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Query: [A] KOG4206 Spliceosomal protein snRNP-U1A/U2B, from COG1018

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MLTADIPPNQSIYIQNLNERIKKEELKRSLYCLFSQFGRILDVVALKTPKLRGQAWVTFSEVTAAGHAVRQMQNFPFYDKPMRLQYAKAKSDCLAKAEGTFVPKDKKRKQEEKVERKREDSQRPNTANGPSANGPSANNGVPAPSFQPSGQETMPPNNILFIQNLPHETTSMMLQLLFEQYPGFKEIRMIDAKPGIAFVEYEDDVQASIAMQPLQGFKITPQNPMVISFAKKLast
1 -102.000[A] KOG4206 Spliceosomal protein snRNP-U1A/U2B  ali  100  1MLTADIPPNQSIYIQNLNERIKKEELKRSLYCLFSQFGRILDVVALKTPKLRGQAWVTFSEVTAAGHAVRQMQNFPFYDKPMRLQYAKAKSDCLAKAEGTFVPKDKKRKQEEKVERKREDSQRPNTANGPSANGPSANNGVPAPSFQPSGQETMPPNNILFIQNLPHETTSMMLQLLFEQYPGFKEIRMIDAKPGIAFVEYEDDVQASIAMQPLQGFKITPQNPMVISFAKK 232
2 -55.500[A] KOG0105 Alternative splicing factor ASF/SF2 (RRM superfamily)  ali follow..  18  6.DERGGEGDGRIYVGNLPTDVREKDLED----LFYKYGRIREIELKNRHGLVPFAFVRFEDPRDAEDAIYGRNGYDYGQCRLRVEFPRTYGGRGGWPRGG-----------------------------------------------RNGPPTRRSDFRVLVSGLPPSGSWQDLKDHMREAGDVCYADV--QKDGVGMVEYLRKEDMEYALRKLDDTKFRSH-EGETSYIRV 182
3 -54.700[A] KOG1190 Polypyrimidine tract-binding protein  ali follow..  18  349.GLAGAGNSVLLVSNLNPERVTPQSL----FILFGVYGDVQRVKILFNK--KENALVQMADGNQAQLAMSHLNGHKLHGKPIRITLSKHQNVQLPREGQE--------------------------DQGLTKDYGNSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSVSEEDLKVLFSSNGGVVKGFKFQKDRKMALIQMGSVEEAVQALIDLHNHDLGENHHLRVSFSKS 548
4 -51.700[AJ] KOG0148 Apoptosis-promoting RNA-binding protein TIA-1/TIAR (RRM superfamily)  ali follow..  16  2....EDEMPKTLYVGNLSRDVTEALILQ----LFSQIGPCKNCKMIMTAGNDPYCFVEFHEHRHAAAALAAMNGRKIMGKEVKVNWATTPSSQKKDTSNNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAPKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPD-KGYSFVRFNSHESAAHAIVSVNGTTIEGH-VVKCYWGKE 275
5 -50.700[A] KOG4212 RNA-binding protein hnRNP-M  ali follow..  17  63.PYANPTKRYRAFITNIPFDVKWQSLKDLVK---EKVGEVTYVELLMEGKSRGCAVVEFKMEESMKKAAEVLNKHSLSGRPLKVKEDPDGEHARRAMQ--------------KVMATTGGMGMGPGGPGMITIPPSILNNPNIPNEIIHALQAGRLGSTVFVANLDYKVGWKKLKEVFSMAGVVVRADILEDSRGIGTVTFEQSIEAVQAISMFNGQLLFDR-PMHVKMDER 281
6 -49.200[A] KOG0120 Splicing factor U2AF, large subunit (RRM superfamily)  ali follow..  11  84VGSTITRQARRLYVGNIPFGVTEEEMME----FFNQQMHLVGLAQAAGNLDKNFAFLEFRSIDETTQAM-AFDGINLKGQSLKIRRPHDYQPMPGITDTP-------------------------------------AIKPAVVSSGVISTVVPDSPHKIFIGGLPNYLNDDQVKELLLSFGKLRAFNLVKDSKGYAFCEYVDLSITDQSIAGLNGMQLGDK-KLIVQRASV 285
7 -48.700[A] KOG0145 RNA-binding protein ELAV/HU (RRM superfamily)  ali follow..  16  124.PSSASIRDANLYVSGLPKTMTQKELEQ----LFSQYGRIITSRILVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITVKFANNPSQKSSQALLSQLYQSPNRRNMAYGVKRLMSGPVPPSACSPRFSPITIDGMTSLVGMNIPGHTGTGWCIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDCKGFGFVTMTNYDEAAMAIASLNGYRLGDR-VLQVSFKTN 375
8 -47.600[R] KOG0110 RNA-binding protein (RRM superfamily)  ali follow..  17  357..EDDISESGRIFFRNLAYTTTEEDLRK----LFEQFGPVVEVNLPLTRKIKGFGTVTYMMPEHALKAFNTLDGTDFHGRLLHLLPSKDIEKNPKEDLDENDASLSFKEKKALDGGSSAAVRLALGETQVVIEMKRFLEEEGVRLDAFDEPAKKRSNTVILAKNLPAATEISEITPIFSRFGPIGRIVL-PPSGVTALIEYCDPLEARQAFKKLAYSKFKNA-PLYLEWAPE 624
