR.................................................................................................................................................................................................................................................................. 116
16 -16.800[J] KOG0899 Mitochondrial/chloroplast ribosomal protein S19  ali follow..  18  50......................................................................................................................................................................................................................................PVSSMLGSLRYMSTKLYIGGLSPGTDEHSLKDAFSSFN-GVTEARVMTNKVTGRSRGYGFVNFISEDSANSAISMNGQELNGFNISVNVAKDW......................................................................................................................................................................................................................................................................................... 142
17 -16.300[R] KOG0125 Ataxin 2-binding protein (RRM superfamily)  ali follow..  20  86.........................................................................................................................................................................................................................TEGGAQTDGQQSQTQSSENSESKSTPKRLHVSNIPFRFRDPDLRQMFGQFG-KILDVEIIFN--ERGSKGFGFVTFENSADADRARELHGTVVEGRKIEVNNATARVMTNKK................................................................................................................................................................................................................................................................................... 195
18 -16.200[A] KOG0108 mRNA cleavage and polyadenylation factor I complex, subunit RNA15  ali follow..  22  1.............................................................................................................................................................................................................................................MSMTAGNVVFVGNIPYDVSEQQMTEIFNQVG-PVKTFKLVLDPETGSGKGYGFCEFFDSETTAMAVRLNNSELGPRKIRVEFPSNDPRRNQSY.................................................................................................................................................................................................................................................................................. 93
19 -15.500[R] KOG4208 Nucleolar RNA-binding protein NIFK  ali follow..  19  1.............................................................................................................................................................................................................................................MAAFSRSAGPILSLNP-QEDAELQKEVAQCD-TVTRFRLSRKKRTGNSKGYAFVEFESEDVAKIVTTMNSYLFGERLLECHFMPPEKKME..................................................................................................................................................................................................................................................................................... 89
20 -15.300[L] KOG4793 Three prime repair exonuclease  ali follow..  11  1MGSQALPPGPMQT----LIFFDMEAT-------LPFSQPKVTELCLLAVHRCALRVVDKLSLCVAPGKACSPAASEITGLSTAVDNLANLLLAFLRRQPQPWCLVAHNRYDFP-LLQAELAMLGLTSADSITALKALERASSPSEHGPRKSYSLGSIYTRLYGQSPPDSHTAEGDVLALLSICQWRPQALLRWVDAHARPFGTIRPMYGVTASARTKPRPSAVTTTAHLATTRNTSPSLGESRGT-LGLLAILTLAVATLYGLSLA.................................................................................................................................................................................................................................................................................................................................................. 310
21 -15.300[R] KOG0226 RNA-binding proteins  ali follow..  22  199...............................................................................................................................................................................................................................................DENDFRVFCGDLGNEVSDELLAKAFRKYP---QKAKVVRESRTNKSKGYGFVSFRDSEDYVRAMEMDGKYVGNRPIKLRKSAWKERNIDVIKQKRKQKKE......................................................................................................................................................................................................................................................................... 298
22 -15.200[J] KOG0122 Translation initiation factor 3, subunit g (eIF-3g)  ali follow..  22  186........................................................................................................................................................................................................................AAYVPPSMRAGADRSAVGSDMRRRNDENSVRVTNLSEDTREPDLMELFHPFG-AVTRVYVAIDQKTGVSRGFGFVNFVSREDAQRAINLNGYGYDNLILRVEWATPR......................................................................................................................................................................................................................................................................................... 292
