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Query: [J] COG0013 Alanyl-tRNA synthetase, from COG1018

Results of FFAS03 search in CSGID
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MKTMTSAEVRQMFLDFFKSKGHTVEPSQSLVPVNDPTLLWINSGVATLKKYFDGSVVPENPRLTNAQKAIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRKEAIAFAWELLTSSEWFEFPAEKLYITYYPADKDTYNRWVEVGVDPTHLVPIEDNFWEIGAGPSGPDTEIFFDRGEVYDPEHVGLKLLAEDIENDRYIEIWNIVLSQFNADPSIPRSEYPELPQKNIDTGMGLERMVCIIQGGKTNFDTDLFLPIIREIEKLSGKTYSPDSENMSFKVIADHIRSLSFAIGDGALPGNEGRGYVLRRLLRRAVMHGKKLGIQGKFLASLVPTVGKIMQSYYPEVLEKEDFIMQIIDREEETFNRTIDAGQKLIDELLLNLKSEGKDRLEGADIFRLYDTYGFPVELTEELAEDEGFKIDHEGFKVAMKAQQERARAAVVKGGSMGAQNETLSSIEVESEFLYEDKTTQGKLLVSIQDDEIVDEVSGKAQLVFDVTPFYAEMGGQVADHGVIKDAEGQVVANVLDVQHAPHGQNLHSVETLSPLKVGESYTLEIDKERRAAVVKNHTATHLLHAALHNIVGNHALQAGSLNEVEFLRFDFTHFAQVTKEELAEIERQVNEVIWQSLKVETVETDIATAKEMGAMALFGEKYGKNVRVVKIGDYSIELCGGTHTQTTSEIGLFKIVKEEGIGSGVRRIIAVTGQKAYEAFKDAENTLNEVATMVKAPQTSQVLAKVTSLQDELKTAQKENDALAGKLAASQSDEIFKNVQTAGSLNFIASEVTVPDANGLRNLADIWKQKELSDVLVLVAKIGEKVSLLVASKSSDVKAGNLVKELAPFVDGRGGGKPDMAMAGGSKAAGIPELLAAVAEKLALast
1 -215.000IDP05327 gene: alaS; alanyl-tRNA synthetase [Listeria monocytogenes EGD-e] lmo1504 [Listeria monocytogenes EGD-e]  ali follow..  52  1MKQLSSAEVRQLFLDFFKEKGHTIEPSAPLVPNNDPTILWINSGVATMKKYFDGSVIPDNPRMANAQKSIRTNDIENVGKTARHHTFFEMLGNFSIGDYFKEGAIVFAWEFLTSPKWIGFDPDKLYVTVYPEDEEAKTLWREIGLSDDHIVEIEDNFWDIGIGPSGPDSEIFYDRGPAFGDDA-SDPELYPGGENERYLEIWNLVFSQFNHNP---DGTYTPLPKQNIDTGMGLERMVSIIQDAPTNFETDLFMPIIREVEQIAGVKYGSQENDVAFKVIADHIRTVAFAIGDGALPSNEGRGYILRRLLRRAVRYAKVLTINEPFMYKLVPVVGKIMNSFYPEVENQTDFIQKVIRTEEERFHETLNEGLAILETILKTAKETNEQVIKGADIFKLYDTFGFPVELTEEYAEDHGLKVDHAGFEAEMKEQRARARAARADVKSMQVQELLANLTEKSAFVGYNSTEHVSEILYLIQNDTLVDEAGNEAQVIFKETPFYAESGGQVADKGTIESETGLAYV-EDVQKAPNKQNLHRISVKEGVLKTGDTVKLAVDKVKRRETIKNHTATHLLHRALKDTLGEHVNQAGSLVSPDRLRFDFSHFGQITEEELTKMEEIVNEKIWEQINVVIEEMPIAEAKELGAMALFGEKYGDIVRVVQVGKYSIELCGGVHVRNTADIGLFKIVSETGIGAGTRRIEAVTGKEAYRFVTEQENTLKQAASLLKTT-TKETPQKVELLQADLREVKRENESLLSKLASAASADIFESPEEIGGVKVIAKQVNAKDMNQLRQFVDNWKDKKIGGILVLGAVQGDKVNLISAVSEEGYHAGKLLKEVATRCGGNGGGRPDMAQAGGKNPAELGTALDYVSTWVK 875
