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Query: [M] COG1732 Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein), from COG1018

Results of FFAS03 search in CSGID
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MTISKLWVSSLALLATVSLPLQAASPVTVGSKIDTEGALLGNMILQVLESHGVKTVNKIQLGTTPVVRGAITAGELDIYPEYTGNGAFFFKDENDPAWKNAKQGFEKVKKLDAEQNKLVWLTPAPANNTWTIAIRQDIAEKNKLSSLADLSRYLKEGGTFKLAASAEFIERADALPAFEKAYDFTLNQNQLLSLAGGDTAVTIKAAAQQTSGVNAAMAYGTDGPVAALGLQTLSDPKGVQPIYAPAPVVRESVLQAYPQIADWLQPVFASLDEKTLQQLNARIAVEGLDAKKVAADYLRQKGWVKLast
1 -91.500IDP05685 gene: opuCC; hypothetical protein lmo1426 [Listeria monocytogenes EGD-e] lmo1426 [Listeria monocytogenes EGD-e]  ali follow..  22  1MKKSVLLLTSSLFLSSCSLGGSSKDTIRIGAMATTESQIVSNILKELIEHDGLKVEIVNNLGSTIVQHQAMLNGDVDITATRTGTDLVGPLGEEA--IKDPEKALAAVKKGFEERFHQTWFDSYGFANTYVFMVRQDTAKKYNLNTVSDMRKVENE---LTAGVDNSWMEREDGYKAFSKAYDIEFKKIF-------PMQIGLIYTALKNNQMDVALGYSTDGRIPTYNLKLLKDDKKFFPPYDASALATDEILKKHPELKTTINKLKGKISTEEMQKLNYEADGKLKEPSIVAQEFLQKNNYFE 305
2 -82.700IDP92715 gene: proWX; choline transporter (glycine betaine transport system permease) [Streptococcus pneumoniae D39] YP_817092 [Streptococcus pneumoniae D39]  ali follow..  25  214...ALMALLLGLSYSPALLAQKEKENLIIAGKIGPEPEILANMYKLLIEENSMTATVKPNFGTTSFLYEALKKGDIDIYPEFTGTVTESLLQPSPKVSHEPEQVYQVARDGIAKQDHLAYLKPMSYQNTYAVAVPKKIAQEYGLKTISDLKKVEGQ---LKAGFTLEFNDREDGNKGLQSMYGLNLN--------VATMQPALRYQAIHSGDIQITDAYSTDAELERYDLQVLEDDKQLFPPYQGAPLMKEALLKKHPELERVLNTLAGKITESQMSQLNYQVGVEGKSAKQVAKEFLQEQGLLK 505
3 -16.100IDP05119 ABC transporter, substrate-binding protein [Clostridium difficile 630] CD2989 [Peptoclostridium difficile 630]  ali follow..  11  7LIGITILTLATASLAGCAKKNNGEKEINLTYVKSPLNVPSDDLFGKEFKKDNIKVNFHEITTGPEQT-QALAAGEIDFLHALGGTSALIAASNGVE---------------------LKILNTYSRSPKGFMILTNNN----SIKSAADLV---GKKVAGPKGTILHQV-----LISALDKEGLSMDDVEFVNMGIPEAS-----AALSDGSVDAALIAGP-LKAMKSGSKLVANGEGLVDGIIVT-AVSTDFAEKHPEIVERF-----------MKVEKETLEYVNNNFDEAMEKVAKEVDL.. 266
4 -16.000IDP05270 gene: gbuC; hypothetical protein lmo1016 [Listeria monocytogenes EGD-e] lmo1016 [Listeria monocytogenes EGD-e]  ali follow..  15  5...............................................................................................................................................................................QNAIKDYHLDDDNWQLQTSSTAAMTSTLQ-KAMKDKRPIVVTGWTPHWMFTKFDLKFLDDPKNVYNAENIHTIVRKGLKEDKPSAYQVLDNF--FWTAEDMSEVMLEVN-DGVDPEEAAKKWIKNN.... 127