9 -46.800[A] KOG0124 Polypyrimidine tract-binding protein PUF60 (RRM superfamily)  ali follow..  15  122..QRALAIMCRVYVGSIYYELGEDTIRQ----AFAPFGPIKSIDMSWTMKHKGFAFVEYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNIGQAQPIID--------------------------------------------------QLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQ-YLRVGKAVT 304
10 -46.600[R] KOG0118 FOG: RRM domain  ali follow..  16  165.AQREDVIRRTVYVSDLDQQVTEEQLAG----LFVSCGQVVDCRICGDNSVLRFAFIEFTDEEGAMTALN-LSGTMLGFYPVKVLPSKTAIAPVNPTFLPRTEDEREM-----------------------------------------------CARTIYCTNIDKKVTQSDVKIFFESFCGEVYRLRLQHSTRIAFVEFVMAESAIAALN-CSGVVLGSL-PIRVSPSKT 346
11 -46.100[A] KOG0128 RNA-binding protein SART3 (RRM superfamily)  ali follow..  16  585.AAPGTEDARTIFVSNLDFTTTEDEIRQ----AIEGVASIRFARKANSLVHRGFAYVVMENDQKAQQALL-KDRVPVKGRPMFISANDPEKRVGFKFSTT------------------------------------------------------LEKSKVFVRNVHFQATDDELKALFSKFGTVTSVRRVTKPKGIAFVDFDTEASAQKCVASGDKLMLRER-ELEVALSNP 760
12 -44.900[AJ] KOG0123 Polyadenylate-binding protein (RRM superfamily)  ali follow..  18  3.AAASSYPMASLYVGDLHSDVTEAMLYE----KFSPAGPVLSIRVCRTRRSLGYAYVNFQQPADAERALDTMNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKTQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDSKGFGFVSYEKHEDANKAVEEMNGKEISGK-IIFVGRAQK 268
13 -44.800[K] KOG4210 Nuclear localization sequence binding protein  ali follow..  16  117.KKKKDENKYGVWIGNLSFDTTKDDLVR----FFIAKTKDNEDEKSRAMKNKGFCYMFFKNVEQMKAVLE-LSESHLNGRNMLIKDSENYSGRPDKDDLV-------------------------------------------------AMSKNPPSRILFVGNLSFDVTDDLLRKHFQHCGDIVKIRMATFEKGFAFIDFKNEEGSTNELKDKSCRKIAGR-PLRMEYGED 317
14 -44.400[K] KOG1548 Transcription elongation factor TAT-SF1  ali follow..  12  103..SPAPVINKAVYIQGLPLDVTVDEIEE----VFKKCGVIIKIYRTEDGTPKGDALIVFFRSESVELAEQLFDDTEFRYGSGQKMRVQKANIDYKKEKTVNKDVGGALKKKALRLRQQQMQQISSWDDVDEEVDD---------------KRKKRFNKIVVLKHI--IDLKDDITEEAEKCGRVTNVVLYDKEDGVVTVRFSNNEEAEACVRLMQGRYFDGRV-VEASI... 331
15 -43.900[K] KOG0147 Transcriptional coactivator CAPER (RRM superfamily)  ali follow..  21  143..SPEERDARTVFCMQLAARIRPRDLED----FFSAVGKVRDVRIISSRRSKGIAYVEFCEIQSVPLAIG-LTGQRLLGVPIIVQASQAEKNRLAAMANN-------------------------------------------------LQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSKGYGFITFSDSECARRALEQLNGFELAGR-PMRVGHVTE 325
16 -42.100[A] KOG0144 RNA-binding protein CUGBP1/BRUNO (RRM superfamily)  ali follow..  19  8.PDQPDLDAIKMFVGQVPRTWSEKDLRE----LFEQYGAVYEINVLRDPQSKGCCFVTFYTRKAALEAQNALHNMKVLPGMHHPIQMKPADSEKNNA---------------------------------------------------------VEDRKLFIGMISKKCTENDIRVMFSSFGQIEECRILRGSRGCAFVTFTTRAMAQTAIKAMHQAQTMCSSPMVVKFADT 188
17 -41.600[A] KOG0146 RNA-binding protein ETR-3 (RRM superfamily)  ali follow..  21  46.IPMKDHDAIKLFIGQIPRNLDEKDLKP----LFEEFGKIYELTVLKTGMHKGCAFLTYCERESALKAQSALHEQKTLPRPIQVKPADSESRGGSSCL----------------------------------------------------RQPPSQDRKLFVGMLNKQQSEDDVRRLFEAFGNIEECTILRGPKGCAFVKYSSHAEAQAAINALHGSQTMPSSSLVVKFADT 232
