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Query: [C] COG1145 Ferredoxin, from COG1018

Results of FFAS03 search in H.sapiens
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MHHSHHLEIYEKLREKLNKAPIGLPKTVSGVEKELLSVLFDEEEAKIAVHMPFIRFTAEQLAERTGKSLEYVEKILNEMAKKGTVWKGEKDGQTYYRLFPVIVGFAETPFWPGPGKDPRQEKLARLWSQYRKEGFLDEIGDREHPIMRALPERDTISEKSEILPYEDAVKLVKERDYIAVGYCPCRVMARLVGEGCRHSIENCIHMGSVGKYMVEHGLGRRISADEAIEILRQSNREGLVHLTERSKHVATICNCCSDCCVFFKAVHEAKHPNTIAHSSYLATVDTSRCIACGICMLRCPMKAIKAKINREPASVDAEKCLGCGVCVPTCPMEAIELVERDELLELPDGMTYVQELLADKGRDPSGLFLast
1 -24.300sp|Q12882|DPYD_HUMAN Dihydropyrimidine dehydrogenase [NADP+] OS=Homo sapiens GN=DPYD PE=1 SV=2  ali   26  190...................................................................................................................................................................................................................................................................................NVEQVVAMIDEEMCINCGKCYMTCNDSGYQAFDPETHLPTITDTCTGCTLCLSVCPVDCIKMVSRTT.......................... 259
2 -23.700sp|O00217|NDUS8_HUMAN(removed signalp:1-19) NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial OS=Homo sapiens GN=NDUFS8 PE=1 SV=1  ali follow..  31  86..........................................................................................................................................................................................................................................................................................PSGEERCIACKLCEAICPAQAITIEAEPRRYDIDMTKCIYCGFCQEACPVDAIVEGPNFEFSTETHE................... 160
3 -21.200sp|Q16134|ETFD_HUMAN Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial OS=Homo sapiens GN=ETFDH PE=1 SV=2  ali   17  87..................................................................................................................................................................................................................................................................................LTLRDDSIPVNRNLSIYDGPEQRFCPAGVYEFVPVEQRLQINAQNCVHCKTCDIKDPSQNINWVVPEG.......................... 158
4 -15.200sp|P21912|DHSB_HUMAN(removed signalp:1-15) Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial OS=Homo sapiens GN=SDHB PE=1 SV=3  ali follow..  17  157..................................................................................................................................................................................................................................................................................QSIEEREKLDGLYECILCACCSTSCPSYWWNGDKYLGPAVLMQARCHTIMNCTRTCPKG----------LNPGKAIAEIKKMMATYK....... 259
5 -14.900sp|Q9UHQ1|NARF_HUMAN Nuclear prelamin A recognition factor OS=Homo sapiens GN=NARF PE=1 SV=1  ali follow..  12  2...............................................................................................................................................................................................................................................................................................KCEHCTRKECSKKTKTDDQENKLADAKIFLSDCLACDSCMTAEEGVQLSQQNAKDFFRVLNLTSKHKVLVVSVCPQSLPYF 106
6 -14.800sp|Q9H6Q4|NARFL_HUMAN Cytosolic Fe-S cluster assembly factor NARFL OS=Homo sapiens GN=NARFL PE=1 SV=1  ali follow..  13  1..........................................................................................................................................................................................................................................................................MASPFSGALQLTDLDDFIPSQECIKPVKVEKRAGSGVAKIRRRLEKAKVSLNDCLACSGCITSAETVLITQQSHEELKNKMAAPSQQRLVVVSVSPQSRASL 124
7 -13.600sp|P04626|ERBB2_HUMAN(removed signalp:1-22) Receptor tyrosine-protein kinase erbB-2 OS=Homo sapiens GN=ERBB2 PE=1 SV=1  ali   12  1............................................TQVCTGTDMKLRLPASPETHLDMLRHLYQGCQVVQGNLELTYLPTNASLSFLQDIQEVQGYV--LIAHNQVRQVPLQRLRIV-TQLFEDNYALAVLDNGDPLNNTTPVTGASPGGLRELQLRSLTEILKGGVLIQRNPQLCYQDTDIFHKNNQLALTLIDTNRSRACHPCSPMCKGSRCWGESSEDCQSLTRTVCAGGCARCKGPLPTDCCHEQCAAGCTG-------------------KHSDCLACGICELHCPALVTYNTDNPEGRYTFGASCVACGSCTLVCPLHNQEV............................... 300
8 -13.100sp|Q92794|MYST3_HUMAN Histone acetyltransferase MYST3 OS=Homo sapiens GN=MYST3 PE=1 SV=2  ali   14  1MVKLANPLYTEWILEAIKK---------------VKKQKQRPSEERIC----------NAVSSSHGLDRKTVLEQLELSVKDGTILKVSNKGLNSYKDPDNPGRIALPKPRNHGKLDNKQNVDWNKLIKRAVEGLAESGGSTLKSIERFLKGQKDVSALFGGSAASGFHQQLRLAIKRAIGHGRLLKDGPLYRLNTKATNVDGKESCESLSCLPPVSLLPHEKDKPVAEPIPICSFCLGTKEQNREKKPEELISCADCGNSGHPSCLKFSPELTVRVKALR------QCIECKTC-SSC-----------RDQGKNADNMLFCDSC-MECCDPPLT................................ 298