5 -15.800IDP05042 putative sulfonate ABC transporter, sulfonate-binding protein [Bacillus anthracis str. Ames] BA_2921 [Bacillus anthracis str. Ames]  ali follow..  13  1MYKLSFTLAISLFLFGCEKSTASSKTVQIGIQQGLSPLLLAQWFEEEFKKEGVKVK--TEFQSGPPYFEAIASNRLDF---EVGNSPVISAQAAGIGFT-------------------EIANTSYARKGTGILVQKDS----KITSIKELK-------GKKIAVAKGSSAFNLLYRALDKE-GINAKDVNVIQLQPDEAQP-----AFESGSVDAWAIWDISLHTVNKGAKVITDGERLNVSSPEFLIARTKFAKEHPELVEKF-----------LKVYEKARVWQDENLDEAIKIYTSAKKI.. 266
6 -15.700IDP91135 hypothetical protein SAOUHSC_00137 [Staphylococcus aureus subsp. aureus NCTC 8325] SAOUHSC_00137 [Staphylococcus aureus subsp. aureus NCTC 8325]  ali follow..  9  1MKRLSIIVIIGIFIITGSKNAQNQQVIKIGYLPITHSLMMTKKLLSQYNHPKYKLELVKFNNWPDLM-DALNSGRIDGASTLIELAMKSKQKGSN-----------------------IKAVALGHHEGNVIMGQKGM----HLNEFNNNGD------DYHFGIPHRYSTHYLLLEELRKQLKIKPGHFSYHEMSPAEMP-----AALSEHRITVAEPFGALGEKLGKGKTLKHGDDVIPDAYCCVLVLRGELLDQHKDVAQAF-KQSRDVLTQSAAWTSYGDLTIKPSGYQEITTLVKQHHLFN 305
7 -14.200IDP05622 ABC transporter, substrate-binding lipoprotein [Clostridium difficile 630] CD0999 [Peptoclostridium difficile 630]  ali follow..  10  1MKKILLVVLTMVVLVGCSPGKDNPKQVKVAVPDGLPAVAIAKLANEPEIKEGYETVYSI-EKTPEAISTRVMKKDADIAIVPSNMAAIAYNKTSS----------------------YNIVGTVGMGSLYLVS-------TENIKDYSDLV-------GKEVGCTGKGLTPDITIKSLLLQKDINYSDIKFNYVSSAS-----LVPLLATGKVKTGIVALSALMSKNPDIKIIKSLNDSWKEVSSTLIVKSEFLRDNKDFVDSF-----------VGQLSNSIDWANKNPEELGA.......... 267
8 -13.200IDP01383 thiosulfate ABC transporter, periplasmic thiosulfate-binding protein VC0538 [Vibrio cholerae O1 biovar El Tor str. N16961]  ali follow..  10  1MNRIKSTLTALLLAGSFQASAADQTILNSSYDIAREVAYNPVFAEHWQQKTGKTVEIKQSHAGSSAQARSILQGAADVVTFNQVTDVQILHDKGKLIPANWQTLLPNAS----------------YYSTTAFLVRKGNPK--NIQDWSDLVR-----DDVKSVFPNP-KTSGNARYTYLAALGFALKKFLANVAVFDTGGRGATTSFVERGIGDVLITFESEVNNIRDDYQVVVPKTSILAEFPVAVVEKVAKRNGTYDVATEYEPAQRLLAEFNYRVHDAKVQAEFAEREQAMQTQFANGAKLD 328
9 -11.800IDP01405 gene: metQ; lipoprotein YaeC VC0905 [Vibrio cholerae O1 biovar El Tor str. N16961]  ali follow..  12  1MKFTIAAAASTLILAGCGEKAVDNNKVKIGVMAGAEAQVAEVAAKVAKEKYNLDVELV-TFTDYVTPNAALDDGSIDANAFQHKPYLDKQIADRGYKLAIVGNTFVYPIAGYSKQIK----SVDELQDGARIAVPNDPTNLRSLLLLQQQGLLKLREDVGLLATVRDIVENPKKLE--------------------LELDAAQLPRSLDDVALSIINTYASSINLTPEKDGIFVENKE--SPYVNILVAREANVNA-----ENVQNFKKAYQTDEVAKA.......................... 256
