current user: public
If you have questions about the server, please let us know.

Query: [K] KOG4218 Nuclear hormone receptor betaFTZ-F1, from COG1018

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
    .   10    .   20    .   30    .   40    .   50    .   60    .   70    .   80    .   90    .  100    .  110    .  120    .  130    .  140    .  150    .  160    .  170    .  180    .  190    .  200    .  210    .  220    .  230    .  240    .  250    .  260    .  270    .  280    .  290    .  300    .  310    .  320    .  330    .  340    .  350    .  360    .  370    .  380    .  390    .  400    .  410    .  420    .  430    .  440    .  450    .  460    .  470    .  480    .  490    .
# Score Template Links and tools%idFirst MSSNSDTGDLQESLKHGLTPIVSQFKMVNYSYDEDLEELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKRYTCIENQNCQIDKTQRKRCPYCRFQKCLSVGMKLEAVRADRMRGGRNKFGPMYKRDRALKQQKKALIRANGLKLEAMSQVIQAMPSDLTISSAIQNIHSASKGLPLNHAALPPTDYDRSPFVTSPISMTMPPHGSLQGYQTYGHFPSRAIKSEYPDPYTSSPESIMGYSYMDSYQTSSPASIPHLILELLKCEPDEPQVQAKIMAYLQQEQANRSKHEKLSTFGLMCKMADQTLFSIVEWARSSIFFRELKVDDQMKLLQNCWSELLILDHIYRQVVHGKEGSIFLVTGQQVDYSIIASQAGATLNNLMSHAQELVAKLRSLQFDQREFVCLKFLVLFSLDVKNLENFQLVEGVQEQVNAALLDYTMCNYPQQTEKFGQLLLRLPEIRAISMQAEEYLYYKHLNGDVPYNNLLIEMLHAKRALast
1 -156.000[K] KOG4218 Nuclear hormone receptor betaFTZ-F1  ali  100  1MSSNSDTGDLQESLKHGLTPIVSQFKMVNYSYDEDLEELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKRYTCIENQNCQIDKTQRKRCPYCRFQKCLSVGMKLEAVRADRMRGGRNKFGPMYKRDRALKQQKKALIRANGLKLEAMSQVIQAMPSDLTISSAIQNIHSASKGLPLNHAALPPTDYDRSPFVTSPISMTMPPHGSLQGYQTYGHFPSRAIKSEYPDPYTSSPESIMGYSYMDSYQTSSPASIPHLILELLKCEPDEPQVQAKIMAYLQQEQANRSKHEKLSTFGLMCKMADQTLFSIVEWARSSIFFRELKVDDQMKLLQNCWSELLILDHIYRQVVHGKEGSIFLVTGQQVDYSIIASQAGATLNNLMSHAQELVAKLRSLQFDQREFVCLKFLVLFSLDVKNLENFQLVEGVQEQVNAALLDYTMCNYPQQTEKFGQLLLRLPEIRAISMQAEEYLYYKHLNGDVPYNNLLIEMLHAKRA 495
2 -123.000[K] KOG4216 Steroid hormone nuclear receptor  ali follow..  20  60.QLEHINWDGATAKNFINLREFFSFLLPALRKAQIEIIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQKCLAVGMSRDAVKFGRMSKKQRDSLYAEVQKHRMQQQQRDHQQQPGEAEPLTPTYNISANGLTELHDDLSNYIDGHTPEGSKADSAVSSFYLDI---------QPSPDQSGLDINGIKPEPICDYTPASGFFPYCSFTNGETSPTVSMAELEHLAQNISKSHLETCQYLREELQQITWQTFLQEEIENYQNKQREVMWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMCRAF---DSQNNTVYFDGKYASPDVFKSL---GCEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQQKIQLALQHVLQKNHRE-DGILTKLICKVSTLRALCGRHTEKLMAFKAIYPDIFPPLYKELFTSEFE 541
3 -117.000[K] KOG4215 Hepatocyte nuclear factor 4 and similar steroid hormone receptors  ali follow..  28  13.AYTTLEFENVQVLTMGNDTSPSEGTNLNAPNSLGVSALCAICGDRATGKHYGASSCDGCKGFFRRSVRKNHMYSCRFSRQCVVDKDKRNQCRYCRLKKCFRAGMKKEAVQNERDRISTRRSSYEDSSLPSINALLQAEVLSRQITSPVSGINGDI------------------------------------------------------------------------------------------------------------------------------------RAKKIASIADVCESMKEQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMVFK--DVLLLGNDYIVPRHCPELAEM--SRVSIRILDELVLPFQELQIDDNEYAYLKAIIFFDPDAKGLSDPGKIKRLRSQVQVSLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFIKLFGMAKIDNLLQEMLLGGSP 370
4 -115.000[T] KOG3575 FOG: Hormone receptors  ali follow..  19  2.....SPLKMHVNMLQSDHALIMSSFPEPSPSSKRPTENCKVCGDRPNNDRYGASACLGCTVFFRRAVVKNLKYKCMKEQNCLISCTYRNACRYCRFQKCFAVGMHSSAIQRRDLVGPRKISGDGEVIICENNTFLDDFASFQRTQFAEHLQYFTEHQVDVAFHVDQANVVKF---------------------------------------------------------------------------------------------------------------------RRRARAHDVNVMLKLCLKQATEWANRLKLFKSLPAESKRSILAEYCLAFNLIDQGYKTSKEADLGIWLLQNGSFMHPDYFFGLNVTSVDEVAEMINCLSTPFRRLEIDEVECAALKVILLLTPSCSKRGREGVLAGLYTNCTEELMDHCMRKFPENAVRFGEILLLLSGIRCGIKTMYNQTRVSDLFNFMKFDNSVKILIILSGR 392
5 -99.700[T] KOG4846 Nuclear receptor  ali follow..  18  113.QASVSSPATSVTSSLSPPDSLSNGHTTQRHHIGKAISFCKVCGDKASGYHYGVTSCEGCKGFFRRSIQRKIDYRCLKQQVCEIKRESRNRCQYCRFKKCLDSGMSKDSVRQMKFRNAMRDDKSPDSVFVPEISTLERQEEVDAVYEAVLRAHTTFSFY------------------------------------------------------------------------------------------------------------TDIKIRSIVARPFNVRINEDSKMNRLNAWQIYAHEIDVDIKEVVNFVKEIPKFNFINGNDKAVLLRKNAFPLYLLRIVRGM----SNRGLMLRDGRLIDFKSLQL----LYGSLADEMLAFANHIITIGCTDGDIALFIVLILCQPL-TTEQQFSTNFKSQLQLLEMFDFYKKTCRIDGCDTYKQLMKCIHELNRLNELHKQQLNILRENSFLNLPPLVVEMFQLST. 495
6 -86.600[K] KOG4217 Nuclear receptors of the nerve growth factor-induced protein B type  ali follow..  24  254.LAFPPLGLTPSPTASSLLGESPSLPSPPSRSSSSGEGTCAVCGDNAACQHYGVRTCEGCKGFFKRTVQKNAKYVCLANKNCPVDKRRRNRCQYCRFQKCLSVGMVKEVVRTDSLKGRRGRLPSKPKSPLQQEPSQPSPPSPPICMMNALVRALTDSTPRDLDYSRYCPTDQAAAGT------------------------------------------------------------------------------------------------------------------DAEHVQQFYNLLTASIDVSRSWAERIPGFTDLPKEDQTLLIESAFLELFVLRLSIRSNT--AEDKFVFCNGLVLHRLQCLR----GFGEWLDSIKDFSLNLQSLNLDIQALACLSALSMITER-HGLKEPKRVEELCNKITSSLKDHQSKGQALEP-NESKVLVALVELRKICTLGLQRIFYLKLEDLVSPPSIIDKLFLDT.. 623
7 -16.600[O] KOG4275 Predicted E3 ubiquitin ligase  ali follow..  12  1.....................................MPCESC-----GVEFTVFRCFDCKRYY-----------C---ANC----IASRRCKRCSVEGCLEKEELVGLVLTHVAQVDRSRGSNASSNSPGRGQANPIDSLKQSCQNFFSNLSDNISDSLASFDSKVTTKPPESRQPEVPTHIFEQPRVSTREIPTYASAVNGGPQHVHVQQQATTTNGGSQSSSSPSTSTQSSNNRDASSSSQAHVAHQEARNEEQ.............................................................................................................................................................................................................................................. 231
8 -16.100[O] KOG1645 RING-finger-containing E3 ubiquitin ligase  ali follow..  2  67.TREYIDVLDSPVRVSQNESEGIENQNRRMSNGNKVTLRDCLVLSVWKFGP---VANTKSGILDSIV--------F-------PVDASTSGFSSDE-VEGSLRDVRKDDEAHKRILFLEAKLRSIEQKTASWSNKEVQWKITEAELRLEVTKLKKKIANMESTTKGSQSQSNVASQEKYIPAHNIYQEHHGQ............................................................................................................................................................................................................................................................................................................... 254