9 -12.900sp|Q15303|ERBB4_HUMAN(removed signalp:1-25) Receptor tyrosine-protein kinase erbB-4 OS=Homo sapiens GN=ERBB4 PE=1 SV=1  ali   21  248............................................................................................................................................................................................................................................................................................GPDNCTKCPNCVEKCPDGLQGANSFIFKYADPDRECHPCPNCTQGC...................................... 300
10 -12.700sp|P06213|INSR_HUMAN(removed signalp:1-27) Insulin receptor OS=Homo sapiens GN=INSR PE=1 SV=4  ali   12  9.................................................................................PGMDIRNNLTRLHELENCSVIEGHLQILLMFKTRPEDFRDLSFPKLIMITDYLLLFRVYGLESPNLTVIRGSRLFFNYALVLGLYNLMNITRGSVRIEKNNELCDSVEDNYIVLNKDDNEECGDICPGTAKGKTNCPATVINGQFVERCWTHSHCQKVCPTICKSHGCTAEGLCCHSECLGNCSQPD----------------DPTKCVACGRCVETCPPPYYH---FQDWRCVNFSFCQDLNKCIPECPSG................................... 291
11 -12.400sp|P21860|ERBB3_HUMAN(removed signalp:1-19) Receptor tyrosine-protein kinase erbB-3 OS=Homo sapiens GN=ERBB3 PE=1 SV=1  ali   13  7....................................................................QAVCPGTLNGLSVTGDAENQYQTLYKLYERCEVVMGNLEIVLTGHNADLSFLQWIREVTG--YVLVAMNEFSTLPLPNLRVVRGTQVYDGKFAILRLTQLTEILSGGVYIEKNDKLCHMDTIDWRDIVRDRDAEIVVKDNGRSCPPCHEVCKGRCWGPGSEDCQTLTKTICAPQCNGHCFGPNPNQCCHDECAGGCS-------------------QDTDCFACGACVPRCPQPLVYEPNPHTKYQYGGVCVASCTSCVRACPPDKME................................ 292
12 -12.100sp|P01266|THYG_HUMAN(removed signalp:1-19) Thyroglobulin OS=Homo sapiens GN=TG PE=1 SV=5  ali   24  233.........................................................................................................................................................................................................................................................................................ASQDGLGCVKCEECIP-CPVGFYQEQAGS-------LACVPCGACVTDCQRNEA................................. 300
13 -12.000sp|A8MWY0|K132L_HUMAN UPF0577 protein KIAA1324-like OS=Homo sapiens GN=KIAA1324L PE=2 SV=2  ali   25  1.............................................................................................................................................................................................................................................................................................ASSCRACSSCVP-CPPGHYIEKET--------NQCKECDTCIP-CGPGSKN................................ 63
14 -11.800sp|Q92824|PCSK5_HUMAN(removed signalp:1-32) Proprotein convertase subtilisin/kexin type 5 OS=Homo sapiens GN=PCSK5 PE=2 SV=3  ali   18  218............................................................................................................................................................................................................................................................................................HGDQCMSCNSCVTHCPDGSYQDTKKNLKTCTEFHNCTECSRCSVSCEDG................................... 292
15 -11.600sp|Q7LFL8|CXXC5_HUMAN CXXC-type zinc finger protein 5 OS=Homo sapiens GN=CXXC5 PE=2 SV=1  ali follow..  20  256............................................................................................................................................................................................................................................................................................GKKKRKRCGMC-APC---------------RRRINCEQCSSCRQICKFKCEELKKKPSA......................... 305
16 -11.600sp|P28331|NDUS1_HUMAN NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial OS=Homo sapiens GN=NDUFS1 PE=1 SV=3  ali   19  18........................................................................................................................................................................................................................................................................................LVKTIMTRCIQCTRCIRFASVDDLGTTGRGNDMQVGT-MSELSGNIIDICPVGALT................................ 82
17 -11.500sp|P00533|EGFR_HUMAN(removed signalp:1-24) Epidermal growth factor receptor OS=Homo sapiens GN=EGFR PE=1 SV=2  ali   14  5....................................................................................................................................................................................................................................KLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGC-------------------EPRDCVSCSECIQ-CHPECLPQAMNITCTGRGPDNCIQCPHCVKTCPAGVM................................. 126
18 -11.400sp|Q9UMN6|MLL4_HUMAN Histone-lysine N-methyltransferase MLL4 OS=Homo sapiens GN=WBP7 PE=1 SV=1  ali   22  212............................................................................................................................................................................................................................................................................................RMARCGHCRGCLRVC------------------GSCVNCGCCVRKCDKIEAR................................ 261
