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Query: [A] KOG4207 Predicted splicing factor, SR protein superfamily, from COG1018

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MSCGRPPPDVDGMITLKVDNLTYRTSPDSLRRVFEKYGRVGDVYIPLEPHTKAPRGFAFVRFHDRSDAQDAEAAMDGAVLDERELRVRMARYGRRDLPRSSQEEPRGRSWGGRYGRRSGSPRGRHRSQSRGPSYSRSRSRSHYGGSRYSLSIYRRSRYSRSPYRRSHYRGSRYGRSPYSRSYSRHHYSRSPYRESRYRRSPYIRSSRSRSPYRRSHSKSGSHSASPSTSKSSSPLast
1 -66.900[A] KOG4207 Predicted splicing factor, SR protein superfamily  ali  100  1MSCGRPPPDVDGMITLKVDNLTYRTSPDSLRRVFEKYGRVGDVYIPLEPHTKAPRGFAFVRFHDRSDAQDAEAAMDGAVLDERELRVRMARYGRRDLPRSSQEEPRGRSWGGRYGRRSGSPRGRHRSQSRGPSYSRSRSRSHYGGSRYSLSIYRRSRYSRSPYRRSHYRGSRYGRSPYSRSYSRHHYSRSPYRESRYRRSPYIRSSRSRSPYRRSHSKSGSHSASPSTSKSSSP 234
2 -50.700[R] KOG0126 Predicted RNA-binding protein (RRM superfamily)  ali follow..  14  29......HSEYKDSAWIFLGGLPYELTEGDIICVFSQYGEIVNINLVRDKKTGKSKGFCFLCYEDQRSTILAVDNFNGIKIKGRTIRVDHVSNYRAPKDSEEIDDVTRQLQEKGCGARTPSPSLSESSEDEKPTKKHKKDKKEKKKKKKEKEKADREVQAEQPSSSSPRRKTVKEKDDTGPKKHSSKNSERAQKSEPREGQKLPKSRTAYSGGAEDLERELKKEKPKHEHKSSS. 255
3 -47.100[J] KOG0122 Translation initiation factor 3, subunit g (eIF-3g)  ali follow..  31  201.AVGSDMRRRNDENSVRVTNLSEDTREPDLMELFHPFGAVTRVYVAIDQKTGVSRGFGFVNFVSREDAQRAINKLNGYGYDNLILRVEWATPR............................................................................................................................................. 292
4 -46.600[R] COG0724 RNA-binding proteins (RRM domain)  ali follow..  25  179.DAYRDSRERDDMCTLKIMQVNENADENSLRELLFPFAPIPRVSVVRNKETGKSRGLAFVTFSSEEVAEQALRFLDGRGYMNLILRVEWSKPKVKE.......................................................................................................................................... 274
5 -44.600[J] KOG0899 Mitochondrial/chloroplast ribosomal protein S19  ali follow..  20  51.VSSMLGSLRYMSTKLYIGGLSPGTDEHSLKDAFSSFNGVTEARVMTNKVTGRSRGYGFVNFISEDSANSAISAMNGQELNGFNISVNVAKDWPSLPLSLDE.................................................................................................................................... 151
6 -44.400[A] KOG0108 mRNA cleavage and polyadenylation factor I complex, subunit RNA15  ali follow..  20  2........SMTAGNVVFVGNIPYDVSEQQMTEIFNQVGPVKTFKLVLDPETGSGKGYGFCEFFDSETTAMAVRKLNNSELGPRKIRVEFPSNDPRRNQSYEYTERTDRYMEQQNAHES.................................................................................................................... 111
7 -42.300[A] KOG0107 Alternative splicing factor SRp20/9G8 (RRM superfamily)  ali follow..  20  2.............SRVYVGNLDPRVTERELEDEFRSFGVIRSVWVARR-----PPGYAFLDFEDSRDARDAIREVDGKNGWRVEQSHNRGGGGGRGGGRGGGDGGRGRGGSDLKCYECGESGHFARECRSRGGSGGRRRSRSRSRSPPRYRKSPTYGGRRSYSPRARSPPPPRRRSPSPRGRNYSRSPPPYRARDEVPYANGNGLKDVRRSRS..................... 196
8 -42.200[R] KOG0226 RNA-binding proteins  ali follow..  22  200..........ENDFRVFCGDLGNEVSDELLAKAFRKYPSFQKAKVVRESRTNKSKGYGFVSFRDSEDYVRAMREMDGKYVGNRPIKLRKSAWKERNIDVIKQKRKQKKELG........................................................................................................................... 300
