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Query: [A] KOG4746 Small nuclear RNA activating complex (SNAPc), subunit SNAP43, from COG1018

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MPKGGASCLTPVYAGIRDDLNSFLRAYLQFESVRFFDYKVMFENRGMVGLFTGRHNSAEIIEFNECLLVHCLPYMEECVCPGTPRSLKERLFGLYSLYTFYYIQQEKHVVKVRMDPDSSRNFRRFAQFLLTEKIYDAYALCQKLLEDKAIKQVAFISIHDPSHFKRFYTDDKVSGVSIRTNLNDPLVNVKALVEQFDALGVIHKEYSRLKMKLGITSWMKLKDPIEELKKIIKTSLQAVESSSGVDEIVHTDHSAQQLASRGMQRSSIKDQAHSAALKFSRTRRHRSVKPVIVPAETFEYAPDPKKKKEAQETMPVSGRNGRKRGRPKSVPKSKVSNPARILYEKLAEDMISEHLSTDLTEQEAFTDRPQSSLEPQKNELFNWDAAPQDAQISNQTTEPSCGEDIFIEDFGEFKSQDDVMFTAEDFNDSLIPPLADSDSDLEIDALast
1 -95.400[A] KOG4746 Small nuclear RNA activating complex (SNAPc), subunit SNAP43  ali  100  1MPKGGASCLTPVYAGIRDDLNSFLRAYLQFESVRFFDYKVMFENRGMVGLFTGRHNSAEIIEFNECLLVHCLPYMEECVCPGTPRSLKERLFGLYSLYTFYYIQQEKHVVKVRMDPDSSRNFRRFAQFLLTEKIYDAYALCQKLLEDKAIKQVAFISIHDPSHFKRFYTDDKVSGVSIRTNLNDPLVNVKALVEQFDALGVIHKEYSRLKMKLGITSWMKLKDPIEELKKIIKTSLQAVESSSGVDEIVHTDHSAQQLASRGMQRSSIKDQAHSAALKFSRTRRHRSVKPVIVPAETFEYAPDPKKKKEAQETMPVSGRNGRKRGRPKSVPKSKVSNPARILYEKLAEDMISEHLSTDLTEQEAFTDRPQSSLEPQKNELFNWDAAPQDAQISNQTTEPSCGEDIFIEDFGEFKSQDDVMFTAEDFNDSLIPPLADSDSDLEIDA 445
2 -13.400[S] KOG4610 Uncharacterized conserved protein  ali follow..  10  168LPKGDLT---------RDQLSQLL------------------------LVYIG--TAADIIEFFDSY---------KDDSIAKIGFLVFLTLGIWSWFTIVLSATRGRRPRGSGSHHKEEHTDCCQNCCCGIDVWGIVLNV--ILQDAPFLTFRL---------------------------------------------LIIFQYKIINYMNVFFTCKNSLVIILQLYRLYVVNAEFWKNRRESRMAKSRQFQSRRKVQDADQNSIYMISNERGGDVKKKIKRAKDKDYAEQEAVYSKKKKDKKDKKKRKRKDTGYSTASSQNLYSTKASGTDKDTRRKDKKGKKSKRTCSSSPSDCDLAKKQKRKNADKNDKKKSRKIEAVVEESSSSSSSSSDSSNSTLPSYEVIDEKKARRRKHRGSSSDTSSGDSSSSSSSSSSSDS... 522
3 -11.700[R] KOG2350 Zn-finger protein joined to JAZF1 (predicted suppressor)  ali follow..  7  561....................IQMIDEFSDVNEGE-KELMKLWNL------HVMRHGFVGDCQLPIACEMFLDAKGTEIVRKNLYRNFILHMCSLF------------------IAAETVYKTVQKLQGLLSKY--------------------------AGQELMQRQREEQLKYWLDVGMHKKQEDPKTLKSPQKPAPPADQASTSSASTSGSGSGSSSMQPPKRMPAHLKRGSAASSPGVQSKGTENGTNGSNSSSSNSKNVAKKSADQPLSTLANTRERRSEYGQKRNVSGSRLAATPASKRKLSSKDVEQAADAPEVLTHSDNAVDVGIIDDECGGFGAVGVMNGVASPVANNSEMDTEAEVEAEPTATKAITIHCQQPVTTPVAAAATANERLPGVAPHRRGPRRADRREEELVASAPGYRCRPSMRGADAGAAAAAAAA 939
4 -11.700[R] KOG2295 C2H2 Zn-finger protein  ali follow..  7  158.......................LKQFLDTQD-KYTEYKTDFKRQQLNEFFVAHKDEE----------------------------FKNK-------Y-----HPEDSVKRSEEQRGFLQRRTDVFMELLENGTIGSVKV---------------------------------DSSQADALIRVLDTCVIKLEGGTDEDLKVLDEKPKDPVVYERKAEQMQSVKEVEKTINSPKEEMSEADPVSTQRKPVRPVNSDGENWDDDDAENSAPKKELAEDSKDSDSKPEDKQLNKKKTKKRKRNSSDDDSSSSESSSSSDEEKLKEKYDVEDGLRAEQKTEAEKDRQEATKAKQGPQSPKLDEDEGNENTEPKGLDSKINTYEEIDNTLKSPEISSNPIKNTDNGDGSKVEEDGEKPSVGKDKVVETETIDLDKVKDGQPRALHRTSS 516
5 -11.200[A] KOG4849 mRNA cleavage factor I subunit/CPSF subunit  ali follow..  9  449..........................................................................................................................................................................................................EEVMSRNRTVSSSAIARAVSDAAAGEYSSAIETLVTAISLIKQSKVAHDERCKILISSLQDTLHGIEAKSYNR--RERSRSRERSHRSRQRRERSTSRYRERSRERERDRDRERERDGGRSVRPRKSPEPVVAEAAEAPSSKRYYEDRERYRSSDRERRDRDRDRDRERERDRDRHFTNDGRGLPLDPSNFTSQNPGNIKTGRPKSAAVAGGSMEKPRGQSAWDIIDTDAHWIIKQQTTSIPA 689