9 -15.700[R] KOG4299 PHD Zn-finger protein  ali follow..  17  228.LGNESENFNDMEGRAEDISSNELLPTPEEYPYRYNNDYCSACHG--PG----FLCCETCPNSFH--------FTCID----PIEEKN---CNECKHHS............................................................................................................................................................................................................................................................................................................................................................................................................ 313
10 -15.200[K] KOG3815 Transcription factor Doublesex  ali follow..  11  1MNGYGSPYLYMGGPVSQPPRAPLQRTPK-----------CARCRN-----H-GVLS----KGH-KR---------CR--KDC--------TCEKCILQRVMQVALRRQQANESLESLIPDSLRALPGPPPPGDAVAAPQPPPASQPSQPQPPRPAAELAAAAALRWTAEPQPGALQAQLAKPDLTEERLGDGKSADNTEVFSDKDTDQ............................................................................................................................................................................................................................................................................................... 177
11 -15.100[R] KOG4323 Polycomb-like PHD Zn-finger protein  ali follow..  14  154FHVEGMKTKSGRKIQRPVAYNPNATALKRKSRKVDMVTLCSVCQRGHSPLSNRIVFCDGCNSPYHQL--------CIDDATVQDVDAE---CMKCQYRR............................................................................................................................................................................................................................................................................................................................................................................................................ 247
12 -14.900[R] KOG3002 Zn finger protein  ali follow..  18  1MAPGGSALKEALESNSTGVDYEVKMAKVEANSKPTKSGSCPVCTN-PNG-H---TLCSSCRCLALEKVAESLEVPCRQNLGCQDILKHEQHCRFCPYAECSVTGDIPTLVDH............................................................................................................................................................................................................................................................................................................................................................................................... 164
13 -14.900[K] COG5641 GATA Zn-finger-containing transcription factor  ali follow..  9  93.PDTNSLHHILPKNQVKNNGQTMDANCNNNVSNDANVPVCKNCLTSTT----GAMLCNAC-GFLK------------------LHGKPR-------------ISLKTDVIKSNRKSNTNHAHNLDNFRNQTLIAELKGDCNIESSGRKANRVTSEDKKKKSSQLLMGTSSTAKISKKPKTESKERSDSHLSATKLEVLMSGDCSRPN................................................................................................................................................................................................................................................................................................ 273
14 -14.800[O] KOG0320 Predicted E3 ubiquitin ligase  ali follow..  17  228.ILPRRSAENDPVVDLDVASPPKRVNRDIDESQKEELYKCPICMDSVSKREPVSTKC----GVF-----------C---REC-IETRATHKCPICNKK------LTARQF................................................................................................................................................................................................................................................................................................................................................................................................. 314
15 -14.600[K] KOG4577 Transcription factor LIM3, contains LIM and HOX domains  ali follow..  18  3............QSATVPAEGAVKGLPEMLGVPMQQIPQCAGCNQHILDWHSSCLKCADCQRCFSR---AGSVY-CKEDTACAQDFVYHLHCFAC--IICLATGDEFYLMEDGRL............................................................................................................................................................................................................................................................................................................................................................................................ 138
16 -14.600[S] KOG4317 Predicted Zn-finger protein  ali follow..  11  3...............PEKTIISSESSNSSPLNPSSTRIICHVCNKQFS--QY---TCPRC----------NFRY-C--SLPC---KSHSVQCTESFMRDNVNDELKQVRSDDQTKRKMLEILKRFHEEEEEDDGGIDSITDDEGLSLPEEIIQKIMNGDEVSLDDLSLEERKGFQRALASGELSKMIQPWDPWWLLASARTINLGLGGTQLVQCVEDEEETTVVSEIPRGPDTPLISLSKLTSTNPSPL----------------------------------------------------LPIHLIDIAYSYCFTLRIYN----GEWQSDSLGAATMVLTVSSVLGHNGQPETIKEVLSF-----LEQTCSSAYKNLGGGLKFGLNLVDDVICF-LSLGSGAMVCLLGLILGAIKEVKSSSGRDLKKKLAERKVFYMMCWVNEQNSEVWEALEPSVRAEKNSVVELNDYRGFPEMKKKDQFRVVIEEI...... 405
17 -14.600[R] COG5048 FOG: Zn-finger  ali follow..  15  514.EINTYTTNSPSKITRKLTTLPRGSIDKYVKEMPDKTFECLFCTKTFK-THLE-YSCDGCKAFVRNHSHQEKAYAC----PCALVVHRSRENVVIK-SSPIKENINKDQLRRERSYDGNG....................................................................................................................................................................................................................................................................................................................................................................................... 696