9 -42.100[R] KOG4454 RNA binding protein (RRM superfamily)  ali follow..  16  1MEIK-PTPSPPEERTIYVANFSEEVDEELLEELFIQAGPVVKVILRDV--RDSNAKFALVEFEDELSVLFAIELMNGVRLFNQELQVKPRNGTNQEELYKRKKGEIEERVRSVAAPDRDGRRDSYRDDRNRNRNGNNRDSWQQQQPPRHHRQYDPLPPPPPPPLMGGSGGHWRSGGERGPPQYSTPQMLPHQHFVNQMMQQQINRSAPPYNGRHQNSTPHRHHDRHGYDRSSS. 230
10 -41.800[A] KOG0106 Alternative splicing factor SRp55/B52/SRp75 (RRM superfamily)  ali follow..  25  2.............VRVYIGRLPNRASDRDVEHFFRGYGKLSDVIM--------KNGFGFVDFQDQRDADDAVHDLNGKELCGERVILEFPRRKVGYNEERSGSGFRGREPTFRKGGERQFSNRYSRPCSTRFR-TDETRDRSRSRSPRRRSRSRSPTRSRSPPARRRSPGSDRSDRKSRSASPKKRSDKRARSESKSRSRSGGRRSRSNSPPNRSPSPKKRRDNSSPRSGSASP 281
11 -41.400[R] KOG0130 RNA-binding protein RBM8/Tsunagi (RRM superfamily)  ali follow..  19  61.ELEPGPQRSVEGWILFVTSIHEEAQEDEIQEKFCDYGEIKNIHLNLDRRTGFSKGYALVEYETHKQALAAKEALNGAEIMGQTIQVDWCFVKGPKRVKKSEKRRR................................................................................................................................ 165
12 -40.600[A] KOG0113 U1 small nuclear ribonucleoprotein (RRM superfamily)  ali follow..  16  92...EIKNATEDPFRTLFIARINYDTSESKLRREFEFYGPIKKIVLIHDQESGKPKGYAFIEYEHERDMHAAYKHADGKKIDSKRVLVDVERARTVKGWLPRRLGGGLGGTRRGGNDVNIKHSGREDNERERERYRLEREREDREGPGRGGGSNGLDARPGRGFGAERRRSRSRERRDRERDRGRGAVASNGRSRSRSRERRKRRAGSRERYDEFDRRDRRDRERERDRDRERE. 321
13 -39.300[D] KOG2186 Cell growth-regulating nucleolar protein  ali follow..  17  399....ESADRDIAQRNIFVRGFGWDTTQENLKTAFESYGEIEECSVVMDKDTGRGKGYGFVMFKTRKGAREALKRPE-KRMYNRIVVCNLASEKPGKAGKEQD.................................................................................................................................... 495
14 -39.200[A] KOG0121 Nuclear cap-binding protein complex, subunit CBP20 (RRM superfamily)  ali follow..  25  18.SRSEQERSLRDSCTLYVGNLSFYTTEEQIHELFSRCGDVRVIVMGLDKYKKTPCGFCFVEYYVRSEAEAAMRFVNGTRLDDRLIRVDWDAGFVEGRQYGRGKTG................................................................................................................................. 121
15 -38.800[A] KOG4209 Splicing factor RNPS1, SR protein superfamily  ali follow..  23  65SLLTPEEKAEADAKSVYVGNVDYGATAEEIEQHFHGCGSVSRVTIQCDRFSGHPKGFAYVEFTEKEGMQNAL-AMTDSLLRGRQIKVDPKRTNKPGMSTTNRPPFRGRGGRGRGN....................................................................................................................... 178
16 -37.900[R] KOG0125 Ataxin 2-binding protein (RRM superfamily)  ali follow..  24  100.QSSENSESKSTPKRLHVSNIPFRFRDPDLRQMFGQFGKILDVEIIFNE--RGSKGFGFVTFENSADADRAREKLHGTVVEGRKIEVNNATARVMTNKKMVT.................................................................................................................................... 198
17 -37.500[K] KOG4210 Nuclear localization sequence binding protein  ali follow..  17  227.DDLVAMSKNPPSRILFVGNLSFDVTDDLLRKHFQHCGDIVKIRMATFEDSGKCKGFAFIDFKNEEGSTNELKDKSCRKIAGRPLRMEYGEDRSKRQVRKKVENVSRNNSSS.......................................................................................................................... 337
18 -37.200[A] KOG0144 RNA-binding protein CUGBP1/BRUNO (RRM superfamily)  ali follow..  19  384IGAAGSQKEGPEGANLFIYHLPQEFGDQDLLQMFMPFGNVVSAKVFIDKQTNLSKCFGFVSYDNPVSAQAAIQSMNGFQIGMKRLKVQLKRSKNDSKP........................................................................................................................................ 481