23 -15.000[R] COG0724 RNA-binding proteins (RRM domain)  ali follow..  20  187...............................................................................................................................................................................................................................................RDDMCTLKIMQVNENADENSLRELLFPFA-PIPRVSVVRNKETGKSRGLAFVTFSSEEVAEQALRLDGRGYMNLILRVEWSKPKVKE...................................................................................................................................................................................................................................................................................... 274
24 -14.500[L] COG0847 DNA polymerase III, epsilon subunit and related 3`-5` exonucleases  ali follow..  10  12.................IVVLDTETTGMNREGGPHYEGHRIIEIGAVEI-INRKLTGRHFHVYLKPDRDIQLEAIEVHGITDEFLKYKDVHEEFVDFIKGAELVAHNAPFDVG-FMDYEFAKLGGAIGKTSDFCKVTDTLAMAKRIFPGKRNNLDILCERYGIDNSHRTHGALLDAEILADVYLLMTGGQTSLQFSSVTQNSGELSAESLKRAR...................................................................................................................................................................................................................................................................................................................................................................................................... 211
25 -13.800[A] KOG0107 Alternative splicing factor SRp20/9G8 (RRM superfamily)  ali follow..  26  4.....................................................................................................................................................................................................................................................VYVGNLDPRVTERELEDEFRSFG-VIRSVWVARR-----PPGYAFLDFEDSRDARDAIRVDGKNGWRVEQSHNRGGGG......................................................................................................................................................................................................................................................................................... 76
26 -13.600[A] KOG3242 Oligoribonuclease (3`  ali follow..  13  1..........MSNLKQPLVWIDCEMT-------LEVGKHVLMEVAAIITDGNLRPVEEKFDAVIKLSGLTERCRQSNLTVKDVENQLLAYIKKYIPKKREALIAGNSVHADVR-FLSVEMPKIIEHL-----HYRIIDVSTIKELAKRWCPDIPAYDKK--------GDHRALSDILESIGELQHYRS................................................................................................................................................................................................................................................................................................................................................................................................................................ 176
27 -13.600[A] KOG0124 Polypyrimidine tract-binding protein PUF60 (RRM superfamily)  ali follow..  9  1..................................................MATATIALQVNGQQGGGSEPAA--AAVVAAGDKWKPPQG-ENGQSTAAKLGLPPLTPEQQE-QQLTNLQMAAVTMGFPLSPLQSMAAQRQRALAIMCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFG-KIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSMNLFDLGGQYLRVGKAVTPPMPLLTPATPGGLPPAAAVAAAA.................................................................................................................................................................................................................................................................. 328
28 -13.400[A] KOG4205 RNA-binding protein musashi/mRNA cleavage and polyadenylation factor I complex, subunit HRP1  ali follow..  13  1MTSTGATAVATLRETSPPVEEARLNADSDDGSHGSQDPGKMF-IGGLSWQTTAENLRDYFGRF---------------EVNECMVMRDPATKR-----ARGFGFITFVD--------PSSVDKVLNNREHELDGKKIDPKVAFPK----------------------------------------------------------------------------------------RTQAKLVTKTKKVFIGGLSATSTLEDMKQYFETYG-KVEDAMLMFDKATQRHRGFGFVTFDSDEVADKVCEIHFHEINGKMVECKKAQPKEVMLPVQLNKSRAAAA......................................................................................................................................................................................................................................................................... 228
29 -13.300[R] KOG4733 FOG: RRM domain  ali follow..  18  54...........................................................................................................................................................................................................................................SGWDQLSKTNLYIRGLPPHTTDQDLVKLCQPYG-KIVSTKAILDKTTNKCKGYGFVDFDSPAAAQKAVSLKASGVQAQMAKQQEQDPTNLQELENMLKPFGQVISTRILRD-TSRGVGFARMESTEKCEAV.............................................................................................................................................................................................................................................. 197
30 -13.300[A] KOG0131 Splicing factor 3b, subunit 4  ali follow..  12  3.......................................TRIAPGVGA-GQHSAERNQDATVYVG----LDAQLSE-ELLWELFVQAGP-PKDRVTNLHQNYGFIEYRS---------------------------------------------------------------EEDADYAIKVLNMIKLHGKPIRVNKASQ-----------------------------------DKKSLDVGANLFIGNLDPDVDEKLLYDTFSAFGVIASNPKIMRDPDTGNSRGFGFISYDSFEASDAAIEMTGQYLSNRQITVSYAYKKDTKGER................................................................................................................................................................................................................................................................................... 198