19 -11.300sp|Q9H2H0|CXXC4_HUMAN CXXC-type zinc finger protein 4 OS=Homo sapiens GN=CXXC4 PE=2 SV=1  ali follow..  17  132............................................................................................................................................................................................................................................................................................AKKKRKRCGVC-VPC---------------KRLINCGVCSSCRQIC-RKCEELKKKPG--------TSLERTPVPSAEAFRWFF 198
20 -11.200sp|Q4LDE5|SVEP1_HUMAN(removed signalp:1-17) Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 OS=Homo sapiens GN=SVEP1 PE=1 SV=3  ali   14  225.........................................................................................................................................................................................................................................................................................SVLRGRMCVNCFTCES-CRIGSYQDEEGQ-------LECKLCHSCKAQCKQGTYS................................ 295
21 -11.200sp|P14616|INSRR_HUMAN(removed signalp:1-23) Insulin receptor-related protein OS=Homo sapiens GN=INSRR PE=2 SV=2  ali   11  8.................................................................................PSLDIRSEVAELRQLENCSVVEGHLQILLMFTATGEDFRGLSFPRLTQVTDYLLLFRVYGLESPNLAVIRGTRLFLGYALVVALPALGAVLRGAVRVEKNQELCHLSTIDWGLLQPAPGANHIVGNKLGEECADV------CPGVLGAAGEPCAKTTFSGHTDYRCWTSSHCQRVCPCPHGMACTARGECCHTECLGGCSQPEDPRACVACGACLWACPPGTYQYESW---------RCVTAGSCLAQCPSGFTR................................ 287
22 -11.200sp|P08069|IGF1R_HUMAN(removed signalp:1-30) Insulin-like growth factor 1 receptor OS=Homo sapiens GN=IGF1R PE=1 SV=1  ali   27  214............................................................................................................................................................................................................................................................................................NDTACVACGVCVPACPPNTYRFEGWSEGFVIHDGECMQCIPCEGPCPK.................................... 300
23 -11.100sp|Q6UXX9|RSPO2_HUMAN(removed signalp:1-21) R-spondin-2 OS=Homo sapiens GN=RSPO2 PE=1 SV=2  ali follow..  23  27............................................................................................................................................................................................................................................................................................KDNGCSRCGECLHSCPSGYYGHRAPDMNRCASKDFCTKCGRCFDECPDGFAP................................ 113
24 -11.100sp|Q15303|ERBB4_HUMAN(removed signalp:1-25) Receptor tyrosine-protein kinase erbB-4 OS=Homo sapiens GN=ERBB4 PE=1 SV=1  ali   11  1....................................................................QSVCAGTENKLSSLSDLEQQYRALRKYYENCEVVMGNLEITSIEHNRDLSFLRSVREVTG--YVLVALNQFRYLPLENLRIIRGTKLYEDRYALLGLKNLTEILNGGVYVDQNKFLCYADTQDIVRNPWPSNLTLVSTNGSSGCGRCHKSCTGRCWGPTENHCQTLTRTVCAEQCDGRCYGPYVSDCCHRECAGGCS-------------------KDTDCFACGACVTQCPQTFVYEHNFNAKYTYGAFCVKKCSSCVRACPSSKMEVEENG........................... 294
25 -11.000sp|Q8WYB5|MYST4_HUMAN Histone acetyltransferase MYST4 OS=Homo sapiens GN=MYST4 PE=1 SV=3  ali   16  1MVKLANPLYTEWILEAIQK---------------IKKQKQRPSEERIC----------HAVSTSHGLDKKTVSEQLELSVQDGSVLKVTNKGLASYKDPDNPGRFSSVKPGTFPKSAKGSRGSCNDLRN--------------VDWNKLLRRAIEGLEEPNGSSLKNIEKYLRSQSDLTSTT---PAFQQRLRLGAKRAVNNGRLLKDGPQYRVNYGSLDGKGAPQYPSAFPSSLPPVSLLPHEKDQPRADPIPICSFCLGTKESNREKKPEELLS------------CADCGSCLKFCPELTTNVKALR--------QCIECKTC-SACRVQG.................................. 279
26 -11.000sp|O43149|ZZEF1_HUMAN Zinc finger ZZ-type and EF-hand domain-containing protein 1 OS=Homo sapiens GN=ZZEF1 PE=1 SV=6  ali   21  2............................................................................................................................................................................................................................................................................................DMDLCKTC-TC-DHCQGLIIGRR-----------NCNVCDLC-YGC...................................... 58
27 -10.900sp|Q9YNA8|GAK3_HUMAN HERV-K_19q12 provirus ancestral Gag polyprotein OS=Homo sapiens PE=1 SV=3  ali   7  13.......KMLKDMKEGVKQYGPNSPYMRTLLDSIAHGHRLIPYDWEILAKSSLSPSQVQEQVRRNRAANPPVNIDADQLLGIGQNWSTISQQALM-------------NEAIEQVRAICLRAWEKIQDPGSTCPSFNTVRQGSKEPYPDF-VARLQDVAQKSIAIEKARKVIVELMAYENPNPECQSAIKPLKGKVPAGSDVISEYVKACDGMGGAMHKAMLMAQAITGVVLGGQVRT----------------------------------------------FGGKCYNCGQ-KKNCPVLN-ITIQATTTGREPPDLCPRCKK-ASQCRSK................................... 298
