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Query: [R] KOG4368 Predicted RNA binding protein, contains SWAP, RPR and G-patch domains, from COG1018

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MTMEKQKDNPKFSFLFGGEFYSYYKCKLALEQQQLICKQQTPELEPAATMPPLPQPPLAPAAPIPPAQGAPSMDELIQQSQWNLQQQEQHLLALRQEQVTAAVAHAVEQQMQKLLEETQLDMNEFDNLLQPIIDTCTKDAISAGKNWMFSNAKSPPHCELMAGHLRNRITADGAHFELRLHLIYLINDVLHHCQRKQARELLAALQKVVVPIYCTSFLAVEEDKQQKIARLLQLWEKNGYFDDSIIQQLQSPALGLGQYQATLINEYSSVVQPVQLAFQQQIQTLKTQHEEFVTSLAQQQQQQQQQQQQLQMPQMEAEVKATPPPPAPPPAPAPAPAIPPTTQPDDSKPPIQMPGSSEYEAPGGVQDPAAAGPRGPGPHDQIPPNKPPWFDQPHPVAPWGQQQPPEQPPYPHHQGGPPHCPPWNNSHEGMWGEQRGDPGWNGQRDAPWNNQPDAAWNSQFEGPWNSQHEQPPWGGGQREPPFRMQRPPHFRGPFPPHQQHPQFNQPPHPHNFNRFPPRFMQDDFPPRHPFERPPYPHRFDYPQGDFPAEMGPPHHHPGHRMPHPGINEHPPWAGPQHPDFGPPPHGFNGQPPHMRRQGPPHINHDDPSLVPNVPYFDLPAGLMAPLVKLEDHEYKPLDPKDIRLPPPMPPSERLLAAVEAFYSPPSHDRPRNSEGWEQNGLYEFFRAKMRARRRKGQEKRNSGPSRSRSRSKSRGRSSSRSNSRSSKSSGSYSRSRSRSCSRSYSRSRSRSRSRSRSSRSRSRSQSRSRSKSYSPGRRRRSRSRSPTPPSSAGLGSNSAPPIPDSRLGEENKGHQMLVKMGWSGSGGLGAKEQGIQDPIKGGDVRDKWDQYKGVGVALDDPYENYRRNKSYSFIARMKARDECKLast
1 -188.000[R] KOG4368 Predicted RNA binding protein, contains SWAP, RPR and G-patch domains  ali  100  1MTMEKQKDNPKFSFLFGGEFYSYYKCKLALEQQQLICKQQTPELEPAATMPPLPQPPLAPAAPIPPAQGAPSMDELIQQSQWNLQQQEQHLLALRQEQVTAAVAHAVEQQMQKLLEETQLDMNEFDNLLQPIIDTCTKDAISAGKNWMFSNAKSPPHCELMAGHLRNRITADGAHFELRLHLIYLINDVLHHCQRKQARELLAALQKVVVPIYCTSFLAVEEDKQQKIARLLQLWEKNGYFDDSIIQQLQSPALGLGQYQATLINEYSSVVQPVQLAFQQQIQTLKTQHEEFVTSLAQQQQQQQQQQQQLQMPQMEAEVKATPPPPAPPPAPAPAPAIPPTTQPDDSKPPIQMPGSSEYEAPGGVQDPAAAGPRGPGPHDQIPPNKPPWFDQPHPVAPWGQQQPPEQPPYPHHQGGPPHCPPWNNSHEGMWGEQRGDPGWNGQRDAPWNNQPDAAWNSQFEGPWNSQHEQPPWGGGQREPPFRMQRPPHFRGPFPPHQQHPQFNQPPHPHNFNRFPPRFMQDDFPPRHPFERPPYPHRFDYPQGDFPAEMGPPHHHPGHRMPHPGINEHPPWAGPQHPDFGPPPHGFNGQPPHMRRQGPPHINHDDPSLVPNVPYFDLPAGLMAPLVKLEDHEYKPLDPKDIRLPPPMPPSERLLAAVEAFYSPPSHDRPRNSEGWEQNGLYEFFRAKMRARRRKGQEKRNSGPSRSRSRSKSRGRSSSRSNSRSSKSSGSYSRSRSRSCSRSYSRSRSRSRSRSRSSRSRSRSQSRSRSKSYSPGRRRRSRSRSPTPPSSAGLGSNSAPPIPDSRLGEENKGHQMLVKMGWSGSGGLGAKEQGIQDPIKGGDVRDKWDQYKGVGVALDDPYENYRRNKSYSFIARMKARDECK 884
2 -27.600[R] KOG0151 Predicted splicing regulator, contains RRM, SWAP and RPR domains  ali follow..  