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Query: [A] KOG4213 RNA-binding protein La, from COG1018

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MAENGDNEKMAALEAKICHQIEYYFGDFNLPRDKFLKEQIKLDEGWVPLEIMIKFNRLNRLTTDFNVIVEALSKSKAELMEISEDKTKIRRSPSKPLPEVTDEYKNDVKNRSVYIKGFPTDATLDDIKEWLEDKGQVLNIQMRRTLHKAFKGSIFVVFDSIESAKKFVETPGQKYKETDLLILFKDDYFAKKNEERKQNKVEAKLRAKQEQEAKQKLEEDAEMKSLEEKIGCLLKFSGDLDDQTCREDLHILFSNHGEIKWIDFVRGAKEGIILFKEKAKEALGKAKDANNGNLQLRNKEVTWEVLEGEVEKEALKKIIEDQQESLNKWKSKGRRFKGKGKGNKAAQPGSGKGKVQFQGKKTKFASDDEHDEHDENGATGPVKRAREETDKEEPASKQQKTENGAGDQLast
1 -90.400[A] KOG4213 RNA-binding protein La  ali  100  1MAENGDNEKMAALEAKICHQIEYYFGDFNLPRDKFLKEQIKLDEGWVPLEIMIKFNRLNRLTTDFNVIVEALSKSKAELMEISEDKTKIRRSPSKPLPEVTDEYKNDVKNRSVYIKGFPTDATLDDIKEWLEDKGQVLNIQMRRTLHKAFKGSIFVVFDSIESAKKFVETPGQKYKETDLLILFKDDYFAKKNEERKQNKVEAKLRAKQEQEAKQKLEEDAEMKSLEEKIGCLLKFSGDLDDQTCREDLHILFSNHGEIKWIDFVRGAKEGIILFKEKAKEALGKAKDANNGNLQLRNKEVTWEVLEGEVEKEALKKIIEDQQESLNKWKSKGRRFKGKGKGNKAAQPGSGKGKVQFQGKKTKFASDDEHDEHDENGATGPVKRAREETDKEEPASKQQKTENGAGDQ 408
2 -48.700[R] KOG1855 Predicted RNA-binding protein  ali follow..  17  270.TLDPSLIPSEELAAEITDAVEFYFSNESILKDAFLLKHVRRNEGFVSLKLVSSFKRVRQLTREWKVVGDAVRRKSR-KIELNDVGTKVRRIEPLP------SFDETMPSRTIVACDLPLDLTIEKVSDLFSPCGEIALIRILKPGMAQQKECALVEYLESSSARDARHLNG-PFQVYEMVAPKKKTGKKAAVIQIAAPVARMVENYRYYNDANYERSRGGSFS........................................................................................................................................................................................ 501
3 -33.100[OJ] COG5193 La protein, small RNA-binding pol III transcript stabilizing protein and related La-motif-containing proteins involved in translation  ali follow..  34  322.........LCDVQAFLTSQLEYYFSIENLCKDMFLRKHMD-DEGYVPLAFLASFNRIKSFSTDLNLLHAACKASD--IIDVAIDSIKVRRKET.......................................................................................................................................................................................................................................................................................................................... 408
4 -25.300[T] KOG2591 c-Mpl binding protein, contains La domain  ali follow..  11  5..........VEVASKLNPNAKVWQEIAPGNTDATPVTHGTESWHEIAATSGAHPEGNAELSEDICKEYEVMYSSNTTGIEESTDGMILG----------------SHKRCIVILREIPETTPIEEVKGLFKSENCPKVISC----EFAHNSNWYITFQSDTDAQQAFKYLREEFQGKPIMARIKAI............................................................................................................................................................................................................................. 175
5 -19.800[A] KOG0106 Alternative splicing factor SRp55/B52/SRp75 (RRM superfamily)  ali follow..  11  4................................................................................................................VYIGRLPNRASDRDVEHFFRGYGKLSDVIMKN-------GFGFVDFQDQRDADDAVHDLNKELCGERVILE-------PRRKVGYNEERSGSGFRGREPTFRKGGERQFSNRYSRPCSTRFRLVIDNLSTRYSWQDIKDHIRKLGIEPTYSEAHKRNVAIVCFTSHDDLRDAMNK--------LQGEDLNGRKLKCTDETRDRSRSRSPRRRSRSRSPTRSRSPPARRRSPGSDRSDRKSRSASPKKRSDKRARSESKSRSRSGGRRSRSNSPPNRSPSPKKRRDNSSPRSGSAS. 280
6 -18.300[A] KOG4209 Splicing factor RNPS1, SR protein superfamily  ali follow..  14  1........................MSDDIIDDDVLNIEDMTGDD--------ADLSAIEGDLNEIEEEQKKLKAIQNEM---GHMNLNTSSQSNSSQSLLTPEEKAEADAKSVYVGNVDYGATAEEIEQHFHGCGSVSRVTIQCDRSGHPKGFAYVEFTEKEGMQNALAMTDSLLRGRQIKVDPKRT............................................................................................................................................................................................................................. 155
