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Query: [S] COG5650 Predicted integral membrane protein, from COG1018

Results of FFAS03 search in H.sapiens
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MDQKLDQQKVDRVSPGDSEPVARDFINAIGGRFGRFAQVGTQRFWTPLRVLITTSLVFLAMGFLTKANCIQGSRGTDGVVSLNWSGSRQYTSACYNDIVPLYGGRGIDAPGFPYAFSWQEGDLTRYMEYPVLGGIFQWICGIITRFLYPVVDVIPFHTLPESGLYFIVTALALAFFWVLVIRMMVELTGNRVWDTVLVAASPLVAVHAFTNWDTPAIAAVIGAMLAVKRGNPLVAGVLIGAGTAFKLWPLYLLGAYLVLAVKNKNLKPFITMAAAAAVTWLVVNVPVMIAYPKAWNEFLRLNRERGAEWTTIYQVIDRNLPINLNDPVLLNVLSFGLFGASCVAILILGLKVQRTPRVAELAFLIVAAFLLFNKVWSPQYSLWLVPLAVLAFPQWKVLFPWMVTDAMVWPILMWHMLGTDNKGLPHEMLDLIVISRDAFIVVMIVGVIRQMLGRRADPVMDAHAGRDLLAGPFGAGERRKALKEVSLast
1 -43.200sp|Q9H3S5|PIGM_HUMAN GPI mannosyltransferase 1 OS=Homo sapiens GN=PIGM PE=1 SV=1  ali follow..  14  2..............................GSTKHWGEWLLNLKVAPAGVFGVAFLARVALVFYGV--------------------QDRTLHVRYTDIDYQVFTDA-----ARFVTEGRSPYLRATYRYTPLLGWLLTPNIYLSELFG-------------KFLFISCDLLTAFLLYRLLLLKGLGRRQACGYCVFWLLNPLPMAVSSRGNADSIVASLVLMVLYLIKKRLVACAAVFYGFAVHMKIYPVTYILPITLHLLPDRDNRAVLLFVAVAGLTFFALSFGFYYEYGWEFLEFYHLTRRDIRHNFSPYFYMLYLTA----ESKWSFSLGIAAFLPQLILLSAVSFAYYR--DLVFCCFLHTSIFVTFNKVCTSQYFLWYLCLLPLVMPLVRMPWKRAVVLLMLWFIAMWLAPAYVLEFQGKNTFLFIWLAGLFFLLINCSILIQIISHYKEEPLTERIKYD.................... 423
2 -25.600sp|Q9H490|PIGU_HUMAN(removed signalp:1-17) Phosphatidylinositol glycan anchor biosynthesis class U protein OS=Homo sapiens GN=PIGU PE=1 SV=3  ali follow..  6  12.......................................................................................SERVEVVSPLSSWKRVVEGLS-----LLDLGVSPYSGAVFHETPLIIYLFHFLIDYAE-------------LVFMITDALTAIALYFAIQDFNKVVFKKQKLLLKVALFYLLNPYTILSCVAKSTCAINNTLIAFFILTTIKGSAFLSAIFLALATYQSLYPLTLFVPGLLYLLQRQYIFSWEYAMMYVGSLVVIICLSFFLLSSWDFIPAFILSVPDLTPNIGLFWYFFAEMF-----EHFSLFFVCVFQINVFFYTIPLAIKLKEHPIF--FMFIQIAVIAIFKSYPTVGDVALYMAFFPVWNHLYRFLRNIFVLTCIIIVCSVLWHLWIYAGSANSNFFYAITLTFNVGQILLISDYFYAFLRREYY............................. 398
3 -19.800sp|Q92685|ALG3_HUMAN Dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichyl mannosyltransferase OS=Homo sapiens GN=ALG3 PE=1 SV=1  ali follow..  9  1MAAGLRKRGRSGSAAQAEGLCKQWLQRAWQ-----RLLLREPRYTLLVAACLCLAEVGITFWVIHRVA--------------------------YTEIDYMAEVEGVINGTYDYT---QLQGDTGPLVYPAGFVYIFMGLYYATSRGTDIRMAQ----------NIFAVLYLATLLLVFLIYHQTCKVPPFVFFFMCCASYRVHSIFVLRLFDPVAMVLLFLSINLLLAQRWGWGCCFFSLAVSVKMNVLLFAPGLLFLLLTQFGFRGALPKLGICAGLQVVLGLPFLLENPSGYLS--SFDLGRQFLFH--WTVNWRFLPEALFLHRAFHLALLTAHLTLLLLFALCRWHRTGPNQIVSTLFTSNFIGICFSRSLHYQFYVWYLPYLLWAMPARWLTHLLRLLVLGLIELSWNTYPSTSCSSAALHICHAVILLQLWL............................................... 422