18 -41.500[A] KOG0131 Splicing factor 3b, subunit 4  ali follow..  20  17.HSAERNQDATVYVGGLDAQLSEELLWE----LFVQAGPVVNVYVPKTNLHQNYGFIEYRSEEDADYAIKVLNMIKLHGKPIRVNKASQDKKSLDV------------------------------------------------------------GANLFIGNLDPDVDEKLLYDTFSAFGVIASNPKIGNSRGFGFISYDSFEASDAAIESMTGQYLSNR-QITVSYAYK 191
19 -40.300[A] KOG0106 Alternative splicing factor SRp55/B52/SRp75 (RRM superfamily)  ali follow..  15  2.........VRVYIGRLPNRASDRDVEH----FFRGYGKLSDVIM-----KNGFGFVDFQDQRDADDAVHDLNGKELCGERVILEFPRRKVGYNEERSGSGFRGREPTFRKGG-----------------------------ERQFSNRYSRPCSTRFRLVIDNLSTRYSWQDIKDHIRKLGIEPTYSEAHKNVNQAIVCFTSHDDLRDAMNKLQGEDLNGRK-LKCTDETR 186
20 -39.100[A] KOG0115 RNA-binding protein p54nrb (RRM superfamily)  ali follow..  17  107VPKKKFTGRCRLFVGNLPNEVKETELKE----LFSPHGDIAECYLS----GKGFAFLRLDTRAHAESAKEAIDGRIIHGRQVRVRFAV-------------------------------------------------------------------HGAAIRVKELSPTVSNEMLYHAFSHFGDVERAVHIVDPTGEGIVEFERKPNCNEAMAAIRDKVFLSPKPLICEVLEP 270
21 -39.100[R] KOG0114 Predicted RNA-binding protein (RRM superfamily)  ali follow..  22  7.IRLPPEVNRLLYVRNLPYKITSDEMYD----IFGKFGAIRQIRVGNTPETRGTAFVVYEDIFDAKNACDHLSGFNVCNRYLVVLYYQSNKAFKR......................................................................................................................................... 96
22 -38.200[J] KOG0122 Translation initiation factor 3, subunit g (eIF-3g)  ali follow..  11  110.........RAPGTKADESKATGDGLSQ----LGKGGAVLMVCRICHDHWTSKCPYKDLAAPTDVFIDKPPTGESSTMSAAPGTGKAAYVPPSMRAGADR--------------------------------------------SAVGSDMRRRNDENSVRVTNLSEDTREPDLMELFHPFGAVTRVYVAIDQRGFGFVNFVSREDAQRAINKLNGYGYDNL-ILRVEWATP 291
23 -37.700[A] KOG0117 Heterogeneous nuclear ribonucleoprotein R (RRM superfamily)  ali follow..  20  49..AAPPERGCEIFIGKLPRDLFEDELIP----LCEKIGKIYEMRMMMNGNNRGYAFVTFSNKVEAKNAIKQLNNYEIRNGRLLGVCASVDNCRIVYPSAADKTKNRGFAFVEYESHRAAAMARRKLLPGRIQLWGHGIAVDWAEPEVEVDEDTMSSVKILYVRNLMLSTSEEMIEKEFNNIKPGAVERV-KKIRDYAFVHFSNREDAVEAMKALNGKVLDGS-PIEVTLAKP 303
24 -36.900[J] KOG0899 Mitochondrial/chloroplast ribosomal protein S19  ali follow..  14  1.......................................MESRHFATFLASKGFVDILYWVYRFQASSMAFCTKL---GGHWKQGVNVPVSSMLGSLR--------------------------------------------------------YMSTKLYIGGLSPGTDEHSLKDAFSSFNGVTEARVMTNKRGYGFVNFISEDSANSAISAMNGQELNGF-NISVNVAKD 141
25 -36.800[R] KOG4733 FOG: RRM domain  ali follow..  19  54.SGWDQLSKTNLYIRGLPPHTTDQDLVK----LCQPYGKIVSTKAILTNKCKGYGFVDFDSPAAAQKAVSALKASGVQAQMAKQQEQDPTN--------------------------------------------------------------------LYISNLPLSMDEQELENMLKPFGQVISTRILRDSRGVGFARMESTEKCEAVIGHFNGKFIKTPEPLLCKFAD. 225
26 -36.500[A] KOG0121 Nuclear cap-binding protein complex, subunit CBP20 (RRM superfamily)  ali follow..  13  23..ERSLRDSCTLYVGNLSFYTTEEQIHE----LFSRCGDVRVIVMGLKKTPCGFCFVEYYVRSEAEAAMRFVNGTRLDDRLIRVDWDAGFVEGRQYGRGK-------------------------------------------------------------TGGQVRDEYRTDYDAGRGGYGKLLSQKIAPNTDN..................................... 153
27 -35.500[D] KOG4660 Protein Mei2, essential for commitment to meiosis, and related proteins  ali follow..  23  178..PNGEHPSRTLFVRNINSSVEDSELSA----LFEPFGEIRSLYT--ACKSRGFVMISYYDIRAAHAAMRALQNTLLRKRTLDIHFSIPKENPSEKDMN---------------------------------------------------------QGTLVIFNVDTTVSNDELLQLFGAYGEIREIRETPNRRFHRFIEYYDVRDAETALKALNRSEIGGKC-IKLELSRP 343