7 -18.200[A] KOG0146 RNA-binding protein ETR-3 (RRM superfamily)  ali follow..  13  1..................................................MYIKMATLAN--GQADNASLSTNG-----LGSSPGSAGHMNGLSHSPGNPSTIPMKDHDAIKLFIGQIPRNLDEKDLKPLFEEFGKIYELTVLKDRTGMHKGCAFLTYCERESALKAQSALHEQKTLPGMNRPIQVKPADSESRGGSSCLRQPPSQDRK---------------------------VGMLNKQQSEDDVRRLFEAFGNIEECTILRGPDGAFVKYSSHAEAQAAINALHGSQTMPGASSSLVVKFADTDKERT............................................................................................... 237
8 -17.500[AJ] KOG0123 Polyadenylate-binding protein (RRM superfamily)  ali follow..  14  87.SQRDPSLRKSGVGNVFIKNLDKSIDNKAL-YDTFVVCDENGSKGY-----FVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELG----------AKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVN--------------------YIKNLDDTIDDEKLRKEFSPFGSITSAKVMLEDGRGFVCFSSPEEATKAVTEM---NGRIVGSKPLYVALAQRKEERK............................................................................................... 375
9 -17.200[A] KOG4211 Splicing factor hnRNP-F and related RNA-binding proteins  ali follow..  13  25..................DEVQRFFSDCKIQNGAQGIRFIYTREGRPSGEAFVELE-------SEDEVKLALKKDRETMVEVFKSN---NVEMDWVLKHTGPNSPDTANDGFVRLRGLPFGCSKEEIVQFFSGLEIVPNITLPVDFQGRSTGEAFVQFASQEIAEKALKKHKERIGHRYIEIFKSSRAEVRTHYDPPRKLMAMQRPGPYDRPGAGSDHRYGDGGSTFQSTTGHCVHMRGLPYRATENDIYNFFSPLNRVHIEIGPDGRVTGDVEFATHEDAVAAMSKDKAN----MQHRYVELFLNSTAGASG............................................................................................... 369
10 -17.200[J] KOG0899 Mitochondrial/chloroplast ribosomal protein S19  ali follow..  12  1........................MESRHFATAL----VFLASKGF-----DILYWV---------------RFQASSMAFCTKLGGHWKQGVNVPVSSMLGS--LRYMSTKLYIGGLSPGTDEHSLKDAFSSFNGVTEARVMTNKTGRSRGYGFVNFISEDSANSAISAMN............................................................................................................................................................................................................................................ 125
11 -17.100[A] KOG0105 Alternative splicing factor ASF/SF2 (RRM superfamily)  ali follow..  12  5.....................................................................................................ADERGGEGDGRIYVGNLPTDVREKDLEDLFYKYGRIREIELKN--RHGLVPFAFVRFEDPRDAEDAIYGRNYDYGQCRLRV------------------------EFPRTYGGRGGWPRGGRNGPPTRRSDFRVLVSGLPPSGSWQDLKDHMREAGDVCYADVQK-DGVGMVEYLRKEDMEYALRKL---DDTKFRSHEGETSYIRVYPERSTSYGYSRSRSGSRGRDSPYQSRGSPHYFSPFR............................................................... 219
12 -16.900[A] KOG0128 RNA-binding protein SART3 (RRM superfamily)  ali follow..  15  581.AVQKAAPGTEDARTIFVSNLDFTTTEDEI-RQAIKANSDLVHRGF-----YVVME-------NDQKAQQALLKDRVPV-----KGRPMFISANDPEKRVGFKFSTTLEKSKVFVRNVHFQATDDELKALFSKFGTVTSVRRVTHKDGKPKGIAFVDFDTEASAQKCVASGDLMLRERELEVALSNPPVKKDKSHGKPAAIGASLEEDGPRKGHAA................................................................................................................................................................................................ 789
13 -16.500[A] KOG0124 Polypyrimidine tract-binding protein PUF60 (RRM superfamily)  ali follow..  10  1MATATIALQVNPAAAAAVVAAGDKWKSIKMENGQSTAAKLG---PPLTPEQQEALQKAKKYAMEQSIKSVLVKQTQLTNLQMAAVTMGFGDPLSPLQSMAAQRQRALAIMCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSTMKHKGFAFVEYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNR----------------------------VASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGFIEYEKAQSSQDAVSSM---NLFDLGGQYLRVGKAVTPPMPL............................................................................................... 309
