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Query: [K] KOG2181 LIM domain binding protein LDB1/NLI/CLIM, from COG1018

Results of FFAS03 search in H.sapiens
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MCVVIFLKFLFSDNGNNQHGTEAAFGRLAQSYRIQDLLFIIVIFFRAIHIMMFHRPPSARPPLNHVDQLKSLQATALGKPGMRSQATEPQPIGNTVSPLEFRIHDMNRRLYIFSSTGVSENDQQQWWDAFSHEFFDDDCKLWFVIGSEPVAFASRERYIINRQFIPKFFRSIFDSGMRELQYVLRGPSRECTLANGSQAYENENVLQITRYDQSSQFEVNTEGKLYVEFAPFDEVMNYRIKAWTLELKRSNEFVYNQNTADYRVEAQNPEQENKPRMGFFKSTFNLMTMLKILDPMQSIMSSAKSAPAITPREVMKRTLFQHHQVRQQNMRQQQLNQQMMIPAPEPEKPKPARKRQRKPAANPRGSKKATAAAAAAAAAATNGVPPTVPTASPANNQQFPPNPMTSQFQQMSYPDVMVVGEPSMMGSEFGENDERTISRVENSQYDPNAMQMQSLGQGPNSSMNINGRNMMNQHHPGMQPPPGQQHMPPHSMGSQMPTSMHNPMHMPPGSMQGHGGMPPMPSTMANQMPPPNLPPHTMSNQMPNSRMPPMQGQMPPSGMPGQMSNPNMMGSGMPPMSMSSQMPGSMSNPMPNQMPGGMQMNQMPPPNYSQYTGGPPPQWPPPNSAMITGLast
1 -38.200sp|O43679|LDB2_HUMAN LIM domain-binding protein 2 OS=Homo sapiens GN=LDB2 PE=1 SV=1  ali follow..  23  2........................................................................SSTPHDPFYSSPFGPFYRRHTPYMVQPEYRIYEMNKRL-----QSRTEDSDNLWWDAFATEFFEDDATLTLSFCLED----GPKRYTIGRTLIPRYFSTVFEGGVTDLYYILKHSKESYH--NSSITVDCDQCTMVTQHGKPMFTKVCTEGRLILEFTFDDLM---RIKTWHFTIRQYRELVPRSILAMHDPQVLDQLSKNITRMGLTNFTLNYLRLCVILEPMQELMSRHKTY-NLSPRDCLKTCLFQKWQRMVAPPAEPTRQPTTKRRKRKNSTSSTSNSSAGNNANSTGSKKKTTAANLSLSSQVPDVMVVGEPTLMGGEFGDEDERLITRLENTQYDAANGMDDEEDFNNSPALGNNSPWNSKPPATQETKSENPPPQASQ............................................................................................................................................................................ 373
2 -37.800sp|Q86U70|LDB1_HUMAN LIM domain-binding protein 1 OS=Homo sapiens GN=LDB1 PE=1 SV=2  ali follow..  20  14.............................................SFKLYSPKEPPNGNAFPPFHPGTMLDRDVGPTPMYPPTYLEPGIGRHTPYGNQTDYRIFELNKRL-----QNWTEECDNLWWDAFTTEFFEDDAMLTITFCLED----GPKRYTIGRTLIPRYFRSIFEGGATELYYVLKHPKEAFH--SNFVSLDCDQGSMVTQHGKPMFTQVCVEGRLYLEFMFDDMM---RIKTWHFSIRQHRELIPRSILAMHDPQMLDQLSKNITRCGLSNSTLNYLRLCVILEPMQELMSRHKTY-SLSPRDCLKTCLFQKWQRMVAPPAEPTRQQPSKRRKRKMSGGSTMSSGGGNTNNSNSKKKSPASTFALSSQVPDVMVVGEPTLMGGEFGDEDERLITRLENTQFDAANGIDDEDSFNNSPALGANSPWNSKPPSSQESKSENPTSQAS.............................................................................................................................................................................. 410
3 -9.090sp|O75909|CCNK_HUMAN Cyclin-K OS=Homo sapiens GN=CCNK PE=1 SV=2  ali follow..  12  23.......CWYWDKK-SQLEGLDPA----EARYRREGARFI---------------------------------------------------------------FDVGTRLGLHYDTLAT---------IYFHRFYMFHSFKQF------------PRYVTGACCL--FLAGKVEETPKKCKDIIQFGQFGDDPKEEVMVLE-QTIKFDLQVEHPYQFLLKYAKQLKGDKNKIQKLVQM---AWTFVNDSLCQWEPEIIAVAVMYLAGRLCKFEIQEWT---QFVQDVPVDVLEDICHQILDLYSQGKQQMPHHTPHQLQQPPSLQPTPQVPQVQQSQPSQSSEPSQPQQKDPQQPAQQQQPAQQPKKPSPQPSSPRQVKRAVVVSPKEENKAAEPPPPKIPKIETTHPPLPPAHPPPDRKPPLAAALGEAEPPGPVDATDLPKVQIPPPAHPAPVHQPPPLPHRPPPPPPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYGALPPAYGPPAHLPYHPHVYPPNPPPPPVPPP---PASFPPPAIPPPTPGYPPPPPTYNPNFPPPPPRLPPTHAVPPHPPPGLGLPPASYPPPAVPPGGQPPVPPPIPPPGMPPVGGLGRAA.... 577
