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Query: [S] COG2510 Predicted membrane protein, from COG1018

Results of FFAS03 search in H.sapiens
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MMMASWQFWALMSAVFAALTAIFAKVGIQGINSDFATLVRTFVIIGALCLFLTVTGQWQKPGEISARSWLFLVLSGLATGASWLAYFRALQIGDASRVAPIDKLSVVLVALFGAAFLGERMSTINWIGILLIGCGVVLVALRVLast
1 -47.100sp|Q2M3R5|TMM20_HUMAN Transmembrane protein 20 OS=Homo sapiens GN=TMEM20 PE=2 SV=1  ali follow..  18  70....LGLFYTLLSAFLFSVGSLFVKK-VQDVHAVEISAFRCVFQMLVVIPCLIYRKTG---FIGPKGQRIFLILRGVLGSTAMMLIYYAYQTMSLADATVITFSSPVFTSIFAWICLKEKYSPWDALFTVFTITGVILIVRP. 203
2 -43.700sp|Q8TBE7|TMM22_HUMAN Transmembrane protein 22 OS=Homo sapiens GN=TMEM22 PE=1 SV=3  ali follow..  13  100.QSRKMWIVLFGSALAHGCVALITRLVSDKVPSLELIFIRSVFQVLSVLVVCYYQE----APFGPSGYRLRLFFYGVCNVISITCAYTSFSIVPPSNGTTMRATTTVFSAILAFLLVDEKMAYVDMATVVCSILGVCLVMIPN 240
3 -41.900sp|P0C7Q6|AMCL3_HUMAN Protein AMAC1L3 OS=Homo sapiens GN=AMAC1L3 PE=2 SV=1  ali follow..  14  38....NGLLVALLGGGLPAGFVGPLSHMASNLPSLELLICRCLFHLPIALLLKLRGDP----LLGPPDIRGRAYFYALLNVLSIGCAYSAVQVVPAGNAATVKGSSTVCSAVLTLCLESQGLSGYDWCGLLGSILGLIIIVGP. 175
4 -41.800sp|Q96KT7|AMCL2_HUMAN Protein AMAC1L2 OS=Homo sapiens GN=AMAC1L2 PE=2 SV=1  ali follow..  13  37...TNGLLVALLGGGLPAGFVGPLSRMAYNLPSLELLICRCLFHLPIALLLKLRGDP----LLGPPDIRGWACFCALLNVLSIGCAYSAVQVVPAGNAATVKGSSTVCSAVLTLCLESQGLGGYEWCGLLGSILGLIIILGP. 175
5 -41.000sp|Q8N808|AMAC1_HUMAN Protein AMAC1 OS=Homo sapiens GN=AMAC1 PE=2 SV=1  ali follow..  14  35.DATSGLLVALLGGGLPAGFVGPLSRMASNLPSLELLIWRCLFHLPIALLLKLRGDP----LLGTPDIRSRAFFCALLNILSIGCAYSAVQVVPAGNAATVKGSSTVCSAVLTLCLESQGLSGYDWCGLLGCILGLIIIVGP. 175
6 -40.500sp|P0C7Q5|AMCL1_HUMAN Protein AMAC1L1 OS=Homo sapiens GN=AMAC1L1 PE=4 SV=1  ali follow..  11  42.....VALLGGGLPAGFVGPLSRMAYQASNLPSLELVICRCLFHLPIALLLKLRGDP----LLGPPDIRGRTCFCALLNVLNIGCAYSAVQVVPTGNAATVKHSSTVCSAILTLCLESQVLSGYDWCGLLGSILGLIIIVGPG 176
7 -33.200sp|Q5T1Q4|S35F1_HUMAN Solute carrier family 35 member F1 OS=Homo sapiens GN=SLC35F1 PE=2 SV=2  ali follow..  15  64......VALGQVLSLLICGIGLTSKYLSEDFHPVFQSFLNYILLFLVYTTTLAVRQGEENLLAILRRRWWKYMILGLIDLEANYLVVKAYQYTTLTSIQLLDCFVIPVVILLSWFFLLIRYKAVHFIGIVVCILGMGCMVGA. 202