4 -17.300sp|Q9Y672|ALG6_HUMAN(removed signalp:1-22) Dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase OS=Homo sapiens GN=ALG6 PE=1 SV=1  ali follow..  10  13..............................................................................................FGDYEAQRHWQEITFNL--YFNSSDNNLQYWGLDYPPLTAYHSLLCAYVAKFIGYESQAHKLFMRTTVLIADLLIYIPAVVLYCCCLKEISTKKKIANALCILLYPGLILIDYGHFQYNSVSLGFALWGVLGISCDCDLLGSLAFCLAINYKQMELYHALPFFCFLLGKKGFVLLVKLACIVVASFVLCWLPFFTE-LQVLRRLFPVDRG-EDKVANIWCSFNVFIKDILPRHIQLIMSFCFTFLSLLPACIKLILQPSSKGFKFTLVSCALSFFLFSFQVHEKSILLVSLPVCLVLSEIPFMSTWFLLVSTFSMLPLL......................................................................... 359
5 -16.600sp|Q9BVK2|ALG8_HUMAN(removed signalp:1-34) Probable dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase OS=Homo sapiens GN=ALG8 PE=1 SV=2  ali follow..  12  1...............................................................................................TDFEVHRNWLAITHSL-PISQWYYEATSEWTLDYPPFFAWFEYILSHVAKNVHNLNYSSSRTLLFQRFSVIFMDVLFVYAVRECCKCIDGKKVGKELSVLLLWNFGLLIVDHIHFQYNGFLFGLMLLSIARLFQKRHMEGAFLFAVLLHFKHIYLYVAPAYGVYLLRS-SFVRVISLGLVVFLVSALSLGPFLALNQLPQVFSRLFPFKRGLCHANFWALYNALFQHTVLPSVTPLATLICTLIAILPSIFCLWFKPQGPRGFLRCLTLCALSSFMFGHVHEKAILLAILPMSLLSVGKAGDASIFLILTTTGHYSLF......................................................................... 384
6 -16.500sp|Q92521|PIGB_HUMAN GPI mannosyltransferase 3 OS=Homo sapiens GN=PIGB PE=2 SV=1  ali follow..  7  15.GDASLTLHGLQNRSHGKIKLRKRKSTLYFNTQEKSARRRGDLLGENIYLLLFTIALRILNCFLVQT----------------SFVPDEY----WQSLEVSHH---------------VFNYGYLTWEWTERLRSYTYPLIFASIYKILHLLGKDSVQLLIWIPRLAQALLSAVADVRLYSLMKQLENQEVARWVFFCQLCSWFTWYCCTRTNTMETVLTIIALFYYPLEGSVKYSSLVALAFIIRPTAVILWTPLLFRHFCQEPRKLDLILHHFLPVGFVTLSLSLMI-------DRIFFGQWTLVQFNFLFNVLQNWGTFYGSHPWHWYFSQGFPVILGTHLPFFIHGCYLAPKRYRILLVTVLWTLLVYSMLSHKEFIYPVLPFCMVFC.............................................................................................. 374
7 -15.800sp|Q9UKY4|POMT2_HUMAN Protein O-mannosyl-transferase 2 OS=Homo sapiens GN=POMT2 PE=1 SV=2  ali   10  12.SELRPRRGRCGPQAARAAGRDVAAEAVARSPKRPAWGSRRFEAVGWWALLALVTLLSFATRFHR----------------------DEPPHICWDETHFGKMGSYYINRTFFF--------------HPPLGKMLIGLAGYLSGFQKPGDKYEHHSYMGMRGFCAFLGSWLVPFAYLTVLDLSKSLSAALLTAALLTFDTGCLTLSQYILLDPILMFFIMAAMLSMVKYNLSLTGVSLAGALGVKFVGLFIILQVGLNTILSLSLVTVGKHLTARVLCLIVLPLALYTA.................................................................................................................................................................................................... 296
