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Query: [D] KOG1845 MORC family ATPases, from COG1018

Results of FFAS03 search in CSGID
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MAESGSTNPKSPSVVPDSTLGGLKRDLRNYHDGDDSNNLSIKKSKTTKMENNCREIVPLDVTPLSIVPPDTPKLSRQFWKAGDDDEAAPVPLYCSNDAAVRVHPQFLHANATSHKWALGALAELLDNSLDEVSNGATYVHVDSTINKRDGKSSILIVEDNGGGMNPSTFRECLSLGYSRKRNMANRVGQYGNGFKTSTMRLGADAIVFSRSRGINGNNPTQSIGMLSYTFLYETRKCEAIVPTVDYELVDNKWKEIVYNSTNEWLDNLETILRWSPYLSQQDLLDQFNHLEEQGTRIVIYNLWEDDEGKMELDFDTDPHDIQLRGVNRDEKNIDMAKTYPNSRHFLTYRHSLRSYASILYLKRPDNFRIILRGEDVEHHSVLDDMMKIEEKTYKPMRSPEWPDQEEMVASLKLGFVKDAHHHIDIQGFNVYHKNRLIKPFWRVWNAAGSDGRGVIGILEANFIQPAHNKQGFERTVVLAKLESRLVTHQKNYWSSRCHEIGYAPRRKQKNYESSVTETPRPFNNINVVKGSSSSTPVPVRVFRPNVEPSGRNQIPQVETRERSFDINPEIGAKNRSYYGLGISSFKETGSVNLEAELQKVKQESAKLVSELQRQKQLLELQESKAKIQNLEKAQREKEVLELQLKESKARIQNLENRQEGVSTIFQQERARRDVTEDGLRKKLREASDVIDGLRKQVDTFKGKRILLast
1 -14.700IDP02344 gene: htpG; heat shock protein 90 [Francisella tularensis subsp. tularensis SCHU S4] FTT0356 [Francisella tularensis subsp. tularensis SCHU S4]  ali follow..  13  2.....................................................................................SEKKYTFETEVDKLLHLVIHSLYSNREI-------LRELVSNSSDA-NEDDTDYAIRIDFDKDAK---TITVSDNGIGMTEEEVIENLKSGTKKKSKDNELIGQFGVGFYSSFI-VADKVTVRTRKAGQRGTEVILHIKKEHLDLLEYHVLKGLVTSIQMKKVEYDKDGKQTVKDEYETVNNTKAIWLRSKDEVTDEEYQEFYKYISHDFADALMWIHNKVEGNLE-------------------------------------------YNSLLYIPQNKPFDFWNRDKD--------------------------------------------------YGLSLYVRRVFIMENKELLPP-------VKGVIDSADLPLNVSREILQHNKVIDKIKKAITTKILSELKKLASK--------DKEKYQKFWDSFGQVLKEGVSDDYSNKEKIAGL------------ATTQSGDSKQTVSLADYISRMKEGQDTIYYITSDSYKAAANNPQLEAFKKKGIEVILMTDRIDEWMMSTLTEFDGKHMKSIIKGDIDLDRFETPENKEKFEKEAKDFEKVLKEIKEVLKDKVEDVRLSKRLTDSPSCV................ 541
2 -14.500IDP91391 gene: mutL; DNA mismatch repair protein [Vibrio vulnificus CMCP6] VV1_1292 [Vibrio vulnificus CMCP6]  ali follow..  11  15............................................................................................................AAGEVVERPASVVKELVENSLDSGATKIDI---------EKGGAKLIRIRDNGSGIVKDELGLALSRHATSKIHTLDDLEAIMLGFRLASISSVSRLTLTSRPATQEQAWSAYTEGRDMQVKLQPTAHPI-------------------------------------------------------GTTVEVVD---------------------------------------------------------LFFNTPARRK-FLRTEKTEFAHIDELLKRIALSCFDVSIAAHNDLQAEKRLATVCG-IELEHQGLKLHGWYCYVNGRMMRAIRQSYETSLKPEQFAAYVLFIELVHPAKHEVRFHQARVHDFIYQALASALAQ--SDSIEQPQINESAFHYQAEPEVAPQGSFPAESNEVPQAVYHAIEKAPAYPRKAGQEQQLQPVAPLESSFSSEQGREVSPAPHNERKAWMESRSPARHTTSSNQSERYGEPAPSKQQVKAYAELLHTPDFPSQNVECHPSPSIASPVQETTTKAGCQLISLARAEFYRTLGQLNGDKAPLKSQPLLVPLSLKLEKGLVHAAQEHQDRFAR.... 554
3 -12.200IDP04237 putative sensor histidine kinase [Clostridium perfringens ATCC 13124] CPF_0863 [Clostridium perfringens ATCC 13124]  ali follow..  12  289........................................................................................VNTINLKDITVFIDENADLLETNVNELDFQRIVSNILRNSIEALDGSGSI----KINTYYSFNYFVLKIQNNGPEIPDKILNKIFDSGFTTKENKES--NN-GFGLAIVK-SYNGKIQVSSTDEFTE----------------------TIYLPTIK............................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 420
4 -11.500IDP02529 gene: gyrB; DNA gyrase subunit B [Campylobacter jejuni subsp. jejuni NCTC 11168] Cj0003 [Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819]  ali follow..  20  2..................................................................................QENYGASNIKVLKGLEAVRKRPGYIGDTNIGG--LHHMIYEVVDNSIDEAMAGCDTIDVEI------TTEGSCIVSDNGRGIPLTVVLTVLHAGGKDKDTYKVSGGLHGVGVSVVNA-LSKKLVATVERNGE............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 138