14 -16.500[A] KOG4212 RNA-binding protein hnRNP-M  ali follow..  15  66.........................................................................................................NPTKRYRAFITNIPFDVKWQSLKDLVKEVGEVTYVELLMDAEGKSRGCAVVEFKMEESMKKAAEVLNHSLSGRPLKVKEDPDGEHARRAMQKVMATGPGMITIPPSILNNPNIPNEIIHALQAGRLGSTVFVANLDYKVGWKKLKEVFSMAGVVVRADILEDKDGGTVTFEQSIEAVQAISM----NGQLLFDRPMHVKMDERALPKG............................................................................................... 286
15 -16.300[R] KOG4454 RNA binding protein (RRM superfamily)  ali follow..  8  3....................................................................................................IKPTPSPPEERTIYVANFSEEVDEELLEELFIQAGPVVKVILRDVRDSN-AKFALVEFEDELSVLFAIELMNVRLFNQELQVKPRNGTNQEELYKRKKGEIEERVRSVAAPDRDGRRDSYRDDRNRNRNGNNRDSWQQQQPPRHHRQY---------------------------PLPPPPPPPLMGGSGGHWRSGGERGPPQYSTPQMLPHQHFVNQMMQQQINRSAPPYNGRHQNSTPHRHHDRHGYDRSSSRHHRNDDRRRSAHFLDIRKFQAPPTSWAFGNFQCFFWNLFSKITYLQEVGGA.. 282
16 -16.200[A] KOG0117 Heterogeneous nuclear ribonucleoprotein R (RRM superfamily)  ali follow..  9  4........................................NHKSGD-----LSGTQ-------KEAALRALVQRTGYSLVQENGQRKYGG-------PPPGWDAAPPERGCEIFIGKLPRDLFEDELIPLCEKIGKIYEMRMMMDFNGNNRGYAFVTFSNKVEAKNAIKQLNKTKKREEILSEMKKEYESHRAAAMARRKLLPGRIQLWGHGIAVDWAEPEVEVDEDTMSSVKILYVRNLMLSTSEEMIEKEFNNIKPGAVERVKKIRDYAFVHFSNREDAVEAMKAL---NGKVLDGSPIEVTLAKPVDKDSYVRYTRGTGGRGTMLQGE............................................................................. 326
17 -16.200[R] KOG0114 Predicted RNA-binding protein (RRM superfamily)  ali follow..  26  14.............................................................................................................NRLLYVRNLPYKITSDEMYDIFGKFGAIRQIRVGNTPET--RGTAFVVYEDIFDAKNACDHLS............................................................................................................................................................................................................................................ 74
18 -16.100[A] KOG1190 Polypyrimidine tract-binding protein  ali follow..  15  2...........................................DGIVPDIAVGTKRGSDELFSTCVTNGPFIMSSNSASAANGNDSKKFKGDSR----------SAGVPSRVIHIRKLPIDVTEGEVISLGLPFGKVTNLLMLKG-----KNQAFIEMNTEEAANTMVNYYTSV-RGQPIYIQFSNHKELKTDSSPNQARAQAALQAVNSVQSGNLALAASAGMAMAGQSPVLRIIVENLFYPVTLDVLHQIFSKFGTVLKIITKNNQFQALLQYADPVSAQHAKLS......................................................................................................................... 240
19 -16.100[A] KOG0107 Alternative splicing factor SRp20/9G8 (RRM superfamily)  ali follow..  15  3...............................................................................................................RVYVGNLDPRVTERELEDEFRSFGVIRSVWVARRP----PGYAFLDFEDSRDARDAIREVD............................................................................................................................................................................................................................................ 59
20 -16.000[A] KOG0144 RNA-binding protein CUGBP1/BRUNO (RRM superfamily)  ali follow..  13  30..................KDLRELFEEINVLRDRSQNPPQSKGCCFV------TFYT---------------KAALEAQNALHNMKVLPGMHHPIQMKPADSEKNNAVEDRKLFIGMISKKCTENDIRVMFSSFGQIEECRILRGPDGLSRGCAFVTFTTRAMAQTAIKAMHQAQTMEGCSSPMVVKFADTQKDKEQKRMAQQLQQQ......................................................................................................................................................................................................... 204