8 -13.600sp|Q86VD9|PIGZ_HUMAN GPI mannosyltransferase 4 OS=Homo sapiens GN=PIGZ PE=2 SV=4  ali follow..  10  2...........QICGSSVASVAAGTSFQVLGPVCWQQLDLKMAVRVLWGGLSLLRVLWCLL------------------PQTGYVHPDEF----FQSPEVMAEDILGVQAARPWEFYPSSSCRS--VLFPLLISGSTFWLLRLWEELGPWPGLVSGYALLVG----LLLTALSFALDGAVYHLAPPMGADRWNALALLSGSYVTLVFYTRTFNTIEGLLFTWLLVLVPRWRSWLLGGIVAAGFFNRTFLAFAVVPLYLWGTRNPGLKSLTREALVLLPGAALTAAVFVATDSWYFSSPATSRNLVLTPVNFLYNLNPQNLARHGTHARLTHLAVNGFLLFGVLHAQALQ-LLSSPRSYLLLLYFMPLALLSAFSHQEARFLIPLLVPLVLLCSPQTQPVPWKGTVVLFNALGALLFGCLHQGGLVPGLEYL....................................................... 442
9 -13.500sp|Q9NUD9|PIGV_HUMAN GPI mannosyltransferase 2 OS=Homo sapiens GN=PIGV PE=1 SV=1  ali follow..  8  5........................................DPSRKEVLRFAVSCRILTLMLQAL--FNAIIPDHHAEAFSPPRLAPSGFVDQLVEGD--AEHFLFIAEHG---YLYEHNFAF------FPGFPLALLVGTELLRPLRGLLSLRSCLLISVASLNFLFFMLAAVALHDLGCLVLHCPHQSFYAALLFCLSPANVFLAAGYS--EALFALLTFSAMGQLERGRVWTSVLLFAFATGVRSNGLVSVGFLMHSQCQGFFSSLTMLNPLRQLFKLMASLFLSVFTLGLPFALFQYYAYTQFCLPGSARPIPEPLVQLAVDKGYRIAEGNEPPWCFWDVPLIYSYIQDV----------VGFLKYYELKQV--PNFLL-AAPVAILVAWATWTYVTTHPWLCLTLGLQ----EKPDLGFLSPQVFVYVVHAAVLLLFGGLCMHVQVLTR................................. 404
10 -13.200sp|Q9UKY4|POMT2_HUMAN Protein O-mannosyl-transferase 2 OS=Homo sapiens GN=POMT2 PE=1 SV=2  ali   13  1.......................................................................................................................................................................LGSWLVPFAYLTVLDLSKSLSAALLTAALLTFDTGCLTLSQYILLDPILMFFIMAAMLSMVKYNLSLTGVSLAGALGVKFVGLFIILQVGLNTILSLSLVTVGKHLTARVLCLIVLPLALYTA.................................................................................................................................................................................................... 146
11 -13.100sp|Q9Y6A1|POMT1_HUMAN(removed signalp:1-37) Protein O-mannosyl-transferase 1 OS=Homo sapiens GN=POMT1 PE=1 SV=2  ali   10  2...........................................................................................AVVFDEVYYGQYISFYMKQIFFLDD------------GPPFGHMVLALGGYLGGFDGNFLWNRIGAEYSSNVPVWLAGALSVPMAYQIVLELHFSHCAAMGAALLMLIENALITQSRLMLLESVLIFFNLLAVLSYLKFFLTLTGVACSCAVGIKYMGVFTYVLVLGVAA................................................................................................................................................................................................................................. 182
12 -11.200sp|Q5BKT4|AG10A_HUMAN(removed signalp:1-30) Alpha-1,2-glucosyltransferase ALG10-A OS=Homo sapiens GN=ALG10 PE=1 SV=1  ali follow..  10  5..............................................................................................YMDIFHLPQAQRYCEGHFSLSQ-------DPMITTLPGLYLVSIGVIKPAIWIFGWSEHVVCSIGMLRFVNLLFSVGNFYLLYLLFCKVQPRNKAQRVLSTLTLAVFPTLYFFNFLYYEAGSMFFTLFAYLMCLYGNHKTSAFLGFCGFMFRQTNIIWAVFCAGNVIAQKLTEAWKTLLGFLFCAFVVVNGGIVIGDRSSHEACLHFPQLFYFFSFTLFFSFPHLLSPSKIKTFLSLVWKRRILFFVVTLVSVFLVWKSKSIFWNLMFFICLFTVIVPQKLLEFRYFI--LPYVIYRLNIPLPPTSRLICELSCYAVV.......................................................................... 417
