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Query: [S] COG4244 Predicted membrane protein, from COG1018

Results of FFAS03 search in H.sapiens
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MFTLNDQNLPYPDTLHPIIVHFVIGMVFFAYISELVGYLQKKPRFFEVAWWNWLTAAIAIFFAVIFGEFEAALAMPYPAAQPALDWHTVNGWSLSAILAGLTAWRGVLRVRNPLKTSLPFLMLATVFMVLVCIQIFLGSLVDWVYGLHTLPVVQATKDGIIPLast
1 -14.700sp|Q8NBI2|CYAC3_HUMAN(removed signalp:1-36) Cytochrome b ascorbate-dependent protein 3 OS=Homo sapiens GN=CYBASC3 PE=1 SV=1  ali follow..  8  9.............NWHPVLMVAGMVVFYGGASL-VYRLPQSWVGPKLPWKLLHAALHLMAFVLTVVGLVAVFTFHNHGRTANLYSLHSWLGITTVFLFACQWFLGFAVSMWLRSLLKPIHVFFGAAILSLSIASVISG........................ 138
2 -14.000sp|P49447|CY561_HUMAN(removed signalp:1-33) Cytochrome b561 OS=Homo sapiens GN=CYB561 PE=2 SV=2  ali follow..  8  18.............NAHPLCMVIGLIFLQGNALLVYRVFRNEAKRTTKVLHGLL----IFALVIALVGLVAVFDYHRKKGYADLYSLHSWCGILVFVLYFVQWLVGFSFSFSLRSRYRPQHIFFGATIFLLSVGTALLG........................ 145
3 -13.700sp|O14569|C56D2_HUMAN Cytochrome b561 domain-containing protein 2 OS=Homo sapiens GN=CYB561D2 PE=1 SV=1  ali follow..  10  46.............SWHPVLMSLAFSFLMTEALLVFSPESSLLHSLSRKGRARCHWVLLLALLCALLGLGLVILHKEQLGKAHLVTRHGQAGLLAVLWAGLGLLYPKLLPRWPLAKLKLYHATSGLVGYLLGSASLLLG........................ 177
4 -13.600sp|Q8N8Q1|C56D1_HUMAN Cytochrome b561 domain-containing protein 1 OS=Homo sapiens GN=CYB561D1 PE=2 SV=1  ali follow..  12  53.............SWHPVFMALAFCLCMAEAILLFSPEHSLFFFCSRKARIRLWAGQTLAILCAALGLGFIISSRTRSELPHLVSWHSWVGALTLLATAVCLLCPRAARVSRVARLKLYHLTCGLVVYLMATVTVLLG........................ 184
5 -13.400sp|Q53TN4|CYBR1_HUMAN(removed signalp:1-27) Cytochrome b reductase 1 OS=Homo sapiens GN=CYBRD1 PE=1 SV=1  ali follow..  7  21.............NWHPVLMVTGFVFIQGIAII-VYRLPWTWKCSKLLMKSIHAGLNAVAAILAIISVVAVFENHNVNNIANMYSLHSWVGLIAVICYLLQLLSGFSVPLSLRAFLMPIHVYSGIVIFGTVIATALMG........................ 150
6 -10.600sp|Q8TEB9|RHBD1_HUMAN Rhomboid domain-containing protein 1 OS=Homo sapiens GN=RHBDD1 PE=2 SV=1  ali follow..  10  74..............HHADDWHLYFNMASMLWKGINLERRLGSRWF---AYVITAFSVLTGVVYLLLQFAVAEFMDEPDFKRSCA-----VGFSGVLFALKVLNNHYCPGGFVNRFACWVELVAIHLFSPGTSFAGHLAGILV---GL............... 203
7 -10.400sp|Q9H300|PARL_HUMAN Presenilins-associated rhomboid-like protein, mitochondrial OS=Homo sapiens GN=PARL PE=1 SV=2  ali follow..  11  215..............SHFSLFHMAANMYVLWSFSSSIVNILGQEQF---MAVYLSAGVISNFVSYVGKVATGRYGPSLGASGAI------MTVLAAVCTKILAIIFLPMFTFTAGNALKAIIAMDTAGMILFDHAAHLGGALF---GI............... 343
8 -10.300sp|O75783|RHBL1_HUMAN Rhomboid-related protein 1 OS=Homo sapiens GN=RHBDL1 PE=2 SV=1  ali follow..  11  254..............MHVGLEQL-LLQLMIGVPLELAGVLAGSLTVSITDMRAPVVGGSGGVYALCSAHLANVVMNWAGMRCPYKLLRMVLALVCMSSEVGRAVW-------------LRFSPPLPASGPQPSFMAHLAGAVV---GV............... 385
9 -10.000sp|Q6ZNA5|FRRS1_HUMAN(removed signalp:1-22) Ferric-chelate reductase 1 OS=Homo sapiens GN=FRRS1 PE=2 SV=2  ali follow..  13  349.............KVHGALM-VSIGVLVARFFKPV-AFLLGEAAWFQVHRMLMFTTTVLTCIAFVMPFIYRGGWSRHAGY------HPYLGCIVMTLAVLLAVFRPPLHDPRRQMFNWTHWSMGTAARIIAVAAMFLGMDL..................... 481
10 -9.960sp|P58872|RHBL3_HUMAN Rhomboid-related protein 3 OS=Homo sapiens GN=RHBDL3 PE=2 SV=1  ali follow..  10  220..............MHAGIEHLGLNVVLQLLVVYVAGVVAGSLAVSVADMTAPVVGSSGGVYALVSAHLANIVMNWSGMKCQFKLLRMAVALICMSMEFGRAVW-------------LRFHPSAYPPCPHPSFVAHLGGVAV---GI............... 351
11 -9.650sp|Q92508|PIEZ1_HUMAN Protein PIEZO1 OS=Homo sapiens GN=FAM38A PE=1 SV=4  ali   7  17.................CLILYNVTVIISKNMLSLLACVFVEQMQTGFCWVIQLFS----LVCTVKGYYDPKEMMDRDQDCLLPVEEAGIIWDSVCFFFLLLQRRVF---------LSHYYLHVRADLQATALLASRGFALYNAANLKSIDFHRRIEEKSL. 147
12 -9.560sp|Q6NTF9|RHBD2_HUMAN Rhomboid domain-containing protein 2 OS=Homo sapiens GN=RHBDD2 PE=2 SV=2  ali follow..  10  69..............VYENPISLLCGAIIIWRFAGNFERTVGTVRH---CFFTVIFAIFSAIIFLSFEAVSSLSKLGEVED--------ARGFTPVAFAMLGVTTVRSRMRRAPSVLVPWLLLGASWLIPQTSFLSNVCGLSI---GL............... 194
13 -9.230sp|Q9NX52|RHBL2_HUMAN Rhomboid-related protein 2 OS=Homo sapiens GN=RHBDL2 PE=1 SV=2  ali follow..  10  129..............VHAGVQHILGNLCMQLVLVYLAGVIAGSLASSIFDPLRYLVGASGGVYALMGGYFMNVLVNFQEMIPAFGIFRLLIIILIIVLDMGFALYRRFFVPEDGSP---------------VSFAAHIAGGFA---GM............... 258
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Jaroszewski L, Slabinski L, Wooley J, Deacon AM, Lesley SA, Wilson IA, Godzik A. Genome pool strategy for structural coverage of protein families. Structure. 2008 Nov 12;16(11):1659-67.