21 -15.900[R] KOG0125 Ataxin 2-binding protein (RRM superfamily)  ali follow..  8  71.....................................................................QSSNSPSTQNGSLTQTEGGAQTDGQQSQTQSSENSESKSTPKRLHVSNIPFRFRDPDLRQMFGQFGKILDVEIIFNERGS-KGFGFVTFENSADADRAREKLHTVVEGRKIEVNNATARVMTNKK...................................................................................................................................................................................................................... 195
22 -15.700[R] KOG0226 RNA-binding proteins  ali follow..  15  144....................................................QELLRTQALQSDIDKM-KKQTDPFKKKIKEQQAKKKFVRSGGGQVWEDPSLAEWDENDFRVFCGDLGNEVSDELLAKAFRKYPSFQKAKVVRESTNKSKGYGFVSFRDSEDYVRAMREMDGKYVGNRPIKLRKSAWKERNIDVIKQKRKQKKE........................................................................................................................................................................................................... 298
23 -15.700[R] KOG0118 FOG: RRM domain  ali follow..  11  84..................RELQELFSKLNPMAEEFVPPSLNKQGG-------GGFFTSAGSFFRNNGFAGTGNGGYGNENGGFRRKKSFGQGKRRMNARTSMAQREDVIRRTVYVSDLDQQVTEEQLAGLFVSCGQVVDCRICGDPNSV-LRFAFIEFTDEEGAMTALNLSGTMLGFYPVKVLPSKTAIAPVNPTFLPRTEDEREMCART---------------------------TNIDKKVTQSDVKIFFESFCGE---DYQHSTRIAFVEFVMAESAIAALN-----SGVVLGSLPIRVSPSKTPVRPR............................................................................................... 351
24 -15.600[AJ] KOG0148 Apoptosis-promoting RNA-binding protein TIA-1/TIAR (RRM superfamily)  ali follow..  10  15.........SRDVTEALILQL---FSQIGPCKNCKMIMDTAGNDPY-----FVEFHEHRHAAAALAAMNGRKIMGKEVKVNWATTPSSQKKDTS--------------NHFHVFVGDLSPQITTEDIKAAFAPFGRISDARVVKDMTGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTN----------------ATRKPPAPKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPDKGYSFVRFNSHESAAHAIVSV---NGTTIEGHVVKCYWGKETLDMI............................................................................................... 280
25 -15.500[AR] KOG1365 RNA-binding protein Fusilli, contains RRM domain  ali follow..  11  191..................HHVAQFFAGLDIVPGALCLSSEGRRNG----EVLVQFS-------SQESRDLALKRHRNFLIEVYKAGLD-EFMHVATGSSTEAMEFVSANAIIVRMRGLPYDCTDAQIRTFFEPLKLTDKILFITRTDGRPTGDAFVQFETEEDAQQGLLKHRQVIGQRYIELFK--------------STAAEVQQVVKRCNLINSSPAVANAVEAPEEKKKDCVRLRGLPYEATVQHIVTFLGDFAGVHMVYNNQGHPSGFIQMINEQAASACAAGVHNN-SVGKKKRYIEVFQASAEELNL............................................................................................... 474
26 -15.500[A] KOG0121 Nuclear cap-binding protein complex, subunit CBP20 (RRM superfamily)  ali follow..  18  20....................................................................................................SEQERSLRDSCTLYVGNLSFYTTEEQIHELFSRCGDVRVIVMGLDKKKTPCGFCFVEYYVRSEAEAAMRFVN............................................................................................................................................................................................................................................ 92
27 -15.400[A] KOG0108 mRNA cleavage and polyadenylation factor I complex, subunit RNA15  ali follow..  12  1........................................................................................................MSMTAGNVVFVGNIPYDVSEQQMTEIFNQVGPVKTFKLVLDPETSGKGYGFCEFFDSETTAMAVRKLNSELGPRKIRVEFPSNDPRRNQSYEYTERTDRYMEQQN....................................................................................................................................................................................................... 107
28 -15.400[A] KOG4207 Predicted splicing factor, SR protein superfamily  ali follow..  17  13.............................................................................................................MITLKVDNLTYRTSPDSLRRVFEKYGRVGDVYIPLEPTKAPRGFAFVRFHDRSDAQDAEAAMD............................................................................................................................................................................................................................................ 76