28 -10.900sp|P29122|PCSK6_HUMAN Proprotein convertase subtilisin/kexin type 6 OS=Homo sapiens GN=PCSK6 PE=1 SV=1  ali   13  107............................................................................................................................................................PNADQCLNCVHFSLGSVKTSRKCVSVCPLGYFGDTAARRCRRCHKGCETCSSRAATQCLSCRRGFYHHQEMNTCVTLCPAG------FYADESQKNCLKCHPSCKKCVD-------------------EPEKCTVCGSCIPDCEPGTYFDSELIRCGECHHEECIHCWKCVPACGEGFYP................................ 287
29 -10.900sp|A6NFK2|GRCR2_HUMAN Glutaredoxin domain-containing cysteine-rich protein 2 OS=Homo sapiens GN=GRXCR2 PE=3 SV=1  ali follow..  27  194.............................................................................................................................................................................................................................................................................................EDSCFHCRTC-SLCHGSKFSMLANRFKESYRALRCPACGLC-QICNQ.................................... 248
30 -10.800sp|Q15303|ERBB4_HUMAN(removed signalp:1-25) Receptor tyrosine-protein kinase erbB-4 OS=Homo sapiens GN=ERBB4 PE=1 SV=1  ali   12  1....................................................................................................................................................................................................................................TLFSTINQRIVIRDNRKAENCTAEGMVCNHLCSSDGC-------------------GPDQCLSCRICIESCNLYDGEFREFENGSICGPDNCTKCPNCVEKCPDGLQG................................ 124
31 -10.800sp|O43900|PRIC3_HUMAN Prickle-like protein 3 OS=Homo sapiens GN=PRICKLE3 PE=1 SV=2  ali   10  1...............................................................................................................................................................................................................................................................................................ACEYCDGCGEHIGLDQGQMAYEGQHWHASDR-CFCCSRCGRACSRACSLGSEPTAPGPSRRSWSAGPVTAPLAAST..... 95
32 -10.800sp|Q8NFU7|TET1_HUMAN Methylcytosine dioxygenase TET1 OS=Homo sapiens GN=TET1 PE=1 SV=2  ali   16  125...................................................................................................................................................................................................................................................................................SYTTLLPTLEKKKRKRCGVC-EPC---------------QQKTNCGECTYCKQIC-RKCEELKKKPSVVVPLEVIKENKRPQREKKPKV.... 204
33 -10.800sp|Q16134|ETFD_HUMAN Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial OS=Homo sapiens GN=ETFDH PE=1 SV=2  ali   19  233....................................................................................................................................................................................................................................................................................QPAHLTLRDDSIPVNDGPEQRFCPAGVYEFVPVEQRLQINAQNCVHCKTCDIKDPSQ................................... 299
34 -10.800sp|Q2MKA7|RSPO1_HUMAN(removed signalp:1-20) R-spondin-1 OS=Homo sapiens GN=RSPO1 PE=2 SV=1  ali follow..  20  13........................................................................................................................................................................................................................................................SAEGSQACAKGCELCS--------------------EVNGCLKCGVCLPSCPPGYFDARNPDMEACFSHNFCTKCGRCYPACPEGSSA................................ 115
35 -10.800sp|Q03164|MLL1_HUMAN Histone-lysine N-methyltransferase MLL OS=Homo sapiens GN=MLL PE=1 SV=5  ali   22  252.............................................................................................................................................................................................................................................................................................SRRCGQCPGCQVPC------------------GVCTNCGCCKRKCQN.................................... 296
36 -10.700sp|Q15303|ERBB4_HUMAN(removed signalp:1-25) Receptor tyrosine-protein kinase erbB-4 OS=Homo sapiens GN=ERBB4 PE=1 SV=1  ali   16  1..................................................................................................................................................................................................................................................TLVSTNGSSGCGRCHKSCTGRC--------------------TENHCQTLTVCAEQCDGRCY----GPYVSDCCHRECAGGGACVTQCPQTFVY................................ 93
37 -10.700sp|P08069|IGF1R_HUMAN(removed signalp:1-30) Insulin-like growth factor 1 receptor OS=Homo sapiens GN=IGF1R PE=1 SV=1  ali   23  35...............................................................................................................................................................................................................................................................CPSTCGKRACTENNECCHPECLGSCSAPDNDTACVACGVCVPACPPNTYR---FEGWRCVDRDFCANIGECMQECPSGFIR................................ 133