11  338AIMERGRGNPLFNFLFGSKEHTYYVWRLYSFAQGDTLQRWRTEPYIMIAGSGRWIP--------------PPLPATRSPEHGKESRGTYAAGKSRCTEAEQTLTDSQR--------------DEFEDMLRAL--TLERSQIREAMGFALDNAEA---AGEVVEVLTESLTLKETSIPTKVARLMLVSDIIHNSSAKNASAYRTKFEATLPDIMVHGRITAEYFVQERVLKVLQVWADWFLFSDAYINGLRATFLRSRNFGVTSFHSICGDAPDIEKKGLIGNMNDADKINQDAALAMGEGAARQELMNRPISELERRCRHNGLSLLGGREMMVARLVCLKDAEKQRGYEVVDENAKYRQGHSTWEEVNIEPKRMKTSYDKVETEEPVDLASTIPIPQPELKAFVKKEKIDLILPTSRWAREDDETDDEQKKSYSSGSDNAGGITFKTDEEDLKADPSVRVQPENEIDVE----------------------------------------------------------------------------------------------------------------------------------------------------------------QRQKLRHIEIALIEY------RESL-------------EEQGMKNSEEIERKVAIHRKRLEADGLSGNQRVLPEKREKREDSRDSSRKRNRSESQNRSQSPPQKSLTRERVRDHDLDKDRHRDRDRQQHDLDKDRKRRAKSSSRERDDHDRSRERDRDWRRRGM........................................................................................... 956
3 -20.900[A] KOG2669 Regulator of nuclear mRNA  ali follow..  10  2....................................................................................................................SSPFSEEILIDNLAKLNS--TQQSIQTLSQWCIVHRS---EAELVVTTWEKQF--HSTQIGQKVPLLYLANDILQNS-KRQGNEFVQEFWKVLPGALKDIVSLGDDYGKGVVSRLVNIWEERRVFGSRSKSLKDVMLSEEAPPPLDVSKKRFRGSKSAKRDSKEKLKSVEESRTSLVNHLREALREQESELENLQSQIQVAQEQTEEAQNMQKRLNNETPVNNNNGTSGQSAKITPASIAAMAEMLTSSTNSSMIMHSVLSSFAAEATQTSGLTKSNTSDTNAFVVPPNPQQYHIIPNPAASQQFPYGFGNIPLMPPGALPPPPPGTLPPHMMNNNNQPNAAQQQAQQGQSFHPPGMMYFGPPHHS.................................................................................................................................................................................................................................................................................................................................................................................................................. 439
4 -16.600[R] KOG0154 RNA-binding protein RBM5 and related proteins, contain G-patch and RRM domains  ali follow..  15  747...................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................KRAFSDVEVLRKHVEKSDLHRNNLEAKRAEWGRETAAKLQEEEEDASAPDLPKIVYRDRAKERRRQFGIDSTGYAFDVMGGPPGPTSVRHEETIRKVSE----------EASKRPLDESNIGNRLLKSMGWKEGQGVGKHAQGIVNPIEA----ERFVQGAGLGAA-HGAEASHKEK------QALYSRYHD. 924
5 -15.600[A] KOG2184 Tuftelin-interacting protein TIP39, contains G-patch domain  ali follow..  12  2................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................SLSHLYRDGEGRIDDDDDERE-----NFEITDWDLQNEFNPNRQRHWQTKEEATYGVWAERDSDDERPSFGGKRARDYSAPVNFISAGLKKGAAEEAELEDSDDEEKPVKQDDFPKDFGPRKLKTGGNFKPSQKGFAGGTKSFMDFGSWERHTKGIGQKLLQKMGYVPGRGLGKNAQGIINPIEA-KQRKGK---GAVGAYGSERTTQSMQDFPVVDSEEEAEEEFQK 220