29 -15.400[R] KOG1457 RNA binding protein (contains RRM repeats)  ali follow..  13  83....................................................................................................VHELKTRPGVRTLFVSGLPVDIKPRELYLLFRPFKGYEGSLIKLTAR---QPVGFVIFDSRAGAEAAKNALNGIRFDPENPQTLRLEFAKANTKMAKSKLMATPNPSNA....................................................................................................................................................................................................... 188
30 -15.300[A] KOG0145 RNA-binding protein ELAV/HU (RRM superfamily)  ali follow..  10  60..................EEFRSLFGSCKLVRDK----ITGQSLGY-----FVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSS------------------ASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITVKFANNPSQKSSQGPVPPSACSPRFSPITIDGMTSLVGMNIPGHTGTGWCIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTGFVTMTNYDEAAMAIASL---NGYRLGDRVLQVSFKTNKAHKS............................................................................................... 380
31 -15.000[A] KOG4206 Spliceosomal protein snRNP-U1A/U2B  ali follow..  11  15.....QNLNERIKKEELKRSLYCLFSQGRILDVVALKTPKLRGQAWV------TFSEVTAAGHAVRQMQNFPFYDKPMRLQYAKAKSDCLAKAE-APSFQPSGQETMPPNNILFIQNLPHETTSMMLQLLFEQYPGFKEIRMIDAK----PGIAFVEYEDDVQASIAMQPLQ............................................................................................................................................................................................................................................ 215
32 -14.600[R] KOG0149 Predicted RNA-binding protein SEB4 (RRM superfamily)  ali follow..  13  1...............................................................................MAYQPVPGSGFHY--------LNSPFGDTTFTKVFVGGLAWETQSETLRQHFEQYGEILEAVVIADKNGRSKGYGFVTFRDPEAARRACADPTPIIDGRRANCNLASLGRPRPPLPYAV.................................................................................................................................................................................................................. 112
33 -14.500[K] KOG1548 Transcription elongation factor TAT-SF1  ali follow..  15  73.........................................................................HTKRLYESTSAEGYPSGSRNKKSKSENSEASPAPVINKAVYIQGLPLDVTVDEIEEVFKKCGVIAKIKIYRTEDGTPKGDALIVFFRSESVELAEQLFDDTEFRYGSGQKMRVQKANIDYKKEKTVNKDVGGALKKKALRLRQQQMQQISSWDDVDEEVDDKRKKRFNKIDLKDDITEEAEKCGRVTNVVLYDKEPDGTVRFSNNEEAEACVRLM---QGRYFDGRVVEASIYDGKVRFQKSGKHTLDDEEDEEKRLEK............................................................................ 358
34 -14.200[A] KOG0115 RNA-binding protein p54nrb (RRM superfamily)  ali follow..  11  97.AFTESQLMDEVPKKKFTGRCRLFVG--NLPNETELKELFSPGKGF-----FLRLDTRAHAESAKEAIDGRIIHGRQVRVRFAVHGA------------------------AIRVKELSPTVSNEMLYHAFSHFGDVERAVHIVDEKGRPTGEGIVEFERKPNCNEAMAAIRDK.......................................................................................................................................................................................................................................... 252
35 -14.200[A] KOG0120 Splicing factor U2AF, large subunit (RRM superfamily)  ali follow..  11  81.VPVVGSTITRQARRLYVGNIPFGVTEEEMMESPVLACQINLDKNF-----FLEFR-------SIDETTQAMAFDG---INLKGQSLKIRRPHDYQPMPGITDTPAIKSPHKIFIGGLPNYLNDDQVKELLLSFGKLRAFNLVKDATGLSKGYAFCEYVDLSITDQSIAGLNGMQLGDKKLIVQRASVGAKNAQNAANTTQSVMLQVPGLSNVVTSGPPTEVLCLLNMVTPDELR--DEEEYEDILEDIKEECTKYGVVRSVEIPRPIEGVFVEFNSVLDCQKAQQA----TGRKFSDRVVVTSYFDPDKYHR............................................................................................... 413