38 -10.700sp|P62683|GAK1_HUMAN HERV-K_12q14.1 provirus ancestral Gag polyprotein OS=Homo sapiens PE=1 SV=2  ali   7  13.......KMLKDMKEGVKQYGPNSPYMRTLLDSIAHGHRLIPYDWEILAKSSLLPDGVQEQVQRNRAANPPVNIDADQLLGIGQNWSTISQQALM-------------NEAIEQVRAICLRAWEKIQDPGSTCPSFNTVRQSSKEPYPDF-VARLQDVAQKSIADEKARKVIVELMAYENANPECQSAIKPLKGKVPAGSDVISEYVKACDGIGGAMHKAMLMAQAITGVVLGGQVRT----------------------------------------------FGGKCYNCGQ-KKNCPVLN-ITIQATTTGREPPDLCPRCKK-ASQCRSK................................... 298
39 -10.600sp|Q6UXG2|K1324_HUMAN(removed signalp:1-41) UPF0577 protein KIAA1324 OS=Homo sapiens GN=KIAA1324 PE=2 SV=2  ali   10  1.....................................................................................................................................................................KEVARITFVFETLCSVNCELYFMVGVNSRTNT-------PVETWKGSKGKQSYTYIIEENTTTSFTWAFQRTTFHEASRKYTNDVAKIYSIN------VTNVMNGVASYCRPCALEASDVGSSCTSCGTCHS-CPTNTILKAHQP----YGVQACVPCGLCYNDCTFSR.................................. 171
40 -10.600sp|Q8IXZ2|ZC3H3_HUMAN Zinc finger CCCH domain-containing protein 3 OS=Homo sapiens GN=ZC3H3 PE=1 SV=3  ali   23  209..................................................................................................................................................................................................................................................................................IRQARQRREKRKEYCNRFGRCNRRCPY-AVCTRFVRGTCKKTDGTC--CGICSSNCPYSHVYV............................... 299
41 -10.600sp|P21860|ERBB3_HUMAN(removed signalp:1-19) Receptor tyrosine-protein kinase erbB-3 OS=Homo sapiens GN=ERBB3 PE=1 SV=1  ali   23  3.....................................................................................................................................................................................................................................................................................AEIVVKDNGRSCPPCTICAPQCNGHCF----GPNPNQCCHDECAGGGACVPRCPQPLVY................................ 96
42 -10.600sp|O14594|NCAN_HUMAN(removed signalp:1-22) Neurocan core protein OS=Homo sapiens GN=NCAN PE=2 SV=3  ali   26  229.....................................................................................................................................................................................................................................................................................NAGAEEVHSDPCENCGTCNASCDQG------AGENCEIDIDDCLCCGTCIDVC...................................... 298
43 -10.600sp|Q2I0M5|RSPO4_HUMAN(removed signalp:1-19) R-spondin-4 OS=Homo sapiens GN=RSPO4 PE=1 SV=2  ali follow..  26  24............................................................................................................................................................................................................................................................................................EENGCSTCGKCLHDCPPGYFGIRGQEVESCFSQDFCIRCGKCLPTCPPGTLA................................ 109
44 -10.600sp|P00533|EGFR_HUMAN(removed signalp:1-24) Epidermal growth factor receptor OS=Homo sapiens GN=EGFR PE=1 SV=2  ali   10  5.....................................................................KVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERI----ENLQIIRGNMYYENSYALLPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTG-------------------RESDCLVCATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVV................................ 277
45 -10.500sp|P63145|GAK11_HUMAN HERV-K_22q11.21 provirus ancestral Gag polyprotein OS=Homo sapiens PE=1 SV=2  ali   9  13.......KMLKDMKEGVKQYGPN-----SPYMRTLLDSIAYGHRL--------IPYDWEILAKSSLSPSQFLKTWWIDGVQEQVRRNRAANPPVNIDADQLLGI------GQNWSTISQQALMQNEAIEQVRAICLRAWEKIQDPGSACPSFNTVRQG-----SKEPYPDFVARLQDVA---------------------------KSIADEKARKVIVELMAYENANPECQSAIKPLKGKVPAGSDVISEYVKACDGIGGAMHKAMLMAQAITGVVLGGQVRTFGGKCYNCGQ-KKNCPVLN-ITIQATTTGREPPDLCPRCKK-ASQCRSK................................... 298
46 -10.500sp|P87889|GAK10_HUMAN HERV-K_5q33.3 provirus ancestral Gag polyprotein OS=Homo sapiens PE=1 SV=4  ali   7  13.......KMLKDMKEGVKQYGPNSPYMRTLLDSIAYGHRLIPYDWEILAKSSLSPSQVQEQVRRNRAANPPVNIDADQLLGIGQNWSTISQQALM-------------NEAIEQVRAICLRAWEKIQDPGSTCPSFNTVRQGSKEPYPDF-VARLQDVAQKSIADEKAGKVIVELMAYENANPECQSAIKPLKGKVPAGSDVISEYVKACDGIGGAMHKAMLMAQAITGVVLGGQVRT----------------------------------------------FGGKCYNCGQ-KKNCPVLN-ITIQATTTGREPPDLCPRCKK-ASQCRSK................................... 298
47 -10.500sp|Q8NHM5|KDM2B_HUMAN Lysine-specific demethylase 2B OS=Homo sapiens GN=KDM2B PE=1 SV=1  ali   19  1....................................................................................................................................................................................................................................................................................RTTAGARRRRTRCRKCEACLRTC------------------GECHFCGSCIRQCIAPVLP................................ 57