28 -34.900[R] KOG0226 RNA-binding proteins  ali follow..  14  90.RLPTMPPVPPSIFMPPQLRAAPIMFPPR----VLGIPAPATIEGAPETPAVNAIPQELLRTQALQSDIDKMNFKKQTDPFKKKIKEQQAKKKFVRSGGGQVWEDP------------------------------------------SLAEWDENDFRVFCGDLGNEVSDELLAKAFRKYPSFQKAKVVRESKGYGFVSFRDSEDYVRAMREMDGKYV-GNRPIKLRKSAW 281
29 -34.400[AR] KOG1365 RNA-binding protein Fusilli, contains RRM domain  ali follow..  10  378..APEEKKKDCVRLRGLPYEATVQHIVT----FLGDFATMVKMVYNNQGHPSGEAFIQMINEQAASACAAGVHNNFMSKRYIEVFQASAEELNLHHLVGQQHQVPPPAPLGFMGQLPPQAPQPQQFWSSYPS--------------PPISPIVPGQVTQLIIYGIHMSIGVPELVANFTTPEHTVDVLFTRWPPGEAILTLRNRGAPPPQTSPLSQISQ-LSAPNFAAYSHH 602
30 -33.800[R] KOG0130 RNA-binding protein RBM8/Tsunagi (RRM superfamily)  ali follow..  13  66..PQRSVEGWILFVTSIHEEAQEDEIQE----KFCDYGEIKNIHLNRTGFSKGYALVEYETHKQALAAKEALNGAEIMGQTIQVDWCFVKGPKRVK........................................................................................................................................ 158
31 -33.600[R] COG0724 RNA-binding proteins (RRM domain)  ali follow..  25  183.DSRERDDMCTLKIMQVNENADENSLRE---ELLFPFAPIPRVSVVRTGKSRGLAFVTFSSEEVAEQALRFLDGRGYMNLILRVEWSKPKVKE........................................................................................................................................... 274
32 -33.400[R] KOG0154 RNA-binding protein RBM5 and related proteins, contain G-patch and RRM domains  ali follow..  14  217..WNPGVPSNKLAILNMPNDVDNTKITLSLGKC-----RTMTKFDKNTKQIRTFAFVEFSNRETAEQWMTDYEGWLTLDDGRTLAVEYAKGDPAAGSGNKGDD--------------AHCSMNNFVKRQTCFKCEISKDQSMELEKLGAHMVGMTPCDTLLIRGLPDGINNSLIFDSLGALVCLSSISMIKLSKRFAYLQMKSADEAKMLLNLTYKSPIRKDKDVQVSWCRD 440
33 -32.800[A] KOG4211 Splicing factor hnRNP-F and related RNA-binding proteins  ali follow..  11  2MLGTEGGEGFVVKVRGLPWSCSADEVQR----FFSDCKIQNGAQGIREGRPSGEAFVELESEDEVKLALKK-DRETMGHRYVEVFKSNNVEMDWVLKHTG------------------------------------------------PNSPDTANDGFVRLRGLPFGCSKEEIVQFFSGLEIVPNGITLPRSTGEAFVQFASQEIAEKALK-KHKERI-GHRYIEIFKSSR 188
34 -32.500[R] KOG1457 RNA binding protein (contains RRM repeats)  ali follow..  17  13..............................................STGTGSGAGSGGALEEEPQNLGFGRGQSCELEAGIHRGIIQWDHP-------------------------------PPPCHRHHHHHTYPNLLQDTVSVLFVHELKTRPGVRTLFVSGLPVDIKPRELYLLFRPFKGYEGSLILTARQPVGFVIFDSRAGAEAAKNALNGIRFDPEQTLRLEFAKA 170
35 -32.200[A] KOG4209 Splicing factor RNPS1, SR protein superfamily  ali follow..  12  71..EKAEADAKSVYVGNVDYGATAEEIEQ----HFHGCGSVSRVTIQCSGHPKGFAYVEFTEKEGMQNAL-AMTDSLLRGRQIKVDPKRTNKPGMSTTNRP------------------------------------------PFRGRGGRGRGNVIVKYVYAGGFRPRGRGARRRPGFAPY................................................... 205
36 -30.300[A] KOG4207 Predicted splicing factor, SR protein superfamily  ali follow..  24  6.PPPDVDGMITLKVDNLTYRTSPDSLRR----VFEKYGRVGDVYIPLTKAPRGFAFVRFHDRSDAQDAEAAMDGAVLDERELRVRMARYGRRDLPR........................................................................................................................................ 99
