FFAS03 results for KOG0068

Query: [E] KOG0068 D-3-phosphoglycerate dehydrogenase, D-isomer-specific 2-hydroxy acid dehydrogenase superfamily, from COG1018

Results of FFAS03 search in H.sapiens
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.

						. 10 . 20 . 30 . 40 . 50 . 60 . 70 . 80 . 90 . 100 . 110 . 120 . 130 . 140 . 150 . 160 . 170 . 180 . 190 . 200 . 210 . 220 . 230 . 240 . 250 . 260 . 270 . 280 . 290 . 300 . 310 . 320 . 330 . 340 . 350 . 360 . 370 . 380 . 390 . 400 . 410 . 420 . 430 . 440 . 450 . 460 . 470 . 480 . 490 . 500 . 510 . 520 . 530 . 540 . 550 . 560 . 570 . 580 . 590 . 600 . 610 . 620
#	Score	Template	Links and tools	%id	First	MAFSSSCSSVKAVNSRWTSPSPSPSSRFAVLPAFLHRRYATSVKLTAISAALKTVEQTTLTEDNRFSTVGSDSDEYNPTLPKPRILVTEKLGEAGVNLLREFGDVDCSYDLSPEDLKKKVAESDALIVRSGTKVTREVFEAAKGRLKVVGRAGVGIDNVDLQAATEHGCLVVNAPTANTVAAAEHGIALLASMARNVAQADASIKAGKWERSKYVGVSLVGKTLAVMGFGKVGTEVARRAKGLGMTVISHDPYAPADRARALGVDLVSFDQAISTADFVSLHMPLTPATKKVFNDETFSKMKKGVRLINVARGGVIDEDALVRALDAGIVAQAALDVFCEEPPSKDSRLIQHENVTVTPHLGASTKEAQEGVAIEIAEAVAGALKGELSATAVNAPMVAPEVLSELTPYIVLAEKLGRLAVQLASGGKGVQSIRVVYRSARDRDDLDTRLLRAMITKGIIEPISDSYVNLVNADFIAKQKGLRISEERMVVDSSPEYPVDSIQVQILNVESNFAGAVSDAGDISIEGKVKYGVPHLTCVGSFGVDVSLEGNLILCRQVDQPGMIGQVGNILGEQNVNVNFMSVGRTVLRKQAIMAIGVDEEPDNKTLERIGGVSAIEEFVFLKL	Last
1	-118.000	`sp\|O43175\|SERA_HUMAN D-3-phosphoglycerate dehydrogenase OS=Homo sapiens GN=PHGDH PE=1 SV=4`	`ali follow..`	34	5	................................................................................NLRKVLISDSLDPCCRKILQDGGQVVEKQNLSKEELIAELQDCEGLIVRSATKVTADVINAAE-KLQVVGRAGTGVDNVDLEAATRKGILVMNTPNGNSLSAAELTCGMIMCLARQIPQATASMKDGKWERKKFMGTELNGKTLGILGLGRIGREVATRMQSFGMKTIGYDPIISPEVSASFGVQQLPLEEIWPLCDFITVHTPLLPSTTGLLNDNTFAQCKKGVRVVNCARGGIVDEGALLRALQSGQCAGAALDVFTEEPPR-DRALVDHENVISCPHLGASTKEAQSRCGEEIAVQFVDMVKGKSLTGVVNAQALTSAFSPHTKPWIGLAEALGTLMRAWAGS--PKGTIQVITQG--TSLKNAGNCLSPAVIVGLLKEASKQDVNLVNAKLLVKEAGLNVTTSHSPAAP---GEQGFGECLLA--------VALAGAPYQAVGLVQGTTPVLQGLNGAVFRPEDLPLLLFRTQTSDPAMLPTMIGLLAEAGVRLLSYQTSLVS-DGETWHVMGISSLLPSLEA----WKQHVTEAFQFHF	533
2	-88.000	`sp\|P56545\|CTBP2_HUMAN C-terminal-binding protein 2 OS=Homo sapiens GN=CTBP2 PE=1 SV=1`	`ali follow..`	26	33	.................................................................................RPLVALLDGRDTVEMPILKDLATVAFDAQSTQEIHEKVLNEAVGAMMYHTITLTREDLEKFK-ALRVIVRIGSGYDNVDIKAAGELGIAVCNIPSAAVEETADSTICHILNLYRRNTWLYQALREGTRVQSASGAARIRGETLGLIGFGRTGQAVAVRAKAFGFSVIFYDPYLQDGIERSLGVQRVTLQDLLYQSDCVSLHCNLNEHNHHLINDFTIKQMRQGAFLVNAARGGLVDEKALAQALKEGRIRGAALDVHESEPFSAQGPLKDAPNLICTPHTAWYSEQASLEMREAAATEIRRAITGRIPESLRNC--VNKEFFVTSAPWSVIDQQAIH---------PELNGATYRYPP--GIVGVAPGGLP-AAMEGIIPGGIPVTHNLPTVAHPSQAPSPNQPTKHGDNREHPN................................................................................................................................	443