2 -214.000IDP05710 gene: alaS; alanyl-tRNA synthetase [Staphylococcus aureus subsp. aureus COL] SACOL1673 [Staphylococcus aureus subsp. aureus COL]  ali follow..  48  1MKKLKASEIRQKYLDFFVEKGHMVEPSAPLVPIDDDTLLWINSGVATLKKYFDGRETPKKPRIVNSQKAIRTNDIENVGFTARHHTFFEMLGNFSIGDYFKQEAIEFAWEFLTSDKWMGMEPDKLYVTIHPEDMEAYNIWHKIGLEESRIIRIEGNFWDIGEGPSGPNTEIFYDRGEAYGQDD-PAEEMYPGGENERYLEVWNLVFSEFNHNK---DHSYTPLPNKNIDTGMGLERMASVSQNVRTNYETDLFMPIMNEIEKVSGKQYLNNEQDVAFKVIADHIRTIAFAISDGALPANEGRGYVLRRLLRRAVRFSQTLGINEPFMYKLVDIVADIMEPYYPNVKEKADFIKRVIKSEEERFHETLEDGLAILNELIKKAK-ATTNEINGKDAFKLYDTYGFPIELTEEIAVQAGLKVDMTTFESEMQQQRDRARQARQNSQSMVQSEVLKNITSASTFVGYDTATAQTTLTHLIYNGEEVSQAGETVYFMLTETPFYAISGGQVADTGIVYNDNF--EIAVSEVTKAPNGQNLHGVVQFGQVNVGATVSAEVNQNDRRDIQKNHSATHLLHAALKSVLGDHVNQAGSLVEADRLRFDFSHFGPMTNDEIDQVERLVNEEIWKGIDVNIQEMDIASAKEMGAMALFGEKYGDVVRVVNMAPFSIELCGGIHVRNTSEIGLFKIVSESGTGAGVRRIEALTGKAAFLYLEDIQEKFNTMKSQLKVKSDDQVVDKLTQLQDEEKALLKQLEQRDKEITSLKMGNIEDQVEEINGYKVLVTEVDVPNAKAIRSTMDDFKSKLQDTIIILASNVDDKVSMVATVPKSNVKAGDLIKQMAPIVGGKGGGRPDMAQGGGTQPENISKSLSFIKDYIK 874
3 -209.000IDP04730 alanyl-tRNA synthetase [Bacillus anthracis str. Sterne] BAS4284 [Bacillus anthracis str. Sterne]  ali follow..  52  1MKQLTGAQIRQMFLDFFQEKGHAVEPSASLVPHEDPSLLWINSGVATLKKYFDGRVIPQNPRITNAQKSIRTNDIENVGKTARHHTFFEMLGNFSIGDYFKEEAITWAWEFLTSDKWIGFDKELLSVTIHPEDEEAFTIWNEMGVPKERIIRLEENFWDIGEGPSGPNTEIFYDRGEAYGNDF-SDPELYPGGENERYLEVWNLVFSQFNHNP---DGSYTPLPKKNIDTGMGLERMTSIVQDVPTNFDTDLFMPMIGATETISGEKYGDLEKDMAFKVIADHIRTVTFAVGDGALPSNEGRGYVLRRLLRRAVRYSKKLNINRPFMFELVPVVGEVMKDFYPEVLEKKDFIAKVVKNEEERFHETLHDGEAILSEVIAKAKEEKTTVISGVDAFRLYDTYGFPIELTEEYAEEAGMTVDHEGFENEMEKQRERARAARQDVDSMQVQGVLGEVKVASEFVGYGTVATESNVVALVKNGEYTDSVGEEGQLMLDVTPFYAESGGQIADRGCLLADGV--KVLVKDVQKANGQNLHQVVVEEGTLTKDAAVKAIIDTKNRSSVVKNHTATHLLHQALKDVLGTHVNQAGSLVTSERLRFDFSHFGQVQADELEKIERIVNEKIWESIDVEISQKAIEEAKEMGAMALFGEKYGDVVRVVQVGDYSLELCGGCHVDNTASIGIFKIVAESGIGAGIRRIEAVTGKSAYELMNDQVGLLKEAAGKMKTN-PKDILTRVDGLFAEVKQLQKENESLAAKLSNIEAGNLTDSVMTVDGVNVLAAKVNVADMNNLRTMMDDLKNKLESAVVVLASVNDDKVNILAGVTKDGYHAGKLVKEVASRCGGGGGGRPDMAQAGGKNPAQVEEALAFVQEYVK 876