31 -13.100[R] KOG4454 RNA binding protein (RRM superfamily)  ali follow..  15  5...........................................................................................................................................................................................................................................PTPSPPEERTIYVANFSEEVDEELLEELFIQAG---VKVILRDV--RDSNAKFALVEFEDELSVLFAIEMNGVRLFNQELQVKPRNGTNQEELYKRKKGEIEERVRSVAAP.................................................................................................................................................................................................................................................................. 113
32 -13.100[A] KOG0105 Alternative splicing factor ASF/SF2 (RRM superfamily)  ali follow..  22  10...............................................................................................................................................................................................................................................GEGDGRIYVGNLPTDVREKDLEDLFYKYG----RIREIELKNRHGLVPFAFVRFEDPRDAEDAIYRNGYDYGQCRLRVEFPRTYGGRGGWPRGGRNGPPTRRSD..................................................................................................................................................................................................................................................................... 110
33 -13.100[AJ] KOG0123 Polyadenylate-binding protein (RRM superfamily)  ali follow..  11  1................................................MNAAASS-YPMASLYVG----LHSDVTE-AMLYEKFSPAGP-CRDMITRRSLGYAYVNFQQPADAERALDTMNFDVIK-----------PIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFG-KTLSVKVMRDP-NGKSKGFGFVSYEKHEDANKAVEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQ---VNLYIKNFSPFGSITSAKVMLEDGRSKG................................................................................................................................................................................................................................... 334
34 -12.800[A] KOG4206 Spliceosomal protein snRNP-U1A/U2B  ali follow..  13  1..........................................................................................................................................................................................................................................MLTADIPPNQSIYIQNLNERIKKEELKRSLYCLFSQFGRILDVVALKTPKLRGQAWVTFSEVTAAGHAVRMQNFPFYDKPMRLQYAKAKSDCLAKAEGTFVPKDKKRKQEEK.................................................................................................................................................................................................................................................................. 113
35 -12.800[R] KOG0126 Predicted RNA-binding protein (RRM superfamily)  ali follow..  10  29............................................................................................................................................................................................................................................HSEYKDSAWIFLGGLPYELTEGDIICVFSQYG-EIVNINLVRDKKTGKSKGFCFLCYEDQRSTILAVNFNGIKIKGRTIRVDHVSNYRAPKDSEEIDDVTRQLQEKGCGA--------------------RTPSPSLSESSEDEKPTKKHKKDKKEKKKKKKEKEKADREVQAEQPSSSSPRRKTVKEKDDTGPKKHSSKNSERAQKSEPREGQKLPKSRTAYSGGAEDLERELKKEKPKHEHKSSSRREAREEKTRIRDRGRLQMHILAGIMGVLKGVVIEVEVGAEINPIGIKGPDAPGRGVLRIPVTVGVTEDFSCTVDLE------KCSQIQLGGYYFCI........................ 351
36 -12.700[A] KOG0128 RNA-binding protein SART3 (RRM superfamily)  ali follow..  8  326FERDRRPNEEIDALWERAR------------SNVINSAEEGRSLYRTYAFTGSSDYSPMAEVFDEGAALLREYASLMKNMDKCRNIWNDILASGFGRFAGRLERQFGDKENARKYLNKALNSVSDNINEIYMYYVQFEREEAELDLVLEKVNSQVAHRAIRPQKKVSEKPAPAPKSKQDHIQKRTSGGEPIVKKVKGDDGGFKAPLPPSNAKSSSAVSSSNASSTPAPGSFAVQKAAPGTEDARTIFVSNLDFTTTEDEIRQAIEGVA----SIRFAR-NSDLVHRGFAYVVMENDQKAQQALLKDRVPVKGRPMFISANDPEKRVGFKFSTTLEKSK-RRVTHKDGKPKGIAFVDFDTEASAQKCALSNPPVKKDKSHGKPAAIGASLEEDGPRKGHAAKLQLVPRAITNKTPQITARLDAMDVSEGTSTSQPLSNDQFRKMFMKN............................................................................................................................................................. 836
37 -12.600[D] KOG2186 Cell growth-regulating nucleolar protein  ali follow..  19  400...........................................................................................................................................................................................................................................SADRDIAQRNIFVRGFGWDTTQENLKTAFESYG-EIEECSVVMDKDTGRGKGYGFVMFKTRKGAREALKRPEKRMYNRIVVCNLASEKPGKAGKEQDMAEPVN.......................................................................................................................................................................................................................................................................... 501