4 -8.090sp|Q14814|MEF2D_HUMAN Myocyte-specific enhancer factor 2D OS=Homo sapiens GN=MEF2D PE=1 SV=1  ali follow..  10  1M---IQIQRI-TDERNRQ----VTFGLMKKAYELSVLC-IALIIFNH-----------------------------------------------------------SNKLFQYASTDMDK-------------------------------------------VLLKYYNEPHESRTNA---IIETLRKKGFNGCDSPEPDGEDSLEQSPLLEDKYRRASEELDGLFR---------------RYGSTVPAPNFAMPVTVPVSNQSSLQFSNPSGSLVTPSLVTSSLTDPRLLSPQQPALQRNSVSPGLPQRPASAGAMLGGDLNSANGACPSPVGNGYVSARASPGLLPVANGNSLNKVIPAKSPPPPTHSTQLGAPSRKPDLRVITSQAGKGLMHHLTEDHLDLNNAQRLGVSQSTHSLTTPVVSVATPSLLSQGLPFSSMPTAYNTDYQLTSAELSSLPAFSSPGGLSLGNVTAWQQPQQPQQPQQPQPPQQQPPQPQQPQPQQPQQPQQPPQQQSHLVPVSLSNLIPGSPLPHVGAALTVTTHPHISIKSEPVSPSRERSPAPPPPAVFPAARPEPGDGLSSPAGGSYETGDRDDGRGDFGPTLGLLRPAPEPEAEGSAVKRM.. 513
5 -8.050sp|Q9UBW5|BIN2_HUMAN Bridging integrator 2 OS=Homo sapiens GN=BIN2 PE=1 SV=3  ali follow..  7  1..........MAEGKAGGKQVQKKFSRAQEKVETKDERF-----FY---------------------------------------------------QQQAEGHKLYKDLKNFLSAVKVMHESSKRVSETLQEIYSSEHEELKAIVWNNDLLWEDYEEKLADQAVT--YVAQFS----EIKERIAKRGRK--------LVDYDSARHHLEAVQNAKKK--------------DEAKTAKAEEEFNKAQTVFEDL-NQELLEELPILYNSRIGCYVTIFQNISNLRDVFYREMSKLNHNLYEVMSKLEKQHSNKVFVVKGLSSSSRRSLVISPPVRTATVSSPLTSPTSPSTLSLKSESESVSATEDLAPDAAQGEDNSEIKELLEEEEIEKEGSEASSSEEDEPLPACNGPAQAQPSPTTERAKSQEEVLPSSTTPSPGGALSPSGQPSSSATEVVLRTRTASEGSEQPKKRASIQRTSAPPSRPPPPRATASPRPSSGNIPSSPTASGGGSPTSPRASLGTGTASPRTSLEVSPNPEPPEKPVRTPEAKENENIHNQNPEELCTSPTLMTSQVASEPGEAKKMEDKEKDNKLISANSSEGQDQLQVSMVPENNNLTAPEPQEEVSTS. 560
6 -7.830sp|Q8N8W4|PLPL1_HUMAN Patatin-like phospholipase domain-containing protein 1 OS=Homo sapiens GN=PNPLA1 PE=2 SV=3  ali follow..  8  14......HSISFSGSG---QGTSA--GAVIAAIEMDEYLRVLNVGVAEVKKSFLGPLSPS--------------------------------------------CKMVQMMRQFLYRVLPEDSYKV--NVVVSEFTSKEELI---------------EALYCSCFVPVYCVRYIDGGFTG-------------------CAFWTDAITISTFSGQQDICPRDCPAIFHDFRMFNCSFQFSLEN----ARMTHALFPPD----------LVILHDYYYRGYED-AVLYLRRLNAVY-------------------------------------NSSSKRVIFPRVEVYCQIELALGNECPERSQPSLRARQASLEGATQPHKEWVPKGDGRGSHGPPVSQPVQTLEFTCESPVSAPVSPLEQPPAQPLASSTPLSLSGMPPVSFPAVHKPPSSTPGSSLPTPPPGLSPLSPQQQVQPSGSPARSLHSQAPTSPRPSLGPSTVGAPQTLPRSSLSAFPAQPPVEELGQEQPQAVALLVSSKPKSAVPLVHVKETVSKPYVTESPAEDSNWVNKVFKKNKQKTSGTRKGFPRHSGSKKPSSKV.............................. 531
