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Query: [S] COG2149 Predicted membrane protein, from COG1018

Results of FFAS03 search in H.sapiens
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
    .   10    .   20    .   30    .   40    .   50    .   60    .   70    .   80    .   90    .  100    .  110    .
# Score Template Links and tools%idFirst MKISRLGEAPDYRFSLANERTFLAWIRTSLGFLAAGVGLDQLAPDFATPVIRELLALLLCLFAGGLAIYGYLRWLRNEKAMRLKEDLPYTHSLLIISVILMIVAVIVMGLVLYAGLast
1 -24.500sp|Q9NX00|TM160_HUMAN(removed signalp:1-22) Transmembrane protein 160 OS=Homo sapiens GN=TMEM160 PE=2 SV=1  ali follow..  22  42..............RKAHETAFLSWFRNGLLASGIGVIS------FMQSDMGREAAYGFFLLGGLCVVWGSASYAVGLAALRGPMQLTLGGAAVGAGAVLAASLLWACAVGLYMG 136
2 -10.500sp|Q9UF02|CCG5_HUMAN(removed signalp:1-29) Voltage-dependent calcium channel gamma-5 subunit OS=Homo sapiens GN=CACNG5 PE=2 SV=2  ali follow..  14  55.....QLTSESTVNVLKMIRSATPFPLVSLFFMFIGFILNNIGHIRPHRTILAFVSGIFFILSGLSLVVGLVLYISSINDEMLNRTKDAETYFNYKYGWSFAFAAISFLLTESAG 164
3 -10.300sp|P11836|CD20_HUMAN B-lymphocyte antigen CD20 OS=Homo sapiens GN=MS4A1 PE=1 SV=1  ali follow..  12  42............QSFFMRESKTLGAVQIMNGLFHIALGGLLMIPAGIYAPICVTVWYPLWG-GIMYIISGSL-------LAATEKNSRKCLVKGKMIMNSLSLFAAISGMILSI. 135
4 -10.000sp|Q9NV92|NFIP2_HUMAN NEDD4 family-interacting protein 2 OS=Homo sapiens GN=NDFIP2 PE=1 SV=2  ali follow..  11  227...............VGNDGIFMLAFFMAFIFNWLGFCLSFCITNTIAGRYGAICGFIFLVLGLLLFFRGFVNYLKVRNMSESMAAAHRTRYFFLL................... 336
5 -9.930sp|Q9BT67|NFIP1_HUMAN(removed signalp:1-16) NEDD4 family-interacting protein 1 OS=Homo sapiens GN=NDFIP1 PE=1 SV=1  ali follow..  15  96...............IGNDGIFMLTFFMAFLFNWIGFFLSFCLTTSAAGRYGAISGFVFLVLGFLLFLRGFINYAKVRKMPETFSNLPRTR........................ 200
6 -9.680sp|Q9H6X4|TM134_HUMAN Transmembrane protein 134 OS=Homo sapiens GN=TMEM134 PE=2 SV=1  ali follow..  17  119................KNRRVVLA----SFLLLLLGLVLILVGVGLEATPSPGVSSAIFFVPGFLLLVPGVYHVIFIYCAVK................................. 180
7 -9.610sp|Q8NBL3|TM178_HUMAN(removed signalp:1-25) Transmembrane protein 178 OS=Homo sapiens GN=TMEM178 PE=2 SV=1  ali follow..  12  136.....KTIQQDEWHLLHLRRITAGFLGMAVAVLLCGCIVATVSFFWEESLTQHVAGLLFLMTGIFCTIS-YAASISYDLNRLPKLIYSLPADVEHGYSWSIFCAWCSLGFIVAAG 247
8 -9.520sp|P62955|CCG7_HUMAN(removed signalp:1-20) Voltage-dependent calcium channel gamma-7 subunit OS=Homo sapiens GN=CACNG7 PE=1 SV=1  ali follow..  11  78...................RTATPFPMVSLFLVFTAFVISNIGHIRPQRTILAFVSGIFFILSGLSLVVGLVLYISSINDEVMNRPSSSEQYFHYRYGWSFAFAASSFLLKEGAG 173
9 -9.330sp|Q9UGI6|KCNN3_HUMAN Small conductance calcium-activated potassium channel protein 3 OS=Homo sapiens GN=KCNN3 PE=2 SV=1  ali   14  128............RRALFEKRKRLSDYALIFGMFGIVVMVIEWGLYSKDSMFSLALKCLISLSTIILLGLIIAYHTREVQLFVIDNGADDWRIAMTYERILYISLEMLVCAI.... 230
10 -9.250sp|Q06432|CCG1_HUMAN(removed signalp:1-23) Voltage-dependent calcium channel gamma-1 subunit OS=Homo sapiens GN=CACNG1 PE=2 SV=1  ali follow..  10  81..................SISAAAIAIFSLGFIILGSLCVLLSLGKKRDYLLRPASMFYAFAGLCILVSVEVMRQSVKRMIDSEDTVWIEYYYS-----SFACACAAFILLFLGG 173
11 -9.150sp|Q8WXS5|CCG8_HUMAN Voltage-dependent calcium channel gamma-8 subunit OS=Homo sapiens GN=CACNG8 PE=2 SV=3  ali follow..  13  126...................RASSIFPILSAILLLLGGVCVAASRVYKSKRNIILGAGILFVAAGLSNIIGVIVYISANAGEPGPKRDEEKKNHYSYG--SFYFGGLSFILAEVIG 220
12 -9.140sp|Q08462|ADCY2_HUMAN Adenylate cyclase type 2 OS=Homo sapiens GN=ADCY2 PE=1 SV=5  ali   10  129ISLLFYNKVLEKEYRATALPAFKYYVTCAC-LIFFCIFIVQILVLPKTSVLGISFGAAFLLLAFILFVCFAGQLLQCSKKASPSGIIANRPWPRISLTIITTAIILMMAVF.... 246
13 -9.020sp|Q96Q45|AL2S4_HUMAN Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 4 protein OS=Homo sapiens GN=ALS2CR4 PE=1 SV=1  ali follow..  14  233.....KPSWTTRDVALTVHRAFRMIGLFSHGFLA-GCAVWNIV-LQQYKTLAYPFQSLLYLLLALSTISAFDRIDFAKISVAIRNFLALDPTALASFLYFTALILSLSQQMT... 353
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Pawlowski K, Pio F, Chu Z, Reed JC, Godzik A. PAAD - a new protein domain associated with apoptosis, cancer and autoimmune diseases. Trends Biochem Sci. 2001 Feb;26(2):85-7.