18 -14.500[O] KOG4265 Predicted E3 ubiquitin ligase  ali follow..  23  255................GIENKNNQETKPSDDENSDNSNECVVCLSDLRD----ILPCR-C--------------LC---TSCA--RYQANNCPICRPGPPADPGGAEEARS................................................................................................................................................................................................................................................................................................................................................................................................ 334
19 -14.200[T] KOG4825 Component of synaptic membrane glycine-, glutamate- and thienylcyclohexylpiperidine-binding glycoprotein (43kDa)  ali follow..  15  716.VQEKESDAVKPKNQDIQGGKAAPAEALGIPDEHYLDNLCIFCGEEGLDLHY-LTRCDHCKQVVE-SLTEHLLTECDKKDGCYVFKEEHKDCNRCPL--C-EEAWKAHLMGPAGCTMNLRKTHILQKAPALQPGKSSAVAASGPLGSKAGSKIPTPKGGLSKSSSRTYAK..................................................................................................................................................................................................................................................................................................................................... 924
20 -14.100[K] KOG1244 Predicted transcription factor Requiem/NEURO-D4  ali follow..  19  235.EEEGEDKEDSQPPTPVSQRSEEQKSKKGPDGLALPNNYCDFC-NKKTGQPEELVSCSDCRSGHPSCLQKTYRWQCIECKCCNICGTSENDCDDC--MYCLTPSMSE.................................................................................................................................................................................................................................................................................................................................................................................................... 363
21 -14.000[R] KOG4602 Nanos and related proteins  ali follow..  19  195.SRGQRLETQEIEEPSPGPPLGQDQGLGAPGANGGLGTLCNFC--KHNGEH-GVVVCP----ILRH-------YVCP----CGATGDQAHTLKYCPLNG----GQQSLYRRSGRNSAGRRVK..................................................................................................................................................................................................................................................................................................................................................................................... 307
22 -13.900[O] KOG0823 Predicted E3 ubiquitin ligase  ali follow..  18  78.IHERSRERLVENGENKTYLIAKALNMEKTSSVPGGFFDCNICLEKAE-----ILTC--CGHLF-----------C----GCFYQYLNIKECPVCD-AEVIPIGDDCDGTKPKLEDCGIS....................................................................................................................................................................................................................................................................................................................................................................................... 188
23 -13.700[R] KOG0490 Transcription factor, contains HOX domain  ali follow..  23  5.......................................CAGCERPILDWHIKCVQCCECKTNLSEKSREGKLY-CKNDAGCARSKVFHLNCFTC--MVCLSTGEELYVIDENKF............................................................................................................................................................................................................................................................................................................................................................................................ 113
24 -13.600[O] KOG3579 Predicted E3 ubiquitin ligase  ali follow..  15  441.RLGPREVGGQGAGNTGGLEPVHPASLPDSSLATSAPLCCTLCHERLEDTHF--VQCPSC--F-RQSIKQQ-VY-CPSGEKCPLV----SNVPWAFMQGEIATILAGDVVKKER............................................................................................................................................................................................................................................................................................................................................................................................. 558
25 -13.500[OU] COG5082 Arginine methyltransferase-interacting protein, contains RING Zn-finger  ali follow..  12  49.........................SDDDKDAIKEAAPKCNNCSQ--RG-HLK-IQCSKCVGHYRSQCPHKWK-QCT---LCKSKKHSKERCPYC---NCGGKGHFGDDCKEKRSSRVPNEDGSAFTGSNLSVELKQEYYRHMNRNSDENEDYQFSESIYDEDPLPRPSHKRHSQNDHSHSGRNKRRASNFHPPPYQKSNVIQPTIRGETLSLNNNISKNSRYQNTKVNVSSISENMYGSRYNPSTYVDNNSIS................................................................................................................................................................................................................................................. 321
26 -13.200[O] KOG1571 Predicted E3 ubiquitin ligase  ali follow..  17  261..........EAKIRERLDTERRERRARSRPHTLSQDQLCVVCSTNPKG-H--VCLCEDCA------------------------QKISVTCPVCRIVSKAAAFIA..................................................................................................................................................................................................................................................................................................................................................................................................... 338
27 -13.000[K] KOG2494 C3H1-type Zn-finger protein  ali follow..  10  139.GMGLVPAELVPNTPVLIPGNPPLAMPGAVGPKLMRSDKLEVCREFQRG------NCNDCR--YAHEASDNTVTICMIKGRC-----SREKCKYFHPPAHLQARLKAAHHQMNHSAASAMALQPGTLQLIPKRSALEKPNGATPVFNPTVFHCQQALTNLQLPQPAFIPAGPILCMAPASNIVPMMHGATPTTVSAATTPATSVPFAAPTTGNQLK....................................................................................................................................................................................................................................................................................... 353
