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Query: [T] KOG4220 Muscarinic acetylcholine receptor, from COG1018

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MEGDSYHNATTVNGTPVNHQPLERHRLWEVITIAAVTAVVSLITIVGNVLVMISFKVNSQLKTVNNYYLLSLACADLIIGIFSMNLYTTYILMGRWALGSLACDLWLALDYVASNASVMNLLVISFDRYFSITRPLTYRAKRTPKRAGIMIGLAWLISFILWAPAILCWQYLVGKRTVPLDECQIQFLSEPTITFGTAIAAFYIPVSVMTILYCRIYRETEKRTKDLADLQGSDSVTKAEKRKPAHRALFRSCLRCPRPTLAQRERNQASWSSSRRSTSTTGKPSQATGPSANWAKAEQLTTCSSYPSSEDEDKPATDPVLQVVYKSQGKESPGEEFSAEETEETFVKAETEKSDYDTPNYLLSPAAAHRPKSQKCVAYKFRLVVKADGNQETNNGCHKVKIMPCPFPVAKEPSTKGLNPNPSHQMTKRKRVVLVKERKAAQTLSAILLAFIITWTPYNIMVLVSTFCDKCVPVTLWHLGYWLCYVNSTVNPICYALCNRTFRKTFKMLLLCRWKKKKVEEKLYWQGNSKLPLast
1 -112.000[T] KOG4220 Muscarinic acetylcholine receptor  ali  100  1MEGDSYHNATTVNGTPVNHQPLERHRLWEVITIAAVTAVVSLITIVGNVLVMISFKVNSQLKTVNNYYLLSLACADLIIGIFSMNLYTTYILMGRWALGSLACDLWLALDYVASNASVMNLLVISFDRYFSITRPLTYRAKRTPKRAGIMIGLAWLISFILWAPAILCWQYLVGKRTVPLDECQIQFLSEPTITFGTAIAAFYIPVSVMTILYCRIYRETEKRTKDLADLQGSDSVTKAEKRKPAHRALFRSCLRCPRPTLAQRERNQASWSSSRRSTSTTGKPSQATGPSANWAKAEQLTTCSSYPSSEDEDKPATDPVLQVVYKSQGKESPGEEFSAEETEETFVKAETEKSDYDTPNYLLSPAAAHRPKSQKCVAYKFRLVVKADGNQETNNGCHKVKIMPCPFPVAKEPSTKGLNPNPSHQMTKRKRVVLVKERKAAQTLSAILLAFIITWTPYNIMVLVSTFCDKCVPVTLWHLGYWLCYVNSTVNPICYALCNRTFRKTFKMLLLCRWKKKKVEEKLYWQGNSKLP 532
2 -76.900[R] KOG3656 FOG: 7 transmembrane receptor  ali follow..  26  52VTASPAPTWDAPPDNASGCGEQINYGRVEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAVMPFVSVTDLIGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAKMILSVWLLSASITLPPLFGWAQNVNDDKV------CLISQDFGYTIYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFPGFPRVEPDSVIALNGIVK-----------------------------------------------------------------------------------------------------------------------------------------------------------------LQKEVEECANLSRLLKHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICSCIPLWVERTFLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYRNINRKLSAAGMHEALK. 420
3 -58.800[T] KOG4219 G protein-coupled receptor  ali follow..  19  1MDNVLPVDSDLSPNISTNTSNQFVQPAWQIVLWAAAYTVIVVTSVVGNVVVMWIILAHKRMRTVTNYFLVNLAFAEASMAAFNTVVNFTYAVHNEWYYGLFYCKFHNFFPIAAVFASIYSMTAVAFDRYMAIIHPLQ--PRLSATATKVVICVIWVLALLLAFPQGYYSTTETMPSRVVCMIEWPEHPNKKVYHICVTVLIYFLPLLVIGYAYTVVGITLWASEI-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PGDSSDRYHEQVSAKRKVVKMMIVVVCTFAICWLPFHIFFLLPYINPDLFIQQVYLAIMWLAMSSTMYNPIIYCCLNDRFRLGFKHAFRCCPFISAGDYEGLEMKSTRY. 341
4 -34.600[T] KOG2087 Glycoprotein hormone receptor  ali follow..  18  364...............................ILRVLIWFISILAITGNIIVLVILTTSQYKLTVPRFLMCNLAFADLCIGIYLLLIASVDIHTKDWQTG-AGCDAAGFFTVFASELSVYTLTAITLERWHTITHAMQLDCKVQLRHAASVMVMGWIFAFAAALFPIFGISSYMKVSI----PMDIDSPLSQLY-VMSLLVLNVLAFVVICGCYIHIYLTVRN--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PNIVSSSSDTRIAKRMAMLIFTDFLCMAPISFFAISASLKVPLITVSKAKILLVLFHINSCANPFLYAIFTKNFRRDFFILLSKCGCYEMQAQIYRTETSST.. 661
5 -11.600[S] KOG4610 Uncharacterized conserved protein  ali follow..  11  1..................................MAKIISTIKAILTRIIFLLAIWQVVALKSDIIYWALCGPLLLLLLGIFTI-LYLSSIVPAIWLLELDKVALSVTPDTWTTLIEQFLMLILIVGRWLDLTRDYKDDSIAKIGFLVFLTLGIWSWSLMQFTIVLSATRGGSHHKEEHTDCCQNCCCGIDVWGIVLNVILQDAPFLTFRLLYMNVFFTCKNSLVIILQLYRLYVVNAEFWKNRRESRMAKSRQFQSRRKVQDADQNSIYMISNERGGDVKKKIKRAKDKDYAEQEAVYSKKKKDKKDKKKRKRKDTGYSTASSQNLYSTKASGTDKDTRRKDKKGKKSKRTCSSSPSDCDLAKKQKRKNADKNDKKKSRKIEAVVEESSSSSSSSSDSSNSTLPSYEVIDEKKARRRKHRGSSSDTSSGDSSSSSSSSSSS.......................................................................................... 520