19 -36.300[R] KOG0110 RNA-binding protein (RRM superfamily)  ali follow..  24  352.DSLSKEDDISESGRIFFRNLAYTTTEEDLRKLFEQFGPVVEVNLPLDKLTRKIKGFGTVTYMMPEHALKAFNTLDGTDFHGRLLHLLPSKDIEKNPKE....................................................................................................................................... 449
20 -36.000[A] KOG0105 Alternative splicing factor ASF/SF2 (RRM superfamily)  ali follow..  25  1MSGWADERGGEGDGRIYVGNLPTDVREKDLEDLFYKYGRIREIELKNR---HGLVPFAFVRFEDPRDAEDAIYGRNGYDYGQCRLRVEFPRTYGGRGGWPRGGRNGPPTRRSD......................................................................................................................... 110
21 -35.900[A] KOG2202 U2 snRNP splicing factor, small subunit, and related proteins  ali follow..  15  77.....................HFEDFFEDLFEELGKFGEIESLNICDNL-ADHMIGNVYVQFKEEDQAAAALQALQGRFYSGRPIIADFSPVTDFREATCRQYEENNCNRGGYCNFMHVKLVSRELRRKLFGRYRRSYRRGSRSRSRSRSISPRNKRDNDRRDPSHREFSHRDRDREFYRHGSGKRSSERSERQERDGSRGRRQASPKRGGSPGGGREGSEERRARIEQWNRE. 287
22 -35.400[A] KOG0145 RNA-binding protein ELAV/HU (RRM superfamily)  ali follow..  22  284LVGMNIPGHTGTGWCIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTNKAHKS......................................................................................................................................... 380
23 -35.400[R] KOG0149 Predicted RNA-binding protein SEB4 (RRM superfamily)  ali follow..  25  12.HYLNSPFGDTTFTKVFVGGLAWETQSETLRQHFEQYGEILEAVVIADKNTGRSKGYGFVTFRDPEAARRACAD-PTPIIDGRRANCNLASLGRPRPPLPYA.................................................................................................................................... 111
24 -35.400[R] KOG0114 Predicted RNA-binding protein (RRM superfamily)  ali follow..  19  3.KRNHIRLPPEVNRLLYVRNLPYKITSDEMYDIFGKFGAIRQIRV---GNTPETRGTAFVVYEDIFDAKNACDHLSGFNVCNRYLVVLYYQSNKAFKRVDMDKKQEELNNIKAKYNLKTPEA................................................................................................................ 120
25 -35.200[A] KOG4212 RNA-binding protein hnRNP-M  ali follow..  26  641.AGGHAPGVARKACQIFVRNLPFDFTWKMLKDKFNECGHVLYADIKME--NGKSKGCGVVKFESPEVAERACRMMNGMKLSGREIDVRIDRNA............................................................................................................................................. 730
26 -34.700[A] KOG0120 Splicing factor U2AF, large subunit (RRM superfamily)  ali follow..  18  199.....STVVPDSPHKIFIGGLPNYLNDDQVKELLLSFGKLRAFNLVKDAATGLSKGYAFCEYVDLSITDQSIAGLNGMQLGDKKLIVQRASVGAKNA......................................................................................................................................... 290
27 -34.500[AJ] KOG0148 Apoptosis-promoting RNA-binding protein TIA-1/TIAR (RRM superfamily)  ali follow..  21  83.TPSSQKKDTSNHFHVFVGDLSPQITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAPKS....................................................................................................................................... 180
