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Query: [L] COG0592 DNA polymerase sliding clamp subunit (PCNA homolog), from COG1018

Results of FFAS03 search in H.sapiens
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MKFVVSRNELGNLIKKIQSVVPQNTPIPVLTHVLIETYNDELVFTATDLTVSTRCVTKAKVYEKGAISIPSKRFFQLVKELTEANLEISSSAGEMAQITSGSSCFRLLSMEKEDFPMLPDIQNALRFSLPAEQLKTMLQRTSFAVSREESRYVLTGVLLAIANGVATIVGTDGKRLAKIDAEVTLDKSFSGEYIIPIKAVEEIIKMCSDEGEAAIFLDQDKIAVECDNTLLITKLLSGEFPDFSPVISTESNVKLDLHREELITLLKQVALFTNESSHSVKFSFLPGELTLTANCTKVGEGKVSMAVNYSGELLEIAFNPFFFLDILKHSKDELVSLGISDSYNPGIITDSASGLFVIMPMRLHDDLast
1 -11.600sp|P12004|PCNA_HUMAN Proliferating cell nuclear antigen OS=Homo sapiens GN=PCNA PE=1 SV=1  ali follow..  10  5.......................................................................................................................................RLVQGSILKKVLEALKDLINEACWDISSSGVNLQSMDSSHVSLVQLTLRSEGDRNLAMGVNLTSMSKILKCAGNEDIITLRAEDNADTLALV-SDYEMKLMDLDVEQLG-IPEQEYSCVVKMPSGEFARICRDLSHIGDA----VVISCAKDGVKFSASGTSNVDKEEEAVTIEMNEPVQLTFALRYLNFFTKATPSSTVTLSMSADVPLVVIADMGHLKYYLAPKIEDEE 259
2 -10.100sp|Q6WBX8|RAD9B_HUMAN Cell cycle checkpoint control protein RAD9B OS=Homo sapiens GN=RAD9B PE=1 SV=2  ali follow..  12  3.............................................................................................................................KCVMSGSQVK-VFGKAVQALSR-----ISDEFWLDPSKKGLALRCVNSSRSAYGCVLFSPVTTLHLKCKLGMKSILPIFRCLNSLERIFTRSDKCKVVIQFFYRHGIKRTHNICFQESQPL-KNVCTNTLMIQPRLLADAIVLFTSSQEE----VTLAVTPLNFCLKSSNEESMDLSNAVHSEMFGMDTEITFCFKELKGILTFSEHAPISIYFDFPGKPLALSIDDMLVEANFILATLAD 275
3 -7.740sp|Q99638|RAD9A_HUMAN Cell cycle checkpoint control protein RAD9A OS=Homo sapiens GN=RAD9A PE=1 SV=1  ali follow..  12  2.............................................................................................................................KCLVTGGNVK-VLGKAVHSLSR-----IGDELYLEPLEDGLSLRTVNSSRSAYACFQAATPGQDLLRCKILMKSFLSVFRSLAMLECISLNGRSSRLVVQLHCKFGVRKTHNLSFQDCESL-PASCPHMLRAPARVLGEAVLPFSPALAE----VTLGIGRGRRVILRSYHEEEADSTAKAMVTEQEGVAITFCLKEFRGLLSFAENLNLSIHFDAPGRPAIFTIKDSLLDGHFVLATLSD 267
4 -5.450sp|Q9HCE1|MOV10_HUMAN Putative helicase MOV-10 OS=Homo sapiens GN=MOV10 PE=1 SV=2  ali   8  14...............................................................................................................GQCF--ESFLVVRGLDMETDRERLRTIYNRDFKISFGTPAPGFSSMLYGMKIANLAYVTKTRVRFFRLDRMKLGSDISKHHKSLLAKIFYDRAEYLHGKHGVDVEVQGP---HEARDGQLLIRLDLNRKEVLTLRLRNGGTQSVTLTHLFPLCRTPQFAFYNEDQELPCPLGPGECELHVHCKTSFVGYFPATVLWELLGPG-GSEGAGTFYIARFLAAVAHSPLAAQLKPMTP..................... 255
5 -5.310sp|Q2LD37|K1109_HUMAN Uncharacterized protein KIAA1109 OS=Homo sapiens GN=KIAA1109 PE=1 SV=2  ali   12  27.................................................................................PCWGLDIVCGKGTDFNY-ADRQRDCLQVLKVSEIAQPGRPRQILAFELRMNIIADATIDLLFTKNRETNAVHVNGSYLEINIPMTVEENGYTPAIKGQLLHVDATTSMQYRTLLEAEMLAFHINA-PQTWQCELEVYKATYHFIFAQKNFFTDLIQDSPPDIFSFVPYTWNFKIMFHQFEMIWAANQHNWIDCQENVYLAACGETLNIDFSLPFTDFVPATCNTKFSLRGEDVDLHLF............................................... 293