37 -30.000[A] KOG0107 Alternative splicing factor SRp20/9G8 (RRM superfamily)  ali follow..  18  2.............................................................................................................................................................SRVYVGNLDPRVTERELEDEFRSFGVIRSVWVARRPPGYAFLDFEDSRDARDAIREVDGKNGWRVE-QSHNRGGG 75
38 -29.300[TR] KOG4019 Calcineurin-mediated signaling pathway inhibitor DSCR1  ali follow..  11  3.EVDLQDLPSATIACHLDPRFVDGLCRAKFESLFRTYDKDITFQYF---KSFKRVRINFSNPFSAADARLQLHKTEFLGKEMKLYFAQTLHIGSSHLAPPNPDKQ----SPPASPPVGWKQVEDATPVINYDLLYAISKLGPGEKYELHAATDTTPSVVVHVCESDQEKEEEE........................................................... 171
39 -29.200[R] KOG4208 Nucleolar RNA-binding protein NIFK  ali follow..  17  1MAAFSRSA---GPILSLNPQEDAE-----LQKEVAQCDTVTRFRLSRTGNSKGYAFVEFESEDVAKIVTETMNSYLFGERLLECHFMPPEK............................................................................................................................................. 86
40 -28.500[A] KOG4205 RNA-binding protein musashi/mRNA cleavage and polyadenylation factor I complex, subunit HRP1  ali follow..  16  38..SHGSQDPGKMFIGGLSWQTTAENLRD----YFGRFGEVNECMVMATKRARGFGFITFVDPSSVDKVLNN-REHELDGKKIDPKVAFPKRTQAKLVT---------------------------------------------------------KTKKVFIGGLSATSTLEDMKQYFETYGKVEDAMLMFDHRGFGFVTFDSDEVADKVCEIINGKMVECKKAQ....... 210
41 -28.100[R] KOG4454 RNA binding protein (RRM superfamily)  ali follow..  19  5.PTPSPPEERTIYVANFSEEVDEELLEE----LFIQAGPVVKVILRDRDSNAKFALVEFEDELSVLFAIELMNGVRLFNQELQVKPRNGTNQEELYKR...................................................................................................................................... 98
42 -27.900[A] KOG0108 mRNA cleavage and polyadenylation factor I complex, subunit RNA15  ali follow..  15  1MSMTA---GNVVFVGNIPYDVSEQQMTE----IFNQVGPVKTFKLVLTGSGKGYGFCEFFDSETTAMAVRKLNNSELGPRKIRVEFPSNDPRRNQSYEYT.................................................................................................................................... 96
43 -27.300[R] KOG0126 Predicted RNA-binding protein (RRM superfamily)  ali follow..  14  29..HSEYKDSAWIFLGGLPYELTEGDIIC----VFSQYGEIVNINLVRTGKSKGFCFLCYEDQRSTILAVDNFNGIKIKGRTIRVDHVSNYR............................................................................................................................................. 116
44 -26.700[AR] KOG0109 RNA-binding protein LARK, contains RRM and retroviral-type Zn-finger domains  ali follow..  13  294.LPPRGACPDDEAVHQKPAPGGHRAG---DPLSFQAVGKVLECDII-----KNYGFVHIEDKTAAEDTIHNLHHYKLHGVNINVEASKNKSK---------------------------------------------------------------ASTKLHVGNISPTCTNQELQAKFEKYGPVIECDIV---KDYVLIHFIHMECCPQARLRTAPGMGDQCGCYQCKKEGH 450
45 -26.500[R] KOG0125 Ataxin 2-binding protein (RRM superfamily)  ali follow..  12  14.PTTTPDAMVQPFTTIPFPPPPQNGIPTEYGVPHTQ----DYAGQTGEHNLTLYGSTQAHGEQSSNSPSTQNGSLTQTEGGAQTDGQQSQTQSSENSESK------------------------------------------------------STPKRLHVSNIPFRFRDPDLRQMFGQFGKILDVEIIFNSKGFGFVTFENSADADRAREKLHGTVVEGR-KIEVNNATA 188