6 -9.580[I] KOG3845 MLN, STAR and related lipid-binding proteins  ali follow..  10  1............................................MSGRQPLISPGSQRIGVSKDRKRFIV-ITFFDTSITILL------------WLL-KVFFNEINIFNPKFIRISLFDIVLLAVLRMLILG--VVYGICLVKQWYTVAFTTLASSAYILMKVLFYFNHS-----------------SSAVPPLLLIITSFTLCWSEFYLMPFQILPRERRYARRELDGIENPEFSTDDEARSNNRHRRGRRQQNSGNQSEAPTAVPSRVSSGVFIASDYDEFRSAAEFSSDEEA............................................................................................................................................................................................................................................ 229
7 -8.930[T] KOG4193 G protein-coupled receptors  ali follow..  13  396......................................LLDVITWVG-LICIFTFCFFRGLQSDRNTIHKNLCIS-FLIGIFAALLHFFFLAAFTWMVGDKVC--WLRLDIIMLNVIFLGIALYKMFHHTAILKPESGCLDNINYELLCLLGLTWAFGLMYINESTVIMAYL--------------------FTIFNSLQGMFI-----FIFHCVLQKKVRKEYGKCLRTHCCSGKSTESSIGSGKTSGSRTPGRYSTGSQSRIRRMWNDTVRKQSESSFITGDINSSASLNREPYRETSMGVKLNIAYQIGASEQCQGYKCHGYSTTE........................................................................................................................................................................................................... 759
8 -8.740[R] KOG0835 Cyclin L  ali follow..  8  74....................................................LDLPSETDLRILGCELIQALRLPQVAMATGQVLFHRFFYSKSFVKHSAMAC-INLA-DVINVFHHLRQLKELGFC--VHVKHPVMYLQVLECERNQTLVQTAW-TNVFVRFQP--------------------ETIACACIYLAARALQIPLPCIETLRLYTRKKPNYELLEKEVEKRKVALQEAKLKAKGLNPDGTPALSTLGGFSPASKPSSPREVKAEEKSPISINVKTVKKEPEDRQQASKSPYNGVRKDSKRSRNSRSASRSRSRTRSRSRSHTPRRHYNNRRSRSGTYSSRSRSRSRSHSESPRRHHNHGSPHLKAKHTRDDLKSSNRHGHKRKKSRSRSQSKSRDHSDAAKKHRHERGHHRDRRERSRSFERSHKSKHHGGSRS......................................................................................... 519
9 -8.730[S] COG3859 Predicted membrane protein  ali follow..  9  16...............................................NVRLLTEIAFMAALAFIIS-LIPNTVYGWIIVEIACIPILILSFRRG-LTAGLVGGLIWGILSMITGHAYILTLSQAFLEYLIAPV----FRQKTASLKLVPVLLGTFVAVLLKYFFHFIAGIIFWSQYAWKGWG---AVAYSLAVNGISAILTAIAAFVILIIFVKKFPKLFIYSN.................................................................................................................................................................................................................................................................................................................... 190
10 -8.660[I] COG0671 Membrane-associated phospholipid phosphatase  ali follow..  11  79...................................MAPFWIKVYKGTGAITLGFLAWKRYWSEIKYLVFATLGILLVIDQVLKPPLPRLVDVDGSFPSGHAAGGFYFYLAFLLALGATLWVGFIGIASYCRVHWA-------TDILAGYGVGFIWLTLSLF................................................................................................................................................................................................................................................................................................................................................................................... 226
FFAS is supported by the NIH grant R01-GM087218-01
1 4 8 3 4 1   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Jaroszewski L, Slabinski L, Wooley J, Deacon AM, Lesley SA, Wilson IA, Godzik A. Genome pool strategy for structural coverage of protein families. Structure. 2008 Nov 12;16(11):1659-67.