6 -5.080sp|O60671|RAD1_HUMAN Cell cycle checkpoint protein RAD1 OS=Homo sapiens GN=RAD1 PE=1 SV=1  ali follow..  12  25.....................................................................................................................................................................................................RNLSTILKAIHFREHATCFATKNGIKVTVENVQANAFIQAGIFQEFK----QEESVTFRINLTVLLDCLSIFG--MPGTLTALRMCYQGYGYPLMLFLEEGGEETLDFDFCSTNVINKIILQSEGLREAFSELDSEVLQITMSPDKPYFRLSTFGNAGSSHLDYPKDSD 208
7 -4.800sp|Q2LD37|K1109_HUMAN Uncharacterized protein KIAA1109 OS=Homo sapiens GN=KIAA1109 PE=1 SV=2  ali   12  28...................................................................................................................................................................................................................QCELEVYKATYHFIFAQKNFFTDLIQDSPPDIFSFVPYTWNFKIMFHQFEMIWAANQHNWIDCQENVYLAACGETLNIDFSLPFTDFVPATCNTKFSLRGEDVDLHLF............................................... 143
8 -4.760sp|Q13472|TOP3A_HUMAN DNA topoisomerase 3-alpha OS=Homo sapiens GN=TOP3A PE=1 SV=1  ali   11  2...LCVEDPMATVVEVRSKPKSKWRPQALDTVELEKLASRKLRINAKE-----TMRIAEKLYTQGYISYPRTETNIFPRDLNLTVLVEQQTPDPRWGLERGGPTPRNGNKSDQAHPPIHPTKYTNNLQGDEQRLYEFIVRHFLACCSQDAQGQETTVEIDIAQERFV---AHGLMILARNYLDVYPYDHWSDKILPVYEQGSHFQPSTTEADLIALMEKHGIGTDATHAEHIETIKARMY-PDKRFLPGHLGMGLVEGYDSMGYEMSKPDLRAELEADLKLIC................................................................................... 296
9 -4.750sp|P23467|PTPRB_HUMAN(removed signalp:1-22) Receptor-type tyrosine-protein phosphatase beta OS=Homo sapiens GN=PTPRB PE=1 SV=3  ali   8  87..ITTESEPLFGAIEGVSAGLFLIGMLVAVVALLICRQKVSHGRERPSARLSIRRDRPLSVHLNLGQKGNRKTSCPIINQFEGHFMKLQADSNYLLS---------------KEYEELKDVGRNQSCDIALLPENRGKNRYNNILPYDATRVKLSNVDDDPCSDYINASYIPGNNFRREYIVTQGPLP---------GTKDDFWKMVWEQNVHNI--------------VMVTQCVEKGRVKCDHYWPADQDS................................................................................................................. 300
10 -4.640sp|Q9NQ31|BCA3_HUMAN Proline-rich protein BCA3 OS=Homo sapiens GN=BCA3 PE=1 SV=2  ali follow..  19  164................................................................................................................................................................................................................................................................................AENISKDLYIEVYPGTYSVTVGSNDLTKKTHVVAVD-SGQSVDLVFP............................................... 209
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Li W, Godzik A. cd-hit: a fast program for clustering and comparing large sets of protein or nucleotide sequences. Bioinformatics. 2006 May 26;