10 -11.500IDP00164 gene: acfC; accessory colonization factor AcfC VC0841 [Vibrio cholerae O1 biovar El Tor str. N16961]  ali follow..  11  1MYFMKSKNRFLLISLLSFSTSVFADVNLYGPGGPHVP--LIKVAESFEKSQSKRVN--ITFGPQATWNDKAKKNA-DILFGASEHSALAIAEGHSERFSKFNIH---------------------FMREAIILVKKG--NPKNIKGMADLLK-----PGIGIVVNDGAGVSNTSGTAVWEDSVGRMKNVEKLQAFRSNIHVSARKAFVDGEDIDAWITWVDWAIANPTIGDMVRMEDEYRIYRDFNVVLAKNPSSEAIDFFDYLTK------------------------SKDAEAIFQHYGWFK 256
11 -11.500IDP05357 putative ABC transporter, substrate-binding protein [Bacillus anthracis str. Ames] BA_0382 [Bacillus anthracis str. Ames]  ali follow..  11  1MKKGLKVMLAALLAVGVAGSASKDQKVKVVLDWFPNTNHTGLYVAQYYKKQGLDVEIIQPGDNVTAE-QMIASGKADFAISAQENVTLARVEGIP----------------------VVSVGAIIQHNTSAFASLKK----DNMTSPKDFE-------GKRYGGWGGPAEEA--LKTIMDKHQADFNKVEKIILGQTDF------FKSIGRDADFEWIYYGWDGIEELNTIMVKDLDPALDFYSPVMITSEKHTKQDKDFVKKFMSATTEGYNFAIKEPKEAADILIKAVPDVNKDLVQES.... 277
12 -11.400IDP91987 ABC transporter substrate-binding protein [Streptococcus pneumoniae str. Canada MDR_19A] SpneCM_010100008765 [Streptococcus pneumoniae str. Canada MDR_19A]  ali follow..  11  1MKKTLVTALVAVVLVACGQGTASKKKVDFILDWTPNTNHTGLYVAKYFKEAGVDVDLKLPPEESSS--DLVINGKAPFAVYFQDYMAKKLEKGAG----------------------ITAVAAIVEHNTSGIISRKS----DNVSSPKDLV-------GKKYGTWNDPTELA--LKTLVESQGGDFEKVEKVPNND-----SNSITPIANGVFDTAWIYYGWDGILDANFMYLKDYVKEFDYYSPVIIANNDYLKDNKEEARKVIQAIKKILIKNAPELKEKRDFVIESQKYLSKKWDKENGILK 321
13 -11.300IDP05207 putative sulfonate ABC transporter,solute-binding lipoprotein [Clostridium difficile 630] CD2365 [Peptoclostridium difficile 630]  ali follow..  11  1MKLILFGVMGTSILTGCSSKPKEKETITVGYYNCDHMTGPVAESAGIYKDLGLNVK----TVGNGKVPEAMAAGKMDAGYIGTKGLVGAIPKGSP----------------------ITIAANNHTGGSEYLIVSKD------IKEPKDLI-------GKKIATDMS-------DYGPETGLPTDPSKYEVVNMDSDK-----KYLALKTGKIQAFTSCDPWGSVAEND-KIIASTQYKEKANGCSFSLNKNFIKEHPDLAKKL-----------VLAHTKAIEYIYTNPAEAAKIFAKYYNV.. 272
14 -11.100IDP05024 ABC transporter, substrate-binding protein, putative [Bacillus anthracis str. Sterne] BAS4675 [Bacillus anthracis str. Sterne]  ali follow..  7  1......MLLAVFTFAACSSKKEGTKNIRIGEVTHSLFYAPLYVGIEFFKDEGLNVDLQTTAGGDKTM-TALLSGGIDIALVGSETSIYVHQQGAKDP--------------------IINFAQLTQTDGTFLVSRKKL----DSFNWNDVK-------GVTFLGQRKGGMPQMVGEYVLKKNGIDPHKDTNL----QNIEFANIANAYASGTGEFVQLFEPTASIFEKE-YIVASFGNESGTVPYTSFMKESFLKKDKAAAE-------KFTRALYKAQQWVDTHSPEEIADAVSPLFKD..... 261