4 -208.000IDP90826 gene: alaS; alanyl-tRNA synthetase [Yersinia pestis CO92] YPO3305 [Yersinia pestis CO92]  ali follow..  41  2..SKSTAEIRQAFLDFFHSKGHQVVSSSTLVPNNDPTLLFTNAGMNQFKDVFLGLDKRAYSRATTSQRCVRANDLENVGYTARHHTFFEMLGNFSFGDYFKHDAINFAWELLTSEQWFNLPKEKLWVTVYETDDEAYNIWANVGVPHERIIRISDNFWQMGTGPCGPCSEIFFDHGDHIW----GGPPGSAEEDGDRYIEIWNIVFMQFNRQS---DGTMLPLPKPSVDTGMGLERIAAVLQHVNSNYEIDLFRDLIAAVADVTGATD---LSSKSLRVIADHIRSCAFLISDGVIPSNENRGYVLRRIIRRAIRHGNMLGAKETFFYKLVAPLIAVMGPAAAELKQQQAMVEQVLKTEEEQFARTLERGLALLDDELSK---LTGDTLDGETAFRLYDTYGFPVDLTADVCRERNLKVDEAGFEQAMEAQRRRARESSGFGA---DYNSLIRVDSASQFSGYDHVQQHATVTALFRNGEAVDEAGEEAVVVLNRTPFYGESGGQVGDKGELKNATA--TFSVTDTQKYGQAIGHVGILTTGTLRVNHSVEALVDVVRRNRIRLNHSATHLLHAALRNVLGEHVAQKGSLVNDKYLRFDFSHFEAMKPEQIRLVEDLVNEQIRRNMPVQTEVMELDAAKEKGAMALFGEKYDDQVRVLTMGDFSTELCGGTHASRTGDIGLFRILTESGTAAGIRRIEAVTGEGAIALLHQQSDLLQDVAHLVKGD-IHNLADKVRAVLDRSKMLERELQQLKDQQAAQESASLSSSAKLINGVKLLVSQLDNVEPKMLRTMVDDLKNQLGSAIIVLATTADDKVSLIVGVTKDKVKAGELIADIAQQVGGKGGGRPDMAQAGGTDVQALPAALASVEAWVA 872
5 -207.000IDP92131 alanyl-tRNA synthetase, putative [Toxoplasma gondii ME49] TGME49_019540 [Toxoplasma gondii ME49]  ali follow..  32  21AKGWSGEAVRGAYLEFFEAQGHLIYPSSPVIPRGDNTLLFINAGMNQFKPIFLGQIDRSLRRVADTQKCIRANDLEDVGKDVYHHTFFEMLGNWSFGDYFKREAIAWAWQLLT--EVYKIPKDRLYASYFGGDEEARDIWLQ-YLPANRVLPFKENFWEMATGPCGPCSEIHYDRIGGRDASS------LVNADDPSVLEIWNLVFMQYNREK---DGSLTPLPAPCVDTGMGLERVASVLQDKQSNYDTDLFTALFDKILELSPGLRDKDMVDMAYRVLADHARCLTAAIADGAEPSNEGRGYVLRRILRRAVRYARQLGMAEGNFPKLVPVVVSLLGETFPEMKKNEEKVVRILLKEEQQFSRTLDNGVERFKKVANSLQAKGQKVFPGGEAFTLYSTYGFPLDLTQLMAEEVGLQVDAEEFERKFDAHRAASENTSFKQGGAGAEWNVKDQAALMTQDAVEAAPIKAKVMAIWDGKRFAPEGENLVAVILDKTCFYAEQGGQIGDVGRLVDLSSQAEFEVVDSQKSGDFILHIGSMSKGTLREGTELVPAVDYVRRFRLAQHHTGTHLLNFALREVLIRKIQQKGSLVEVKRLRFDYAGEKPLENEDIIAVENVVKDCIAQARPVHYKEVPLEQAMKIGLRAVFGEVYPDPVRVVSVGEASIELCGGTHLHNASQLSDFCILSEESVAKGVRRVVAAAGDAAFEARKELEELEEAFRSLASAPRERSLVKQLEQAQKALLELQKARSKELVKEAKK-LGEELGTEHKTKPFLVLNLPQLLGDGKALDAASQTLHQAAPDLPFLLVTASAATGTAAIAFVPAQLHAASWLTACVGLLGGKGGGKGERAVGAAKEGDKVDAAVAEATAFAE 1032