36 -14.100[R] KOG0130 RNA-binding protein RBM8/Tsunagi (RRM superfamily)  ali follow..  20  68.........................................................................................................RSVEGWILFVTSIHEEAQEDEIQEKFCDYGEIKNIHLNLDRRGFSKGYALVEYETHKQALAAKEALN............................................................................................................................................................................................................................................ 135
37 -13.700[R] KOG0110 RNA-binding protein (RRM superfamily)  ali follow..  11  238.PKAKADKSNLELFTIKIHNVPYNTKRQEV-LKFF--RLPSKVHGF-----YVGFKTEKDMAKGMLKNKSFIKGKQVFFSDFTEKNKDAGNAKWKHQQDSLSKEDDISESGRIFFRNLAYTTTEEDLRKLFEQFGPVVEVNLPLDKTRKIKGFGTVTYMMPEHALKAFNTLDGTDFHGRLLHLLPSKDIEKNPKEDLDENDASLSFKEKKALKLKKNAQKDAFDEPAKKRSNTVILAKNLPAATEISEITPIFSRFGPIGRIVLPPSGVTALIEYCDPLEARQAFKK----AYSKFKNAPLYLEWAPEQVFTKTLSGEPVIPKSEPKPKEEVKPEEKPIVNDAKPDEEDSRAEDADDEPEPNTT............................................ 680
38 -13.600[J] KOG0122 Translation initiation factor 3, subunit g (eIF-3g)  ali follow..  20  207........................................................................................................RRRNDENSVRVTNLSEDTREPDLMELFHPFGAVTRVYVAIDQKGVSRGFGFVNFVSREDAQRAINKLN............................................................................................................................................................................................................................................ 275
39 -13.400[R] KOG4733 FOG: RRM domain  ali follow..  15  43.SSNNNSSSSSNSGWDQLSKTNLYIR--GLPTDQDLVKLCQPYGKIVSTKAILDFVDFD----SPAAAQKAVSALKASGVQAQ--------------------KQQEQDPTNLYISNLPLSMDEQELENMLKPFGQVISTRILRDSSGTSRGVGFARMESTEKCEAVIGHFNGKFIKTPPGVSAPTEPLLCKFADGGQKKRQNPN........................................................................................................................................................................................................... 235
40 -13.200[R] KOG4307 RNA binding protein RBM12/SWAN  ali follow..  13  450.....TRLPTDLLRPAALE----AFIHPTAPLTLSSVKTVFGPGG-IHMHTIIRLDS-TMMRRNGEQGIK-IQQSDKKSFDTAIDGIPIPSVSMVPSKEQRSHEDDDKKSRRVQVTNVPFRMKDEELLEWFSEKVRPAKLTRTFYSDGNASDRWVAEFSSESLMKRSFGI-RTLCTGRTLRLRYIDNAKADEILKIEDVYGEGKRQMNEEARLQHEVAEKANPPS....................................................................................................................................................................................... 719
41 -13.100[A] KOG0131 Splicing factor 3b, subunit 4  ali follow..  14  30..........GGLDAQLSEELWELFVNVYVPKDR----VTNLHQNY-----FIEYR-------SEEDADYAIKVLNMIKL----HGKPIR------VNKASQDKKSLDVGANLFIGNLDPDVDEKLLYDTFSAFGVIASNPMRDPDTGNSRGFGFISYDSFEASDAAIESMTGQYLSNRQITVSYAYKKDTKGERHGTPAER.............................................................................................................................................................................................................. 205
42 -12.600[K] KOG0147 Transcriptional coactivator CAPER (RRM superfamily)  ali follow..  17  156...........QLAARIRPRLEDFFSDVRIISDR----NSRRSKGI-----YVEFC-------EIQSVPLAIGLTGQRLIIVQASQAEKNRLAAMA----NNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDGRSKGYGFITFSDSECARRALEQLN............................................................................................................................................................................................................................................ 309