46 -26.100[A] KOG0533 RRM motif-containing protein  ali follow..  13  66.SRGNDSKVIRVNISNLAPTVISSDLEE----LFGDYR--VSVNFNEHGDSLGTGDISLTK-RDAERLVQKFSGVALDGKIMKFAVIDSSNMAGRVDFGNRSRSSPGRSSRGFQSGPRRNNGKPEDFLRDGVHAGDIKRGGAGRGGFRKGGRGGARDA-------KPKKTEAELDAELEAY................................................... 234
47 -25.000[J] KOG0129 Predicted RNA-binding protein (RRM superfamily)  ali follow..  13  447.GERVERYSRKVFVGGLPPDIDEDEITAS----FRRFGPLIVDWPHKYFPPKGYAFLLFQDESSVQALIDACI-EEDGKLYLCVSSPTIKDKPVQIRPWNLS----------------------------------------DSDFVMDGSQPLDPRKTIFVGGVPRPLRAVELAMIMDRYGGVCYAGIDTDPKGAGRVAFSNQQSYIAAISALQHGEIDKRVEVK...... 641
48 -24.300[R] KOG0153 Predicted RNA-binding protein (RRM superfamily)  ali follow..  22  223......................................................................................................................................................PPEDRNITTLYVGNLPEEITEPELRDQFYQFGEIRSIALVP-RQQCAFVQYTKRNAAELAAERTFNKLVIQGRKVSIKWAHS 303
49 -22.600[R] KOG4307 RNA binding protein RBM12/SWAN  ali follow..  13  599..EHTDPTRWCVQVTNVPFRMKDEELLEWFSEKVRPAK--LTRTFYSDGNASDRWVAEFSSESLMKRSFG--IRTLCTGRTLRLRYIDNAKADEILKIEDVYGEGKRQMNEEARLQHEVAEKANPPSGGFQGGSRGDDSQPSQSELMELIKSIGPRGTVLSCNGFPKDVTLEDVVEFFNDYE--NSIRIRRGDDG-CMLACQNQENARRASMDLDGQKL-RNSVISVR.... 946
50 -22.300[A] KOG0113 U1 small nuclear ribonucleoprotein (RRM superfamily)  ali follow..  16  95..NATEDPFRTLFIARINYDTSESKLRR----EFEFYGPIKKIVLIHSGKPKGYAFIEYEHERDMHAAYKHADGKKIDSKRVLVDVERARTVKGWLPR...................................................................................................................................... 189
51 -22.200[D] KOG2186 Cell growth-regulating nucleolar protein  ali follow..  17  400.SADRDIAQRNIFVRGFGWDTTQENLKTA----FESYGEIEECSVVDTGRGKGYGFVMFKTRKGAREALKRPEK-RMYNRIVVCNLASEKPGKAGKEQDM.................................................................................................................................... 496
52 -21.400[K] KOG3152 TBP-binding protein, activator of basal transcription (contains rrm motif)  ali follow..  12  2.............................................................................................................QSEESHELTDGISEEKESKETMKSQKADRKKKKLKEKLLKEASKADNRGVCYLSRIPPHMDHVRLRHILAQYGELGRIYLAPEADSEGWVEFAKKSVAKRVADMLNGEQIGGKK-WNIKYLTK 157
53 -20.500[K] KOG2068 MOT2 transcription factor  ali follow..  18  100LTSVRVVQRNLVYIVGLPLNLADEDLLQR-KEYFGQYGKVLKVSMSRTPNNTCSVYITYGKEEEAIRCIQSVHGFILDGKALKACFGTTK.............................................................................................................................................. 196
54 -20.200[R] KOG0151 Predicted splicing regulator, contains RRM, SWAP and RPR domains  ali follow..  11  26PRRRERRMKQLVCIKSPWNRFKGIMLQLRLLLEVTINPNDNKLKPDSQGMFPPFSPHHWHLRVKDQRIRDEERS------------KEMEKGKTRNIDHFVEELKREQEIRERRNQDRENSRDHNSDNTSSSRFDELPDYFDPSGRLGSLDDGDPQTTNLYVVNLSSKVDENFLLRTFGRFGPIASVKIMRRERHCGFVAFMNRADGEAAKEKMQGIIVYE-YELKIGWGKV 252