28 -12.600[O] KOG1100 Predicted E3 ubiquitin ligase  ali follow..  19  249.DAQSCCGSNDEGDSEEERWKLAGEAQDTKKMCRVGMSMCRSCGKGEASV---LLPCR-C--------------LC---SVC---GSSLNTCPICKKTASLHVNLSS.................................................................................................................................................................................................................................................................................................................................................................................................... 335
29 -12.500[O] KOG2813 Predicted molecular chaperone, contains DnaJ domain  ali follow..  24  210.....................................VVCPTCGEPGFYKENQMMKCSTCYGRGLVAHKDGSDTICT---NC--NGKGKLPCPTCQ-QTCDSTGSLLTSSI................................................................................................................................................................................................................................................................................................................................................................................................ 287
30 -12.500[TZR] KOG1704 FOG: LIM domain  ali follow..  12  205.......................................CAQCNDVLADQKYNKPVCLKC---FHSSSST---FSC---TTC-MSQGDLHCCCVCSSRVC-CGGEDEELLDEDRLGSPHRKVTQKSTKVVRIPASPRVAPRHPHVIQQNLTTTMTIQKPSVVIQNQRPKPPQRAPPPPPSENIYETVLPCSSNNSPNFDKKYSHELPTSPNHHNYYSKTPNNLLTGYPEMDGYSTSSSSDSDDEQLYISNIMAAASLSRVPAKSSSRKSKKNEPMMMSGGGVRMAKKKKSSR........................................................................................................................................................................................................... 485
31 -12.500[O] KOG0801 Predicted E3 ubiquitin ligase  ali follow..  17  146.PICSKSVASDEMEMHFIMCLSKPRLSYNDDVLTKDAGECVICGDTIA-----------CLCIYHK--------------SC-IDSEVNRSCPEHPAD............................................................................................................................................................................................................................................................................................................................................................................................................. 227
32 -12.300[R] KOG1595 CCCH-type Zn-finger protein  ali follow..  11  241....................PGENARRRDPRKYPYTCVPCP-CGD----------SCEYAHGVFESWLHPAQ-YRCKDETGC-----ARRVCFFAHRRDELRPVNASTGSAMVSPRSSNQSPEMSVMSPLTLGSSPMNSPMANGVPLSPRNGGLWQNRVNSLTPPPLQLNGSRLKSTLSARDMDMEMELRFRGLDNRRLGDLKPSNLEETFGSYDSASVMQLQSPSRHSQMNHYPSSPVRQPPPHGFESSAAMAAAVMNARSSAFAKRSLSFKPAPVASNVSDWGSPNGKLEWGMQRDELNKLRRSASF-VSWVNSL---NGAASRDKFKL--PSWAEQMYIDHEQ..................................................................................................................................................... 593
33 -12.200[T] COG5432 RING-finger-containing E3 ubiquitin ligase  ali follow..  9  24...................................TLLRCHICKDFLK-----LTPCG--HTF------------C---SLC-IRTNNQPNCPLCLLRSEFLVSEIIQSYTSLRSSLLDALRIPKPTPVPENEEVPGPENSSWIELISESESDSVNAADDDLQIVATSERKLAKRSMTDILPLSSKPSKRNFAMFRSERIKKKSKPNEQMAQCPICQQFYPLKALEKTHLDECLTLQSLGKKPKISTTFPTESNPHNKSSSRFKVRTPEVDKSSCGETSHVDKYLNSMMSAEHQRLPKITSMTQSQIKQKLS---------GLSTNGTRQNMIKRYNHYEML----------------------WNSNFCDSLEPVDEAELKRQLLSWDVSHNKTPQNSSNKGGISKLMIMKSNGKSSSYRKLLENFKNDKFNR-KGWMVMF----RKDFARL---IREAKM................................. 404
34 -12.200[L] KOG0287 Postreplication repair protein RAD18  ali follow..  9  24...................................TLLRCHICKDFLK-----LTPCG--HTF------------C---SLC-IRTNNQPNCPLCLLRSEFLVSEIIQSYTSLRSSLLDALRIPKPTPVPENEEVPGPENSSWIELISESESDSVNAADDDLQIVATSERKLAKRSMTDILPLSSKPSKRNFAMFRSERIKKKSKPNEQMAQCPICQQFYPLKALEKTHLDECLTLQSLGKKPKISTTFPTESNPHNKSSSRFKVRTPEVDKSSCGETSHVDKYLNSMMSAEHQRLPKITSMTQSQIKQKLS---------GLSTNGTRQNMIKRYNHYEML----------------------WNSNFCDSLEPVDEAELKRQLLSWDVSHNKTPQNSSNKGGISKLMIMKSNGKSSSYRKLLENFKNDKFNR-KGWMVMF----RKDFARL---IREAKM................................. 404
35 -11.900[O] COG3058 Uncharacterized protein involved in formate dehydrogenase formation  ali follow..  25  190.......................................CPVCGSMPQGLRY--LHCNLCET-VVRV-------KCSN---CEQSGKLHESCDDCGYLKILYQELVLDARMEQE............................................................................................................................................................................................................................................................................................................................................................................................. 292
36 -11.800[O] COG5243 HRD ubiquitin ligase complex, ER membrane component  ali follow..  7  310LYQSGTSLWKIWRNNKQLDDTLVTVTVEQLQNSANDDNICIICMDEIHSPNQQTWKNKNCGHILHLS--------CLKN-------ERSQTCPICRLPVFDEKGNVVQTTFTSNSDITTQTTVTDSTGIATDQQGFANEVDLLPTRTTSPDIRIVPTQNIDTLAMRTRSTSTPSPTWYTFPLHKTGDNSVGSSRSAYEFLITNSDEKENGIPVKLTIENHEVNSLHGDGGEQIAKKIVIPDKFIQH......................................................................................................................................................................................................................................................... 550
37 -11.700[R] KOG4377 Zn-finger protein  ali follow..  14  269.TASAVAATTINSGQRTAAKRNRDHDIPSGYLKFRFNEDC--CGYRNHQSHF----CRDCDDFFRANMRKTSHFHC---RKCKVVAHRREQCPGCSYAQCVTCDGRAQLAAHKHRTGFPKQEA.................................................................................................................................................................................................................................................................................................................................................................................... 489
