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Query: [S] KOG4683 Uncharacterized conserved protein, from COG1018

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MAEIKVERSHDQHLLEPKEDTSSSYTRRSLAGNRPRLASLDIFRGLTVALMILVDDAGGDWPMIAHAPWNGCNLADFVMPFFLFIVGVSIALSLKRISNKFEACKKVGFRTCKLLFWGLLLQGGFSHAPDELTYGVDVTMMRFCGILQRIALSYLVVALVEIFTKDSHEENLSTGRIVAASVLVIYLATLYGTYVPDWEFVVYDKDSVLYGKILSVSCGVRGKLNPPCNAVGYVDRQVLGINHMYHHPAWRRSKACTDDSPYEGAIRQDAPSWCRAPFEPEGILSSISAILSTIIGVHFGHIILHLKGHSARLKHWISTGLVLLALGLTLHFTHLMPLNKQLYSFSYICVTSGAAALVFSSLYSLVDILEWKHMFLPLKWIGMNAMLVYVMGAEGILAAFFNGWYYRHPHNTLHVFIRVWHSRRVGVLMYVIFAEILFWGLVTGVFHRFKIYWKLLast
1 -148.000[S] KOG4683 Uncharacterized conserved protein  ali  100  1MAEIKVERSHDQHLLEPKEDTSSSYTRRSLAGNRPRLASLDIFRGLTVALMILVDDAGGDWPMIAHAPWNGCNLADFVMPFFLFIVGVSIALSLKRISNKFEACKKVGFRTCKLLFWGLLLQGGFSHAPDELTYGVDVTMMRFCGILQRIALSYLVVALVEIFTKDSHEENLSTGRIVAASVLVIYLATLYGTYVPDWEFVVYDKDSVLYGKILSVSCGVRGKLNPPCNAVGYVDRQVLGINHMYHHPAWRRSKACTDDSPYEGAIRQDAPSWCRAPFEPEGILSSISAILSTIIGVHFGHIILHLKGHSARLKHWISTGLVLLALGLTLHFTHLMPLNKQLYSFSYICVTSGAAALVFSSLYSLVDILEWKHMFLPLKWIGMNAMLVYVMGAEGILAAFFNGWYYRHPHNTLHVFIRVWHSRRVGVLMYVIFAEILFWGLVTGVFHRFKIYWKL 455
2 -105.000[S] COG4299 Uncharacterized conserved protein  ali follow..  24  1.............................MSQPAARFLSLDVFRGLTVFLMIVVNTAGPGYSQLVHAPWFGFTAADAVFPSFLFAVGCSMAFAFSKPIPLNDFTVKVLRRAALIFLLGFLMYWFPFVRVDGDWALIPFSDTRVMGVLQRIALCYLLAAFAVRWLSPRLIVALCAVLLLGYWAILMAF------------------------------GDPAAPLSKLGNAGTRLDLLLIGQNHLYRKDG---------------------------GFDPEGLLGTLPSTVNVLAGYLAARFLKENPGSSQAMGRMAIAGLVLILA--GLVWSPLFPIAKKLWTSSFVLLTVGIDLILLAGLAKLLEGKASNPGTYFFQVFGLNPLVLYLFSELFVVVLGMIEVAPGVGEWVGVNLFQAVMPGAFGSLLCALAYTLVCW-LLGYVMARRGVVVKL 372
3 -51.100[S] COG3503 Predicted membrane protein  ali follow..  13  2...........................PNSISNSSRLHSIDALRGLVMLFMLLDHGDPMDVASTEPALFLSRTLAHLCAPVFVFLTGLSAFLYGEKHQGRR----AVSAFLFKRGLFLVALELTLVNF---AWTFQLPPTVIYLQVIWAIGLSMLALAALLWLPRPLLAALGVLLVAGHNLLDPLH------------------------------------------------------------------FAPGSAWHLPWAVLHDRGWIEAGDALRLRTSYPLLPWIGVIALGYAAGNWFSGATPATTRRRYLLAGGGGLLLGFILLTLMGFFNVTKYPPSLLFLALTLGIGLLLLAWFERL----DWSGRGKALVAFGGAPMFFYLLHLYLLKLLYLLALAIWGANRGDYFGFS------------SVPALWLCSILLAVALY--HWFAGF 371
4 -22.600[S] COG4645 Uncharacterized protein conserved in bacteria  ali follow..  11  1.............MLQKTFEGGNDQRGVAHPVPTGRDTRLDVFRALCLLTIFVNHVPGQYLEYLTHKNFGFSDSAEA----FVLISGLSVGAAYSGKFLAG-GRLALTLKIWRRALALYVAHIMT------------------------SVVTLAIFAGGALYFGRQELIGEINIRPIVEQTEQGIVAMVLLGHQLGYN-----------------------------NILSMYAVLFLLLPGFLWLNAVRPRLLFAFSATLWLAAGCFKMVPYNFLDDGYWFLNPWSWQFLFVIGILCMSHVRRGGSLPRSPWLLGISVAYLAISAFWVLFSWW--FDKT--FLSLTRLLHVLALAYILATVPVFSRLTRVGSNHPLVMIGRHSLAVFIFGTILAMAGQV--------------LLLVTDRDRIIGTIFVIGGIGLHFAYAYYLEWLKEV.... 376
