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Query: [R] KOG4433 Tweety transmembrane/cell surface protein, from COG1018

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MKPTNNKLQCQQKGIELQSLVILASIPAGLLIGSLLGLLLYLLTRCCDRRQRKPSAQRCQSCSLVIITLMTCAAIGLGLYGNDDFHNGLLQAFGSGKSVEGLVLTLKRQTESIKHDLETRMAGHKVEQLVEKPHYNQTVVMLLIETSRLVTENTSRAVASLDSMVHYFMKAKGSENDTSLMGLLQLGEFYESIRWPATLAFLTVLLLLCTVLVIGVARRSRCTLIFFSVSGLFCIIICWLLAGVYLASSVAAGDFCMRPHDYMCRQVGMRSPYVDFLNCGTPRNRFILRLNESRDLVDRARESVEHMQRMSQETYPHIDIQRTLNAMDNDLEITLRNLTTLSATLDRRTIDMHYEEALRGLCGGGLLGLSLMMVAGLLTSFLLTILVYADSHAWIYLTKRPTLDADKSETAPLFPASNAPSASISPTAPLSTGTINRTLLHHQQASSGGGSGTLPGSGGGAGAGGGVGANGHNGVGPYRNGSAGLRQGLASPSSQSSHTSSTATYNNGTTSYHNSHQQHNNHLYSNHYSHSNNHYNNTQHRTNPAAGAVAAAVGVVSSGQRSPSPPPVYDLDAFHRTTSNRRRICQDPTMESSSSNTAQQQQQNLQLQQHQQQSNLINQNQSQSTLKNIFASATLPRSTGSSIRSVLSVQTSNAGICRSTGNGLDGDMVDDRDPRDVTNNSFNRFDPKYISIGPKAVRGQNNNLNIMSVAGGANKCATLRHVGRYGGSLKGVSAVNATPSPAAAPAVHSPNLRSAKTPSIATVSKDYCLast
1 -129.000[R] KOG4433 Tweety transmembrane/cell surface protein  ali  100  1MKPTNNKLQCQQKGIELQSLVILASIPAGLLIGSLLGLLLYLLTRCCDRRQRKPSAQRCQSCSLVIITLMTCAAIGLGLYGNDDFHNGLLQAFGSGKSVEGLVLTLKRQTESIKHDLETRMAGHKVEQLVEKPHYNQTVVMLLIETSRLVTENTSRAVASLDSMVHYFMKAKGSENDTSLMGLLQLGEFYESIRWPATLAFLTVLLLLCTVLVIGVARRSRCTLIFFSVSGLFCIIICWLLAGVYLASSVAAGDFCMRPHDYMCRQVGMRSPYVDFLNCGTPRNRFILRLNESRDLVDRARESVEHMQRMSQETYPHIDIQRTLNAMDNDLEITLRNLTTLSATLDRRTIDMHYEEALRGLCGGGLLGLSLMMVAGLLTSFLLTILVYADSHAWIYLTKRPTLDADKSETAPLFPASNAPSASISPTAPLSTGTINRTLLHHQQASSGGGSGTLPGSGGGAGAGGGVGANGHNGVGPYRNGSAGLRQGLASPSSQSSHTSSTATYNNGTTSYHNSHQQHNNHLYSNHYSHSNNHYNNTQHRTNPAAGAVAAAVGVVSSGQRSPSPPPVYDLDAFHRTTSNRRRICQDPTMESSSSNTAQQQQQNLQLQQHQQQSNLINQNQSQSTLKNIFASATLPRSTGSSIRSVLSVQTSNAGICRSTGNGLDGDMVDDRDPRDVTNNSFNRFDPKYISIGPKAVRGQNNNLNIMSVAGGANKCATLRHVGRYGGSLKGVSAVNATPSPAAAPAVHSPNLRSAKTPSIATVSKDYC 768
2 -15.200[R] KOG4331 Polytopic membrane protein Prominin  ali follow..  11  99...............FQKGWIVLSVGLVAISVLFVVFYFFYKCCVCICSQNTDARYDGCKRLLLFVLVSANAFVAFTLLMTSQYAQIGLDKLPNRMDDYQVLNSTITKQLSTAGYNVVDRVKKLTGAHVIDVFMNISKVAQEMHDGLESVHGKVRFLNEEGSRFEAEFSRLRNTANEEVSDPKKTPTLKYMQYSWYASLVITSLFILLALIFLFGVLTGGKFYSFGIGAFLLIFVFLAVGTSALMFAVGNFSNLVCRNPLSHIEVTLQSKSPAEIIRACSRNETLYNREFEESLDANSGRPKAVTLVLEQIRELEIQTSLDEKLSQLQVPVSSLLVKLQHAQALLACQPLTQIARQTTAAVCAYTIDPYNGTWMCMLICLVLLIPIVIISNSLIGLYSKMHAFPKYIVEPPSETHHMSSFITDTYDTRPKPGYANYTYTDDYQRN................................................................................................................................................................................................................................................................................................................................... 864
3 -9.340[TU] KOG3895 Synaptic vesicle protein Synapsin  ali follow..  10  581...............................................................................................................................................................................................................................................................................................................................................................................................................................LGKQFSFAGKGEGVISTQPTQRPSEEPPAIPTTASSAVRPESSVSVSDSRNTDTLTERAGAGYQPVTNYEQQERVNPFDKEPSKSGSAASIHTSSSSSISSSSISSRINRNGNAIQSPPPPAGPPPPPPTNVTAVGSNANSSSGYRNSFSSSLSKDKTSYGNYGSTTSVETITRMDTNTTNIGATATEAGEASGVTAITNISNSDGIVAPTTGTITTSVTTNDWRSAIGMRSASVYSAPAAVTTVLPGDTSGYDSNSIASQGEGLNNPSDLPSYTRPSYSRSESNASKGDSKTTPASYGNGKYTRAAGSISDADMIFGGPPSNYKTDRFGASKSMSMTSGGVGSGNGSGS... 938