3	-87.000	`sp\|Q13363\|CTBP1_HUMAN C-terminal-binding protein 1 OS=Homo sapiens GN=CTBP1 PE=1 SV=2`	`ali follow..`	24	21	...........................................................................NGPLHPRPLVALLDRDCTVEMPILKDVATVAFDAQSTQEIHEKVLNEAVGALMYHTITLTREDLEKFK-ALRIIVRIGSGFDNIDIKSAGDLGIAVCNVPAASVEETADSTLCHILNLYRRATWLHQALREGTRVQSASGAARIRGETLGIIGLGRVGQAVALRAKAFGFNVLFYDPYLSDGVERALGLQRVTLQDLLFHSDCVTLHCGLNEHNHHLINDFTVKQMRQGAFLVNTARGGLVDEKALAQALKEGRIRGAALDVHESEPFSSQGPLKDAPNLICTPHAAWYSEQASIEMREEAAREIRRAITGRIPDSLKNCVNK---------DHLTAATHWASMDPAVVHP--ELNGAAYRYPP--GVVGVAPTGIPAAVEGIVPSAMLSHGLPPVAHPPHAPSPGQTVKPEADRDHASDQ................................................................................................................................	439
4	-83.900	`sp\|Q9UBQ7\|GRHPR_HUMAN Glyoxylate reductase/hydroxypyruvate reductase OS=Homo sapiens GN=GRHPR PE=1 SV=1`	`ali follow..`	27	2	.............................................................................RPVRLMKVFVTRRIPAEGRVALARAADCEVDEPIPAKELERGVAGAHGLLCLLSDHVDKRILDAAGANLKVISTMSVGIDHLALDEIKKRGIRVGYTPDVLTDTTAELAVSLLLTTCRRLPEAIEEVKNGGWTSWKLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQRPEEAAEFQAEFVSTPELAAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVFINISRGDVVNQDDLYQALASGKIAAAGLDVTSPEPLPTNHPLLTLKNCVILPHIGSATHRTRNTMSLLAANNLLAGLRGEPMPSELKL.....................................................................................................................................................................................................................................	328
5	-13.200	`sp\|Q96HN2\|SAHH3_HUMAN Putative adenosylhomocysteinase 3 OS=Homo sapiens GN=AHCYL2 PE=1 SV=1`	`ali`	15	6	.............................................................................................................................MILDDGGDLTHWIYKKYPNMFKIVEESVTGVHRLQLSKAGKLCVPAMNVNDSVTKQKFDNLYCCRESILDGL--------------KRTTDMMFGGKQVVVCGYGEVGKGCCAALKAMGSIVYVTEI-ICALQACMDGFRLVKLNEVIRQVDIVIT----CTGNKNVVTREHLDRMKNSCIVCNMGHSNTIDVASLRTPELTWE-EGRLLNLSCSTVPTFVLSITATTQALALIELYNAPEGRYKQDVYLLPKKMDEYVASLHLPTFAHLTELTDEQAK----YLGLNK..................................................................................................................................................................................................................	300
6	-12.500	`sp\|O43865\|SAHH2_HUMAN Putative adenosylhomocysteinase 2 OS=Homo sapiens GN=AHCYL1 PE=1 SV=2`	`ali follow..`	18	186	......................................................................................VAAALAEAGVAVFAWKGESEDDFWWCIDRCVNMDGWQANMILDDGGDLTHWVYKKYPNVFKIVEESVTGVHRLQLSKAGKLCVPAMNVNDSVTKQKFDNLYCCRESILDGLKRT--------------TDVMFGGKQVVVCGYGEVGKGCCAALKALGAIVYITE--ICALQACMDGFRVVKLNEVIRQVDVVIT----CTGNKNVVTREHLDRMKNSCIVCNMGH----NTEIDVTSLRTPELTGRLLNLSCSTVPTFVLSITATTQALALQDVYLLPKKMDEYVASLHLPSFDAHLT...............................................................................................................................................................................................................................................	505