38 -11.600[B] KOG1973 Chromatin remodeling protein, contains PHD Zn-finger  ali follow..  15  240.AQKKTVEVDDSEKESCHTAATHPSDVMDMPVDPNEPTYC-LCHQVS----YGMIGCDNCP-WFH--------FACVG-----LTTKPKGKCPKCTQDR............................................................................................................................................................................................................................................................................................................................................................................................................ 325
39 -11.600[S] KOG2660 Locus-specific chromosome binding proteins  ali follow..  8  14......................................................LSCSICDNILRDATT------S---EKCIITEDEIETCPVCNIDEKLRPDHNLQDLRAKIFALKRRKVKAPGIVSLPGKRKERSISSLVVSTPMVSAQAGTTRRRTKAPTRKELRNGSLAERTVKKEESSGDELLESTSSPDTLNKFTQNKRQSKKSCKESISNKENKDGDEPWDSKMDWKPLNFLVEVANGTKPLKSSASQGSGSKSEHANVSRNQFQGSKTKTKNKKRKCKREDDKSNNGDPTTSETVTPKRMRTTQRKRSATTLGDSRNLPQPDESSAWFSLVASNDQGTSLPQIPANFLRIRDGNT-----------------VSFIQKYL--MRKLDLESENEIEIKC--------EAVIPTLTLYNLVDLWLQK-HQRFAALVGSSAKDF---TMVLVYARKLPECNM........................... 414
40 -11.500[T] KOG1701 Focal adhesion adaptor protein Paxillin and related LIM proteins  ali follow..  27  416.......................................CARCGENVVGFHVDCFTCIICQPFYA---VEKKAY-CEP-NVC-LRATGKATCVMCH-PRCSVCK....................................................................................................................................................................................................................................................................................................................................................................................................... 540
41 -11.400[O] KOG1813 Predicted E3 ubiquitin ligase  ali follow..  13  241...EEAEKVRKRNKAMGVEDEDDEADKDSDEDENALPFACFICREPFV-----VVT---CKHYF-----------C---EHCALKHHTKNKCFVCNFNAAHEIKKRMAEERSKAEQGLRRLWPVGEVVPKSK........................................................................................................................................................................................................................................................................................................................................................................... 357
42 -11.300[O] COG5540 RING-finger-containing ubiquitin ligase  ali follow..  20  284..SREGFYSEEEEIENSTQNGELVPLMDESTRRATFGVECVICLESTKGDKVVALPC---KHEF--------------HRPC-IAKDYRHACPTCNTE............................................................................................................................................................................................................................................................................................................................................................................................................. 365
43 -11.300[B] COG5034 Chromatin remodeling protein, contains PhD zinc finger  ali follow..  15  213.RRPVRRSESRLKQTNGEPLVKHDTLDSSDISREGEQLYC-YCQQVS----YGMIGCDNCK-WFH--------LPCVG-----LVEPPKGICKECEELA............................................................................................................................................................................................................................................................................................................................................................................................................ 298
44 -11.200[O] KOG0978 E3 ubiquitin ligase involved in syntaxin degradation  ali follow..  19  818..........ELEELGSESVEAAIVRLQEEVKNCKNILKCGVCFDRPKE----VIV---CYHLF-----------C---QQC-IQEIRHRKCPGCG------TAFGQNDVR................................................................................................................................................................................................................................................................................................................................................................................................ 895
45 -11.200[R] COG5222 Uncharacterized conserved protein, contains RING Zn-finger  ali follow..  10  251VEDKQSWEDYQRKRENRQIDGDETIWRKGHFKDLPDDLKCPLTGGLLRQ----TSKC--CNIDF-----------S---KEALENAESDFVCPNCETRDILLDSLVPDQDKEKEVETFLKKQEELHGSSKDGNQPETKKMKLMDPTGTAGLNNNTSLPTSVNNGGTPVPPVPLPFGIPPFPMFPMPFMPPTATITNPHQADASPKK................................................................................................................................................................................................................................................................................................. 441
46 -11.100[O] KOG0824 Predicted E3 ubiquitin ligase  ali follow..  22  2.................NASTSSPSQQLQQAINSTIDKECAVCYSEMI------TTIPSCGHKF-----------CF---ICLKGVSNNGDCPICR............................................................................................................................................................................................................................................................................................................................................................................................................... 64
47 -11.000[R] COG5152 Uncharacterized conserved protein, contains RING and CCCH-type Zn-fingers  ali follow..  15  225..........DSVQEKYKKGAKLEEGMVKNEKKEDIPFVCLICKKDYR-----IAT---CGHHF-----------C---EQCAITRYRKTTCIQCGFDRLLKNRKSKNDEAVKQKVGGFESNNSATTEVSERKDREAS..................................................................................................................................................................................................................................................................................................................................................................... 346