28 -34.300[R] KOG1457 RNA binding protein (contains RRM repeats)  ali follow..  23  80VLFVHELKTRPGVRTLFVSGLPVDIKPRELYLLFRPFKGYEGSLIKLT----ARQPVGFVIFDSRAGAEAAKNALNGIRFDPENLRLEFAKANTKMAKS....................................................................................................................................... 177
29 -34.000[A] KOG0128 RNA-binding protein SART3 (RRM superfamily)  ali follow..  19  671.RVGFKFSTTLEKSKVFVRNVHFQATDDELKALFSKFGTVTSVRRVTHK-DGKPKGIAFVDFDTEASAQKCVASGDKLMLRERELEVALSNPPVKKDKSHGKPAAIGASLEEDGPRKGHAAKLQLVPRAITNKTPQITARLDAMDVSEGTSTSQPLSNDQ.......................................................................... 828
30 -33.800[A] KOG0124 Polypyrimidine tract-binding protein PUF60 (RRM superfamily)  ali follow..  20  216...DQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKAVTPPMPLLTPATPGG................................................................................................................................. 317
31 -33.300[R] KOG4208 Nucleolar RNA-binding protein NIFK  ali follow..  12  2........AAFSRSAGPILSLNP-QEDAELQKEVAQCDTVTRFRLSRKKRTGNSKGYAFVEFESEDVAKIVTETMNSYLFGERLLECHFMPPEKKMESISKTNHRMSTKGQVLRKKKKKVLGTPD............................................................................................................. 117
32 -33.300[A] KOG0146 RNA-binding protein ETR-3 (RRM superfamily)  ali follow..  18  42.NPSTIPMKDHDAIKLFIGQIPRNLDEKDLKPLFEEFGKIYELTVLKDRFTGMHKGCAFLTYCERESALKAQSALHEQKTMNRPIQVKPADSESRGGSSCLRQPPSQDRK............................................................................................................................ 153
33 -33.100[K] KOG0147 Transcriptional coactivator CAPER (RRM superfamily)  ali follow..  22  235.MANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQLNGFELAGRPMRVGHVTERLDGGTD....................................................................................................................................... 332
34 -32.300[R] KOG0118 FOG: RRM domain  ali follow..  17  161.RTSMAQREDVIRRTVYVSDLDQQVTEEQLAGLFVSCGQVVDCRICGD--PNSVLRFAFIEFTDEEGAMTAL-NLSGTMLGFYPVKVLPSKTAIAPVNPTFLPRTEDEREMCART....................................................................................................................... 271
35 -32.000[K] KOG4661 Hsp27-ERE-TATA-binding protein/Scaffold attachment factor (SAF-B)  ali follow..  12  394.LSKEEKGRSSCGRNFWVSGLSSTTRATDLKNLFSKYGKVVGAKVVTNARSPGARCYGFVTMSTAEEATKCINHLHKTELHGKMISVEKAKNEPVGKKTSDKRDSDGKKEKSSNSDRSTNLKRDDKCDRKDDAKKGDDGSGEKSKDQDDQKPGPSERSRATKSGSRGTERTVVMDKSKGVPVISVKTSGSKERASKSQDRKSASREKRSVVSFDKVKEPRKSRDSESHSRVRE. 625
36 -31.300[A] KOG1190 Polypyrimidine tract-binding protein  ali follow..  8  47.FKGDSRSAGVPSRVIHIRKLPIDVTEGEVISLGLPFGKVTNLLMLKG------KNQAFIEMNTEEAANTMVNYYTSVTPRGQPIYIQFSNHKELKTDSSPN.................................................................................................................................... 143
37 -31.300[AJ] KOG0123 Polyadenylate-binding protein (RRM superfamily)  ali follow..  20  2....NAAASSYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTMNFDVIKGKPIRIMWSQRDPSLRKS....................................................................................................................................... 96