7	-12.000	`sp\|Q96HN2\|SAHH3_HUMAN Putative adenosylhomocysteinase 3 OS=Homo sapiens GN=AHCYL2 PE=1 SV=1`	`ali`	17	117	......................................................................................VAAALAESGFPVFAWKGESEDDFWWCIDRCVNVEGWQPNMILDDGGDLTHWIYKKYPNMFKIVEESVTGVHRLYLSKAGKLCVPAMNVNDSVTKQKFDNLYCCRESILDGLKRT--------------TDMMFGGKQVVVCGYGEVGKGCCAALKAMGSIVYVTEI-ICALQACMDGFRLVKLNEVIRQVDI..........................................................................................................................................................................................................................................................................................................................................................	300
8	-11.900	`sp\|P23526\|SAHH_HUMAN Adenosylhomocysteinase OS=Homo sapiens GN=AHCY PE=1 SV=4`	`ali follow..`	16	88	......................................................................................AAAAIAKAGIPVYAWKGETDEEYLWCIEQTLYFKDGPLNMILDDGGDLTNLIHTKYPQLLPISEETTTGVHNLKMMANGILKVPAINVNDSVTKSKFDNLYGCRESLIDGIKRA--------------TDVMIAGKVAVVAGYGDVGKGCAQALRGFGARVIITE--INALQAAMEGYEVTTMDEACQEGNIFVT----TTGCIDIILGRHFEQMKDDAIVCNIGHFDVIDVKWLNENAVEKVNIKPQVDRYRLKNGRRIILLAE--NLGCAMGHPSFVMSNSFTNQVMAQIELWT..................................................................................................................................................................................................................................................	374
9	-7.760	`sp\|Q49A26\|GLYR1_HUMAN Putative oxidoreductase GLYR1 OS=Homo sapiens GN=GLYR1 PE=1 SV=3`	`ali follow..`	13	268	.............................................................................................................................................................................................................................KKIGFLGLGLMGSGIVSNLLKMGHTVTVWNRTAEKDLFIQEGARLGTPAEVVSTCDITFACVSDPKAAKDLVLGPSLQGIRPGKCYVDMSTVDADTVTELAQVIVSRGGR------FLEAPVSGNQQLSNDGMLVILAAGDRGLYEDCSSCFQAMGKTSFFL-NAAKMMLIVNM--VQGSFMATIAEGLTLAHVTG------QSQQTLLDILNQGQLASIFLDQKCQNILQGNFKPDFYLKYIQKDLRL--AIALGDAVNHPT............................................................................................................................................	521
10	-7.320	`sp\|P31937\|3HIDH_HUMAN 3-hydroxyisobutyrate dehydrogenase, mitochondrial OS=Homo sapiens GN=HIBADH PE=1 SV=2`	`ali follow..`	17	40	.............................................................................................................................................................................................................................TPVGFIGLGNMGNPMAKNLMKHGYPLIIYDVFPDAKEFQDAGEQVVSPADVAEKADRIITMLPTSINAIEAYSGANLKKVKKGSLLIDSSTIDPAVSKELAKEVEKMGAV---MDA----PVSGGVGAARSGNLTFMVGGVEDEFAAAQELLGCMGSNVVYC-TGQAAKICNNM--LLAISMIGTAEAMNLGIRLGLDPKLLAK.......................................................................................................................................................................................................	242

FFAS is supported by the NIH grant R01-GM087218-01

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