48 -11.000[R] COG5084 Cleavage and polyadenylation specificity factor (CPSF) Clipper subunit and related makorin family Zn-finger proteins  ali follow..  15  229................................EPTRKTICPRCAEDCNLSHFGKCNCR-CFEFAKYGF-------CELGTSC--KNQHILQCTDCNNPQCSLYHGAVSADVPEQTEAPISKTAGSINPEDSGSEIGSNSLESN................................................................................................................................................................................................................................................................................................................................................................ 371
49 -10.800[O] KOG1039 Predicted E3 ubiquitin ligase  ali follow..  17  205......DPEQRKAHEKICMLTFEHEMEKAFAFQASQDKVCSICMEVISERRFGILSCLSCIRQWRCAFENPIIKSCPE---CRVQGMGKKACKYCPFSKCLYRHAYPDGRLAEPEKPRKQLSSQGTVRFFNS........................................................................................................................................................................................................................................................................................................................................................................... 375
50 -10.700[R] KOG1819 FYVE finger-containing proteins  ali follow..  13  534.QVANSQTEGEETGVEAQETLPLPAFMGVRWVPDEDCEQCTACSMPFN-RHH----CRNCGRIF-----------C---HKCSYDRKPV--SSPQ................................................................................................................................................................................................................................................................................................................................................................................................................ 621
51 -10.700[TZ] KOG1044 Actin-binding LIM Zn-finger protein Limatin involved in axon guidance  ali follow..  10  74.......................................CAGCGRLALDWHLGCFKCKSCGEYISK---DGAPY-CEKDEACAGDKHYHPSCARC--SRCQSLGESPRTLSPTPSAEGYQDVRDRMIHRSTSQGSINSPVYSRHSYTPTTSRSPQHFHRPGNEPSSGRNSPLPYRPDSLPLTPTYAQAPKHFHVPDQGINIYRKPPIYKQHRALAAQSKSSEDIIKFSKFPAAQAPDPSETPKIETDHWPGPPSFAVVGPDMKRRSSGREEDDEELLRRRQLQEEQLMKLNSGLGQLILKEEMEKESRERSS-LLASRYDSPINSASHIPSSKTASLP----GYGRNGLHRPVSTDFAQYNSYGDVSGGVRDYQTLPDGHMPAMRMDRGVSMPNML--EPKIFPYEMLMVTNRGRNKI--LREVDRTR------LERHL------APEVFREIF-RLPLWRRNDMKKKAKLF....................... 626
52 -10.700[K] KOG2461 Transcription factor BLIMP-1/PRDI-BF1, contains C2H2-type Zn-finger and SET domains  ali follow..  10  622.......................................CGTCGKKYI-THWKTTTCKEEMKDSMRDDLMDIKGEI---DEGNLGIFEN-PLMPISGMQEQQAPPQHMMYGNTMGHMGQGSH..................................................................................................................................................................................................................................................................................................................................................................................... 747
53 -10.600[O] KOG4628 Predicted E3 ubiquitin ligase  ali follow..  9  224............................TKNNANNKYDTCVICEDFIEDDKLRVLPCS-----YHTH--------C-------IDTENRRVCPICKRKVFTKGEARASRSRQPSLDNVTDTDDDTTPLLQQQQSNGRQVGQVSSASSAGGAAGSSSSVAAAAVAGTTRHGTFRRGHAGRNPFEESQSSDDENALLASTVRPATSSGAHERINPFDRAPNLPAHLAEQLTESRRS..................................................................................................................................................................................................................................................................... 415
54 -10.600[R] KOG1844 PHD Zn-finger proteins  ali follow..  10  85...SKNEVGIFTTPNFDETSSATTISTSEDGSYGTDVTRC-ICGTHDDGY---MICCDKCSVWQH---------DCMG-----IDRQHIPDTYLC--ERCQPRNLDKERAVLLQRRKRENMSDGDTSATESGDEVPVELYTAFQHTPTSITLTASRVSKVNDKRRKKSGEKEQHISKCKKAFREGSRKSSRVKGSAPEIDPSSDGSN................................................................................................................................................................................................................................................................................................ 270
55 -10.600[R] KOG0153 Predicted RNA-binding protein (RRM superfamily)  ali follow..  20  2...................SKTTNTYNRQNWEDAEFPILCQTCGDRMIKERFG--ECKICRPFFRWCPGARMRFK--KTEICQTCARLKNVCQTCLLD--LEYGLPIQV.................................................................................................................................................................................................................................................................................................................................................................................................. 94
56 -10.600[O] KOG0802 E3 ubiquitin ligase  ali follow..  9  339.................LGALHAALPDATSEELRAYDDECAICREPMAK----------CNHLFHLG--------CLRS--LDQGLNEVYSCPTCR--KPLFVGRTENEVNPRTVEVSSDEQLARQLERQNNPVHALATGLFPAEVPDSVENDTSRNLGLDPSWLQTWSSQGSDVAGPSTTSRTVGLGRVQMMMRHLASVGESYAQTALDDAAWSLWPMNPSQASTSSTTVPPGNGGRTGGLHLRTVSNTTNESLTNILAMAET....................................................................................................................................................................................................................................... 569
