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Query: [R] COG4015 Predicted dinucleotide-utilizing enzyme of the ThiF/HesA family, from COG1018

Results of FFAS03 search in CSGID
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MAVILLEISELEGKKAPRGEVTLVGAGRLGLRTALNLMQIHRGGPERINVIDGQRVSADDLIFRLMGATPGEYKVKFIESLATPGFSRTVRGIPEYIDRDNLHLLRGDVVCVEIAGGDTLPVTAEIIKYAQKRGSATISTMGVFGIGEEEVNAISIEEADPGNPIVEYLLDEGVTDHLLVGTGKLIRDWEPVTPYVLDRVSEVMTAEILKLLRRKLGLast
1 -56.100IDP04735 gene: chlN; molybdopterin biosynthesis protein [Yersinia pestis CO92] YPO1494 [Yersinia pestis CO92]  ali follow..  17  15.QITLRGFDFDGQEKLKAAKVLIVGLGGLGCAAAQYLAA---AGVGHLTLLDFDTVALSNLQRQILHSRIGMTKVASAQTLSEINPHLALNTLDKQLDDEQLLSLIAE-HQLVLDCTDNLSTREQLNRLCHTLGKPLVSGAAIRMEGQVSVFTYQD-----NQPCYRCLSRLFGDT-------ALTCVEAGVMAPLVGIIGNLQAMEAIKLLAN... 214
2 -56.000IDP00940 gene: moeB; molybdopterin biosynthesis protein MoeB STM0845 [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]  ali follow..  19  15.QIILRGFDFEGQEALKDARVLVVGLGGLGCAATQYLAG---AGVGQLTLLDFDTVSVSNLQRQTLHATVGQPKVESADALARINPHITITPVNARLDDDAMTSLIAG-HSLVLDCTDNVSVRNQLNAGCYTAKVPLISGAAIRMEGQVTVFTYRE-----NEPCYRCLSRLFGEN-------ALTCVEAGVMAPLIGVIGSLQAMEAIKLLAH... 214
3 -47.100IDP91765 ThiF family protein [Yersinia pseudotuberculosis IP 32953] YPTB1885 [Yersinia pseudotuberculosis IP 32953]  ali follow..  14  95.HRLFFELSKDNHEALSLATVGIMGTGGIGSNVAILLAA---AGVGKLKISDGDLIEESNLTRATIFDQIGSLKVASLENISERNKTCGVEVLPLLLNEENMDKFFFSECDIIVLSADPNNVFELISIFHDNNNIPIVNAGYLGRLGLIGPMMDAT-----SNPGFKELFTRDCEENRTGKILINRRYQAPSYGPLNYMVSSICSHEVIRYLATR.. 309
4 -8.410IDP92100 malate dehydrogenase, putative [Toxoplasma gondii ME49] TGME49_118430 [Toxoplasma gondii ME49]  ali follow..  13  151...........SFFKMSRRKIGLIGGGNIGATLALLSAV---KELGDVVMFDGKCLDLYQLDADVIIVTAGVPRKPGMSRDDLLAINAKIMG--KQYCPNAFVICITNPLDVMVGVLDSARLRTFLSERL-DTMVPLPRFTTVGGIPLPELVKMGMISQQEVDDIVQRTRNGGGEAAGVLMAEAYLKDRKRVLPYLNGEYGVKDMYVGVPCVIGAGG 435
5 -8.140IDP90552 gene: rfaD; ADP-L-glycero-D-mannoheptose-6-epimerase YPO0058 [Yersinia pestis CO92]  ali follow..  14  2....................IIVTGAGFIGSNIVKALN---NIGYKDILVVDNLKDGTKFVNLVDLDIADYMDKEDFVASIVAGDDMGDIDAIFHEGACSSTTEWDGKYMMDN-----NYQYSKDILHFCLDRSIPFLYASSAATYGGRTDNFIED............................................................. 130
6 -8.080IDP90559 gene: rfaD; ADP-L-glycero-D-mannoheptose-6-epimerase [Vibrio cholerae O1 biovar eltor str. N16961] VC0240 [Vibrio cholerae O1 biovar El Tor str. N16961]  ali follow..  14  2....................IIVTGAGMIGSNIIKALN---ERGITDILVVDHLKNGRKFKNLVDLQIADYMDRDDFLAQIMAGDDFGFIDAIFHEGACSATTEWDGKYVMLN-----NYEYSKELLHYCLDREIPFLYASSAATYGETDT.................................................................. 125
7 -8.050IDP95479 S-adenosylhomocysteinase Q5CPH1 [Cryptosporidium parvum]  ali follow..  13  252.QSLLHGLFNGCIQMLAGKKIVVLGYGEVGKGCAQGLSGVG----ARVIVTEIDPI------CALQASMEGYQVSVLEDVVSEADIFITATGNKDVITVEHMRKMKENAYIANIGHFDD.................................................................................................. 359
8 -7.920IDP02583 3-hydroxyacyl-CoA dehydrogenase/enoyl-CoA hydratase/isomerase family protein [Bacillus anthracis str. `Ames Ancestor`] GBAA5249 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  11  5..................KKAAVLGSGVMGSGIAAHLA---NIGI-PTLLLD---IVPPALTKEEEAKGLTLEHKSVRNRFSNTAVQKLLKQKPAPLTVKGNLALIEADVDWIIEVVENLDIKKKLFE-----KVDAVRKPGSIVSSNTSGISVEKMAEGRSDKLLEVIPTKKTDPQVLSGKGVVIAKDTP--NFIGNRIGTYGLLVTLQEM..... 224
9 -7.650IDP92093 adenosylhomocysteinase, putative [Toxoplasma gondii ME49] TGME49_025050 [Toxoplasma gondii ME49]  ali follow..  16  238.HSLPDGIMRATDVMLGGKRVVICGFGDVGKGCAAAMKGAG----ARVVVTEVDPI------CALQAAMEGYSVSTLESQLATADIFISATGNKDIITARHMSQMKNNAIVGNIGHFDN.................................................................................................. 345
10 -7.510IDP02372 gene: mdh; lactate dehydrogenase [Francisella tularensis subsp. tularensis SCHU S4] FTT0535c [Francisella tularensis subsp. tularensis SCHU S4]  ali follow..  13  1...............MARKKITLVGAGNIGGTLAHLALI---KQLGDVVLFDGKALDLLQTNSDVVIVTAGVPRKPGMSRDDLLGINIKVMQ--KHNCPNAFVICITNPLDIMVGVLDSARFRTFLADE-LNVSVQQVQAYVMGGHGDTMV.................................................................. 181
FFAS is supported by the NIH grant R01-GM087218-01
1 4 7 5 1 8   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Lukasz Jaroszewski, Zhanwen Li, S. Sri Krishna, Constantina Bakolitsa, John Wooley, Ashley M. Deacon, Ian A. Wilson, Adam Godzik, Exploration of Uncharted Regions of the Protein Universe. Plos Biology. 2009 Sep. 7(9):e1000205