6 -9.520[K] KOG2478 Putative RNA polymerase II regulator  ali follow..  9  333...................................................................................................................................................................................................................................................SKRRAKAGVQSGTNALLVVKHRDMNEKELEAQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSGSESEREEGDRDEASDKSGSGEDESSEDEARAARDKEEIFGSDADSEDDADSDDEDRGQAQGGSDNDSDSGSNGGGQRSRSHSRSASPFPSGSEHSAQEDGSEAAASDSSEADSDSD... 531
7 -9.250[Z] KOG3756 Pinin (desmosome-associated protein)  ali follow..  6  379...............................................................................................................................................................................................................................................QDSQPEEVMDVLEMVENVKHVIADQEVMETNRVESVEPSENEASKELEPEMEFEIEPDKECKTLSPGKENVSALDMEKESEEKEEKESEPQPEPVAQPQPQSQPQLQLQSQSQPVLQSQPPSQPEDLSLAVLQPTPQVTQEQGHLLPERKDFPVESVKLTEVPVEPVLTVHPESKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSS 584
8 -8.850[A] KOG2242 Scaffold/matrix specific factor hnRNP-U/SAF-A, contains SPRY domain  ali follow..  6  7...................................................................................................................................................................................................................................................................KVNELREELQRRGLDTRGLKTELAERLQAALEAEEPDDERELDADDEPGRPGHINEEVETEGGSELEGTAQPPPPGLQPHAEPGGYSGPDGHYAMDNITRQNQFYDTQVIKQENESGYERRPLEMEQQQAYRPEMKTEMKQGAPTSFLPPEASQLKPDRQQFQSRKRPYEENRGRGYFEHREDRRG 192
9 -8.580[A] KOG4676 Splicing factor, arginine/serine-rich  ali follow..  8  267...............................................................................................................................................................................................................................................RRSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEKDRERKSESDKDVKQVTRDYDEEEQGYDSEKEKKEEKKPIETGSPKTKECSVEKGTGDSLRESKVNG 472
10 -8.220[S] KOG4418 Predicted membrane protein  ali follow..  6  129.....................................LNCTGNNHRNLQEYRVRKREQDMLKYLAAMLALTITGLMAWTVGSWGDTALWRT-LLFLLYAVYKARNSDWLERWQFTVAVCLEAV-IRYSIRNSGRADTLFIVSQLTVSVNIVIIVAPKFYLSNGEPSRRSMTLGGHSGRAHP------------------SLAKLRDNILNGTIDFAEVPIADMNPEDIRAELKRVYTQLRMYKLKNLYQDNPHISKKRGGKKWSDKNTKATRRISIPSCSPQTKRIEEDEKSDLTVESSPHNIYLSNFKGVNVNSIEQHNSVR.......................................................................................................................... 432
FFAS is supported by the NIH grant R01-GM087218-01
1 4 7 2 5 8   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Pawlowski K, Pio F, Chu Z, Reed JC, Godzik A. PAAD - a new protein domain associated with apoptosis, cancer and autoimmune diseases. Trends Biochem Sci. 2001 Feb;26(2):85-7.