55 -19.700[R] KOG0149 Predicted RNA-binding protein SEB4 (RRM superfamily)  ali follow..  18  16.SPFGDTTFTKVFVGGLAWETQSETLRQH----FEQYGEILEAVVINTGRSKGYGFVTFRDPEAARRACAD-PTPIIDGRRANCNLASLGRPRPPLPYAV.................................................................................................................................... 112
56 -19.100[R] KOG2135 Proteins containing the RNA recognition motif  ali follow..  11  359..GAINRDNCTLQVAKIPPEMNT---IAKLNEHFATFGTVDNIQVRYNGEIDS-ALVTYASKFDAGKAYKS-PTPVLNNRFIKVFWHNPGGEGSENATGKPSSPTSPPKPVEKPKIATVQESKFVSVAAQNYRKQIQDAKERLTKEKSILSTLVQ-SSVVIVRGVTDE-LVTDLMAHMEKFGEVFDHSV-DDGLITAVFPFRKTGDALKAMA--DGKVLNGVD-LEMELKTE 683
57 -18.500[A] KOG2202 U2 snRNP splicing factor, small subunit, and related proteins  ali follow..  16  43........SPTLLLSNMKIQEHFEDFFEDLFEELGKFGEIESLNICDNDHMIGNVYVQFKEEDQAAAALQALQGRFYSGRPIIADFSPVTD............................................................................................................................................. 148
58 -18.000[A] KOG1996 mRNA splicing factor  ali follow..  15  306......CPTKVVLLRNMAGEV-DEDLEVETKEECEKYGKVGKCVIFEPDDEAVRIFLEFERVESAIKAVVDLNGRYFGGRVVKACF.................................................................................................................................................. 390
59 -17.500[R] KOG1995 Conserved Zn-finger protein  ali follow..  20  273..CDDNCDNARIYISNLPPDVTTDELKD----LFGGIGQVGKIYTDEKGNYKGDACLAYEDPSAAHSAGGFFNNYEMRGNKISVTMAEKSAPRAPTFDQS.................................................................................................................................... 382
60 -17.100[A] KOG4676 Splicing factor, arginine/serine-rich  ali follow..  15  32............................................................................................................................................................TEVIQVTNVSPSASSEQMRTLFGFLGKIDELRLFPPDDSVCFVKFHDPDSAVVAQ-HLTNTVFVDR-ALIVVPYAE 112
61 -16.700[T] KOG0116 RasGAP SH3 binding protein rasputin, contains NTF2 and RRM domains  ali follow..  12  206......................................................................................DKSNGVDAPKKSFAHIVQDLAQNGATFNAKASPAKPKSKPVTKPSAARESKAPAPVSEHSSAATIDQQAEGYTIFVANLLMDATPEQLNETFKGFGAITKDGIQVRSNCFGFVTFASAEAVKLVLQAHKESAIRGNRRVSIEEKRG 357
62 -16.400[J] KOG2314 Translation initiation factor 3, subunit b (eIF-3b)  ali follow..  19  56........GNIIVVDHLPPKEKFEKLEGVVKKIYNQLGVIKENGLLDTKMTLGYCFIEFNTPQEAQNAKEKSHGYKLDKS........................................................................................................................................................ 134
63 -15.800[A] KOG4849 mRNA cleavage factor I subunit/CPSF subunit  ali follow..  10  85.LTPTMNRRYQLYVGNLTWWTTDQDIANSL----RDIGDLQEVKFFENGQSKGFSVISLGSESSLRAVLDQLPKKEMHGQAPVVTYPSKQALTQFESLQKTRPVPPPQQNGPPRGPAPPSMGGGPMPTGHPGGPQGGGPPGHPPRGMNSIMQPGQYR........................................................................... 241
64 -15.200[K] KOG4661 Hsp27-ERE-TATA-binding protein/Scaffold attachment factor (SAF-B)  ali follow..  14  399..KGRSSCGRNFWVSGLSSTTRATDLKN----LFSKYGKVVGAKVVTNARARCYGFVTMSTAEEATKCINHLHKTELHGKMISVEKAKNEPVGKKTSDKRDSDGKKEKSSNSD....................................................................................................................... 508