38 -12.600[A] KOG0146 RNA-binding protein ETR-3 (RRM superfamily)  ali follow..  13  4.................................................................................................................................................................................................KMATLANGQADNASLSTNGLGSSPGSAGHMNGLSHSPGNPSTIPMKDHDAIKLFIGQIPRNLDEKDLKPLFEEFG-KIYELTVLKDRFTGMHKGCAFLTYCERESALKAQSLHEQKTLPRPIQVKPADSESRGGSSCLRQPPSQDRK-LRGPDGNSKGCAFVKYSSHAEAQAA.............................................................................................................................................................................................................................................. 208
39 -12.200[K] KOG0147 Transcriptional coactivator CAPER (RRM superfamily)  ali follow..  14  133..................................................................................................................................................................................................................................SPVREPVDNLSPEERDARTVFCMQLAARIRPRDLEDFFSAVG-KVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIGLTGQRLLGVPIIVQASQAEKNRLAAMANNLQKGNGGPMR--HFNITEDMLRGFEPFGKIDNIVLMKDSDTGRSKG................................................................................................................................................................................................................................. 289
40 -12.200[A] KOG0117 Heterogeneous nuclear ribonucleoprotein R (RRM superfamily)  ali follow..  10  1MESNHKSG---------DGLSGTQKEAAL--------RALVQRTGYSLVQENGQRKERGCEIFIGPRDLFED------ELIPLCEKIGK-MMMDFNGNNRGYAFVTFSNKVEAKNAIKQLNNYEIRNGRLLGVCASVDNCRLFVG-------GIPKTKKREEILSEMKK--TEGVVDVIVYPSAADKTKNRGFAFVEYESHRAAAMARRKLLPGRIQLWGHGIAVDWA-EPEVEVDEDTMSSVKILYVRNLMLSTSEEMIEKEFNNIK--------GAVERVKKIRDYAFVHFSNREDAVEAMKLNGKVLDGSPIEVTLAKPVDKDSYVRYTRGTGGRGTMLQ..................................................................................................................................................................................................................................................................... 324
41 -12.200[A] KOG0145 RNA-binding protein ELAV/HU (RRM superfamily)  ali follow..  15  36.....QTGATTDDSKTNLIVNYLPQNMTQEERSLFGSIGEIESC--LVRDKITGQSLG----FVN---------IDPKDAEKAINTLNSYARPSSASIRDANLYVTMTQKELEQLFSQYGRIITSRI-GFIRFDKRIEAEEAIKGLNGQKPSGATEPITVKFANNPSQKSSQALLSQLYQSPNRRHQAQRFRLDNLLNMAYGVKRLMSGPVPPSACSPRFSPITIDGMTSLVGMNIPGHTGTGWCIFVYNLSPDSDESVLWQLFGPFG-AVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIALNGYRLGDRVLQVSFKTNKAHKS..................................................................................................................................................................................................................................................................................... 380
42 -12.100[R] KOG0118 FOG: RRM domain  ali follow..  19  155.................................................................................................................................................................................................................................KRRMNARTSMAQREDVIRRTVYVSDLDQQVTEEQLAGLFVSCG-QVVDCRICGD--PNSVLRFAFIEFTDEEGAMTALNLSGTMLGFYPVKVLPSKTAIAPVNPTFLPRTEDEREMCARTIY------CTNIDKKVT.................................................................................................................................................................................................................................................. 282
43 -12.000[A] KOG0533 RRM motif-containing protein  ali follow..  20  70...............................................................................................................................................................................................................................................DSKVIRVNISNLAPTVISSDLEELFGDYRLSSVSV-----NEHGDSLGTGDISLTKRDAERLVQKFSGVALDGKIMKF............................................................................................................................................................................................................................................................................................... 144
44 -12.000[A] KOG0144 RNA-binding protein CUGBP1/BRUNO (RRM superfamily)  ali follow..  18  389...........................................................................................................................................................................................................................................SQKEGPEGANLFIYHLPQEFGDQDLLQMFMPFG-NVVSAKVFIDKQTNLSKCFGFVSYDNPVSAQAAIQMNGFQIGMKRLKVQLKRSKNDSK..................................................................................................................................................................................................................................................................................... 480