6 -199.000IDP90679 gene: alaS; alanyl-tRNA synthetase [Campylobacter jejuni subsp. jejuni NCTC 11168] Cj0506 [Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819]  ali follow..  40  2.......DIRKAYLDFFASKGHEITPSSPLVP-DDATLLFTNAGMVPFKSIFTGEIPRPPPRKTSCQTCIRANDLDNVGYTARHHTFFEMLGNFSFGDYFKEQAIAYAWEFVT--EVLKLPKDRLYVTVHENDDEAFNLWQK-HIQKERIYKFKDNFWQMGTGPCGPCSEIFYDQGQEHF----NSSEDYMGGDGDRFLEIWNLVFMQYERSA---DGVLSPLPKPSIDTGMGLERVTAIKEGKFSNFDSSLFMPIINEISKLCNKTY-VYESGASFRVIADHIRSSVFLLAQGVSFDKEGRGYVLRRILRRALRHGYLLGFKQAFMYKLVDVVCDLMGGHYTYLNEKKDFIKEQIRLEEERFLSTIENGIEIFNEELKN----TKEIFSGEVAFKLYDTYGFPLDLTADMLREKNLKVDEEKFELFMNEQKARAKASWKGSGDKTASKNLLEKFGENHFVGYEKAECESKILALLDEDFEVSTLKDAGWVMLENTPFYATSGGQSADSGFIA------KREVLDTQKFFNLNLSFIKA-GEELKVNDIVHARIDTEKREQIARHHSATHLLHHALREILGSHVSQAGSLVESNKLRFDFTHHKALNKEELESIEKRVNKMIINSSEAILENMPLEEAKKSGAIALFNEKYQGNVRVLTLG-ESKELCGGTHVKNTAQIGSFYIVKESGVSAGVRRIEAVVSKAALEFVKNQLEELSKVKDELKNNDILSGIKKLKNEILSLKN------------ELKNSSKTELDSKNIQGVEICVKRI---DNGDIKAMIDDFKNKFAKAVILLIQVKDEKITLAAGVKDVPLKAGALVKEAAQILGGNGGGRDDFATAGGKDLSKINEALKQSLETIE 839
7 -57.800IDP06256 gene: glyQ; glycyl-tRNA synthetase subunit alpha [Streptococcus pneumoniae TIGR4] NP_345929 [Streptococcus pneumoniae TIGR4]  ali follow..  15  3.KKLTFQEIILTLQQFWNDQDCMLMQAYDNEK---------GAGTMSPY-TFLRAIGPEPWNAAYVEPSRRPAD----GRYGENPNRLYQHHQFQVVMPSPSNIQELYLESLEKLGI----------------------------PLEHDIRFVEDNWENPSGSAGLGWEVWLD------------------------MEITQFTYFQQVGG--------LATGPVTAEVTYGLERLASYIQEVDSVYDIEWADGVFDKFEKEAGRALEEGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIAR--IRNLARVVAKTFVAE----------RKRLG--YPLLDEETRAKLLAEDAE................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 305
8 -56.100IDP05557 gene: glyQ; glycyl-tRNA synthetase subunit alpha [Listeria monocytogenes EGD-e] lmo1459 [Listeria monocytogenes EGD-e]  ali follow..  13  1............................................MSPY--TFLKAIGPEPWKAGYVEPSRRPAD----GRYGENPNRLFQHHQFQVVMKPSPDNIQELYLGSLEKLGINPLEHDI--------------------------RFVEDNWENPLGCAGLGWEVWLD------------------------MEITQFTYFQQVGG--------LECFPVTSEITYGVERLASYIQDKENVFDLEWTEGIFDTYEREATRQMQDGLVFPAYDYVLKCSHTFNLLDARGVVSVTERAQYIGRRNLARRIAYESREKLGFPLLKEEGGKRHE........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 263
