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Query: [S] KOG4647 Uncharacterized membrane protein, from COG1018

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MGEQGEETGQKLTERSTKEAYFESLAEWAKQATLAQNAMLMFPYYLMANYPTMFPGLPSSAALQAAAMGQPQALVQGSAAAPGEPAAEPRLPAPNFSGLRILGEAAQLDIIQRLGGYEYVLSPFWKRAVAETIDMFILFIVKIIITFGVVNLFNIEFDEDVIRRTLDQEDLFSNFFDTSLDFISMSTDLLLIEMLTKFIVCCYEALWTYLYQGATPGKSLMKIRIYYVEAVMPLQGPPLPQFVLQPQREPMRALLYPPQTPSLMRSFARALIKNLGMTLLFPICVLMVFFKNNRTAYDVLTKTIVVESNSIAVFRTQGQAQRNNRLast
1 -118.000[S] KOG4647 Uncharacterized membrane protein  ali  100  1MGEQGEETGQKLTERSTKEAYFESLAEWAKQATLAQNAMLMFPYYLMANYPTMFPGLPSSAALQAAAMGQPQALVQGSAAAPGEPAAEPRLPAPNFSGLRILGEAAQLDIIQRLGGYEYVLSPFWKRAVAETIDMFILFIVKIIITFGVVNLFNIEFDEDVIRRTLDQEDLFSNFFDTSLDFISMSTDLLLIEMLTKFIVCCYEALWTYLYQGATPGKSLMKIRIYYVEAVMPLQGPPLPQFVLQPQREPMRALLYPPQTPSLMRSFARALIKNLGMTLLFPICVLMVFFKNNRTAYDVLTKTIVVESNSIAVFRTQGQAQRNNR 325
2 -60.500[S] COG1714 Predicted membrane protein/domain  ali follow..  16  2..........................................................................................SFLTLKGNKMIIENQKDAEFSSAFKPSQLAQASRFKRWLASMINGLVLWVMAGLGFA-----------------------------------------LGDFAGVVGMIVYAGFQLYFMKTYGQTMAKRWLGLRVFNYHT---------------------------NQPVEFGKYIGREIIDILLAWLLIISGIVALVRDDRRSLTDLVAGTIVLKDEK............... 156
3 -10.400[O] KOG0317 Predicted E3 ubiquitin ligase, integral peroxisomal membrane protein  ali follow..  11  2....................................................................................................KNDNKLQKEALMRLSQLRFPFADAPSIVQAHQKDEQIQGLLIMKVTELCKLIKSQLFVNSYPKE-------------------------------LSIFAKLLYLLFTTGRRGRTLGEEYVDLTYTNRKGTRLAGRLKMIVFAFAYPLCPYFITKLYKKIMKNNKESKIAFCKGLLDFILDVHMTLFYFKGAFYSISKRIFGMRYVFKHILSKNEAN........ 194
4 -8.910[O] KOG0826 Predicted E3 ubiquitin ligase involved in peroxisome organization  ali follow..  10  15.........................................................................................................................PSIFEISASETLDNLIYPALSKIFDYFG------------------------------LRLDFKLWGSLRIQEELSPLLTWLLQYLYLRKRASSFGESFYGLQRTVTTTGDLLNRRQQFASATLLTFMPLRTRITRHEDTSPWEQRLLSAFHAFHAAKAAHTFFYLVKYASNHSPIFRLLGLTLRYPSEPPKED.......... 183
5 -8.160[S] COG5413 Uncharacterized integral membrane protein  ali follow..  6  9.......................................................................................................ADSGATIMRESTSVNPTYQGQFGPFTVNDHDRREVILYRTGLALAAGGFSLGVALALAQPFQPLAVNFHLATACFWLMTGGLGLSLWTIHIYLAVLHRTLQIFWAIGTTAAGIGFTFAALTGIFFKEA----------FCFNRLETKFLTAIIPLLLLGHLAGILPLTVAKGGLVSASVLFLIFVARKVMQPLDPDIGDKSVFTYLAEQRKAAQS....... 236
6 -8.110[S] COG4125 Predicted membrane protein  ali follow..  14  1........................................................................................................................MRSLQDRIRALSFEIIGLMLVIPLGALLF-----------------------------GMPMEDIGIVGLVSATLATVWNYVYNLGFDHAMQRLKG-LKTPAIRVAHAVLFELG----------------LLIVLMPFIAWYLNISLVHALVMDISFALFYVVYAFVF-----NWSYDRI......................... 132
7 -8.100[S] COG4241 Predicted membrane protein  ali follow..  5  96..........................................................................................................................SPFAVLLGGSLSNIAWVLLLFISSIVIMDVNPLVAAQETMRQSMQTAEQLIIGLGQEPSEALKQMEESINQLFYLGPAMVVICGTLLAAVTQLVAAPILKRLRHEVKPLPPFRTWSFPRSFLFYYLAVVVLFMIGFEEGSMPYIAVWNLLPVLEIIMAIQGFAVIFAYFHTKGVAKAVPVIIMI................... 279
8 -7.660[O] KOG2879 Predicted E3 ubiquitin ligase  ali follow..  9  2.........................................................................................TPSTPADDAWIRSYQRLLPESQSLLASRRSVIPVAISRV-AARLDVEMSAMLKEQLVKVFTLMKPGMLFQYEPE--------------------------------LDAFLEFLIWRFSIWVDKPTPGNALMNLRYRDERGVVAQHLGKGLEGPGLTSPQKIWYCVASSEQRPLARRLWTLVIEGIYKAASFLNLLSFLYTGRYRNLIEKALKARLVYRSPHMNRS.......... 221
9 -6.700[S] COG4811 Predicted membrane protein  ali follow..  7  1......................................................................................................................................................................................MTITDLVLILFIAALLAFAIYDQFIMPRRNGPT----LLAIPLLRRGRID------------SVIFVGLIVILIYNNVTNHGALITTWLLSALALMGFYIFWIKIIFKQKGKAMNLSEDGVLVMQLEQRRLLIRVRNIDDLEK 143
10 -6.670[S] COG2456 Uncharacterized conserved protein  ali follow..  8  1..........................................................................................................................................................................................MYTIQYIAIIVILTLMIYAFFRHKKGKLELSDLITWEAFFIVLLIIALAPLRISIEI--------------KRIFGLGRGLDALFVLTIGLTYILLFKLYLDIDKIEREITELNRKISIRLKELEDEIERKP....... 118
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Friedberg I, Godzik A. Fragnostic: walking through protein structure space. Nucleic Acids Res. 2005 Jul 1;33(Web Server issue):W249-51.