45 -11.600[A] KOG0106 Alternative splicing factor SRp55/B52/SRp75 (RRM superfamily)  ali follow..  25  4.....................................................................................................................................................................................................................................................VYIGRLPNRASDRDVEHFFRGYGLSDVIM----------KNGFGFVDFQDQRDADDAVDLNGKELCGERVILEFPRRKVGYNEERSGSGFRGREPTFRKGG.................................................................................................................................................................................................................................................................. 96
46 -11.400[A] KOG4212 RNA-binding protein hnRNP-M  ali follow..  23  635.................................................................................................................................................................................................................................AGSFGGAGGHAPGVARKACQIFVRNLPFDFTWKMLKDKFNECG-HVLYADIKME--NGKSKGCGVVKFESPEVAERACRMNGMKLSGREIDVRIDRNA......................................................................................................................................................................................................................................................................................... 730
47 -11.400[A] COG1949 Oligoribonuclease (3`  ali follow..  10  14YSHCEWVENSMSANENNLIWIDLEMT-------LDPERDRIIEIATLVTDANLNILAEGPTIAVHQSGLVERVKASTMGDREAELATLEFLKQWV--PAGKSPICGNSGQDRR-FLFKYMPELEAYF-----HYRYLDVSTLKELARRWKPEILDGFTKQ-------GTHQAMDDIRESVAELAYYRE................................................................................................................................................................................................................................................................................................................................................................................................................................ 199
48 -11.300[R] KOG0110 RNA-binding protein (RRM superfamily)  ali follow..  10  504....................LDTSDGGSSAAVRLALGETQVVIEMKRFLEEEGVRLRSNTVILAK------PAATEISEITPIFSRFGP-IGRIVLPPSGVTALIEYCD-------PLEARQKKLAYSKFKNAPLYLEWAPEQVFTKTLSGENLNFKTVQETVEKHFRHLGSIHTVEIAKRRDPENPREFKSLGYVAEHALKNLQLTHIDGNPVELKRSDRVLKTQDNDGAQRRLASQKKQTGTKILVRNIPFQAQYREVRDIFKAFGLRSLRIPKKATTGEDAHRGFGFVDYMSKAEAKRAFDAASTHLYGRRLVLEWSANDDNQDVEELRKRTAA........................................................................................................................................................................................................................................................................... 881
49 -11.300[A] KOG0115 RNA-binding protein p54nrb (RRM superfamily)  ali follow..  13  106.................................................EVPKKKFTGRCRLFVG----LPNEVKE-TELKELFSPHGDIAECYLSGKG--FAFLRLDT--------RAHAESAK-------------------------------------------------------------------------------------------------EAIDGRIIHGRQVRVRFAVHGAAIRVKELSPTVSNEMLYHAFSHFG-DVERAVHIVDE-KGRPTGEGIVEFERKPNCNEAMAIRDKVFSPKPLICEVLEPRDEDDGLA.................................................................................................................................................................................................................................................................................. 278
50 -11.300[K] KOG4210 Nuclear localization sequence binding protein  ali follow..  15  215...........................................................................................................................................................................................................................KDSENYSGRPDKDDLVAMSKNPPSRILFVGNLSFDVTDDLLRKHFQHCG-DIVKIRMATFEDSGKCKGFAFIDFKNEEGSTNELKKSCRKIAGRPLRMEYGEDRSKRQVRKKVENVSRNNSSSF..................................................................................................................................................................................................................................................................... 338
51 -10.600[T] KOG0116 RasGAP SH3 binding protein rasputin, contains NTF2 and RRM domains  ali follow..  13  1MALESNAPVVDPNTIKYYNLLY-------------KSPSQVHQF-------------LDDSVLGRPGS-EMVSVKSLKAINEQIMSFDLTADSQASYMNGVVTLVT-GLLTVKEGQRMRFSQSFFLVPLNGSYFVLNDVQPEAKQTTENTVKKPERAVANGHPKTQEDNVVNDKSNGVDAPKKSFAHIVQDLAQNGATFNAKASPAKPKSKPVTKPSAARESKAPAPVSEHSSAATIDQQAEGYTIFVANLLMDATPEQLNETFKGFG---TKDGIQVRSYRLKGNCFGFVTFASAEAVKLVLQAHKESIGNRRVSIEEKRGN......................................................................................................................................................................................................................................................................................... 358
52 -10.400[J] KOG0129 Predicted RNA-binding protein (RRM superfamily)  ali follow..  11  445............................QNGERVERYSRKVF-VGGLPPDIDEDEITASFRRF---------------PLIVDWPHKA---ESKSYFPPKGYAFLLFQD-SVQALIDACIEEDG-----------------------------------------------------------------KLYLCVSSPTIKDKPVQIRPWNLSDSDFVMDGSQPL---------------DPRKTIFVGGVPRPLRAVELAMIMDRLYGGVCYAGIDTDPELKYPKGAGRVAFSNQQSYIAAISARFVQLQHGEIDKRVEVKPYVLDDQL--DECQGARCGGKFAPFFCANVTCLQY-----CEYC.............................................................................................................................................................................................................................................. 680