4 -9.280[K] KOG2150 CCR4-NOT transcriptional regulation complex, NOT5 subunit  ali follow..  6  9.................................................................................................EVDRVFKKINEGLEIFNSYYER------HESCTNNPSQKDKLESDLKREVKKLQR---------EQIKSWQSSPDIKDKDSLLDYRRSVEIAMEKYK---------------------VEKASK--------------EKAYSNISLKKSETL-------DP-----QERERRDISEY----------LSQMIDELERQYDSLQVEIDKLLLLNKK--SSTTNDEKKEQYKRFQARYRWHQQQMELAL--RLLANEELDP------QDVKNV--------------------DDINYFVESNQDPDFVEDEDGLNLQSNEAIAHEVAQYFASQNAEDNNTSDANESLQDISKLSKKEQRKLEREAKKAAKLAAKNATGAAIPVAGPSSTPSPVIPVADASKETERSPSSSPIHNATKPEEAVKTSIKSPRSSADNLLPSLQKSPSSATPETPTNVHTHIHQTPNGITGATTLKPATLPAKPAGELKWAVAASQAVEKDRKVTSASSTISNTSTKTPTTAAATTTSSNANSRIGSALNTPKLSTSSLSLQPDNTGASSSAATAAAVLAAGAAAVHQNNQAFYRNMSSSHHPLVSLATNPKSEHEVATTVNQNGPENTTKKVMEQKEEESPEERNKLQVPTFGVFDDDFESDRDSETEPEEEEQPSTPKY... 584
5 -9.120[R] KOG2893 Zn finger protein  ali follow..  8  1.......................................................................................................................................................................................................................MGRKKKKQL--------------W----------------C------------------WY--CNRD---F-----DDEKIL---------IQHQKAKHFKCHICHKKLY-----------TGPGLA--IHCMQVHKETIDAVPNAIPGGMEGI-------------------MDERRRLLEQKTQESQKKKQQDDSDEYDDDDSAASTSFQPQPVQPQQGYIPPMAQPGLPPVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPGMPPGMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTATVPAPQPPVTKPLFPSAGQMGTPVTSSSTASSNSESLSASSKALFPSTAQAQAAVQGPVGTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSATSKLIHPDEDISLEERRPRPGQAPIGNPPVGPIGGMMPPQPGIPQQQGMRPPMPPHGQYGGHHQGMPGYLPGAMPPYGQGPPMVPPYQGGPPRPPMGMRPPVMSQGGRY. 478
6 -8.920[R] KOG2350 Zn-finger protein joined to JAZF1 (predicted suppressor)  ali follow..  7  650...........................................................................................................................................................................................................................................................................................................................................................................................................................................................SKYAAGQELMQRQREEQLKYWLDVGMHKKQEDPKTLKSPQKPAPPADQASTSSASTSGSGSGSSSMQPPKRMPAHLKRGSAASSPGVQSKGTENGTNGSNSSSSNSKNVAKKSADQPLSTLANTRERRSEYGQKRNVSGSRLAATPASKRKLSSKDVEQAADAPEVLTHSDNAVDVGIIDDECGGFGAVGVMNGVASPVANNSEMDTEAEVEAEPTATKAITIHCQQPVTTPVAAAATANERLPGVAP--HRRGPRRADRREEELVASAPGYRCRPSMRGADAGAAAAAAAAPTHPHPHRPPPPPPPQ................. 955
