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Query: [D] KOG4259 Putative nucleic acid-binding protein Hcc-1/proliferation associated cytokine-inducible protein, contains SAP domain, from COG1018

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MPESDVTKMKVADLKRELKLRGLAVNGNKTELQDRLQTALLEGDLSLEDSAIADAIDDDDVSFTDEDEHKLLGDENDDELLKSPVSTPTTVAIPDLLAEEKTSSAPDAAAPTKKIVLKRNNSQQSTGTVASTGTTPSKENEAPAAAASDSTGETPTKKHKPIVVGPKTEGEKPSGDKKLNQLTAQERLELRAKKFGITPPAVANTATAVAVAINKSSSASITANKGNKETEEQQKEALKKRAERFGFVVPDKAPTSKADDRLQKRKERFGAGAVSAATTTPTTTESKDAWSEKARARLERFKTAPSTNLast
1 -74.900[D] KOG4259 Putative nucleic acid-binding protein Hcc-1/proliferation associated cytokine-inducible protein, contains SAP domain  ali  100  1MPESDVTKMKVADLKRELKLRGLAVNGNKTELQDRLQTALLEGDLSLEDSAIADAIDDDDVSFTDEDEHKLLGDENDDELLKSPVSTPTTVAIPDLLAEEKTSSAPDAAAPTKKIVLKRNNSQQSTGTVASTGTTPSKENEAPAAAASDSTGETPTKKHKPIVVGPKTEGEKPSGDKKLNQLTAQERLELRAKKFGITPPAVANTATAVAVAINKSSSASITANKGNKETEEQQKEALKKRAERFGFVVPDKAPTSKADDRLQKRKERFGAGAVSAATTTPTTTESKDAWSEKARARLERFKTAPSTN 308
2 -37.000[A] KOG2242 Scaffold/matrix specific factor hnRNP-U/SAF-A, contains SPRY domain  ali follow..  15  1...MDVRRLKVNELREELQRRGLDTRGLKTELAERLQAALEAEEPDDERELDADDEPGRPGHINEEVETEGGSELEGTAQPPPPGLQPHAEPGGYSGPDGHYAMDNITRQNQFYDTQVIKQENESGYERRPLEMEQQQAYRPEMKTEMKQGAPTSFLPPEASQLKPDRQQFQSRKRPYEENRGRGYFEHREDRRGRSPQPPAEEDED..................................................................................................... 204
3 -23.200[K] KOG4661 Hsp27-ERE-TATA-binding protein/Scaffold attachment factor (SAF-B)  ali follow..  11  27.GTRRLSDLRVIDLRADVRKRNVDSSGNKSVLMERLKKAIEDEGGNPDE-TSEGNKKTSKRSSKGRKPEEEGVEDNGLEENSGDGQEDVETSLENLQDIDIMDISVLDEAEIDNGSVADCVEDDDADNLQESLSDSRELVEGEMKELPEQLQEHAIEDKETINNLDTSSSDFTILQEIEEPSLEPENEKILDILGETCKSEPVKEESSELEQPFAQDTSSVGPDRKLAEEEDLFDSAHPEEGDLDLASESTAHAQSSKADSLLAVVKREPAEQPGDGERTDCEPVGLEPAVEQSSAASE......... 326
4 -15.300[O] KOG4275 Predicted E3 ubiquitin ligase  ali follow..  11  47LSRTDLLKLKPKDLIFYLQSKHISTEG-KEELVGLVLTHVAQVDRSRGSNASSNSPGRGQANPIDSLKQSCQNFFSNLSDNISDSLASFDSKVTTKPPESRQPEVPTHIFEQPRVSTREIPTYASAVNGGPQHVHVQQQATTTNGGSQSSSSPSTSTQSSNNRDASSSSQAHVAHQEARNEEQEDAQSKSDCECSDEEIMATFSERVSISLKTDTSGRRVNAAAEPSPVDLANVDNGPAGNTAPSPGCSKPGSSSSKADASSQSSFEELGAIGGISDESKANTDTNSSHLDQWQ.............. 342
5 -12.100[L] KOG2327 DNA-binding subunit of a DNA-dependent protein kinase (Ku70 autoantigen)  ali follow..  23  568ISKGTLGKFTVPMLKEACRAYGLKSGLKKQELLEALTKHFQD.......................................................................................................................................................................................................................................................................... 609
6 -10.800[T] KOG4590 Signal transduction protein Enabled, contains WH1 domain  ali follow..  23  377LDAFDLDRMKLEEVVRELHK-------VKEEIIDAIRQELSGISTT...................................................................................................................................................................................................................................................................... 418