15 -10.900IDP91970 lipoprotein [Streptococcus pneumoniae str. Canada MDR_19A] SpneCM_010100005433 [Streptococcus pneumoniae str. Canada MDR_19A]  ali follow..  11  7LGLVALATVAGLALAACGNKADNATTIKIATVNRSGEEKRWDKIQELVKKDGITLEFT-EFTDYSQPNKATADGEVDLNAFQHYNFLNNWNKEN--------------------GKDLVAIADTYISPIRLYSGLNGSANK--YTKVEDIPA------NGEIAVPNDATNESRALYLLQSAGLIKLDVENPKNLKITELDASQTARSLSSVDAAVVNNFVTEAKLDYKKALFKEQADENSKQWYNIIVAKKD--WETSPKADAIKKVIAAYHTDDVKKV.......................... 271
16 -10.600IDP02622 ABC transporter, periplasmic substrate-binding protein [Coxiella burnetii RSA 493] CBU_0109 [Coxiella burnetii RSA 493]  ali follow..  12  1MLKKLMRLLISGVMLTACHQKEAKNEVRVGTIAGPETQLMEVAKQVALNRYGLHVNII-TFSDYNTPNEALADGSVDANMFQHLPYLKAQIEMRGYKIVSIGKTFVYPMGLYSKKIT----ALTQLKTGAKIAVPSDPSNERALLLLEKAQLIQLKTHVTINATPMDIASNPKKLK--------------------VELDAAQLSRSLGDVDLAAINTYAIPAGLSPSRDALLTEGPN--SPYANVVAVREDDKND-----PRLKQLVSALHSPAVLSA.......................... 253
17 -10.500IDP05631 ABC transporter, substrate-binding protein [Clostridium difficile 630] CD1979 [Peptoclostridium difficile 630]  ali follow..  13  9..LGLVSVFTLATITGCSSNNNKDKKVTMVLDWTPNTNHTGLFVALYYKEEGLDVEIVQPPESGAE--TLVATGKADFGISYQEQVT--------------------YAKTSEDPLPIKAVATVIQHNTSGFASPKE----KNITTAKDFE-------GKTYGGWGSPSEEA--FKAVMKKNRADFNKLKIVNTGQDDF-------FAAMKTVDFAWIFEGWDAVKDLNFIPVKDLDERLDYYTPLIISNETVLKDNPELAKKFLKATTKGYEYAIKNPEESAKILVKHAPEVDEKLALKS.... 284
18 -10.300IDP05370 putative ABC transporter, substrate-binding protein [Bacillus anthracis str. Ames] BA_5220 [Bacillus anthracis str. Ames]  ali follow..  12  1MKKTALISTSIFGLAACGGKDNDEKKLVVGASNVPHAEIL-EKAKPLLEKKGIELEVK-KFQDYVLPNKSLADKDLDA-------------------------------------QHIPYLEKEIKDKKYEFEAGKIHLEPIGVKSLKEL----PDGATIIMSNSVADHGRKEGILKIKDGVDPVKATPKDIADNPKNLEPGLLPQVYNNKEGDAVLIYAIDTKLNPEKDAIAIESND--SPYANVVAVRKGDKDK-----KEIKELVEVLHSKEIEDF.......................... 256
19 -9.820IDP00471 gene: tbpA; thiamin transporter substrate binding subunit YPO0522 [Yersinia pestis CO92]  ali follow..  7  1MFKHIISCLLLISATSALAAEKPTLTVYTYDSFAADWGPGPAIKQAFEAECDCQLKFVALEDGVSLLNRLRMEGKADVILGLDNNLVQAAEQTGLFTPSQVDTRNLTLPEPWQNKTFVPY-------GYFAFVYNKEKLKN---KSLHELIS-SKEPWKVIYQDPRTSTPGLGLMLWMQKVYGPQAWQQLAQKTVTVTKGWSEAYGLFLKGEADLVLSYTTSPAYKNNNYAAADFSEGHYLQVEVAGQLAAS--KQPELAQRFMQFIVTPAFQNHIPTGNWMYPVIKMDLPAGFETLAVPQTALQ 307