7 -7.640sp|A6NJT0|UNC4_HUMAN Homeobox protein unc-4 homolog OS=Homo sapiens GN=UNCX PE=2 SV=1  ali follow..  9  95..................................................................................................................................................DPDKESPGCKR---------RRTRTNFTGQLEEL----------------------EKAFNESHY--P---DVFMREALALRLDLVES----RVQVW-FQNRRAK---RKKENTKKGPGRPAHNSHPTTCSGEPMDP----------EEIARKELEKMEKKKRKHEKKLLKSQGRHLHSPGGLSLHSAPSSDSDSGGGGLSPEPPEPPPPAAKGPGAHASGAAGTAPAPPGEPPAPGTCDPAFYPSQRSGAGPQPRPGRPADKDAASCGPGAAVAAVERGAAGLPKASPFSVESLLSDSPPRRKAASNAAAAAAAGLDFAPGLPCAPRTLIGKGHFLLYPITQPLGFLVPQAALKGGAGLEPAPKDAPPAPAVPPAPPAQASFGAFSGPGGAPDSAFARRSPDAVASPGAPAPAPAPFRDLASAAATEGGGGDCADAGTAGPAPPPPAPSPRPGPRPPSPAEEPATCGVPEPGAAAGPSPPEG 525
8 -7.570sp|Q06413|MEF2C_HUMAN Myocyte-specific enhancer factor 2C OS=Homo sapiens GN=MEF2C PE=1 SV=1  ali follow..  10  1M---IQITRI-MDERNRQ----VTFGLMKKAYELSVLC-IALIIFNS-----------------------------------------------------------TNKLFQYASTDMDK-------------------------------------------VLLKY----------------------------------------TEYNEPHESRTNSD------------------------VETLRKKGLNGCDSPDPDADDSVGHSPESEDKYRKINEDIDLMISRQRLCAVPPPNFEMPVSIPVSSHNSLVYSNPVSSLGNPNLLPLAHPSLQRNSMSPGVTHRPPSAGNTGGLMGGDLTSGAGTSAGNGYGNPRNSPGLLVSPGNLNKNMQAKSPPPMNLGMNNRKPDLRVLIPPGSKNTMPSVSEDVDLLLNQRINNSQSAQSLATPVVSVATPTLPGQGMGGYPSAISTTYGTEYSLSSADLSSLSGFNTASALHLGSVTGWQQQHLHNMPPSALSQLGACTSTHLSQSSNLSLPSTQSLNIKSEPVSPPRDRTTTPSRYPQHTRHEAGRSPVDSLSSCSSSYDGSDREDHRNEFHSPIGLTRPSPDERESPSVKRM.. 465
9 -7.560sp|O43670|ZN207_HUMAN Zinc finger protein 207 OS=Homo sapiens GN=ZNF207 PE=1 SV=1  ali follow..  11  1.........................................................................................................MGRK----------KKKQLKPWCWYCNRDFDDEKILI----------QHQK---------AKHFK-------------------------------CHIC------------KLYTGPGLAIHCMQVHKETIDAVPN-ELEI---MEGIPEKDMDERRRLLEQKTQESQKKKQQDDSDEYDDDDSAASTSFQPQPVQPQQGYIPPMAQPGLPPVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPGMPPGMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTATVPAPQPPVTKPLFPSAGQMGTPVTSSSTASSNSESLSASSKALFPSTAQAQAAVQGPVGTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSATSAQLPKYQRNLPRPGQAPIGNPPVGPIGGMMPPQPGIPQQQGMRPPMPPHGQYGGHHQGMPGYLPGAMPPYGQGPPMVPPYQGGPPRPPMGMRPPVMSQG 475
10 -7.520sp|Q02078|MEF2A_HUMAN Myocyte-specific enhancer factor 2A OS=Homo sapiens GN=MEF2A PE=1 SV=1  ali follow..  12  1M---IQITRI-MDERNRQ----VTFGLMKKAYELSVLC-IALIIFNS-----------------------------------------------------------SNKLFQYASTDMDK-------------------------------------------VLLKY----------------------------------------TEYNEP-----------------------------------HESRTNSDIVEALNKKEHRGCDSPDPDTSYVLTPHTEEKYKKINEEFDNMMRNHKIAPGLPPQNFSMSVTVPVTSPNALSYTNPGSSLVSPSLAASSTLTDSSMLSPPQTTLHRNVSPGAPQRPPSTGNAGGMLSTTDLTVPNGAGSSPVGNGFVNSRASPNLIGATGANSLGKVMPTKSPPPPGGGNLGMNSRKPDLRVVIPPSSKGMMPPLSEEEELELNTQRISSSQATQPLATPVVSVTTPSLPPQGLVYSAMPTAYNTDYSLTSADLSALQGFNSPGMLSLGQVSAWQQHHLGQAALSSLVAGGQLSQGSNLSINTNQNISIKSEPISPPRDRMTPSGFQQQQQQQQQQQPPPPPQPQPQPPQPQPRQEMGRSP. 454
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Li W, Godzik A. cd-hit: a fast program for clustering and comparing large sets of protein or nucleotide sequences. Bioinformatics. 2006 May 26;