38 -31.100[A] KOG0533 RRM motif-containing protein  ali follow..  12  62.HGISSRGNDSKVIRVNISNLAPTVISSDLEELFGDYR-LSSVSVNFNE-HGDSLGTGDISLTK-RDAERLVQKFSGVALDGKIMKFAVIDSSNMAGRVDFGNRSRSSPGRSSRGFQSGPRRNNGKPEDFLRDGVHAGDIKRGGAGRGGFRKGGRGGARDAKPKKTEAE................................................................. 226
39 -30.600[A] KOG0131 Splicing factor 3b, subunit 4  ali follow..  22  13.LLGQHSAERNQDATVYVGGLDAQLSEELLWELFVQAGPVVNVYVPKDRVTNLHQNYGFIEYRSEEDADYAIKVLNMIKLHGKPIRVNKASQDKKSLDV....................................................................................................................................... 110
40 -30.300[A] KOG4206 Spliceosomal protein snRNP-U1A/U2B  ali follow..  24  2.....LTADIPPNQSIYIQNLNERIKKEELKRLFSQFGRILDVVALK---TPKLRGQAWVTFSEVTAAGHAVRQMQNFPFYDKPMRLQYAKAKSDCLAK....................................................................................................................................... 96
41 -29.700[K] KOG1548 Transcription elongation factor TAT-SF1  ali follow..  15  103......SPAPVINKAVYIQGLPLDVTVDEIEEVFKKCGVIAKNIDNGTPEDGTPKGDALIVFFRSESVELAEQLFDDTEFRYGSGQKMRVQKANIDYKKEKTVNKDVGGALKKKALR..................................................................................................................... 220
42 -28.800[T] KOG0116 RasGAP SH3 binding protein rasputin, contains NTF2 and RRM domains  ali follow..  15  265.SSAATIDQQAEGYTIFVANLLMDATPEQLNETFKGFGAITKDGIQVRSYRLKGNCFGFVTFASAEAVKLVLQAESAIRIGNRRVSIEEKRGNNDNGRPAMRNGGYRNDNGYRNDGYRPRGNGSNGGRGYGRNGSERRGESRNGEAHNGDGKVHQNGTVEASR....................................................................... 428
43 -28.800[R] KOG0153 Predicted RNA-binding protein (RRM superfamily)  ali follow..  21  222.....EPPEDRNITTLYVGNLPEEITEPELRDQFYQFGEIRSIALVPR------QQCAFVQYTKRNAAELAAERTNKLVIQGRKVSIKWAHSQAKQGTAAKT.................................................................................................................................... 313
44 -27.600[R] KOG4733 FOG: RRM domain  ali follow..  19  49SSSSNSGWDQLSKTNLYIRGLPPHTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPAAAQKAVSALKASGVQAQMAKQQEQDPTN............................................................................................................................................ 142
45 -27.200[K] KOG2068 MOT2 transcription factor  ali follow..  14  107...........QRNLVYIVGLPLNLADEDLKEYFGQYGKVLKVSMSRTQQFPNNTCSVYITYGKEEEAIRCIQSVHGFILDGKALKACFGTTK............................................................................................................................................. 196
46 -26.700[A] KOG4205 RNA-binding protein musashi/mRNA cleavage and polyadenylation factor I complex, subunit HRP1  ali follow..  21  35...DDGSHGSQDPGKMFIGGLSWQTTAENLRDYFGRFGEVNECMVMRDPATKRARGFGFITFVDPSSVDKVLNN-REHELDGKKIDPKVAFPKRTQAKLVTK.................................................................................................................................... 132
47 -26.300[A] KOG0117 Heterogeneous nuclear ribonucleoprotein R (RRM superfamily)  ali follow..  17  48.....DAAPPERGCEIFIGKLPRDLFEDELIPLCEKIGKIYEMRMMMDF-NGNNRGYAFVTFSNKVEAKNAIKQLNNYEIRNGRLLGVCASVDNCR.......................................................................................................................................... 137