13 -11.100sp|Q5I7T1|AG10B_HUMAN(removed signalp:1-30) Putative alpha-1,2-glucosyltransferase ALG10-B OS=Homo sapiens GN=ALG10B PE=1 SV=2  ali follow..  11  5..............................................................................................YMDIFHLPQAQRYCEGHFSLSQ-------DPMITTLPGLYLVSVGVVKPAIWIFAWSEHVVCSIGMLRFVNLLFSVGNFYLLYLLFHKVQPRNKAASSIQRVLLAVFPTLYFFNFLYYEAGSMFFTLFAYLMCLYGNHKTSAFLGFCGFMFRQTNIIWAVFCAGNVIAQKLTEAWKTLLGFLFCAFVVVNGGIVIGDRSSHEACLHFPQLFYFFSFTLFFSFPHLLSPSKIKTFLSLVWKHGILFLVVTLVSVFLVWKSKPIFWNLMFFICLFIVIVPQKLLEFRYFI--LPYVIYRLNITLPPTSRLVCELSCYAIV.......................................................................... 417
14 -10.800sp|Q8TCJ2|STT3B_HUMAN Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B OS=Homo sapiens GN=STT3B PE=1 SV=1  ali   9  28.NSRHGHHGPGAQCAHKAAGGAAPPKPAPAGLSGGLSQPAGWQSLLSFTILFLAWLAGFSSRLFA---------------------IRFESIIHEFD----WFNYRSTHHLASHGFYEFLNWFDERAWYP----PGLMITAGLIHWILNTLNITVHIRDVCVFLAPTFSGLTSISTFLLTRELWNQGAG--LLAACFIAIVPGYISRSVAGSEGIAIFALQFTYYLWVKS-TMCCCLSYFYMVSAWGGYVFIINLIPLHVFVLLLMQRYSKRVYIAYSTFYIV........................................................................................................................................................................................................... 300
15 -10.700sp|Q9BV10|ALG12_HUMAN(removed signalp:1-28) Dolichyl-P-Man:Man(7)GlcNAc(2)-PP-dolichyl-alpha-1,6-mannosyltransferase OS=Homo sapiens GN=ALG12 PE=1 SV=1  ali follow..  14  47............................................................................................................................AVFSSPAVYVLSLLEMSKFY---------------SQLIVRGVLGLGVIFGLWTLQKEVRRHFGAMVATMFCWVTAMQFHLMFYCTRTNVLALPVVLLALAAWLRHEWARFIWLSAAIIVFRVELCLFLGLLLLLALGNRKVSVVRALRHAVPAGILCLGLTVAVDS----GKVLWYNTVLNKS--SNWGT---------SPLLWYFYSALPRGLGCSLLFIPLGLVDRRTHAPTVLALGFMALYLLPHKEL--RFIIYAFPMLNITA.............................................................................................. 296
16 -10.300sp|Q5T4D3|TMTC4_HUMAN Transmembrane and TPR repeat-containing protein 4 OS=Homo sapiens GN=TMTC4 PE=1 SV=2  ali   13  20...................................................FWAKLVVGSVAIVCFARSYDGDF-------------------VFDDSEAIVNNKDLQAETP--FWGSRLSSNTSHKSYRPLTVLTFRINYYLSGGFHPVVVNILLHSGISVLMVDVFSVLFGGLQYTSKGRRLHLAPRASLLAALLFAVHPVCVAGVVGRADLLCALFFLLSFLGYCKAFVLLSIFLGAVAMLCKEQGITVLGLNAVF................................................................................................................................................................................................................................... 234
