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Query: [T] KOG2290 Rhomboid family proteins, from COG1018

Results of FFAS03 search in H.sapiens
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MSEARRDSTSSLQRKKPPWLKLDIPSAVPLTAEEPSFLQPLRRQAFLRSVSMPAETAHISSPHHELRRPVLQRQTSITQTIRRGTADWFGVSKDSDSTQKWQRKSIRHCSQRYGKLKPQVLRELDLPSQDNVSLTSTETPPPLYVGPCQLGMQKIIDPLARGRAFRVADDTAEGLSAPHTPVTPGAASLCSFSSSRSGFHRLPRRRKRESVAKMSFRAAAALMKGRSVRDGTFRRARRRSFTPASFLEEDTTDFPDELDTSFFAREGILHEELSTYPDEVFESPSEAALKDWEKAPEQADLTGGALDRSELERSHLMLPLERGWRKQKEGAAAPQPKVRLRQEVVSTAGPRRGQRIAVPVRKLFAREKRPYGLGMVGRLTNRTYRKRIDSFVKRQIEDMDDHRPFFTYWLTFVHSLVTILAVCIYGIAPVGFSQHETVDSVLRNRGVYENVKYVQQENFWIGPSSEALIHLGAKFSPCMRQDPQVHSFIRSAREREKHSACCVRNDRSGCVQTSEEECSSTLAVWVKWPIHPSAPELAGHKRQFGSVCHQDPRVCDEPSSEDPHEWPEDITKWPICTKNSAGNHTNHPHMDCVITGRPCCIGTKGRCEITSREYCDFMRGYFHEEATLCSQVHCMDDVCGLLPFLNPEVPDQFYRLWLSLFLHAGILHCLVSICFQMTVLRDLEKLAGWHRIAIIYLLSGVTGNLASAIFLPYRAEVGPAGSQFGILACLFVELFQSWQILARPWRAFFKLLAVVLFLFTFGLLPWIDNFAHISGFISGLFLSFAFLPYISFGKFDLYRKRCQIIIFQVVFLGLLAGLVVLFYVYPVRCEWCEFLTCIPFTDKFCEKYELDAQLHLast
1 -93.500sp|Q96CC6|RHDF1_HUMAN Rhomboid family member 1 OS=Homo sapiens GN=RHBDF1 PE=1 SV=2  ali   100  1..................................................................................................................................................................................................................................................................................................................................................................................................................................................................VKYVQQENFWIGPSSEALIHLGAKFSPCMRQDPQVHSFIRSAREREKHSACCVRNDRSGCVQTSEEECSSTLAVWVKWPIHPSAPELAGHKRQFGSVCHQDPRVCDEPSSEDPHEWPEDITKWPICTKNSAGNHTNHPHMDCVITGRPCCIGTKGRCEITSREYCDFMRGYFHEEATLCSQVHCMDDVCGLLPFLNPEVPDQFYRLWLSLFLHAGILHCLVSICFQMTVLRDLEKLAGWHRIAIIYLLSGVTGNLASAIFLPYRAEVGPAGSQFGILACLFVELFQSWQILARPWRAFFK......................................................................................................... 300
2 -90.500sp|Q6PJF5|RHDF2_HUMAN Rhomboid family member 2 OS=Homo sapiens GN=RHBDF2 PE=1 SV=2  ali   72  1....................................................................................................................................................................................................................................................................................................................................................................................................................................................................YIQQENFWVGPSSIDLIHLGAKFSPCIRKDGQIEQLVLRERDLERDSGCCVQNDHSGCIQTQRKDCSETLATFVKWQDDTGPPMDLGQKRTSGAVCHQDPRTCEEPASSGAHIWPDDITKWPICTEQARSNHTGFLHMDCEIKGRPCCIGTKGSCEITTREYCEFMHGYFHEEATLCSQVHCLDKVCGLLPFLNPEVPDQFYRLWLSLFLHAGVVHCLVSVVFQMTILRDLEKLAGWHRIAIIFILSGITGNLASAIFLPYRAEVGPAGSQFGLLACLFVELFQSWPLLERPWKAFL.......................................................................................................... 300
3 -90.000sp|Q96CC6|RHDF1_HUMAN Rhomboid family member 1 OS=Homo sapiens GN=RHBDF1 PE=1 SV=2  ali   100  1........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................IGTKGRCEITSREYCDFMRGYFHEEATLCSQVHCMDDVCGLLPFLNPEVPDQFYRLWLSLFLHAGILHCLVSICFQMTVLRDLEKLAGWHRIAIIYLLSGVTGNLASAIFLPYRAEVGPAGSQFGILACLFVELFQSWQILARPWRAFFKLLAVVLFLFTFGLLPWIDNFAHISGFISGLFLSFAFLPYISFGKFDLYRKRCQIIIFQVVFLGLLAGLVVLFYVYPVRCEWCEFLTCIPFTDKFCEKYELDAQLH 255