65 -15.000[A] KOG4213 RNA-binding protein La  ali follow..  11  6..............DNEKMAALEAKICHQIEYYFGD-FNLPRDKFLKEQIKLDEGWVKFNRLNRLTTDFNVIVEALSKSKAELMEISEDKTKIRRSPS--------------------------------------------PLPEVTDEYKNDVKNRSVYIKGFPTDATLDDIKEWLEDKGQVLNIQMRRTLKGSIFVVFDSIESAKKFVETPG................. 172
66 -13.200[R] KOG2295 C2H2 Zn-finger protein  ali follow..  6  417...........................................................ATKAKQGPQSPKLDEDEGNENTEPKGLDSKINTYEEIDNTLKSPEISSNPIKNTDNGDGSKVEEDGEKPSVGKDKVVETETIDLDKVKDGQPRALHRTSSIFLRNLAPSITRSEIEAVCNRFSGYLRVAIADPLVRRGWITFMRDVNIKEICWGLNNQRL-RDCEMGAIVNRD 593
67 -13.100[A] KOG4008 rRNA processing protein RRP7  ali follow..  9  39......................................................................................................................................................KKDPSKENSIIVSNIPAFVGEGVVLAIIDQFASFEVEESFVQRSNTMSITFDKPEAVIQTLALCQ................. 114
68 -12.800[R] KOG4198 RNA-binding Ran Zn-finger protein and related proteins  ali follow..  13  235ARSFYAERSKIVHVAGLTNDVTQLELESWFTNHGVHPVALWTLKTPEPYKSTGTGFVLFASHEDAADALA-FNGYCLGDRMLEIIPSSTKVLDKASDILIPFPSSKNRPRPGD....................................................................................................................... 346
69 -12.500[S] KOG4176 Uncharacterized conserved protein  ali follow..  14  34..SPSAEPTPYLAVLNLSNGLTEECLLTEA---AATGGKVIQVVML---PGKSYCFFICASLEDSQLIYEGMHNISTIGQQ....................................................................................................................................................... 108
70 -12.000[K] COG5175 Transcriptional repressor  ali follow..  17  128LSGTRVIQKNLVYVVGINPPVPYEEVAPTLKKYFGQYGKINKIVVNRKTPHSN-VYITFGSKDDAARCIAQVDGTYMDGRLIKAAYGTTK.............................................................................................................................................. 233
71 -11.200[R] KOG2891 Surface glycoprotein  ali follow..  13  26.......PLAKMQISKSGKSVSNLEIMDKLGAELKP--KFLLLKVSKSTVN----TIRLEERKRLRAAIQRLDGISLRSESFRVRCAESKDDFPTRHDWDSYFRDARNMDEMKAGERP---------------------------------------DTIHISHLPVKPSENIFKRIFEKFGRVRMVDIPICDP--GYVQFEEYSSFVRAMDEFRGNKLVRKFNICVSFDKQ 263
72 -10.000[A] COG5107 Pre-mRNA 3`-end processing (cleavage and polyadenylation) factor  ali follow..  7  462..QNDYKTAFKVLELGLKYFQNDGVYINKYLDFLIFLNKDSQIKTLFETSVEKVKMISYESKFGNLNNVYSLEKRFFE-EVFTSRYQIQNSNLIKKLELTYMYNEEEDSYFSSGNGDGHHGSYNMSSSDRKRLMEETGNNGNFSNKKFKRDSELPTEVLDLLSVIPKRLDAQKLVNFLNDQVEIPTVESTKS........................................ 676
73 -9.810[R] KOG1855 Predicted RNA-binding protein  ali follow..  14  274..............SLIPSEELAAEITDAVEFYFSNESILKDAFLLKHVRRNKEGFVSL----KLVSSFKRVRQLTREWKVVGDAVRRKSRKIELNDVGTKVRRIEP-----------------------------------------PSFDETMPSRTIVACDLPLDLTIEKVSDLFSPCGEIALIRILKQQKECALVEYLESSSARDARHLNG................. 450
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Ye Y, Godzik A. Multiple flexible structure alignment using partial order graphs. Bioinformatics. 2005 Mar 3;