8 -32.200sp|Q8WV83|S35F5_HUMAN Solute carrier family 35 member F5 OS=Homo sapiens GN=SLC35F5 PE=2 SV=1  ali follow..  14  329.....GSIWSLAGAMLYAVYIVMIKRKVDREDKLDIPMFFGFVGLFNLLLLLLHYTGFEDFEFPNKVVLMCIIINGLITVLSEFLWLWGCFLTSSLIGTLALSLTIPLSIIADMCMQKVQFSWLFFAGAIPVFFSFFIVTLL. 471
9 -31.900sp|Q8IXU6|S35F2_HUMAN Solute carrier family 35 member F2 OS=Homo sapiens GN=SLC35F2 PE=1 SV=1  ali follow..  9  198.....GDILVLLGASLYAISNVCEEYIVKKLSRQEFLGMVGLFGTIISGIQLLIVEYKDIASIHWDWKIALLFVAFALMFCLYSFMPLVIKVTSATSVNLGILTADLYSLFVGLFLFGYKFSGLYILSFTVIMVGFILYCST. 335
10 -31.300sp|A4IF30|S35F4_HUMAN Solute carrier family 35 member F4 OS=Homo sapiens GN=SLC35F4 PE=2 SV=2  ali follow..  12  167.....GLLIILSVSSSWVGTTQIVKITYKNFYCPFFMTWFSTNWNIMFFPVYYSSRIFGEDGLTLKLFLKRTAPFSILWTLTNYLYLLALKKLTATDVSALFCCNKAFVFLLSWIVLKDRFMGVRIVAAIMAITGIVMMAYA. 322
11 -30.900sp|Q8IY50|S35F3_HUMAN Solute carrier family 35 member F3 OS=Homo sapiens GN=SLC35F3 PE=2 SV=2  ali follow..  13  69.....GVAVVLCVCSSWAGSTQLAKLTFRKFDPFTLTWFATNWNFLFFPLYYVGHVCKSTEKQSVKVFFTKAAPFGVLWTLTNYLYLHAIKKINTTDVSVLFCCNKAFVFLLSWIVLRDRFMGVRIVAAILAIAGIVMMTY.. 223
12 -30.100sp|Q69YG0|TMM42_HUMAN Transmembrane protein 42 OS=Homo sapiens GN=TMEM42 PE=2 SV=2  ali follow..  23  39.....GVFNCLCAGAFGALAAASAKLAFGSEVSMGLCVL-------------------------------GIIVMASTNSLMWTFFSRGLSFSMSSAIASVTVTFSLSSAFLGYVLYGECQEVLWWGGVFLILCGLTLIHRK. 146
13 -26.000sp|Q96K37|S35E1_HUMAN Solute carrier family 35 member E1 OS=Homo sapiens GN=SLC35E1 PE=1 SV=2  ali follow..  15  190.....GLVSALAATLCFSLQNIFSKKVLRRIHHLRLLNILGCHAVFFMIPTWVLVDLSAFLVS-WPWTLLLLAVSGFCNFAQNVIAFSILNLVSPLSYSVANATKRIMVITVSLIMLRNPVTSTNVLGMMTAILGVFL..... 331
14 -25.800sp|Q96A29|FUCT1_HUMAN GDP-fucose transporter 1 OS=Homo sapiens GN=SLC35C1 PE=1 SV=1  ali follow..  13  198.....GTVFGVLASLCVSLNAIYTTKVLPDGSIWRLTFYNNVNACILFLPLLLLLGELQALRDFSAHFWGMMTLGGLFGFAIGYVTGLQIKFTSPLTHNVSGTAKACAQTVLAVLYYEETKSFLWWTSNMMVLGGSSAYT... 338
15 -25.200sp|Q6ICL7|S35E4_HUMAN Solute carrier family 35 member E4 OS=Homo sapiens GN=SLC35E4 PE=2 SV=1  ali follow..  21  188.....GCGFLLAATCLRGLKSVQQSALLQRLDAVTLLYATSLPSFCLLAGAALVLEAGVAPPP-DSRLWACILLSCLLSVLYNLASFSLLALTSALTVHVLGNLTVVGNLILSRLLFGSRLSALSYVGIALTLSGMFL..... 324