43 -12.600[R] COG0724 RNA-binding proteins (RRM domain)  ali follow..  17  186.........................................................................................................ERDDMCTLKIMQVNENADENSLRELLFPFAPIPRVSVVRNKEGKSRGLAFVTFSSEEVAEQALRFLD............................................................................................................................................................................................................................................ 254
44 -12.500[D] KOG2186 Cell growth-regulating nucleolar protein  ali follow..  21  403.........................................................................................................RDIAQRNIFVRGFGWDTTQENLKTAFESYGEIEECSVVMDKTGRGKGYGFVMFKTRKGAREALKRPEKRMYNRIV.................................................................................................................................................................................................................................... 478
45 -12.500[R] KOG0126 Predicted RNA-binding protein (RRM superfamily)  ali follow..  11  6................................................................................KVKLINELNEREVQLGVADKVSWHSEYKDSAWIFLGGLPYELTEGDIICVFSQYGEIVNINLVRDKKGKSKGFCFLCYEDQRSTILAVDNFNIKIKGRTIRVDHVSNYRAPKDSEEIDDVTRQLQEKGCGARTPSPSLSESSEDEKPTKKHKKDKKEKKKKKKEKEKADREVQAEQPSSSSPRRKTVKEKDDTGPKKHSSKNSERAQKSEPREGQKLPKSRTAYSGGAEDLERELKKEKPKHEHKSSSRREAREEKTRIRDRGRLQMHILAGIMGVLKGVVIEVEVGAEINPIGIKGPDAPGRGVLRIPVTVGVTEDFSCTVD..... 330
46 -12.200[K] KOG4210 Nuclear localization sequence binding protein  ali follow..  12  139..................DDLVRFFIAKTKDNEDEKSRVTEQDITRLSMPRVAAKNSNAMKNKGFCYMFFKNVEQMKAVLELSENGRNMLNYSGRPDKDDLVAMSKNPPSRILFVGNLSFDVTDDLLRKHFQHCGDIVKIRMATFEDSKCKGFAFIDFKNEEGSTNELKDKS............................................................................................................................................................................................................................................ 301
47 -12.100[A] KOG4205 RNA-binding protein musashi/mRNA cleavage and polyadenylation factor I complex, subunit HRP1  ali follow..  13  1.........................................................MTTTVSTGATAVATLRETSPPV-----DGHEEARLNADS----DDGSHGSQDPGKMFIGGLSWQTTAENLRDYFGRFGEVNECMVMRDPAKRARGFGFITFVDPSSVDKVLNNREHELDGKKIDPKVAFPKRTQAKLVTKTKK----------------------------------VFIGGLSATSTLEDMKQYFETYGKVEDAMLMFDKATGFVTFDSDEVADKVCEIHFHE----INGKMVECKKAQPKEVML............................................................................................... 216
48 -12.000[R] KOG4208 Nucleolar RNA-binding protein NIFK  ali follow..  19  2.........................................................................................................AAFSRSAGPILSLN--QEDAELQKEVAQCDTVTRFRLSRKKRTNSKGYAFVEFESEDVAKIVTETMN............................................................................................................................................................................................................................................ 68
49 -11.400[R] KOG0153 Predicted RNA-binding protein (RRM superfamily)  ali follow..  17  225.........................................................................................................EDRNITTLYVGNLPEEITEPELRDQFYQFGEIRSIALVPR-----QQCAFVQYTKRNAAELAAERTFNK.......................................................................................................................................................................................................................................... 288