53 -10.400[R] KOG1457 RNA binding protein (contains RRM repeats)  ali follow..  16  66........................................................................................................................................................................................................................HHHTYPNLLQDTVSVLFVHELKTRPGVRTLFVSGLPVDIKPRELYLLFRPFGYEGSLIKL------TARQPVGFVIFDSRAGAEAAKNLNGIRFDPENPQTLRLEFAKANTKMAKSKLMATPNPS....................................................................................................................................................................................................................................................................... 186
54 -10.200[A] KOG0120 Splicing factor U2AF, large subunit (RRM superfamily)  ali follow..  10  84..................................................VGSTITRQARRLYVGTEEEMMEFFNQQMHLVGLAQAAGSPVLACQINLDKNFAFLEFRS--------IDETTQAMAF--------------------------------------------------------------------DGINLKGQSLKIRRPHDYQPMPGITDTPAIKPAVVSSGVISTVVPDSPHKIFIGGLPNYLNDDQVKELLLSFG---RAFNLVKDAATGLSKGYAFCEYVDLSITDQSIALNGMQLGDKKLIVQRASVGAKNAQNAANTTQSVM.......................................................................................................................................................................................................................................................................... 301
55 -10.200[K] KOG1548 Transcription elongation factor TAT-SF1  ali follow..  16  80.....................................................................................................................................................................................................................STSAEGYPSGSRNKKSKSENSEASPAPVINKAVYIQGLPLDVTVDEIEEVFKKCGNGTPRIKIYRT-EDGTPKGDALIVFFRSESVELAEQFDDTEFRYGSGQKMRVQKANIDYKKEKTVNKDVGGALKK..................................................................................................................................................................................................................................................................... 216
56 -9.830[R] KOG0153 Predicted RNA-binding protein (RRM superfamily)  ali follow..  11  1MSKTNTYNRQNWEDAEFPILCQ---TC------LGDNP----------VRMIKERFGKECKICTRPFTIFTEICQTCARLKNV-----------------QTCLL-----DLEYGLPIQVRDAALKVADYYIQNIDAQLQDGDGTEAAGAVGRSLAANEMLSKLARTAPYYKRNRPHICSFWVKGECKRGEECPYRHDKPNEPDDPLCEQNIKDRYYGRNDPEKIMKRAASLPTLEPPEDRNITTLYVGNLPEEITEPELRDQFYQFG----EIRSIA-----PRQQCAFVQYTKRNAAELAAEFNKLVIQGRKVSIKWAHSQAKQGTAA.................................................................................................................................................................................................................................................................................. 311
57 -9.380[YU] KOG2834 Nuclear pore complex, rNpl4 component (sc Npl4)  ali follow..  10  270VAAIYEP--PQIGTQNSLELLE-AEVVDEIAAKLG-----LRKVGWIFTDLVSEDTRKGTVRYSRNKDTYFLSSEECITAGDFQNKHPNMCRLSPDGHFGS-KFVT--------AVATGGPDNQVHFEGYQVSNQCMALVRD----------------ECLLPCKDAPELGYAKESSSEQYVPDVFYKDVDKFGNEITQLARPLVEYLIIDITTTFPKDPVYTFSISQNPFPIENRDVLGETQDFHSLATYLSQNTSSVFLDTISDFHL----LFLVTNEVMPLQDSISLLLEAVRTRNEELAQTWKRSEQWATIEQLCSTVGGQLPGLHEYGAVEGSTHTATAAMWACQHCTFMNQPGTGHCEMCSLPRT......................................................................................................................................................................................................................................... 608
58 -9.330[A] KOG4849 mRNA cleavage factor I subunit/CPSF subunit  ali follow..  11  65.......................................................................................................................................................................................................................EPGERNSGGPNGVYHQSSGSLTPTMNRRYQLYVGNLTWWTTDQDIANSLRDIGVSDQEVKFFENRANGQSKGFSVISLGSESSLRAVLDLPKKEMHGQAPVVTYPSKQALTQFESLQKTRPVPPPQQNGPP.................................................................................................................................................................................................................................................................. 197
59 -9.110[AJ] KOG0148 Apoptosis-promoting RNA-binding protein TIA-1/TIAR (RRM superfamily)  ali follow..  19  82......................................................................................................................................................................................................................................TTPSSQKKDTSNHFHVFVGDLSPQITTEDIKAAFAPFG-RISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQMGGQWLGGRQIRTNWATRKPPAPKSTYESNTKQLSYDEVVNQ.................................................................................................................................................................................................................................................................. 197
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Ye Y, Godzik A. Multiple flexible structure alignment using partial order graphs. Bioinformatics. 2005 Mar 3;