16 -25.100sp|Q9H1N7|S35B3_HUMAN Adenosine 3`-phospho 5`-phosphosulfate transporter 2 OS=Homo sapiens GN=SLC35B3 PE=1 SV=1  ali follow..  12  228.....GVVLISLALCADAVIGNVQEKAMKNASNSEMVLYSYSIGFVYILLGLTCTSGLGPAVTFPVRTYGYAFLFSLTGYFGISFVLALIKIFGALIAVTVTTGRKAMTIVLSFIFFAKPFTFQYVWSGLLVVLGIFL..... 366
17 -24.900sp|Q5CZA4|S35E2_HUMAN Solute carrier family 35 member E2 OS=Homo sapiens GN=SLC35E2 PE=2 SV=2  ali follow..  13  224.....GFSAALSTNIMDCLQNVFSKKLLSGFSAPELQFYTSAAAVAMLVPARVFFTDVPVIGRYNQDVVLLLLTDGVLFHLQSVTAYALMGKISPVTFSVASTVKHALSIWLSVIVFGNKITSLSAVGTALVTVGVLLYNK.. 369
18 -24.900sp|Q8WY98|CA091_HUMAN(removed signalp:1-23) UPF0546 membrane protein C1orf91 OS=Homo sapiens GN=C1orf91 PE=2 SV=1  ali follow..  19  34.......................................................................YLMPFLLNQCGSLLYYLTLASTDLTLAVPINSLAIIFTLIVGKALGEDIGGKRAVAGMVLTVIGISLCITSS 106
19 -24.400sp|Q9NQQ7|S35C2_HUMAN(removed signalp:1-28) Solute carrier family 35 member C2 OS=Homo sapiens GN=SLC35C2 PE=1 SV=2  ali follow..  16  137.....GFALVLGASFIGGIRWTLTQMLLQKQNPIDTMFHLQPLMFLGLFPLFAVFEGLHLSTSLLLRVLGSLFLGGILAFGLGFSEFLLVSRTSSLTLSIAGIFKEVCTLLLAAHLLGDQISLLNWLGFALCLSGISL..... 284
20 -23.400sp|Q7Z769|S35E3_HUMAN Solute carrier family 35 member E3 OS=Homo sapiens GN=SLC35E3 PE=2 SV=1  ali follow..  14  155.....GMVFAALGVLVTSLYQVWVGAKQHQVNSMQLLYYQAPMSSAMLLVAVPFFEPVFGEGGISVSALLMVLLSGVIAFMVNLSIYWIIGNTSPVTYNMFGHFKFCITLFGGYVLFKDPLSINQALGILCTLFGILAYT... 295
21 -23.200sp|Q5M8T2|S35D3_HUMAN(removed signalp:1-19) Solute carrier family 35 member D3 OS=Homo sapiens GN=SLC35D3 PE=2 SV=1  ali follow..  8  138.....GYVTGVLAVLVHAAYLVLIQKASAEHGPLTAQYVIAVSATPLLVICSFASTDSIHAWTFDPAMVCIFVACILIGCAMNFTTLHCTYINSAVTTSFVGVVKSIATITVGMVAFSDEPTSLFIAGVVVNTLGSIIYCV.. 280
22 -22.200sp|Q8N357|CB018_HUMAN(removed signalp:1-18) Transmembrane protein C2orf18 OS=Homo sapiens GN=C2orf18 PE=1 SV=1  ali follow..  21  29................................PFLQAVGMFLGEFSCLAAFYLLGQSDSSVDPQQPFNPLLFLPPALCDMTGTSLMYVALNMTSASSFQMLRGAVIIFTGLFSVAFLGRRLVLSQWLGILATIAGLVVVGL.. 142
23 -22.100sp|Q9NTN3|S35D1_HUMAN UDP-glucuronic acid/UDP-N-acetylgalactosamine transporter OS=Homo sapiens GN=SLC35D1 PE=1 SV=1  ali follow..  17  187.....GYAFILINDVLTAANGAYVKQKLDELGKYGLLYYNALFMILPTLAIAYFTGDAQKAVEFDTLFLLQFTLSCVMGFILMYATVLCTQYNSALTTTIVGCIKNILITYIGMVFGGDYFTWTNFIGLNISIAGSLVYS... 328
