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Query: [S] KOG4619 Uncharacterized conserved protein, from COG1018

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MISSPARLAFAMIGRASSRTLLTNHSVTSIRLSTTAAFKHLDKLIIETPNDAMEIASRLTIIEQQMLKSALDDCLTKKEDGKVEELTQEQVKGIFLVNSIPFIGFGVLDNMIMILAGEYIDQKLGAVLAISTMAAAALGNLISDIAGVGLAHYVEVAVQRVGIKHPVLTSQQLDSGKARFTTNAARAAGLTVGCLLGMFPLLFFSDDEDDEKKKKKELKATKLELast
1 -84.300[S] KOG4619 Uncharacterized conserved protein  ali  100  1MISSPARLAFAMIGRASSRTLLTNHSVTSIRLSTTAAFKHLDKLIIETPNDAMEIASRLTIIEQQMLKSALDDCLTKKEDGKVEELTQEQVKGIFLVNSIPFIGFGVLDNMIMILAGEYIDQKLGAVLAISTMAAAALGNLISDIAGVGLAHYVEVAVQRVGIKHPVLTSQQLDSGKARFTTNAARAAGLTVGCLLGMFPLLFFSDDEDDEKKKKKELKATKLE 224
2 -9.210[T] KOG2289 Rhomboid family proteins  ali follow..  16  114..........................................................................................LSCMWLHAGIIHLLTNML---SLIFIGIRLEQQFGFIVGLIYLISGLGGSILSALFGLLGAMLSELLTNWTIYANKAIIAINLALGMLPRVDNFAHIGGFLTGFCLGFVLLVRPQYGWEASRTNTSRTKRKYS. 266
3 -8.890[T] KOG2290 Rhomboid family proteins  ali follow..  19  657..........................................................................................WLSLFLHAGILHCLVSIC---FQMTVLRDLEKLAGWHIAIIYLLSGVTGNLASSQFGILACLFVELFQSWQILARPAVVLFLFTFGLLPWIDNFAHISGFISGLFLSFAFLPYISFGKFDLYRK.......... 800
4 -8.180[S] KOG4473 Uncharacterized membrane protein  ali follow..  9  2........................................................................ESNNNNLNLDMEKDQETTFDYSKRAQWLRAAVLGANDGLVSTAS--LMMGIGAVKQDVRIMLLTGFAGLVAGACSMAIGEFISVYSQY--MKRESGGETKKEKLPSPTQAAIASALAFTLGAIVPLLAAAFVKEYK................ 139
5 -7.610[T] KOG2980 Integral membrane protease of the rhomboid family involved in different forms of regulated intramembrane proteolysis  ali follow..  12  187..........................................................................................IGSAFSHQEFWHLGMNML---ALWSFGTSLATMLGASNFFSLYMNSAIAGSLFSLWSLGASGALFGVLGCFSYLFPHAAGCALRWGSFDYAAHLG-------GSMMGVLYGWYISKAVEKQRQRRLQ....... 340
6 -7.420[M] COG1970 Large-conductance mechanosensitive channel  ali follow..  13  1........................................................................................................MSIIKEF-FAMRGNVVDLAVGVIIG------AAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAA.... 111
7 -7.310[C] KOG3196 NADH:ubiquinone oxidoreductase, NDUFV2/24 kD subunit  ali follow..  16  2............LTNCASKTLAAVRANIRAIATSSARASDNLFVHRDTPEDNPNIPFEFTAENKKRVEAILSIYPEGHKRG----------------AMIPLL-YGWLPISAMHKVAEILQLPNMRVYEVATFYTKPTGKYHIQVCT-GSDDILETCKKQLGIGVGDTTKD-------------RKFTISEVECLCVNAPMVAINDDYYEDLTSKD........ 193
8 -6.950[R] COG0705 Uncharacterized membrane protein (homolog of Drosophila rhomboid)  ali follow..  21  139..........................................................................................FTHIFMHFSLMHILFNLL---WWWYLGGAVEKRLGVITVISALLSGYVQQKFSGPWFGGLSGVVYALMGYVWLRGERDPQSGIYLQRGLIMANGAHIAGLIVGLAMAFV......................... 267
9 -6.770[MU] COG0597 Lipoprotein signal peptidase  ali follow..  12  56......................................................................................................AAFSFLADTLVVMMYRSKATQKLNNIAYALIIGGALGNLFDRLWHGFVVDMIDFYVGDWHFATFNLAD-----------------TAICVGAALIVLEGFLPSKAKKQ.............. 164
10 -6.770[S] COG0398 Uncharacterized conserved protein  ali follow..  12  56..........................................................................................IQSYGALAAVVSFLLMILQAIAAPLPAFLITFANASLFGSLSWTSSMAGAALCFFIARVMGEVVEKLTGKTVLDSMDGFFTRYGKHTILVCRLLSYAAGLTIATGLGQLPATIV.................... 191
FFAS is supported by the NIH grant R01-GM087218-01
1 4 6 8 3 2   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Grynberg M, Erlandsen H, Godzik A. HEPN: a common domain in bacterial drug resistance and human neurodegenerative proteins. Trends Biochem Sci. 2003 May;28(5):224-6. Review.