5 -11.300IDP04540 sensor histidine kinase [Clostridium perfringens ATCC 13124] CPF_0511 [Clostridium perfringens ATCC 13124]  ali follow..  18  411....................................................................................................................IVTILGNLIENAFDSCVCSSSYNKEVEVTLYEDDEKIELQVRDNGKPIDNNIKERIFELGVSSKGEGR------GTGLKNRVELYDGCIDIEEFNEEK............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 505
6 -11.200IDP04498 sensor kinase citA [Vibrio cholerae O1 biovar eltor str. N16961] VC0791 [Vibrio cholerae O1 biovar El Tor str. N16961]  ali follow..  18  444....................................................................................................................LAAVLGNLLDNAFEATLKNPHSNKTISLLLTDNGAELVIEVADNGIGISADIAQTLFLKGVSSKNQEGH-----GIGLHQFVTQAHGSILIDSAEPQ............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 538
7 -11.200IDP95120 two-component sensor kinase [Klebsiella pneumoniae subsp. pneumoniae MGH 78578] YP_001333744 [Klebsiella pneumoniae subsp. pneumoniae MGH 78578]  ali follow..  17  423....................................................................................................................LISIIGNLLDNAIEATQRAELPHEPVEVLIQLNARELIIEVADRGVGIRPDIRERIFERGVTTKTR-----GDHGIGLEHYVTQAGGTIEVADNAPR............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 517
8 -11.100IDP04431 sensor histidine kinase [Bacillus anthracis str. `Ames Ancestor`] GBAA5088 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  22  212............................................................................................................KVASDAKWLKFIIYQLMTNAVRYSGERGKKVFLSA---YRNGKDIILEVRDEGVGIPQEDIRRVFEPFYTGKNGRTFGEST-GMGLSKICDYLGHSVKLDSEVG.............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 314
9 -11.000IDP90603 gene: gyrB; DNA gyrase subunit B [Vibrio cholerae O1 biovar eltor str. N16961] VC0015 [Vibrio cholerae O1 biovar El Tor str. N16961]  ali follow..  13  2..................................................................................SNNYDSSSIKVLKGLDAVRKRPGMYIGDTDDGTGLHHMVFEVVDNSIDEALAGCKDIVVTI------HEDNSVSVSDDGRGIPAEVIMTVLHAGGKDDNSYKVSGGLHGVGVSVVNA-LSEKVLLTIYRGGKI----------HSQTYHHGVPQAPL---------------------------------------------AVVGETERTGTTV---------------RFWPSAQTFTNIEFHYDILAKRLREL----------------------SFLNSGVSIKLTDEREEDKKFVTHLNRNKTPIHEKVFHFNQEREDGISVEVAMQWNDGFQENI------YCFTNNI----------PQRDG--------------TH----------LAGFRGALTRTLNNYMDKE----GFSKKAQAATSGDDAREGLTAVVSV----------KVPDPKFSSQTKDKLVSSEVKSAVESAMNEKLADFLAENPSEAKNVCSKIIDAARAREAARKAREMTRRKGALDLAGLPGKLADCQEKDPALSEL----VEGDSAGGSAKQGRNRKNQAILPLKGKILNVEKARFDKMLSSQEVATLITALGCGIGRDEYNPDKLRYHNII 495
10 -10.800IDP90819 gene: gyrB; DNA gyrase subunit B [Yersinia pestis CO92] YPO4094 [Yersinia pestis CO92]  ali follow..  11  2..................................................................................SNTYDSSSIKVLKGLDAVRKRPGMYIGDTDDGTGLHHMVFEVVDNAIDEALAGCKEILVTI------HADNSVSVQDDGRGIPAEVIMTVLHAGGKDDNSYKVSGGLHGVGVSVVNA-LSEKLELVIRREGK----------VHEQTYKMGVPQAPL---------------------------------------------KVVGETEQTGTTVRFWPSFQTFTNNTEFQYEILAKRLRELSFLNSGVSIKLKDKRNDKEDHFHYEGGIKAFVEYL-----NKNKNPIHPKVFYFSTMKDDIGVEVALQWNDGFQENIYCFTNNIPQRDGGTHLVGFRTAMTRTLNSYMDKEGYSKKAKISATGDDAREGLIAVVSVKVPDPKQTKDKLVSSEVKTAVETLMNEKLVEYLLEN------------------------------------------------------------------------------PTDAKIVVGKIIDAARAREAARKAREMTRRKGALDLAGLPGKLADCQERDPALSEL----VEGDSAGGSAKQGRNRKNQAILPLKGKILNVEKARFDKMLSSQEVATLITALGCGIGRDEYNPDKLRYHNII 494