24 -22.000sp|Q7RTP0|NIPA1_HUMAN Magnesium transporter NIPA1 OS=Homo sapiens GN=NIPA1 PE=1 SV=1  ali follow..  18  31.....GLGVAVVSSLVNGSTFVLQKKGIVRAKRRGTSYLTDIVWWAGTIAMA----------------------------VGQIGNFLAYTAVPTVLVTPLGALGVPFGSILASYLLKEKLNILGKLGCLLSCAGSVVLII.. 138
25 -21.900sp|P78383|S35B1_HUMAN Solute carrier family 35 member B1 OS=Homo sapiens GN=SLC35B1 PE=2 SV=1  ali follow..  16  172.....GELLLLLSLTLDGLTGVSQDHMRAHTGSNHMMLNINLWSTLLLGMGILFTGELWEFLSFAERYIYNILLFGLTSALGQSFIFMTVVYFGPLTCSIITTTRKFFTILASVILFANPISPMQWVGTVLVFLGLGL..... 309
26 -21.900sp|Q24JQ0|CR045_HUMAN(removed signalp:1-18) Transmembrane protein C18orf45 OS=Homo sapiens GN=C18orf45 PE=2 SV=1  ali follow..  12  132.....GYFWAIIHLLCVGAYKILQKSQKPALSDIDQQYLNYIFSVVLLAFASHPTGDLFSVLDFFYRFHGSCCASGFLGFFLMFSTVKLKNLLAPGQCAAWIFFAKIITAGLSILLFDAILTSATTGCLLLGALGEALLVF.. 272
27 -21.800sp|Q76EJ3|S35D2_HUMAN UDP-N-acetylglucosamine/UDP-glucose/GDP-mannose transporter OS=Homo sapiens GN=SLC35D2 PE=1 SV=1  ali follow..  16  172.....GYIFVFLNDIFTAANGVYTKQKMDELGKYGVLFYNACFMIIPTLIISVSTGDLQQATEFNVVFILQFLLSCFLGFLLMYSTVLCSYYNSALTTAVVGAIKNVSVAYIGILIGGDYFSLLNFVGLNICMAGGLRYS... 313
28 -21.300sp|Q969S0|S35B4_HUMAN(removed signalp:1-16) UDP-xylose and UDP-N-acetylglucosamine transporter OS=Homo sapiens GN=SLC35B4 PE=2 SV=1  ali follow..  12  147.....GIGALTFALLMSARMGIFQETLYKGKHSKEALFYNHALPLPGFVFLASD--EIPVIGVTLPIMWFYLLMNIITQYVCIRGVFILTTECASLTVTLVVTLRKFVSLIFSILYFQNPFTLWHWLGTLFVFIGTLM..... 293
29 -21.200sp|Q6NVV3|NIPA3_HUMAN Magnesium transporter NIPA3 OS=Homo sapiens GN=NIPAL1 PE=2 SV=1  ali follow..  25  71.....GLVLAVSSSIFIGSSFILKKKGLLQLAS---------------------GFTRAGQGGHSYLKEWLWWVGLLSMGAGEAANFAAYAFAPATLVTPLGALSVLISAILSSYFLNEHLNIHGKIGCILSILGSTVMVI.. 186
30 -21.100sp|Q8N8Q9|NIPA2_HUMAN Magnesium transporter NIPA2 OS=Homo sapiens GN=NIPA2 PE=2 SV=1  ali follow..  25  13.....GLGLAMSSSIFIGGSFILKKKGLLRLAR--------------------KGSMRAGQGGHAYLKEWLWWAGLLSMGAGEVANFAAYAFAPATLVTPLGALSVLVSAILSSYFLNERLNLHGKIGCLLSILGSTVMVI.. 128
31 -19.800sp|Q9H841|NPAL2_HUMAN NIPA-like protein 2 OS=Homo sapiens GN=NIPAL2 PE=2 SV=1  ali follow..  15  50.....GVLLAILGNLVISISLNIQKYSHLQLAQ-PRPYFKSVLWWGGVLLMA----------------------------VGETGNFAAYGFAPITLIAPLGCVSVTGSAIISVTFLKDNLRASDLLGTTLAFAGTYLLVN.. 159