7 -8.830[R] KOG3253 Predicted alpha/beta hydrolase  ali follow..  7  7................................................................................................QKARSVMNECERHVIFARTDADAPPPPEDWEEHVNRTGWTMAQNKLFNKILKALQSDLARLANEGACNEPVLRRVAVDKCARRVRQALASVS--KLIQWLHTTLVLSLPMLAAYLDALQTLKGKIPTLIDRMLVSALSLLLK-------------------DPAVGVLSHNKPSKL--LILIASSGPSSSVFPTSRRHRFWQSQLSCLGKVIPVATHLLNNGSGVGVLQCLEHMIGAVRSKVLEIHSHFPHKPI------ILIG--MEYVTAVVCL-LLDMKTPVLFVILVVVGG-----LTQSMVDRCIQDEIVDFLTGVLTRAEGHMGSEPRDQDAEKKKKPRDVARRDLAFEVPERGSRPASPAAKLPASPSGSEDLSSVSSSPTSSPKTKVTTVTSAQKSSQIGSSQLLKRH-VQRTEAVLTHKQAQVPISSEPPEEGEKEDLRVQLKRHHPSSPLPGSKTSKRPKIKVSLISQGDTAGGPCAPSQGSAPEAAGGKPITMTLGQASAGAKELTGLLTTAKSSSSEGGVSASPVPSVVSSSTAPSALHTLQSRLVATSPGSSLPGATSASSLLQGLSFSLQDISSKTSGLPANPSPGPAPQATSVKLPTPMQSLGAITTGTSTIVRTIPVATTLSSLGATPGGKPTAIHQLLTNGGLAKLASSLPG... 731
8 -8.600[K] KOG2181 LIM domain binding protein LDB1/NLI/CLIM  ali follow..  8  1...............................................................................................................................................................................................................MCVVIFLGRLAQS------YRIQDLLFIIVIFFRA-LYIFSSTGVSE-----DAFSHEFFDDDCKLWFVIGSEPVAFASRERYIINRQFIPK---------------FFRSIFDSGMRELQYVLRGPSRECTLANGAYENENVLQITRYDQSSQFEVNTEGKLYVEFAPFDEVMNYRI------KAWTLELKRSNEFVYNQNTADYRVEAQNPEQENKPRMGFFKSTFNSSAKSAPAITPREVMKRTLFQHHQVRQQNMRQQQLNQQMMIPAPEPEKPKPARKRQRKPAANPRGSKKATAAAAAAAAAATNGVPPTVPTASPANNQQFPPNPMTSQFQQMSYPDVMVVGEPSMMGSEFGENDERTISRVENSQYDPNAMQMQSLGQGPNSSMNINGRNMMNQHHPGMQPPPGQQHMPPHSMGSQMPTSMHNPMHMPPGSMQGHGGMPPMPSTMANQMPPPNLPPHTMSNQMPNSRMPPMQGQMPPSGMPGQMSNPNMMGSGMPPMSMSSQMPGSMSNPMPNQMPGGMQMNQMPPPNYSQYTGGPPPQWPPPNSAMITG... 629
9 -8.380[O] KOG0802 E3 ubiquitin ligase  ali follow..  8  19..................GLQVWTELSLDRLRADGLIALELLL--------GSYFTIALLTNFVLNVYILLVLSLKTLFFGD------------YDVETKKLVERLANYIIYKGTFLPLVIPPTIFQGVL-------TVWLTVLCTLKMFQALARDRLERLNA--------------------SPSSTPWTYFRVYSVLFLVLSVDMFWIKLSLMTYNTIGSAVYLLLLFEPCSIAFE--TLQALLIHGFQLLDMWINHLGFFLDMATLVMALGHYLHI------WLHGIAFHLVDAVLFLNIRALLSAILKRIKGYIKLRIALGALHAALDATSEELRAYDDE--C------------AICREPMAKAKRLHCNHLF-------LGCL--RSWLDQGLNEV------YSCPTCRKP-VGRTENEVNPRTVEVSSDEQLARQLERQNNPVHALATGLFPAEVPDSVENDTSRNLGLDPSWLQTWSSQGSDVAGPSTTSRTVGLGRVQMMMRHLASVGESYAQTALDDAAWSLWPMNPSQASTSSTTVPPGNGGRTGGLHLRTVSNTTNESLTNILAMAETVREVMPHVPDEIIFQV............................................................................................................................................................................ 585
10 -8.160[K] COG5576 Homeodomain-containing transcription factor  ali follow..  8  444...............................................................................................................................................................................................................................................LVIGLWKRLRASPQDLCF--------YSPPKKLFAYLIQ--FQGIQYRIEYS-ESIHVFRVEEPLLNELSATASSRDKPAPNEYWLQMDIQLSVP---MITSEGQGNC----TDFTEGNQAVLLHSLMGRATSMFQMLD---------------------------RVRRASPELGSVIRLQKGLNPHQFLDPQWANQLPRQPDSSVFDHQGRNPPIQGLSHDTSSEYGNKSQFKRLRSTSTPARQDLAQHLLPPKTNTEGLMHAQSVSPITQAMKSANVLEGSSTRLNSYEPSVSSAYPHHNLALNLDNTQFGELGTSNISYPLSAPSDVGSLPRASNSPSRPVMHPNTQGINTEIKDMAAQFPNSQTGGLTPNSWSMNTNVSVPFTTQNREFGGIGSSSISTTMNAPSQQLSQVPFGDVSLATENSVPSYGFEVPSEESVYAQARTNSSVSAGVAPRLFIQTPSIPLASSAGQDSNLIEKSSSGGVYASQPGASGYLSHDQSGSPFEDVYSPSAGIDFQKLRGQQF. 937
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Li W, Godzik A. cd-hit: a fast program for clustering and comparing large sets of protein or nucleotide sequences. Bioinformatics. 2006 May 26;