6 -12.800[A] KOG4849 mRNA cleavage factor I subunit/CPSF subunit  ali follow..  15  100.......................................................................................................................................................................................................................................LTWWTT----DQDIANSLRD-EVKFFENRANGQSKGFSVISLGSESSLRAVLDQLPKKE---------MHGQAPVVTYPSKQALTQFESLQKTRPVPPPQQNGPPRGPAPPSMGGGPMPTGHPGGPQGGGPPGHPPRGMNSIMQPGQYRPQHMSQVPQVGGPNSGPPRMQPPMHPQGGLMGNQQPPPRYPSAQGQWPGQRPGGPRPGPPNGPPQRPMFQGGPMGMPVRGPAGPDWRRPPMHGGFPPQGPPRGLPPAPGPGGPHGA---------PAPHVNPAFFNQPGGPAQHPGMGGPPHGAPGPQPGMNMPPQQGMNMTPQHGPPPQFAQHGPRGPWPPPQGKPPGPFPDPQQMGPQLTEVEFEEVMSRNRTVSSSAIARAVSDAAAGEYSSAIETLVTAISLIKQSKVRCKILISSLQDTLHGIEA-YNRRERSRSRERS-----------HRSRQRRERSTSRYRERSRERERDRDRERERDGGRSVRPRKSPEPVVAEAAEAPSSKRYYEDRERYRSSDRERRDRDRDRDRERERDRDRHFTNDGRGLPLDPSNFTSQNPGNIKTGRPKSAAVAGGSME---------------PRGQSAWDIIDTDAHWIKQQTTSIPAPPSSQ-QNFN.................. 698
7 -11.600[R] KOG2350 Zn-finger protein joined to JAZF1 (predicted suppressor)  ali follow..  10  527.................................................................................................................................RLYHHTETCLPVHPKELWLRQKTI-------------QMIDEFSDVNEGEKELMKLWNLHVMRHGFVGDCQLPIACEMFL-----GTEIVRKNLYRNFILHMCSLFD-YGLIAAETVYKTVQKLQGLLSKYAAGQELMQRQREEQLKYWLDVGMHKKQEDPKTLKSPQKPAPPADQASTSSASTSGSGSGSSSMQPPKRMPAHLKRGSAASSPGVQSKGTENGTNGSNSSSSNSKNVAKKSADQPLSTLANTRERRSEYGQKRNVSGSRLAATPASKRKLSSKDVEQAADAPEVLTHSDNAVDVGIIDDECGGFGAVGVMNGVASPVANNSEMDTEAEVEAEPTATKAITIHCQQPVTTPVAAAATANERLPG--VAPHRRGPRRADRREEELVASAPGYRCRPSMRGADAGAAAAAAAAPTHPHPHRPPPPPPP................................................................................................................................................................................................................................................................................................................................ 954
8 -10.500[K] KOG2181 LIM domain binding protein LDB1/NLI/CLIM  ali follow..  9  6...........FKFLFGNNQHG-YRIQIVIFFRAIHIMMFHRPPSARPPLNHVDQLKSLQATALGKPGMRSQA--------------------------------TEPQPIGNTVSPLEFRIHDMNRRLYIFSSTGVSEN-DQQQWWFFDDDCKSRERYIINRQFIPKFF--RSIFDSGMRELQYVGSQAYEN--ENVLQITRYDQSSQFEVNTEGKLYVEFAPFDEVMNYIKAWRSNEFVYNQNTADYRVEAQNPEQENKPRMGFFKSTFNLMTMLKILDPMQSIMSSAKSAPAITPREVMKRTLFQHHQVRQQNMRQQQLNQQMMIPAPEPEKPKPARKRQRKPAANPRGSKKATAAAAAAAAAATNGVPPTVPTASPANNQQFPPNPMTSQFQQMSYPDVMVVGEPSMMGSEFGENDERTISRVENSQYDPNAMQMQSLGQGPNSSMNINGRNMMNQHHPGMQPPPGQQHMPPHSMGSQMPTSMHNPMHMPPGSMQGHGGMPPMPSTMANQMPPPNLPPHTMSNQMPNSRMPPMQGQMPPSGMPGQMSNPNMMGSGMPPMSMSSQMPGSMSNPMPNQMPGGMQMNQMPPPNYSQYTGGPPPQWPPPNSAMI.............................................................................................................................................................................................................................................................................. 627