7 -10.600[R] KOG2295 C2H2 Zn-finger protein  ali follow..  10  169ISDSEVMR-KYTEYKTDFKRQQLNEVAHKDEFMELLENKVDSSQADALIRVLDTCVIKLEGGTDEDLKVLDEKPKDPVVYERKAEQMQSVKEVEKTINSPKEEMSEADPVSTQRKPVRPVNSDGENWDDDDAENSAPKKELAEDSKDSDSKPEDKQLNKKKTKKRKRNSSDDDSSSSESSSSSDEEKLKEKYDVEDGLRAEQKTEAEKDRQEATKAKQGPQSPKLDEDEGNENTEPKGLDSKINTYEEIDNTLKSPEISSNPIKNTDNGDGSKVEEDGEKPSVGKDKVVETETIDLDKVK........ 504
8 -10.300[R] KOG2350 Zn-finger protein joined to JAZF1 (predicted suppressor)  ali follow..  8  609......TEIVRKNLYRNLFDYGLIAAETVYKTVQKLQGLLSKYAAGQELMQRQREEQLKYWLDVGMHKKQEDPKTLKSPQKPAPPADQASTSSASTSGSGSGSSSMQPPKRMPAHLKRGSAASSPGVQSKGTENGTNGSNSSSSNSKNVAKKSADQPLSTLANTRERRSEYGQKRNVSGSRLAATPASKRKLSSKDVEQAADAPEVLTHSDNAVDVGIIDDECGGFGAVGVMNGVASPVANNSEMDTEAEVEAEPTATKAITIHCQQPVTTPVAAAATANERLPGVAPHRRGPRRADRREEELVASA. 916
9 -10.200[S] KOG2827 Uncharacterized conserved protein  ali follow..  31  421.SAEDLELLGLEHLKSALNDRGLKCGGSLVERAARL................................................................................................................................................................................................................................................................................ 455
10 -9.560[T] COG5432 RING-finger-containing E3 ubiquitin ligase  ali follow..  26  273LPKINFTSMTQSQIKQKLSSLGLSTNGTRQNMIKRYNH.............................................................................................................................................................................................................................................................................. 310
11 -9.560[L] KOG0287 Postreplication repair protein RAD18  ali follow..  26  273LPKINFTSMTQSQIKQKLSSLGLSTNGTRQNMIKRYNH.............................................................................................................................................................................................................................................................................. 310
12 -9.330[U] KOG0946 ER-Golgi vesicle-tethering protein p115  ali follow..  8  657.NMIREQDLQLEELRQQVSTLKCQNEQLQTAVIQQHKDQYNLLKIQLGKDNQHQGSYSEGAQMNGIQPEEIGRLREEIEELKRNQELLQSQLTEKDSMIENMKSSQTSGTNEQSSAIVSARDSEQVAELKQELATLKSQLNSQSVEITKLQTEKQELLQKTEAFAKSVEVQGETETIIATKTTDVEGRLSALLQETKELKNEIKALSEERTAIKEQLDSSNSTIAILQTEKDKLELEITDSKKEQDDLLVLLADQDQKILSLKNKLKDLGHPVEEEDELESGDQEDEDDESEDPGKDLDHI....... 962
13 -9.320[S] KOG1043 Ca2+-binding transmembrane protein LETM1/MRS7  ali follow..  10  295LKADDVDALSSIDLQSACRARGMRAIGSEERLKEQLVQWLELSLNDKVPPPDRLKAIVQNLPDGLAETTKQKLTEMEGGQIDHKARIELIRSIESAIANEKKDEEKKKKAAEEALKSKEEAEKAKVQEKEKLVDVAAQAIVHELKKDIYDAVASTSSTTEAKEPAAKPSEAKEEKKEDITVDKKDLSHIEEIIVGGPIKEAKHDILGLREKVLEHKEDLMEINSLDGAFAETKIAKRLRHKLNSMIEDVDSMVDKLEDEKRDLKKEREVRIQDVIDSLAKLKESKGEQADDGEQRERIEALTIDEDSD 645
FFAS is supported by the NIH grant R01-GM087218-01
1 4 8 3 1 9   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Ye Y, Godzik A. Multiple flexible structure alignment using partial order graphs. Bioinformatics. 2005 Mar 3;