5 -21.000[S] COG5062 Uncharacterized membrane protein  ali follow..  13  99...............VLRRKPGCCLTKKNENTFDRRIAGVTFYRSVTVTCILAVDFT-----RYAKVETWGTSLMDLGVGSFMFSSGTV------AGRKNDIKKPNAFKNVLWNSFILLILGFARMFLTKSINYQEHVSEYGM-NFFFTLGFMALGVFFFRRSLKKVSYFNLATFITLLHHCLLVLTPF--------------------------------QKWALSAPRTNILAQ------------------------------------------NREGIASLPGYIAIYFYGMYTGSVVLADRPLMYTRAERLLFPLCILLVLYLVSNFLSVGVSRRLANTPYVANVAFINMFFLTIYILI-SVPYGSRVPKLLEDANNNGLLVFLIANVL--------------TGVVNLSFDTLHSSNAKGLTIMTMYLFII-CYMAHWLAQHGIRFRL 459
6 -20.700[S] COG2311 Predicted membrane protein  ali follow..  11  2..................................ERNVTLDFVRGVAILGILLLNFGLPKAAYLNPAWYGAITPRDAWLTLFALLFGAGLQMLLPRGRR----------WIQSRLTLLVLLGFI--------------GLLFWDG----ILLAYGLVGLICWRLVRDAPSVKSLFNTGVMLYLVGLGVLLLLGLISDSQTSRAWTPDASAILYEKYWKLHGGVEAISNRADGVGNSLLALG-----------------------------------------AQYGWQLAGMMLIGAALMRWLKGQFSLRHYRRTGFVLVAIGVTINLPAIALQWQLDWAYRWCAFLLQMPRELSAPFQAIGYGFWPQLSRFKLVLAIACVGRMALTNYLLQTLICTTLFY-----------LFMHFDRLELLAFVIPVWLANILFSVIWLRYFWLWRQLTLRAA 376
7 -20.000[G] COG3594 Fucose 4-O-acetylase and related acetyltransferases  ali follow..  12  2...............LDNIRAGAKGRGSCPAGTNNRDLSFDFAKGILITLVI-----------IGHL-----PYFKSIYPLFMAISGY-----LSSGAILRKSFTQGVGERAMQLLLPMLFWCTLIWTLKSAVIFPMKSLTDTL-STEVIGTYWFIWAAFISFILIRVLTTFNRLSIWIISASAIAVAFAPITLSI--------------------------------------------------------------------------------------TPLLKYTYPFYCLGFLFAQPIGWQNGVIWRYKWIFVVLLSIAAFICFLGWGKETYAYNNLVLLMFSGSLAASAVAMQSMFQCWRLVYSTRVARFVAVQLGQSTLLLYLVQGAVFRLMDLIQFGEVWNLTTRITF-----------ATVLGVAIVVIAMAIRSIARNLGYVSRI 355
8 -18.200[S] KOG0411 Uncharacterized membrane protein  ali follow..  10  87...............GNPSSYPKQSVDAPQDDEPYTSMAIDRTRFCVVIAIFASDFP---NAKLGKSMGYGLKLMDIGVGSFVYNAGFF-------------STRADPQRKMKNALSSFFFGMLRYLSKELLKLDVDDREF---GVHLNFFLMLGVLNLASLVINTRANFLLGFGMCLTHELFLKFFGL--------------------------------EKLIYSSARSSIITS------------------------------------------NIEGITFLLPQMGMFLMAADISKVVFKKKNLSIIILYNAFFVAVLSIARVYS------TSCRRIHNLYFCMVIMLLHTTHGIV-FEVFSRTFKIRNLEMHRFISKYLLFILVWSNML--------------VTLNKLLSASKDMSRCSSHALCITYLVLV-FYVPCAINSKVAKLQV 420
9 -16.400[S] COG4763 Predicted membrane protein  ali follow..  13  2.................................KQKELWINQIKGLCICLVV-----------IYHS-----YFNLYLMPVFFFISGYLIRRYIDSVPWGNCLDKRIWNIFWVLALWGVVQWLALSALNQWLAPERDLSNASLHGMITASTSLWYLYALIVYFVVCKIFSRLALPLFALFVLLSVAVNFVPT--------------------------------------------------------------------------------------PWWGMNSVIRNLPYYSLGAWFGATIMTCVKEVPLRRHLLMASLLAALAVG-------------AWLFTISLLLSLVSIVVIMKLFYQYEQRFGMRSTSLLNVIGSNTIAIYTTHRILVEIFSLTLLAQMNAARWSPQVELTLLLVYPFVSLFICTVAGLLVRKLSQRAFSDLLF... 344