17 -9.990sp|Q03403|TFF2_HUMAN(removed signalp:1-23) Trefoil factor 2 OS=Homo sapiens GN=TFF2 PE=1 SV=2  ali follow..  9  1.EKPSPCQCSRLSPHNRTNCGFPGITSDQCFDNGCCFDSSVTGVPWCFHPLPKQESDQCVMEVSDRRNCGYPGISPEECASRKFSNFIFEVPWCFFPKSV.................................................................................................................................................................................................................................................................................................................................................................................................. 101
18 -9.560sp|Q6ZXV5|TMTC3_HUMAN Transmembrane and TPR repeat-containing protein 3 OS=Homo sapiens GN=TMTC3 PE=1 SV=2  ali   8  6...................................................LKEITLIVGVVTACYWNSLFCGF-------------------VFDDVSAILDNKDLHPSTP--FWGTPMSEERSHKSYRPLTVLTFRLNYLLSELKPMSYH----------LLNMIFHAVVSVIFLKVCKLFLDNKSSVIASLLFAVHPIHTAVTGVVGRAELLSSIFFLAAFLSYTRSKIALTVFLVAVATLCKEQGITVVGICCVY................................................................................................................................................................................................................................... 201
19 -9.430sp|Q9GZM5|YIPF3_HUMAN Protein YIPF3 OS=Homo sapiens GN=YIPF3 PE=1 SV=1  ali follow..  10  121..............................................................................................YFDVEPAQVRSRLLESMIPIKMVNFPQKIAGELYGPLMLVFTLVAILLHGMKTSDTIIREGTLMGTAIGTCFGYWLGVSSFIYFLAYLCNAQ--------------ITMLQMLALLGYGLFGHCIVLFITYNIHLHALFYLFWLLVGGLST-----LRMVAVLVSRTVGPTQRLLLCGTLAALHMLFLLYLHFAYHK................................................................................................................................................................................................... 298
20 -9.420sp|Q8N394|TMTC2_HUMAN(removed signalp:1-21) Transmembrane and TPR repeat-containing protein 2 OS=Homo sapiens GN=TMTC2 PE=2 SV=1  ali   10  4..............................................................................................YDDSRAIKTNQDLLPETP--FWGTLLTHSGSHKSYRPLCTLSFRLNHAIGGLNPWSYH----------LVNVLLHAAVTGLFTSFSKILLGDGYWT-FMAGLMFASHPIAVAGIVGRADVGASLFFLLSLLCYIKHCFLGSGLCAGCSMLWKEQGVTVLAVSAVY................................................................................................................................................................................................................................... 178
FFAS is supported by the NIH grant R01-GM087218-01
1 4 8 3 1 9   jobs submitted since Jan 1, 2011
Comments and questions to: webmaster
Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Ye Y, Godzik A. Multiple flexible structure alignment using partial order graphs. Bioinformatics. 2005 Mar 3;