4 -89.200sp|Q6PJF5|RHDF2_HUMAN Rhomboid family member 2 OS=Homo sapiens GN=RHBDF2 PE=1 SV=2  ali   76  1.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................CIGTKGSCEITTREYCEFMHGYFHEEATLCSQVHCLDKVCGLLPFLNPEVPDQFYRLWLSLFLHAGVVHCLVSVVFQMTILRDLEKLAGWHRIAIIFILSGITGNLASAIFLPYRAEVGPAGSQFGLLACLFVELFQSWPLLERPWKAFLNLSAIVLFLFICGLLPWIDNIAHIFGFLSGLLLAFAFLPYITFGTSDKYRKRALILVSLLAFAGLFAALVLWLYIYPINWPWIEHLTCFPFTSRFCEKYELDQVLH 256
5 -71.500sp|Q96CC6|RHDF1_HUMAN Rhomboid family member 1 OS=Homo sapiens GN=RHBDF1 PE=1 SV=2  ali   100  1............................................................................................................................................................................................................................................................................................................LTGGALDRSELERSHLMLPLERGWRKQKEGAAAPQPKVRLRQEVVSTAGPRRGQRIAVPVRKLFAREKRPYGLGMVGRLTNRTYRKRIDSFVKRQIEDMDDHRPFFTYWLTFVHSLVTILAVCIYGIAPVGFSQHETVDSVLRNRGVYENVKYVQQENFWIGPSSEALIHLGAKFSPCMRQDPQVHSFIRSAREREKHSACCVRNDRSGCVQTSEEECSSTLAVWVKWPIHPSAPELAGHKRQFGSVCHQDPRVCDEPSSEDPHEWPEDITKWPICTKNSAGNHTNHPHMDCVITGRPCC............................................................................................................................................................................................................................................................... 300
6 -67.400sp|Q6PJF5|RHDF2_HUMAN Rhomboid family member 2 OS=Homo sapiens GN=RHBDF2 PE=1 SV=2  ali   51  1..................................................................................................................................................................................................................................................................................SMPDDVFESPPLSASYFRGIPHSASPVSPDGVQIPLKEYGRAPVPGPRRGKRIA----------------------------SKVKHFAFDRKKRHYGLGVVGNWLNRSYRRSISSTVQRQLESFDSHRPYFTYWLTFVHVIITLLVICTYGIAPVGFAQHVTTQLVLRNKGVYESVKYIQQENFWVGPSSIDLIHLGAKFSPCIRKDGQIEQLVLRERDLERDSGCCVQNDHSGCIQTQRKDCSETLATFVKWQDDTGPPMDKS-KRTSGAVCHQDPRTCEEPASSGAHIWPDDITKWPICTEQARSNHTGFLHMDCEIKGRPC................................................................................................................................................................................................................................................................ 300
7 -61.300sp|Q96CC6|RHDF1_HUMAN Rhomboid family member 1 OS=Homo sapiens GN=RHBDF1 PE=1 SV=2  ali   99  1MSEARRDSTSSLQRKKPPWLKLDIPSAVPLTAEEPSFLQPLRRQAFLRSVSMPAETAHISSPHHELRRPVLQRQTSITQTIRRGTADWFGVSKDSDSTQKWQRKSIRHCSQRYGKLKPQVLRELDLPSQDNVSLTSTETPPPLYVGPCQLGMQKIIDPLARGRAFRVADDTAEGLSAPHTPVTPGAASLCSFSSSRSGFHRLPRRRKRESVAKMSFRAAAALMKGRSVRDGTFRRAQRRSFTPASFLEEDTTDFPDELDTSFFAREGILHEELSTYPDEVFESPSEAALKDWEKAPEQAD........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 300