48 -24.900[A] KOG0115 RNA-binding protein p54nrb (RRM superfamily)  ali follow..  31  106...EVPKKKFTGRCRLFVGNLPNEVKETELKELFSPHGDIAECYLS-------GKGFAFLRLDTRAHAESAKEAIDGRIIHGRQVRVRFAVHGAA........................................................................................................................................... 190
49 -24.000[A] KOG4211 Splicing factor hnRNP-F and related RNA-binding proteins  ali follow..  16  286..........TTGHCVHMRGLPYRATENDIYNFFSPLN-PVRVHIEIGP-DGRVTGEADVEFATHEDAVAAM-SKDKANMQHRYVELFLNSTAGASGGAYEHRYVELFLNSTAGASGG.................................................................................................................... 390
50 -23.800[AR] KOG1365 RNA-binding protein Fusilli, contains RRM domain  ali follow..  13  165.LEDQEVGADGDNVVCRARGLPWQASDHHVAQFFAGLDIVPGGIALCLSSEGRRNGEVLVQFSSQESRDLAL-KRHRNFLLSRYIEVYKAGLDE............................................................................................................................................ 256
51 -23.300[R] KOG0151 Predicted splicing regulator, contains RRM, SWAP and RPR domains  ali follow..  25  159.RLGSLDDGDPQTTNLYVVNLSSKVDENFLLRTFGRFGPIASVKIMWPREKRRERHCGFVAFMNRADGEAAKEKMQGIIVYEYELKIGWGKV.............................................................................................................................................. 252
52 -23.200[A] KOG4849 mRNA cleavage factor I subunit/CPSF subunit  ali follow..  16  81.SSGSLTPTMNRRYQLYVGNLTWWTTDQDIANSLRDIGDLQEVKFFENRANGQSKGFSVISLGSESSLRAVLDQLPKKEMHGQAPVVTYPSKQA............................................................................................................................................ 175
53 -22.900[R] KOG1995 Conserved Zn-finger protein  ali follow..  21  268.QCDADCDDNCDNARIYISNLPPDVTTDELKDLFGGIGQVGRIKIYTD-EKGNYKGDACLAYEDPSAAHSAGGFFNNYEMRGNKISVTMAEKSAPRAPT....................................................................................................................................... 378
54 -22.300[A] KOG1996 mRNA splicing factor  ali follow..  19  306..........CPTKVVLLRNMAGEVDEDETKEECEKYGKVGKCVIFEIPGAPDD-VRIFLEFERVESAIKAVVDLNGRYFGGRVVKACFYNLDK............................................................................................................................................ 395
55 -22.200[K] KOG3152 TBP-binding protein, activator of basal transcription (contains rrm motif)  ali follow..  14  40...LKEASKADNRGVCYLSRIPPHMDHVRLRHILAQYGELGRIYLAAGGFRGQRFSEGWVEFAKKSVAKRVADMLNGEQIGGKKKS.................................................................................................................................................... 143
56 -21.800[A] KOG4676 Splicing factor, arginine/serine-rich  ali follow..  20  33.............EVIQVTNVSPSASSEQMRTLFGFLGKIDELRL-DDSPLPVSSRVCFVKFHDPDSAVVAQ-HLTNTVFVDRALIVV-SAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSRHRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKE. 377