50 -11.300[A] KOG2202 U2 snRNP splicing factor, small subunit, and related proteins  ali follow..  10  79........................................................................................................................EDFFEDLFEELGKFGEIESLNICDNLADHMIGNVYVQFKEEDQAAAALQALQGRFYSGRPIIADFSPVTDFREATCRQYEENNCNRGGYCNFMHVKLVSRELRRKLFG------------------------------------------------------------------------------RYRRSYRRGSRSRSRSRSISPRNKRDNDRRDPSHREFSHRDRDREFYRHGSGKRSSERSERQERDGSRGRRQASPKRGGSPGGGREGSEERRARIEQWNRER 288
51 -11.200[D] KOG4660 Protein Mei2, essential for commitment to meiosis, and related proteins  ali follow..  9  66.SPNLNKLVIGNSEKDSLEDVE-ALEILLPEDENELLPGLIDELNFTGLPDELDFCTGGGMELDVESQDNHAVDASGMQISDRGNAFVPRKRPNTAGRVSVEHPNGEHPSRTLFVRNINSSVEDSELSALFEPFGEIRSLYTACKS----RGFVMISYYDIRAAHAAMRALQNTLLRKRTLDIHFSIPKENPSEKDMNQGT----------------------------------VIFNVDTTVSNDELLQLFGAYGEIREIETPNRRFHRFIEYYDVRDAETALKAL---NRSEIGGKCIKLELSRPGGARR............................................................................................... 348
52 -10.300[R] KOG2135 Proteins containing the RNA recognition motif  ali follow..  10  361.........................................................................................................INRDNCTLQVAKIPPEMTIAKLNEHFATFGTVDNIQVRYNGE---IDSALVTYASKFDAGKAYKSPTPVLNNRFIKVFWHNPGGEGSENATGKPSSPTSPPKPVEKPKIATVQESKFVSVAAQNYRKQIQDAKERLTKEKSILSTLVQAQNQHNIILDKWMVKQKELLIKARTSTDETDKKNATKL----VKHLHKKIKACKEEVDGILLKISEKSMVVDEIAAQIEELKNPQKSDDSTRKRKAGSDGDEPQSKMSSVVIVRGVTDELVTDLMAGEVFDHSVKADDDGLITAVFPFRKTGDAL 662
53 -10.200[R] KOG1995 Conserved Zn-finger protein  ali follow..  15  275.........................................................................................................DNCDNARIYISNLPPDVTTDELKDLFGGIGQVGNIKIYTDEKGNYKGDACLAYEDPSAAHSAGGFFNYEMRGNKISVTMAEKSAPRAPTFDQSFIILVGNMS......................................................................................................................................................................................................... 391
54 -9.810[K] KOG2068 MOT2 transcription factor  ali follow..  14  13.................AEEMD--LTDQQL---VWCWHHIMDMAE--------RCPACRTPYDKEKIVGMTVDQERLASEGNMDRKKIQKSKPKSSDGRKPLTSVRVVQRNLVYIVGLPLNLADEDLKEYFGQYGKVLKVSMSRTATGL-TCSVYITYGKEEEAIRCIQSVH............................................................................................................................................................................................................................................ 179
55 -9.760[J] KOG0129 Predicted RNA-binding protein (RRM superfamily)  ali follow..  11  442.FSHQNGERVERYSRKV-DEITASFRRFGPLIVDWPHKSYFPPKGY-----FLLFQDESSVQ---ALIDACIEEDGKLYLCVSSPTIKDKPVQIRPWNLSDSDFVMD-PRKTIFVGGVPRPLRAVELAMIMDRYGGVCYAGIDTDPELKYKGAGRVAFSNQQSYIAAISARFVQLQHGEIDKRVEVK............................................................................................................................................................................................................................. 641
56 -9.260[T] KOG0116 RasGAP SH3 binding protein rasputin, contains NTF2 and RRM domains  ali follow..  16  267....................................................................................................AATIDQQAEGYTIFVANLLMDATPEQLNETFKGFGAITKDGIQRSYRLKGNCFGFVTFASAEAVKLVLQAHKES.......................................................................................................................................................................................................................................... 341
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Ye Y, Godzik A. Multiple flexible structure alignment using partial order graphs. Bioinformatics. 2005 Mar 3;