57 -10.600[S] KOG4791 Uncharacterized conserved protein  ali follow..  20  8..........................................C------YFFFYSTCKGCP--FRHCAALGNETVCTQEGRC------RRVCRFCQKLNC........................................................................................................................................................................................................................................................................................................................................................................................................... 80
58 -10.400[R] COG5063 CCCH-type Zn-finger protein  ali follow..  10  138..QKPKNDASFSSEKESSAQPKVKSQVQETPKQLYKTELCESC-------PYG--KCQFAHGLGEKVKKSCKNFRCVKLGYCP----YGRRCCFKHGDDNDIAVYVKAGTYCNVSSTSKQSDEKRSNGRGSAKKKNLNVKVKALQRMT........................................................................................................................................................................................................................................................................................................................................................... 284
59 -10.300[O] KOG2231 Predicted E3 ubiquitin ligase  ali follow..  15  10.ARPSFHRRPKDGVANTTTDNAAVKPEALESYTGNDDNACVVCFKNVE--IFSIGDCD-C-------------YECSQQNECPICRHVDHPCPKCDLRNCVE--YTQAELQLHNTKGDPDN...................................................................................................................................................................................................................................................................................................................................................................................... 200
60 -10.200[R] KOG4582 Uncharacterized conserved protein, contains ZZ-type Zn-finger  ali follow..  25  116............................................PSNFTIHDAV-ECDGCGGF--R-------YKCV---QCS----NYDLCQKCELAH............................................................................................................................................................................................................................................................................................................................................................................................................ 158
61 -10.200[D] KOG3056 Protein required for S-phase initiation or completion  ali follow..  20  456..................RKEAMEEKMLTTYKMPCKAVICQVCKDRCKEQKHPLKVVDAEKRFFQ----------C---KDCTVFKLPKQSCKNCKGSRWQRTAMIRESVRGDEET........................................................................................................................................................................................................................................................................................................................................................................................... 562
62 -10.200[U] KOG4173 Alpha-SNAP protein  ali follow..  11  62...................QDVIMQVADVPEKPRVPAFACQVCCQVFDALHYHTLHCSFCRAFFQILSERQDMYQCLVEG-CHMVRMHLYPADF----RFDKPKKSRSPASAEAPGDSGERSEGEAMEICSEPVAASPAPAGERRIYRHRSVSELFLKPVLNMCSVLRILGCTWAAALLILNSE....................................................................................................................................................................................................................................................................................................................... 261
63 -10.200[O] KOG4400 E3 ubiquitin ligase interacting with arginine methyltransferase  ali follow..  14  41.DNMKASFGSSKRYDERQKKKRSEYRRLRRINQRNRDKFCFACRQ--QG-HINVSICFRCKEHSLNACSKKGPFICHENGQCEQNPKKGGCCKFCS-KDCDQVNKDDVSF................................................................................................................................................................................................................................................................................................................................................................................................. 176
64 -10.100[R] KOG3183 Predicted Zn-finger protein  ali follow..  10  13.......................................CSVCKD------FLPFTCDRCLQVYCLDHRSYMKHDCPKKKKCPVPRCRELKCRDCSIDHCLK--------RFGPDHSCSGPKKPESSFSFMGFLSTNTKEAPASSSSSSRWSSLFASAEASISRLGNDISQKLQFASGNDGNSEKTQERNGK............................................................................................................................................................................................................................................................................................................... 211
65 -10.100[C] COG0348 Polyferredoxin  ali follow..  16  197.......................................CGLC-----GAAYGVIGCDNCM-------------DC--YNVCPEPLVLSKDCISC---RCIDV-CPEKVFIFTTRFNHSVNHSGE.................................................................................................................................................................................................................................................................................................................................................................................. 291
66 -10.000[S] KOG4149 Uncharacterized conserved protein  ali follow..  13  161.QIATGKDDDEYARKFEEVEEESSEESAFNPDTGEINWDCPCLGGMAHG---------PCGEEFKAA------FSCFVYSK---SEPKGMECKFQAMQACFQKHPEQDMVGESEEEDAETNEKPSTTSDENNQPQSPPSDNASNPEEDVMNMEKEIVNLTPMSVIK......................................................................................................................................................................................................................................................................................................................................... 311