48 -10.500sp|Q7LDI9|GAK2_HUMAN HERV-K_7p22.1 provirus ancestral Gag polyprotein OS=Homo sapiens GN=ERVK6 PE=1 SV=3  ali   7  13.......KKLKDMKEGVKQYGPNSPYMRTLLDSIAHGHRLIPYDWEILAKSSLSPDGVQEQVRRNRAANPPVNIDADQLLGIGQNWSTISQQALM-------------NEAIEQVRAICLRAWEKIQDPGSTCPSFNTVRQGSKEPYPDF-VARLQDVAQKSIADEKARKVIVELMAYENANPECQSAIKPLKGKVPAGSDVISEYVKACDGIGGAMHKAMLMAQAITGVVLGGQVRT----------------------------------------------FGRKCYNCGQ-KKNCPVLN-ITIQATTTGREPPDLCPRCKK-ASQCRSK................................... 298
49 -10.500sp|Q9UKN8|TF3C4_HUMAN General transcription factor 3C polypeptide 4 OS=Homo sapiens GN=GTF3C4 PE=1 SV=2  ali   15  134...................................................................................................................................................................................................................................................................................ISKKMNKQTFPEHCSLCKECSNRCFLTYQSCQS------LIYRRCLLHDPCP--CDSPVF................................. 222
50 -10.500sp|P63126|GAK4_HUMAN HERV-K_6q14.1 provirus ancestral Gag polyprotein OS=Homo sapiens PE=1 SV=2  ali   8  4....................................EARYKSFSIKILKDM-------KEGVKQYGPNSPYMRTLLDSIAHGHRLIPYD-----WEILAKSSLSPSQFLQFKTWWIDGVQEQVRRNRAANPPVNIDADQLLGIGQNWSTISQQALMQNEAIEQVRAICLRAWEKIQDPGSTCPSFNTVRQGSKEPYPDFVARLQDVAQKSDEKARKVIVELMAYENANPECQSAIKPLKGKVPAGSDVISEYVKACDGIGGAMHKAMLMAQAITGVVLGGQVRTFGGKCYNCGQ-KKNCPVLN-ITIQATTTGREPPDLCPRCKK-ASQCRSK................................... 298
51 -10.500sp|P63128|POK4_HUMAN HERV-K_6q14.1 provirus ancestral Gag-Pol polyprotein OS=Homo sapiens PE=3 SV=3  ali   8  4....................................EARYKSFSIKILKDM-------KEGVKQYGPNSPYMRTLLDSIAHGHRLIPYD-----WEILAKSSLSPSQFLQFKTWWIDGVQEQVRRNRAANPPVNIDADQLLGIGQNWSTISQQALMQNEAIEQVRAICLRAWEKIQDPGSTCPSFNTVRQGSKEPYPDFVARLQDVAQKSDEKARKVIVELMAYENANPECQSAIKPLKGKVPAGSDVISEYVKACDGIGGAMHKAMLMAQAITGVVLGGQVRTFGGKCYNCGQ-KKNCPVLN-ITIQATTTGREPPDLCPRCKK-ASQCRSK................................... 298
52 -10.300sp|P14616|INSRR_HUMAN(removed signalp:1-23) Insulin receptor-related protein OS=Homo sapiens GN=INSRR PE=2 SV=2  ali   19  2.....................................................................................................................................................................................ECVCPGVLGAAGEPCAK----TTFSGHTDYRCWTSSHCQRVCPCPHGMACTARGE------------------CCHTECLGGCSQPE----------------DPRACVACGACLWACPPGTYQ---YESWRCVTAERCASLGSCLAQCPSGFTR................................ 137
53 -10.300sp|Q9P0K1|ADA22_HUMAN(removed signalp:1-25) Disintegrin and metalloproteinase domain-containing protein 22 OS=Homo sapiens GN=ADAM22 PE=1 SV=1  ali   24  28............................................................................................................................................................................................................................................................................................DGTPCGPQMMCLERC-LPVASFNFSTCLSSKEGTICSGNGVCSNECNRH................................... 80
54 -10.300sp|P28331|NDUS1_HUMAN NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial OS=Homo sapiens GN=NDUFS1 PE=1 SV=3  ali   12  33..........................................................................................................................................................EVFVDGQSVMVEPGTTVLQACEKVGMQ-CNCRM--------CLVEIEKAPKVVAACAMPVMKGWNILTNSEKSKKAREGVMEFLLANHPLD---------CPICDQGGECDLQDQSMMFGNDRSRFLVKTIMTRCIQCTRCIRFASVDDLGTTGRGNDMQVGT-MSELSGNIIDICPVGALT................................ 232
55 -10.300sp|P06213|INSR_HUMAN(removed signalp:1-27) Insulin receptor OS=Homo sapiens GN=INSR PE=1 SV=4  ali   26  71............................................................................................................................................................................................................................................................................................DPTKCVACGRCVETCPPPYYH---FQDWRCVNFSFCQDLNKCIPECPSGYTM................................ 144
56 -10.300sp|Q9UMN6|MLL4_HUMAN Histone-lysine N-methyltransferase MLL4 OS=Homo sapiens GN=WBP7 PE=1 SV=1  ali   20  53...................................................................................................................................................................................................................................................................................LPSHHGKKMRMARCGHCRGCLRVC------------------GSCVNCGCCVRKCDKIEAR................................ 111
