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Query: [E] COG0010 Arginase/agmatinase/formimionoglutamate hydrolase, arginase family, from COG1018

Results of FFAS03 search in CSGID
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MYNTLNNKEDISLVSNNFGFLRLPVHFNPVETDAEWVITGVPFDASVSGRAGTRFGAEAIRRASVNLAWEHCRFPWDFDVRERLKIVDCGDLVYSFGDNQNFVEELEAHATALLKAGKRCLTFGGDHFITLPLLRAHAKHFGKLAMIHFDAHTDTYENGSRYDHGTMFYHAPNEGLIDAAHSVQIGIRTEFDRNLPFTVLSAPQVNEESVAQTVAKIKEVIGDLPVYLTFDIDCLDPAYAPGTGTPVCGGLSTDRALKILRALKDVNIVGMDLVEVSPAYDQSDITALAGATLALEMLYMQGAKKGLast
1 -7.350IDP01387 protease DO VC0566 [Vibrio cholerae O1 biovar El Tor str. N16961]  ali follow..  14  140..........................................................................................DVALLKLNKAKNLTEIRIADSDKLRVGDFAVAIGNGQTVTSGIVSALGRSGLNIEFIQTDAAINSGNSG---------------GALVNLNGELIGINTAILGPNGGNVGIGFAIPSNMMKNLTDQILEFGEVKRGMLGVQGGEITSELADALGYESSKGAFVSQVVP--SAADKAGIKAGDIINGKKIDTFSELRAKVATLGAGKTITLGVLRDG 350
2 -7.290IDP00557 gene: gsrA; serine endoprotease YPO3382 [Yersinia pestis CO92]  ali follow..  12  166..........................................................................................DIALLQLKDAKNLTAIKIANSDQLRVGDYTVAIGNGETVTSGIVSALGRSGLNVEFIQTDAAINRGNSG---------------GALINLNGELIGINTAILAPDGGNIGIGFAIPSNMVKNLTSQMVEFGQVKRGELGIMGTELNSELAKAMKVDAQKGAFISQVVP--SAAAKAGIKAGDIINGKAINSFAGFRAEIGTLPVGSKMTLGLLRDG 376
3 -7.190IDP02087 gene: degQ; serine endoprotease [Salmonella typhimurium LT2] STM3348 [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]  ali follow..  11  139..........................................................................................DIALLQIQNPSKLTQIAIADSDKLRVGDFAVAVGNGQTATSGIISALGRSGLNLEFIQTDASINRGNSG---------------GALLNLNGELIGINTAILAPGGGSIGIGFAIPSNMAQTLAQQLIQFGEIKRGLLGIKGTEMTADIAKAFKLNVQRGAFVSEVLP--SGSAKAGVKSGDVINGKQLNSFAELRSRIATTEPGTKVKLGLLRDG 349
4 -7.180IDP01889 gene: htrA; serine endoprotease [Salmonella typhimurium LT2] STM0209 [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]  ali follow..  13  162..........................................................................................DIALIQIQNPKNLTAIKLADSDALRVGDYTVAIGNGETVTSGIVSALGRSGLNVEFIQTDAAINRGNSG---------------GALVNLNGELIGINTAILAPDGGNIGIGFAIPSNMVKNLTSQMVEYGQVKRGELGIMGTELNSELAKAMKVDAQRGAFVSQVMP--SSAAKAGIKAGDVINGKPISSFAALRAQVGTMPVGSKISLGLLREG 372
5 -7.030IDP90976 gene: degQ; protease [Yersinia pestis KIM 10] y0137 [Yersinia pestis KIM10+]  ali follow..  13  147..........................................................................................DIALLQLTDAKNLTAIKIADSDNLRVGDFAVAVGNGQTATSGIISALGRSGLNLEFIQTDASINRGNSG---------------GALVNLDGELIGINTAILAPGGGNIGIGFAIPSNMAQNLSQQLIEFGEVKRGLLGIRGSEMTADIAKAFNIDAQRGAFVSEVLP--SAAAKAGIKPGDVLDGKKISSFAELRAKVGTTGPGKTIKIGLLREG 357