32 -19.700sp|Q8TB61|S35B2_HUMAN(removed signalp:1-20) Adenosine 3`-phospho 5`-phosphosulfate transporter 1 OS=Homo sapiens GN=SLC35B2 PE=1 SV=1  ali follow..  12  251.....GLILLAGYIAFDSFTSNWQDALFAY-SSVQMMFGVNFFSCLFTVGSLLEQGALLEGTRFMGRHAAHALLLSICSACGQLFIFYTIGQFGAAVFTIIMTLRQAFAILLSCLLYGHTVTVVGGLGVAVVFAALLL..... 387
33 -19.600sp|Q0D2K0|NIPA4_HUMAN Magnesium transporter NIPA4 OS=Homo sapiens GN=NIPAL4 PE=1 SV=3  ali follow..  19  121.....GLGLAFLSSFLIGSSVILKKKGLLRLVA---------------------GATRAVDGGFGYLKDAMWWAGFLTMAAGEVANFGAYAFAPATVVTPLGALSVLISAILSSYFLRESLNLLGKLGCVICVAGSTVMVI.. 236
34 -19.200sp|Q96G79|S35A4_HUMAN(removed signalp:1-31) Probable UDP-sugar transporter protein SLC35A4 OS=Homo sapiens GN=SLC35A4 PE=2 SV=1  ali follow..  19  16.............................PFRPSSAVLLTELTKLLLCAFSLLVGWQAWPQGPPPWRQAAPFALSALLYGANNNLVIYLQRYMDPSTYQVLSNLKIGSTAVLYCLCLRHRLSVRQGLALLLLMAAGACYAAGG 129
35 -19.200sp|P78381|S35A2_HUMAN UDP-galactose translocator OS=Homo sapiens GN=SLC35A2 PE=1 SV=1  ali follow..  16  37......YISLAVLVVQNASLILSIRYARTRFFATTAVVMAEVLKGLTCLLLLFAQKRGNVKHLVQYVDTLKLAVPSLIYTLQNNLQYVAISNLPAATFQVTYQLKILTTALFSVLMLNRSLSRLQWASLLLLFTGVAIVQAQQ 186
36 -18.600sp|Q9BS91|S35A5_HUMAN(removed signalp:1-32) Probable UDP-sugar transporter protein SLC35A5 OS=Homo sapiens GN=SLC35A5 PE=1 SV=2  ali follow..  12  16.............................DYLPTTVNVCSELVKLVFCVLVSFCVIKKDHQSR-EFSDFMKWSIPAFLYFLDNLIVFYVLSYLQPAMAVIFSNFSIITTALLFRIVLKRRLNWIQWASLLTLFLSIVALTAGT 136
37 -17.600sp|P78382|S35A1_HUMAN(removed signalp:1-24) CMP-sialic acid transporter OS=Homo sapiens GN=SLC35A1 PE=2 SV=1  ali follow..  19  1.................AVYTIALRYTRTSYFSTTAVCITEVIKLLLSVGILAKETGSLGRFK-SPKELLKLSVPSLVYAVQNNMAFLALSNLDAAVYQVTYQLKIPCTALCTVLMLNRTLSKLQWVSVFMLCAGVTLVQWK. 137
38 -16.700sp|Q6P499|NPAL3_HUMAN NIPA-like protein 3 OS=Homo sapiens GN=NIPAL3 PE=1 SV=1  ali follow..  17  36.....GALLAIFGHLVVSIALNLQKYCHLAGSKDPRAYFKTKTWWLGLFLML----------------------------LGELGVFASYAFAPLSLIVPLSAVSVIASAIIGIIFIKEKWKPKDFVGCGLAVVGTYLLVTFA 155
39 -16.500sp|Q8TAD4|ZNT5_HUMAN Zinc transporter 5 OS=Homo sapiens GN=SLC30A5 PE=1 SV=1  ali   11  33......IVLLCFTKFLKAVGLFESYDLLKAVHIVQFIFILKLGTAFFMVLF---QKPFSSGKTITKHQWIKIFKHAVAGCIISLLWFFGLTLCPLRTLLLFEHSDIVVISLLSVLFTSSGGGPAKTRGAAFFIIAVICLLL.. 165