9 -55.900IDP90793 gene: glyQ; glycyl-tRNA synthetase subunit alpha [Campylobacter jejuni subsp. jejuni NCTC 11168] Cj0704 [Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819]  ali follow..  10  1...MTFSQMILNLQNYWQEQGCAIMQPYDMPAGAGTFHPAT----------FLRSLGKKPWAAAYVAPSRRPTDGENPNRLGAYYQFQVLIK------PSPDNIQELYLKSLEN--------------------------LGFDLKSHDIRFVEDNWESPSLGAWGLGWEVWLD------------------------MEVTQFTYFQQVGG--------IAVDLVSAEITYGLERIAMYLQNVDNVYDIKILNEQFENSYKECKNILEQGLALPAYDYCMLAAHTFNLLDARGAISVAQRQDYMLK--IRELSKNCAEIYKKN.................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 282
10 -51.200IDP90920 gene: glyQ; glycyl-tRNA synthetase subunit alpha [Vibrio cholerae O1 biovar eltor str. N16961] VC0021 [Vibrio cholerae O1 biovar El Tor str. N16961]  ali follow..  12  29YDIKTFQGMILALQDYWAQQGCTIVQPLDMEVGAGTSHPMT----------CLRALGPEPIATAYVQPSRRPTDGRYGENPNR------LQHYYQFQVIIKPSP----------------NIQELYLGSLRV--------LGVDPCVHDIRFVEDNWENPTLGAWGLGWEVWLN------------------------MEVTQFTYFQQVGG--------LECKPVTGEITYGIERLAMYIQGVDSVYDLV-WTDGPLGKVTYGDIFHQNEVELPAYERILKAAHAFNLLDARKAISVTERQRYILR--IRNLTKSVAEAYYAS.................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 315
11 -9.300IDP90668 gene: thrS; threonyl-tRNA synthetase [Campylobacter jejuni subsp. jejuni NCTC 11168] Cj0206 [Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819]  ali follow..  19  20...............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................VKNTNLKEIYFDNSKESLEVIRHSCAHLMAQAIKSLYPEAKFFVGPVIE-DGFYYDFRVESKIGEEDLVKIEKKMKELAEAKIEISKYEITKSEALAK-KQEVLLRIPDRAVSIYKQGEF-EDLCRGPHVPNTKFLRFFKLTRVAGAREMLTRIYGTA........................................................................................................................................................................... 187

FFAS is supported by the NIH grant R01-GM087218-01
1 4 6 8 2 5   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Luz JG, Hassig CA, Pickle C, Godzik A., Meyer BJ, Wilson IA. XOL-1, primary determinant of sexual fate in C. elegans, is a GHMP kinase family member and a structural prototype for a class of developmental regulators. Genes Dev. 2003 Apr 15;17(8):977-90. Epub 2003 Apr 02.