11 -10.800IDP04382 sensor histidine kinase [Clostridium perfringens ATCC 13124] CPF_0116 [Clostridium perfringens ATCC 13124]  ali follow..  20  217............................................................................................................QVYSDSKWIEFILGQIISNSIKYMNKEHKELKIYC---NENSKYVILNIEDNGAGISEKDISRVFDKGFTGENGRKFGKST-GIGLKKLCKKLGLDIKLISEEG.............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 319
12 -10.500IDP04236 sensor histidine kinase [Clostridium perfringens ATCC 13124] CPF_0837 [Clostridium perfringens ATCC 13124]  ali follow..  16  217............................................................................................................KVYSDEKWVEFIINQVINNSIKYSSKNSRV----KIFANKSKNSITLKIKDSGVGIPNKDLGRVFEKGFTGENGRRFTKST-GMGLKNLCDKLGLGLKITSKEN.............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 318
13 -10.400IDP02394 gene: phoQ; sensor protein PhoQ [Yersinia pestis CO92] YPO1633 [Yersinia pestis CO92]  ali follow..  13  269LADLTHSLKTPLAVLQTTLRSLRTGKQTTIEEVEPIMLEQISRISQQIGYYLHRASMRSEHNVLGREIHSVPALLDSLYSA---RKGIALTLDISPEVTFLGEKNDFMEV----------MGNVLENACKYCLEFVEV------TTLHSEKQLTIVVDDDGPGIPENKRQLIFQRGQ---RVDTLRPGQ-GLGLSIGKISIGARMMV................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 473
14 -10.300IDP91358 Signal transduction histidine kinase [Vibrio vulnificus CMCP6] VV1_2848 [Vibrio vulnificus CMCP6]  ali follow..  15  211LEASYPAEVSPLIDDLNALLFHYQELLQRARNHAGNLSHSLKTPLSVLRNEISQLDVESSHKLLPPVEQIQQHIDYHLGRA---RMAGSMNILSVKSNPSERVDAISIAFDKVYA-LDEMLGNLLENSYKWARSQ-----IRVHSTLTSDDQLTLIIEDNGPGIAEEHLTQVLKRGV---RLDETTPGT-GLGLNIGDLTLGLRANL................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 441
15 -10.200IDP04438 gene: cpxA; two component sensor kinase [Yersinia pestis CO92] YPO0073 [Yersinia pestis CO92]  ali follow..  10  242LISDISHELRTPRLQLATALMRRRHGEGKELERIEMEAQRLDSMINDLLVLSRSQHKNELHREPIKADELWSDVLENAQFEAEQMGKTLVVTAPPGPWPLFCNPAALDS----------ALENIVRNALRYSHHHIAV------AFSIDNQGVTIIVDDDGPGVSPEDREQIFRPFYRTDEARDRASGGTGLGLAIVETAVRGWVKAEDSPLG............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 443
16 -10.100IDP04556 putative two-component sensor histidine kinase [Yersinia pestis CO92] YPO3008 [Yersinia pestis CO92]  ali follow..  18  396....................................................................................................................LTQIISNFLSNAEKYASQGKRV----ELIGEQADDRVLIHVRDYGNGIAAKELKAIFQPFYRVKSHITEGVSGTGIGLSQLAASLQGEISVTSNPAGSC........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 493
17 -10.000IDP04572 DNA gyrase subunit B [Bacillus anthracis str. Sterne] BAS0005 [Bacillus anthracis str. Sterne]  ali follow..  19  5...............................................................................QMQENSYDESQIQVLEGLEAVRKRPGYIGSTSGKG--LHHLVWEIVDNSIDEALAGCDEINVSI------EEDNSIRVTDNGRGIPVEVIMTVLHAGGKGGGGYKVSGGLHGVGASVVNA-LSTELEVFVHREGK............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 144
18 -9.500IDP04632 gene: rstB; signal transduction histidine kinase-like protein [Coxiella burnetii RSA 493] CBU_2005 [Coxiella burnetii RSA 493]  ali follow..  12  268..................................................................................SFARDDFADNAKVNLDLVSLVCSLVESMQDMGYNI--AFTNLLNNAIR--AKNVNV------RIQWRQNRVKVLIEDDGPGIAEKELEQVFEPFYRGEHSRSRDTGGVGLGLRDIISDHNGKVILTNRPNG............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 412