20 -9.260IDP90590 lipoprotein, NLPA family [Campylobacter jejuni subsp. jejuni NCTC 11168] Cj0770c [Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819]  ali follow..  13  1MNIKKIFLSVLFTISL---SFGADKTIIIGATPTPYAEIL-NFSKPLFQEKGWKLIVK-EFNDYNIPNIALNEKDLDANLYQHKPFLDDFNTHKGTKLSSLGAIVLVPMAIYSNSIK----DIKDIPNGAKIAIPNDATNESRALDLLAKANLIEFKSQSTLKTPIDISKNPKKLK--------------------IELKAAQLPRALNDTDLAIITTYALGAGLNPLKDGIFMEDKD--SLYAIVLATRKGEETS-----QKSLVIKEILTSDKIKNF.......................... 245
21 -9.210IDP05714 putative ABC transporter, substrate-binding protein [Bacillus anthracis str. Ames] BA_0175 [Bacillus anthracis str. Ames]  ali follow..  12  1MKKVLLSIVSGAVLLLGAVKALDEKKITVGVTGGPHEQIF-EKVKEVAAKDGLEIDVK-VFNDYVAPNVSLDEKSLDVNSYQTKSYLDVFKAERNMKLTEVFSTVTFPMGVYSKSLK----DVKDLKDGDAIAVPNDPTNERALKLFEKAGVLKVDPKATEKATAKDVIENPKNLK--------------------VELEASQLPTQLSEVKAAAINTFALGAKLSPAKDSIFREGKD--SPYVNWVVVRTENKDD-----AVVNKLKKAYQSKEVKEF.......................... 257
22 -9.040IDP01503 amino acid ABC transporter, periplasmic amino acid-binding protein, putative VCA0978 [Vibrio cholerae O1 biovar El Tor str. N16961]  ali follow..  11  1MMKSIATLISVVLCSF----SAWAQTITAAQDPWPQKGLSVDIVTAAFATQGYTVEFTI-----SRALNDVKEGKIDILPATWFT---------------------------QERTAYLTYSDNYLTNQVKFIKKAG--DNFEFAGLASLN-------GKKVGIVRGY------------GYGDEFMNDPSFFRPEST-DLKQNLQKLQAGRIDLAVEDELVAKSIITEAGMNLADFAFTNQAISENPLHVTSGKANPRSEELVAAFNKGLANGTFDKLLADYGIK................... 243
23 -9.010IDP90739 lipoprotein, NLPA family [Campylobacter jejuni subsp. jejuni NCTC 11168] Cj0772c [Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819]  ali follow..  15  1MKIKSLFIASILTLSL---NANALETITVAATPVPHAEIL-EQVKPDLEKQGYKLEIK-EFTDYVLPNLAVDNGEADANFFQHTPYLEEFNKNKGTKLIKVAAIHIEPMAVYSKK----------------------------YKSLDDIKE------GVKIAIPNDPTNESRALDIIAKKGLVKFKDDNPKKIKFVELKPAQLPRALNDVDFAVINSYALSANLNPAKDSVFIEDKE--SPYANILVVRVGHEND-----PKIKALIQALQSDKIKQF.......................... 244
FFAS is supported by the NIH grant R01-GM087218-01
1 4 7 7 0 1   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Lesley SA, Kuhn P, Godzik A., Deacon AM, Mathews I, Kreusch A, Spraggon G, Klock HE, McMullan D, Shin T, Vincent J, Robb A, Brinen LS, Miller MD, McPhillips TM, Miller MA, Scheibe D, Canaves JM, Guda C, Jaroszewski L, Selby TL, Elsliger MA, Wooley J, Taylor SS, Hodgson KO, Wilson IA, Schultz PG, Stevens RC. Structural genomics of the Thermotoga maritima proteome implemented in a high-throughput structure determination pipeline. Proc Natl Acad Sci U S A. 2002 Sep 3;99(18):11664-9. Epub 2002 Aug 22.