9 -9.980[A] KOG2185 Predicted RNA-processing protein, contains G-patch domain  ali follow..  12  176..........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................EWKQLMVGSKIWAVSGSKYDIWRKAELESWDDELQVGGVVFRDDKSSAKLGSDSLALSEYAQMTDDDGEEEEEEDEQQSASDSEDSVSSDYDEGSPQGIGFLESTNLPRGVQTDTALFAKWE--NHTRGIASKMMASMGYREGMGLGVSGQGILNPILV-KVLPA----RSLDYGECKSEKQKKKRSRGGKRKRGKKFAEAA 378
10 -9.920[A] KOG1994 Predicted RNA binding protein, contains G-patch and Zn-finger domains  ali follow..  14  2.................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................SDDEDDYMSAEILQGVSEQPVGIAKSRAHKRELQINSRFEESRDTFKPKRPTSHAEREKERRDEALAKPISHESKGFALMAKMGFKPGMTLGKQREDEIRITEPIGVDIKANR-KGLGHEVEAV-AAKHEELIDDYSKRRKLDANSK 163
11 -9.770[AD] KOG2809 Telomerase elongation inhibitor/RNA maturation protein PINX1  ali follow..  29  25.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................DDSKFGQRMLEKMGWSKGKGLGAQEHGATDHIK---VQVKNNH-LGLGAT-QDDFNQLLAELNTCHGQETTDSSDKK 106
12 -9.760[R] KOG4307 RNA binding protein RBM12/SWAN  ali follow..  13  7................................................................................................................................LKNLPMTAGASDVRT----FFTGLK-----------IPDGAVHIIGGDEGEVFVGFSSDDDARLAMTKD----RLMIHGAEVRLFLSS--------KSEQNSVIA--RKNNTYTSPVYKEYVPPVPSQPTPAQEQNWNSQTAGNPYAAKAGYEASYPPQNSNATRTSFNNQNSYSNRQEISQNHQENSVKLKDPFGGDYGGYKFQQQPPPQINRYGSGPPPSKPADLSNTRSLPPVNNPPPPHPIPQFPPEKQFGNKLGNNNDVSSRENHIQGSGNERVQGGDSWRDTSFNQPPRNDFKGNYNNAYSSNKYKNNYKAPEFNNDFNGGNKFNQFPPRNAQSTDLSENRAAPPQTGRKTLMPTPQAPFQNAPAPFTNGPSDDVNRPFQTGPPGNLGRNGPPPFQAGVPPPVIQNNMGRPIAPPAAMVRPPPQNFPGGAGGALPVFQAPVMTPIVPPVNKPMGAAAVEK----------------------RLPTDLLRPAA--------PLTLSSVKT-----PGGIHMHTIIRLDSIADYATMMRRNG-------EQGIKIQQSDKKSFDTAIDGIPIPSVSMVPSKEQRSHEDDDKKSRRSRWENTSPIRSPRRSPLRRDNRDRSRSRSPPRRRRRSRSPRRREEHTDPTR-----------------------------------QV----------------TNVPFRMKDEELLE---TFYSDGNASDRWVAEFSSESLMKRSFGIRTLCTGR 672
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Li W, Godzik A. cd-hit: a fast program for clustering and comparing large sets of protein or nucleotide sequences. Bioinformatics. 2006 May 26;