6 -6.290IDP00190 putative lipoprotein YPO0927 [Yersinia pestis CO92]  ali follow..  13  36............................................................................................................................................................................QAATLNDADVKALSEKSCVEMDQKAQIASADSQYGKRMAKIAAALGDNINGTPAYKVYVTKDVNAWAMANGCIRVYSGL-----MDMMTDNEVEGVVGHEMGHVALGHTRKAMQVAYGTTALRTAIASAGGVVG 165
7 -6.190IDP06281 bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus pneumoniae TIGR4] NP_345317 [Streptococcus pneumoniae TIGR4]  ali follow..  13  87.............................QDPAWHGILVQLPL-------------PKHI-DEEAVLLAIDPEKDVDGFHPLNMGRLWSGHPVMIPSTPAGIMEMFHEYGIDL--EGKNAVVIGRSNIVGKPMAQLLLAKNATVTL----THSRTHNLSKVAAKADILVVAIGRAKFVTADFVKPGA-------------------------VIDVGMNRDENGKLC---DVDYEAVAPLASHITPVPGGVGPMTITMLMEQT........................................... 274
8 -6.090IDP02528 gene: folD; methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase [Bacillus anthracis str. `Ames Ancestor`] GBAA4405 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  11  87.............................GDDRINGILVQLPL-------------PKHI-EEKAIIERISPEKDVDGFHPISVGRMMTGQDTFLPCTPHGIVELVKETNLDI--SGKHVVVIGRSNIVGKPVGQLFLNENATVTY----CHSKTQNMKELTKLADILIVAVGRPKMVTADYIKEGA-------------------------VIDVGVNRLETGKLC---DVDFDNVLDVASYITPVPKGVGPMTITMLLHNT........................................... 274
9 -6.060IDP02022 gene: folP; dihydropteroate synthase [Coxiella burnetii RSA 493] CBU_1351 [Coxiella burnetii RSA 493]  ali follow..  12  30.....................................VMGIINVSPNSFYHPHLDLNSALRTAEKMVD-------------EGADILDIGG----------------EATNPFVDIKTDSPSTQIELDRLLPVIDAIKKRFPRVMREAVNTGADMINDQRALQLDDALTTVSALK-------TPVCLMHFPSETRKPGSTTHFYFLQSVKKELQESIQRCKKAGISEDRIIID-------PGFGQGN--GKNVSENFYLLNKLPEFVAMGLPVL................................ 232
10 -5.990IDP01638 gene: folD; folD bifunctional protein [Coxiella burnetii RSA 493] CBU_0312 [Coxiella burnetii RSA 493]  ali follow..  13  88.............................RDSNTHGILLQLPL-------------PAHI-DPANLLERIRPDKDVDGFHPYNLGRLVQRRPALRPCTPYGVMTLLTETHENL--EGKHAVIVGASNIVGRPMALELLLAKCTVTV----CHRFTRDLAEHVKSAELLIVAIGKPGIIQSEWIKPGA-------------------------VIDVGFSRLSPNKIA---DIDFETAKERASWITPVPGGVGPMTVATLLENT........................................... 275
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Lesley SA, Kuhn P, Godzik A., Deacon AM, Mathews I, Kreusch A, Spraggon G, Klock HE, McMullan D, Shin T, Vincent J, Robb A, Brinen LS, Miller MD, McPhillips TM, Miller MA, Scheibe D, Canaves JM, Guda C, Jaroszewski L, Selby TL, Elsliger MA, Wooley J, Taylor SS, Hodgson KO, Wilson IA, Schultz PG, Stevens RC. Structural genomics of the Thermotoga maritima proteome implemented in a high-throughput structure determination pipeline. Proc Natl Acad Sci U S A. 2002 Sep 3;99(18):11664-9. Epub 2002 Aug 22.