10 -15.400[S] COG3274 Uncharacterized protein conserved in bacteria  ali follow..  10  2.................................TNKIDWIDNLRAVACIMVVMIHSTTYYVTRGAQVGELNWDIANVLVPLFFMISGYLF-------FGEKSAQKKHFMRIGLCLLFYSVIALIYISTLTPIDGWASLRNILQKPVFYAIIVVYLVSPLIKVKPVSGRYLAILILLLAVVANPQTSKFSLDDFRLLPANLY------------------------------------------------------------------------------------IYGDTFYYLLYALLGRAMGMLETQGRMISWGAALLFVVSVICIAISTEKQTRINGSFADTFYMYCSPLVFIAAVSLWVWFKNCL--NQHIAWLSGLARHSLAIYGFHALII--------------HFIRTHHYDFTAYPVLDILYVFALTLGLSTLLSMGLQRIDRRRWV 329
11 -12.700[G] COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis/biofilm formation  ali follow..  12  46...................................SKKSTDCIKGLSILVII-----------LHHIS--GHLAVSM----FLFFSGYGLMVSKLK---KKNYFKGFFSKRLSKVYLPFVIINAITIILTSLIFGTKFNLKDII-FVIAILVFYLCFYVCFKFLSTNLAQHILLFLTFVYFFAMIFMGFREW---------------------------------------------------------------------------------------------WYNTAFCFPLGVYAAINYDALTKFLEKHYVKTLIIALIAFTFF---------FFLAHMLPSAIMPLYQTIASIIFVYLVLLFLFKFRLSSKPLLFLGNIAYEIYLVHMKILVAFFSF-----------------------ARGSYIVYLYLILVIIVAFCFNKKNKKVKL 355
12 -10.600[S] COG4292 Predicted membrane protein  ali follow..  7  43.MSRESLYISACHPYEGSMAENHTHWLRKENTDQTKASFPELF--FDLVFVFALIQLSESLS--DDFSLGIAAEAVLFI-FALWWVWIHTTW-VMDLLDTEIEPVRLLLFTLMFFGIVMAIAL------------------AFKGMGLLFAVAYSAMQVSRSLFALYAFRRGDPASFMTFFRITAWLTI---------------------------------------SSTFWITGGLSEPHLRVVLWIVALVVEYTGPTVRYWVPLIGASPRETLDIDGEHLAERSALFVIIALGILTIGKHTFSNLETEGTPWVLCFSFLTTVLMWWIYFHDG--TAQYLFTYGHLPIVGGIIFTAVGEDFSLAHPYQLGTYNFALAQLG--GPILFLAGTMWMKRVSSRVLPYSHVFGISLLTASFTLVPFVANFAIQALTGVILLVVAVWEYVALK..... 444
13 -10.000[D] KOG3004 Meiotic chromosome segregation protein  ali follow..  14  16.DSVQKDPTVPNGLDGSVVDPTIADPTAITARKRRPQVKLTA-KGLPYVLRIRISSKKNSYDNLSYQLW-----AHELFPKAKFKDFMKICQTVGKTDPVLREYRVSLFR......................................................................................................................................................................................................................................................................................................................................................... 134
14 -9.690[R] KOG3700 Predicted acyltransferase  ali follow..  8  259..........................GDIQNEAEGQVTSLNCIRTISTVWVILGHCAAMLILICTNPV-NAYFAVDT----FFFISAFLLSFLWFKQLQKQRKALIYVHRIARLSPAYYIAILFVTFVYIRMLRDMPAFMS-WLNLLY-YVISWYLATDLQLYLMSPILLLSFAIGGAVFGLFASVVALVASTAFNAYQIFFWYFPPTDYPLGPKDPRYNENERR----------------VWNYYNPLIR--------------------------------------CQIYIMGLVLGYFMRKVPKININPWVDRIMWVLSLGSMVFVVLVIYRSYSKTALAKLESVSEQVFKIIIQNKKNIFINYKYFSLFFFFWTPLARLSFCAYLVHWMVLGYFFGRNHSELYFSTLSYFFLDTVIPVTALSFVIAIFWSSMF------FAKIEGLLLG. 734
FFAS is supported by the NIH grant R01-GM087218-01
1 4 8 3 1 6   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Dunbrack RL Jr, Dunker K, Godzik A. Protein structure prediction in biology and medicine. Pac Symp Biocomput. 2000;(12):93-4.