57 -10.200sp|O95405|ZFYV9_HUMAN Zinc finger FYVE domain-containing protein 9 OS=Homo sapiens GN=ZFYVE9 PE=1 SV=2  ali   23  247...........................................................................................................................................................................................................................................................................................VPDSQAPNCMKC--EARFTFTK-----------RHHCRACGFC-ASCCSLKCKLLYMDRKEA....................... 297
58 -10.200sp|P04626|ERBB2_HUMAN(removed signalp:1-22) Receptor tyrosine-protein kinase erbB-2 OS=Homo sapiens GN=ERBB2 PE=1 SV=1  ali   13  5.............................................................................................................................................................................................................................VHTVPWDQLFRNPHQALLHTANRPEDECVGEGLACHQLCARGHCWGPGPTQCVNCSQFLRGQECVEECRVCLPCHPEC-----PQNGSVTCFGPEADQCVACPFCVARCPSGVKP................................ 134
59 -10.200sp|P62685|GAK6_HUMAN HERV-K_8p23.1 provirus ancestral Gag polyprotein OS=Homo sapiens PE=1 SV=2  ali   8  13.......KMLKDMKEGVKQYGPN-----SPYMRTLLDSIAHGHRL--------IPYDWEILAKSSLSPSQFLKTWWIDGVQEQVRRNRAANPPVNIDADQLLGI-WSTISQQALMQNEAIEQVRAICLRAWEKIQDPGSTCPSFNTVRQGSVARLQDVAQKSIADEKARKVIVELMAYENANPECQSAIKPLKGKVPAGSDVISEYVKACDGIGGAMHKAMLMAQAITGVVLGGQVRT----------------------------------------------FGGKCYNCGQ-KKNCPVLN-ITIQATTTGREPPDLCPRCKK-ASQCRSK................................... 298
60 -10.200sp|P63130|GAK12_HUMAN HERV-K_1q22 provirus ancestral Gag polyprotein OS=Homo sapiens PE=3 SV=2  ali   8  13.......KMLKDMKEGVKQYGPN-----SPYMRTLLDSIAHGHRL--------IPYDWEILAKSSLSPSQFLKTWWIDGVQEQVRRNRAANPPVNIDADQLLGI-WSTISQQALMQNEAIEQVRAICLRAWEKIQDPGSTCPSFNTVRQGSVARLQDVAQKSIADEKARKVIVELMAYENANPECQSAIKPLKGKVPAGSDVISEYVKACDGIGGAMHKAMLMAQAITGVVLGGQVRT----------------------------------------------FGGKCYNCGQ-KKNCPVLN-ITIQATTTGREPPDLCPRCKK-ASQCRSK................................... 298
61 -10.200sp|Q99675|CGRF1_HUMAN(removed signalp:1-30) Cell growth regulator with RING finger domain protein 1 OS=Homo sapiens GN=CGRRF1 PE=1 SV=1  ali follow..  19  240............................................................................................................................................................................................................................................................................................NSKDCVVC--CRHTC-------------------LCDGCVKYFQQCPQESFALCSQKEQDKDKPK................... 300
62 -10.100sp|A8MWY0|K132L_HUMAN UPF0577 protein KIAA1324-like OS=Homo sapiens GN=KIAA1324L PE=2 SV=2  ali   21  155...................................................................................................................................................................................................................................................................................RACALGSEQSGSSCVPCNQCKE-CPPDTYL----SIHQVYGKEACIPCGVCYSDCFFYHEK................................ 230
63 -9.990sp|P62684|GAK5_HUMAN HERV-K_19p13.11 provirus ancestral Gag polyprotein OS=Homo sapiens PE=1 SV=2  ali   7  13.......KMLKDMKEGVKQYGPNSPYMRTLLDSIAHGHRLIPYDWEILAKSSLSPDGVQEQVRRNRAANPPVNIDADQLLGIGQNWSTISQQALM-------------NEAIEQVRAICLRAWEKIQDPGSTCPSFNTVRQGSKEPYPDF-VARLQDVAQKSIADEKARKVIVELMAYENANPECQSAIKPLKGKVPAGSDVISEYVKACDGMGGAMHKAMLMAQAITGVVLGGQVRT----------------------------------------------FGGKCYNCGQ-KKNCPVLN-ITIQATTTGREPPDLCPRCKK-ASQCRSK................................... 298
64 -9.960sp|Q6W4X9|MUC6_HUMAN(removed signalp:1-22) Mucin-6 OS=Homo sapiens GN=MUC6 PE=1 SV=2  ali   29  1.........................................................................................................................................................................................................................................................................................SKVYHEACVACG-CDSLC--DAVAA----------AQACLDKGVCPIYCGFYNT................................. 63
65 -9.870sp|A7XYQ1|SOBP_HUMAN Sine oculis-binding protein homolog OS=Homo sapiens GN=SOBP PE=2 SV=2  ali   13  1................................................................................................................................................................................................................................................................................................CAWCQKCSEKC------FAACRRAYFKRNKARDEDGYAKETP-RLAFKNNCELLVCDWCKHIRHTKEYLDFGDGERRLQF 99
66 -9.870sp|Q9HDB9|GAK8_HUMAN HERV-K_3q12.3 provirus ancestral Gag polyprotein OS=Homo sapiens GN=ERVK5 PE=1 SV=3  ali   9  13.......KMLKDIKEGVKQYGSN-----SPYIRTLLDSIATPYDWESLAKSSLSSDGVQEQVRKNQATKPTVNIDADQLLGTGPNWSTINQQSVMQNEAIEQVRAICLRAWGKIQDPGTAFPINSIRQG--KEPYPDFVARLQDAAQKSITDDNARKVIVELMAYENANP-------------ECQSAIKPLKGKVPAGVDVITEYVKACDGIGGAMHKAMLMAQAMRGLTLGGQVRT----------------------------------------------FGKKCYNCGQ-KRSCPVLN-INQAITAKNKKPSGLCPKCKHWANQCHSK................................... 298