57 -21.600[J] KOG2314 Translation initiation factor 3, subunit b (eIF-3b)  ali follow..  22  44YQDDQSEFDTGFGNIIVVDHLPVVPKEK-VKKIYNQLGVIKELLMPVDPDTKMTLGYCFIEFNTPQEAQNAKEKSHGYKLDKSIFAVNMFDDFDR........................................................................................................................................... 147
58 -21.100[R] KOG0154 RNA-binding protein RBM5 and related proteins, contain G-patch and RRM domains  ali follow..  9  350EKLGAHMVGMTPCDTLLIRGLPDGINNSLIFDSLGALVCLSSI---SMIKLSESKRFAYLQMKSADEAKMLLNLTYKSRIKDKDVQVSWCRDS............................................................................................................................................. 441
59 -20.900[TR] KOG4019 Calcineurin-mediated signaling pathway inhibitor DSCR1  ali follow..  13  2....EEVDLQDLPSATIACHLDPRVFVDGFESLFRTYDKDITFQYF------KSFKRVRINFSNPFSAADARLQLHKTEFLGKEMKLYFAQTLHIGS......................................................................................................................................... 93
60 -20.400[D] KOG4660 Protein Mei2, essential for commitment to meiosis, and related proteins  ali follow..  21  257IPKENPSEKDMNQGTLVIFNVDTTVSNDELLQLFGAYGEIREI-----RETPNRRFHRFIEYYDVRDAETALKALNRSEIGGKCIKLELSRPGGARR......................................................................................................................................... 348
61 -20.200[R] KOG4307 RNA binding protein RBM12/SWAN  ali follow..  14  869..........PRGTVLSCNGFPKDVTLEDVVEFFNDY-EPDRIRIRRGDD-GVMTGECMLACQNQENARRASMDLDGQKLRNSVISV................................................................................................................................................... 945
62 -20.000[J] KOG0129 Predicted RNA-binding protein (RRM superfamily)  ali follow..  17  443.SHQNGERVERYSRKVFVGGLPPDIDEDEITASFRRFGPLIVDWPHKAKSYFPPKGYAFLLFQDESSVQALIDACI-EEDGKLYLCVSSPTIKDKP.......................................................................................................................................... 538
63 -19.000[AR] KOG0109 RNA-binding protein LARK, contains RRM and retroviral-type Zn-finger domains  ali follow..  15  290.LPPPLPPRGACPDDEAVHQKPAPGHRAGDPLSFQAVGKVLECDII--------KNYGFVHIEDKTAAEDTIHNLHHYKLHGVNINVEASKNKSKASTK....................................................................................................................................... 380
64 -16.800[R] KOG4198 RNA-binding Ran Zn-finger protein and related proteins  ali follow..  21  240.........AERSKIVHVAGLTNDVTQLELESWFTNHGHPVALWTLKTPEPYKSTGTGFVLFASHEDAADAL-AFNGYCLGDRMLEIIPSSTKVLDKASDILIPFPSSKNRPRPGD...................................................................................................................... 346
65 -16.400[O] KOG0415 Predicted peptidyl prolyl cis-trans isomerase  ali follow..  14  230....KDADEVPPENVLFVCKLNPVTTDEDLEIIFSRFGKINNCEIVRDRRSGDSLQYAFIEFDNAKSCEQAFFKMDNVLIDDRRIHVDFSQSVSQNYKYKPKSQQQEAPKRRQSPQRRPEVKRSHQRSPSPRRRRSPSPKKDKKRDYRREPARRRR.............................................................................. 381
66 -15.500[R] KOG2135 Proteins containing the RNA recognition motif  ali follow..  18  355..GGFTGAINRDNCTLQVAKIPPENTIAKLNEHFATFGTVDNIQVRYNGEIDS----ALVTYASKFDAGKAYKSPT-PVLNNRFIKVFWHNPGGEGSENATG.................................................................................................................................... 450