67 -10.000[R] KOG3608 Zn finger proteins  ali follow..  20  263.......................................CTMCDMTCS-RHLK-LKCSECDTRCVQIVHSKTVHQC-EHPDCQMRRHFLEACHCCFFKSGKSLSAHLMKKHGFRLPSGHKRFTYRVDENGFYRLETTRLES.................................................................................................................................................................................................................................................................................................................................................................. 403
68 -10.000[DR] KOG1101 Apoptosis inhibitor IAP1 and related BIR domain proteins  ali follow..  22  533.STLYKNLFVDKNMKYIPTEDVSGLSLEEQLRRLQEERTCKVCMDKEVSVVFGLVVCQECAPSLRK-------------------------CPICRIKGTVRTFLS..................................................................................................................................................................................................................................................................................................................................................................................................... 618
69 -9.990[P] KOG1603 Copper chaperone  ali follow..  13  1MATDKSETKKTEHKQKQSTQIKQDLPPPTIPPLPLPYKSCTL---KVS-IH-----CEGCKRKVKKILTS----------KVDIDVKQHK------LKKLNKAGKNAEQLPEIPDPVDNKPKPVDPKEKNKKKKKEEKVQITNEATSSGIDNPEKPGSGECDKPESEKPVDEKCLSGDGGETSGPVKEEKKD............................................................................................................................................................................................................................................................................................................... 186
70 -9.940[R] KOG4684 Uncharacterized conserved protein, contains C4-type Zn-finger  ali follow..  15  20.NVTPTAPPYLQESSPRAELPPPYTAIASPDASGIPVINCRVCQNLDGKLHQHVVKCTVCN---KKYVRTSRRIGCPRP-NCR-PEGTRVVCGHCGLAKCPHCKKICSSSVGSALPRRR........................................................................................................................................................................................................................................................................................................................................................................................ 193
71 -9.900[L] COG0551 Zn-finger domain associated with topoisomerase type I  ali follow..  12  100.....................LIEEGSFKIKGYDGPVVECDKCGADMFGKYMGCLKCEKSDAFVLRDGASGVFMSAHNFPKSRETRADAPQKDPEENEAIVRFSRKEKKQYVTSEKEGKATKWIVDFTNGKWVERKK...................................................................................................................................................................................................................................................................................................................................................................... 270
72 -9.760[S] KOG4623 Uncharacterized conserved protein  ali follow..  19  43.......................................CWFCNGNVDRNSW---TCPSCEGDYNRDIPAPKNGLC---DQCELKVYRER-CSSCEVNKVLH--EKKKMVLSSKFLNYIIKGASLLKQPHFNRLAAAQKQ................................................................................................................................................................................................................................................................................................................................................................... 215
73 -9.680[R] COG5236 Uncharacterized conserved protein, contains RING Zn-finger  ali follow..  17  26.KPHNDRKNFRRKQKKNNLSAEPNLTTSSADDTDEENELCVICARKLT--H----TCHICCDFYNEHLKSEICLICATHKHAQLRNHQTKMCAFCSGKRFYSDDELYIHMRNQH............................................................................................................................................................................................................................................................................................................................................................................................. 246
74 -9.630[R] KOG1314 DHHC-type Zn-finger protein  ali follow..  21  78................VGPGFVPLGWKPEISQDTMYLQYCKVC--KAPRSHH----CRKCN----RCVMK-MDHHCPWINNCC----YQNHASFTLFLLLAPLGC...................................................................................................................................................................................................................................................................................................................................................................................................... 155
75 -9.620[C] COG1150 Heterodisulfide reductase, subunit C  ali follow..  12  2VEPRDTVIREEDLNPDFLEELSELVEPVFEEEEVLSVQACYQCG-----------TCTGCPGLVDEVIKSDELWMCTT-------------CYTCY-ERCAVKAARNLAAKKGYMAKAHRM...................................................................................................................................................................................................................................................................................................................................................................................... 124
FFAS is supported by the NIH grant R01-GM087218-01
1 4 6 8 3 9   jobs submitted since Jan 1, 2011
Comments and questions to: webmaster
Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Bourne PE, Allerston CK, Krebs W, Li W, Shindyalov IN, Godzik A.,Friedberg I, Liu T, Wild D, Hwang S, Ghahramani Z, Chen L, Westbrook J. The status of structural genomics defined through the analysis of current targets and structures. Pac Symp Biocomput. 2004;:375-86.