67 -9.810sp|Q9UBW7|ZMYM2_HUMAN Zinc finger MYM-type protein 2 OS=Homo sapiens GN=ZMYM2 PE=1 SV=1  ali   18  180...............................................................................................................................................................................................................................................................................................TCANCKKCSTTC--------SSFSHKPAPKKLCVMCKKCSTSC...................................... 255
68 -9.810sp|Q9C0F0|ASXL3_HUMAN Putative Polycomb group protein ASXL3 OS=Homo sapiens GN=ASXL3 PE=2 SV=3  ali   35  260.............................................................................................................................................................................................................................................................................................ELKC--------SCRLKAMIV-------------CKGCGACHDDCPSKCVALVVR............................ 298
69 -9.790sp|Q14767|LTBP2_HUMAN(removed signalp:1-35) Latent-transforming growth factor beta-binding protein 2 OS=Homo sapiens GN=LTBP2 PE=1 SV=3  ali   16  124............................................................................................................................................................................................................................................................................................PRGRLTGRNVCGGQCCPG---WTTANSTNHCIKPVC-PCGSCSRVCRSG................................... 177
70 -9.790sp|P21860|ERBB3_HUMAN(removed signalp:1-19) Receptor tyrosine-protein kinase erbB-3 OS=Homo sapiens GN=ERBB3 PE=1 SV=1  ali   20  250............................................................................................................................................................................................................................................................................................GSDTCAQCPHCVSSCPHGVLGAKGPIYKYPDVQNECR---PCHENCTQ.................................... 300
71 -9.780sp|Q9BV36|MELPH_HUMAN Melanophilin OS=Homo sapiens GN=MLPH PE=1 SV=1  ali follow..  14  8...........................................................................................................................................................................................................................SKLTDEEAQHVLEVVQRDFDLRRKEEER--------------LKGKIKKESSKRELLSDT--AHLNETHCARCLQCLE-CGLFT----------------CKSCGIC-DPCHLAR.................................. 111
72 -9.780sp|Q76L83|ASXL2_HUMAN Putative Polycomb group protein ASXL2 OS=Homo sapiens GN=ASXL2 PE=1 SV=1  ali   38  197.............................................................................................................................................................................................................................................................................................PSKC--------YCRLKAMIM-------------CKGCGACHDDC-IGPSKL............................... 227
73 -9.710sp|Q9Y2I7|FYV1_HUMAN 1-phosphatidylinositol-3-phosphate 5-kinase OS=Homo sapiens GN=PIKFYVE PE=1 SV=3  ali   22  156...........................................................................................................................................................................................................................................................................................MPDSQCKECYDCSE--KFTTFR----------RRHHCRLCGFC-SRCCNQEIPGK.............................. 199
74 -9.700sp|Q86XX4|FRAS1_HUMAN(removed signalp:1-26) Extracellular matrix protein FRAS1 OS=Homo sapiens GN=FRAS1 PE=2 SV=1  ali   12  8..............................................................................................................................................................................FGECQYESCAPQYYLDFSTNTCKECDWSCSASGPLKTDCLQCMDGYVLQDGACVEQCLSSF-------------QDSGLCKCDSYCLQCQ--------------------GPHECTRCAQCVQECGKGYFADHAKHKLQCSHRDRCHLCGLCVYNCVPG................................... 159
75 -9.700sp|Q15650|TRIP4_HUMAN Activating signal cointegrator 1 OS=Homo sapiens GN=TRIP4 PE=1 SV=4  ali follow..  12  1MGAVSGEPLVHWCTQQLRKT---FGLDVSEEIIQYVLSIESAEEIR------------EYVTDLLQGNEGKKGQFIEELITKWQKNDQELISDPLQQCFKKDEILDGQKSGDHLKRGRKKGRNRQEVPAFTEPDTTAEVKTPFDLAKAQENSNSVKKKTKFVNLYTREGQDRLAVLLPGRHPCDC-----------------------------------------------LGQKHKLI----------------------------------------------NNCLICGRIV--CEQE-------------------GSGPCL--CGTLVCTHEEQDILQRDSNKSQKLLKKLMSGVENS.... 237
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Li W, Godzik A. cd-hit: a fast program for clustering and comparing large sets of protein or nucleotide sequences. Bioinformatics. 2006 May 26;