19 -9.360IDP04104 gene: rstB; two-component regulatory system, sensor kinase protein [Yersinia pestis CO92] YPO2309 [Yersinia pestis CO92]  ali follow..  19  314.......................................................................................................................VLDNLVNNALRYSHQRLRI------GLWFDGDNACLQVEDDGPGIPPEERTRIFEPFVRLDPSRDRATGGCGLGLHSIALAYQGSISVNTSPLG............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 404
20 -9.340IDP04544 osmolarity sensor protein EnvZ [Vibrio cholerae O1 biovar El Tor str. N16961] VC2713 [Vibrio cholerae O1 biovar El Tor str. N16961]  ali follow..  16  234ISHDIRTPLTRIRLATEMMSPEDSYLAESIISDTEECNQIISQFMDYLKPVNREAFEAVDLND----------IASDVASSEGGYEVQIETELQAGLAPALGNPIAIKR----------SLSNLVVNALRYGNGWVKV----SSGMTADKKLVWLSVEDNGPGIDPSQVNKVFE-----RGDTARGSEGTGLGLKRIVSQHHGAVSVSNRSQG............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 423
21 -9.330IDP02606 gene: gyrB; DNA gyrase subunit B [Listeria monocytogenes EGD-e] lmo0006 [Listeria monocytogenes EGD-e]  ali follow..  18  10...............................................................................QENASDYNEDQIQVLEGLEAVRKRPGYIGSTSQRG--LHHLVWEIVDNAIDEALAGCTEIEITIEADNS------ITVRDNGRGITVEVIFTVLHAGGKGGGGYKVSGGLHGVGASVVNA-LSTSLEVYVHREGQK........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 150
22 -9.240IDP04007 sensor histidine kinase [Vibrio cholerae O1 biovar eltor str. N16961] VC1319 [Vibrio cholerae O1 biovar El Tor str. N16961]  ali follow..  17  318...................................................................................................LDADPQLLTR----------ALVNLIRNAEKYAGDRLLI------EASTVDAKLCIAIHDNGPGIEEQHWPHIFDAFYSTDSSRNKAQSGFGLGLKQIMARHQGEVTLTKSPLG............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 418
23 -9.200IDP01924 gene: cheA; two-component sensor histidine kinase CheA [Listeria monocytogenes EGD-e] lmo0692 [Listeria monocytogenes EGD-e]  ali follow..  17  334.................................................................................................ADTEVDKIVIDEIGD-------PLVHLIRNSVDHGAETVEV----NLKAFHSGNNVVIEIADDGAGINKRKVLELFDSGFSTADQVSDLSGR-GVGLRNTILKIGGKISVESSEAGSTFRIEIPLTLSIIQSMLVATSERRYAVPL............................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 507
24 -9.120IDP04239 sensor histidine kinase [Clostridium perfringens ATCC 13124] CPF_1057 [Clostridium perfringens ATCC 13124]  ali follow..  14  311......................................................................................................................QTARILVENATKYTEEGEI---ITLKVGENSKGEAYFSIQDNGIGMDENDVPHIFERFFRADTARVRKNGGTGLGLSIAK-NHKGYFSVLSRKG.............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 404
25 -9.010IDP04397 sensor histidine kinase [Bacillus anthracis str. `Ames Ancestor`] GBAA3230 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  16  281.......................................................................SALISQLLLLARADQGNDNTFQFECINMSELTEIVVEELSLMVQ-MMRLLMNLLTNAIAYSKANGTV----HMQLFRDETNIIGKVSDNGIGISEQHITKIWRFYRVDAARTSSNIGNTGLGLKWIVELHGGEITVESGLG.............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 442
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Igarashi Y, Eroshkin A, Gramatikova S, Gramatikoff K, Zhang Y, Smith JW,Osterman AL, Godzik A. CutDB: a proteolytic event database. Nucleic Acids Res. 2007 Jan;35(Database issue):D546-9. Epub 2006 Nov 16.