40 -15.700sp|Q9Y2D2|S35A3_HUMAN(removed signalp:1-19) UDP-N-acetylglucosamine transporter OS=Homo sapiens GN=SLC35A3 PE=2 SV=1  ali follow..  18  17.............................RYLSSTAVVVAELLKIMACILLVYKDSKCSLRALNRVMETLKLAIPSGIYTLQNNLLYVALSNLDAATYQVTYQLKILTTALFSVSMLSKKLGVYQWLSLVILMTGVAFVQWPS 139
41 -14.700sp|Q7Z5S9|TM144_HUMAN Transmembrane protein 144 OS=Homo sapiens GN=TMEM144 PE=2 SV=1  ali follow..  16  189.....GCSLAVISGVLYGSTFVPIIYIKDHSKRNDVFAHFSGIFLTSTVYFLAYCIAMKNSPKLYPEAVLPGFLSGVLWAIATCCWFIANHSLSAVVSFPIITAGPFIAAMWGIFMFKEIKGLQNYLAFCIILTGALCTAFS. 343
42 -11.900sp|Q96Q45|AL2S4_HUMAN Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 4 protein OS=Homo sapiens GN=ALS2CR4 PE=1 SV=1  ali follow..  14  259FLAGCAVWNIVVIYVLAGDQLSNLSNLLQQYKTLAYPFQSLLYLLLALSTISAFDRIDFAKISVAIRNFLALDPTALASFLYFTALILSLSQQMTSDRIHLYTPSSVNGSLWEAGIEEQILQPWIVVNLLLVGLSWLFLSYRP 404
43 -9.800sp|Q8TBB6|S7A14_HUMAN Probable cationic amino acid transporter OS=Homo sapiens GN=SLC7A14 PE=2 SV=3  ali   7  1......................................................................VVLMVLLISTLVFVILQQPENPKKLPYMAPCLPFVPAFAMLVNIYLMLKLSTITWIRFAVWCFVGLLIYFG.. 71
44 -9.620sp|O14514|BAI1_HUMAN(removed signalp:1-30) Brain-specific angiogenesis inhibitor 1 OS=Homo sapiens GN=BAI1 PE=1 SV=1  ali   13  5LSLEGGLLYAFVGPAAAVVL-------------VNMVIGILVFNKLVSKDGITDKKLKERAGASLWSSCVVLPLLALTWMSAVLAVTDRRSALFQILFAVFDSLEGFVIVMVHCILRRE........................ 110
45 -9.140sp|Q9BSE2|TMM79_HUMAN Transmembrane protein 79 OS=Homo sapiens GN=TMEM79 PE=1 SV=1  ali follow..  11  241....RCGVFATFPIVLGILVYGLSLLCFSALRPFEVEIHRRYVAQSVQLFILYFFNLAVLSTYLPQDTLKLLPLLTGLFAVSRLIYWLTFAVGRSFRGFGYGLTFPLLSMLMWNLYYMFVVEPERMLTAT............. 372
46 -9.040sp|O43306|ADCY6_HUMAN Adenylate cyclase type 6 OS=Homo sapiens GN=ADCY6 PE=1 SV=2  ali   12  147.MNQSSLTLLMAVLVLLTAVLLAFHAAPARPQPAYVALLACAAALFVGLMVVCNRHSF-------RQDSMWVVSYVVLGILAAVQVGGALAADPRSPSAGLWCP--VFFVYIAYTLLPIRMRAAVLSGLGLSTLHLILAWQLN 279
FFAS is supported by the NIH grant R01-GM087218-01
1 4 8 3 1 9   jobs submitted since Jan 1, 2011
Comments and questions to: webmaster
Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Ye Y, Godzik A. Multiple flexible structure alignment using partial order graphs. Bioinformatics. 2005 Mar 3;