67 -15.400[A] KOG4213 RNA-binding protein La  ali follow..  17  110............NRSVYIKGFPTDATLDDIKEWLEDKGQVLNIQMRRTL-HKAFKGSIFVVFDSIESAKKFVETPG.............................................................................................................................................................. 172
68 -14.200[K] COG5175 Transcriptional repressor  ali follow..  17  135...........QKNLVYVVGINPPVPYEEVEKYFGQYGKINKIVVNRYHHHSPGYG-VYITFGSKDDAARCIAQVDGTYMDGRLIKAAYGTTK............................................................................................................................................. 233
69 -14.100[O] KOG0111 Cyclophilin-type peptidyl-prolyl cis-trans isomerase  ali follow..  32  2.........ATTKRVLYVGGLAEEVDDKVLHAAFIPFGDITDIQIPLDYETEKHRGFAFVEFELAEDAAAAIDNMNESELFGRTIRVNLAKPMR............................................................................................................................................ 86
70 -14.100[R] KOG2295 C2H2 Zn-finger protein  ali follow..  11  503.VKDGQPRALHRTSSIFLRNLAPSITRSEIEAVCNRFSGYLRVAIADPLVERRWYRRGWITFMRDVNIKEICWGLNNQRLRDCEMGAIVNRDLSRR.......................................................................................................................................... 597
71 -12.500[R] KOG2891 Surface glycoprotein  ali follow..  14  143..........ERPDTIHISHLPMR-SENIFKRIFEKFGRVRMVDIPICDPYRKSM--GYVQFEEYSSFVRAMDEFRGNKLVDKTQAINICVSFDKQKHLSDSNIQRRERIRKKFIAKAKAEDEEREKLKKQQEEELDRERQKQEELKKAEAEKQREREERRKEKHMKKIQERGQVEISQKIRIEERKLMIAQRKLESIRTLEKLFERIQLKQRDKNRRVKQDDDKDIQRGR... 398
72 -12.400[A] KOG4008 rRNA processing protein RRP7  ali follow..  7  39......KKDPSKENSIIVSNIPAFVGEGVVLAIIDQFASFEVEESFVDNSLSQGQLTMSITFDKPEAVIQTLALCQ.............................................................................................................................................................. 114
73 -10.700[AR] KOG2193 IGF-II mRNA-binding protein IMP, contains RRM and KH domains  ali follow..  21  2.............NKLYIGNLNESVTPADLEKVFAEHKISYSGQFLVK------SGYAFVDCPDEHWAMKAIETFSGVELQGKRLEIEHSVPKKQRS......................................................................................................................................... 80
74 -9.850[S] KOG4610 Uncharacterized conserved protein  ali follow..  12  353..............................................................ERGGDVKKKIKRAKDKDYAEQEAVYSKKKKDKKDKKKRKRKDTGYSTASSQNLYSTKASGTDKDTRRKDKKGKKSKRTCSSSPSDCDLAKKQKRKNADKNDKKKSRKIEAVVEESSSSSSSSSDSSNSTLPSYEVIDEKKARRRKHRGSSSDTSSGDSSSSSSSSSSSDSS. 523
75 -9.690[S] KOG4176 Uncharacterized conserved protein  ali follow..  16  36........SAEPTPYLAVLNLSNGLTEECLTEAAATGGKVIQVVML------PGKSYCFFICASLEDSQLIYEGMHNISTIGQQ...................................................................................................................................................... 108
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Ye Y, Godzik A. Multiple flexible structure alignment using partial order graphs. Bioinformatics. 2005 Mar 3;