8 -60.000sp|Q96CC6|RHDF1_HUMAN Rhomboid family member 1 OS=Homo sapiens GN=RHBDF1 PE=1 SV=2  ali   99  1......................................................................................................................................................GMQKIIDPLARGRAFRVADDTAEGLSAPHTPVTPGAASLCSFSSSRSGFHRLPRRRKRESVAKMSFRAAAALMKGRSVRDGTFRRAQRRSFTPASFLEEDTTDFPDELDTSFFAREGILHEELSTYPDEVFESPSEAALKDWEKAPEQADLTGGALDRSELERSHLMLPLERGWRKQKEGAAAPQPKVRLRQEVVSTAGPRRGQRIAVPVRKLFAREKRPYGLGMVGRLTNRTYRKRIDSFVKRQIEDMDDHRPFFTYWLTFVHSLVTILAVCIYGIAPVGFSQHETVDSVLRNRGVYEN..................................................................................................................................................................................................................................................................................................................................................................................................................... 300
9 -59.400sp|Q9NX52|RHBL2_HUMAN Rhomboid-related protein 2 OS=Homo sapiens GN=RHBDL2 PE=1 SV=2  ali follow..  20  37.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................KDRAKSKKVHRIVSKWMLPEKSRGTYLERANCFPPPVFIISISLAELAVFI---YYAVWKPQKQWITLDTGILESPFYSPEKREEAWRFISYMLVHAGVQHILGNLCMQLVLGIPLEMVHKGLRVGLVYLAGVIAGSLASSIFDPLRYLVGASGGVYALMGGYFMNVLVNFQEMIPAFGIFRLLIIILIIVLDMGFASPVSFAAHIAGGFAGMSIGYTVFSCFDKALLKDPRFW--IAIAAYLACVLFAVFFNIFLSPAN............................ 303
10 -52.000sp|P58872|RHBL3_HUMAN Rhomboid-related protein 3 OS=Homo sapiens GN=RHBDL3 PE=2 SV=1  ali follow..  19  145........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................PREIDRKWYYDSYTCCPPPWFMITVTLLEVAFFLY-NGVSLGQFVLQVTHPRYLKNSL-VYHPQLRAQVWRYLTYIFMHAGIEHLGLNVVLQLLVGVPLEMVHGATRIGLVYVAGVVAGSLAVSVADMTAPVVGSSGGVYALVSAHLANIVMNWSGMKCQFKLLRMAVALICMSMEFGRAPHPSFVAHLGGVAVGITLGVVVLRNYEQRLQDQSLWWIFVAMYTVFVLFAVFWNIFAY................................. 393
11 -51.300sp|O75783|RHBL1_HUMAN Rhomboid-related protein 1 OS=Homo sapiens GN=RHBDL1 PE=2 SV=1  ali follow..  16  179........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................PCEVDRRWYFYRHRSCPPPVFMASVTLAQIIVFLC-YGARLNKWVLQTYHPEYMKSPL-VYHPGHRARAWRFLTYMFMHVGLEQLGFNALLQLMIGVPLEMVHGLLRISLLYLAGVLAGSLTVSITDMRAPVVGGSGGVYALCSAHLANVVMNWAGMRCPYKLLRMVLALVCMSSEVGRAPQPSFMAHLAGAVVGVSMGLTILRSYEERLRDQCGWWVVLLAYGTFLLFAVFWNVFAY................................. 427
12 -51.100sp|Q6PJF5|RHDF2_HUMAN Rhomboid family member 2 OS=Homo sapiens GN=RHBDF2 PE=1 SV=2  ali   49  1................................................................................................................YGRLKASCQRDLELPSQEAPSFQGTESPKPCK-------MPKIVDPLARGRAFRHPEEM-DRPHAPHPPLTPGVLSLTSFTSVRSGYSHLP-RRKRMSVAHMSLQAAAALLKGRSVLDAQRCRVVKRSFAFPSFLEEDVVDGADTFDSSFFSKEEMSSMPDDVFESPPLSASYFRGIP----------------------------------HSASPVSPDGVQIPLKEYGRAPVPGPRRGKRIASKVHFAFDRKKRHYGLGVVGNWLNRSYRRSISSTVQRQLESFDSHRPYFTYWLTFVHVIITLLVICTYGIAPVGFAQHVTTQLVLRNKGVYESVK................................................................................................................................................................................................................................................................................................................................................................................................................... 300
13 -46.400sp|Q6PJF5|RHDF2_HUMAN Rhomboid family member 2 OS=Homo sapiens GN=RHBDF2 PE=1 SV=2  ali   44  1MASADSVSSSRLQSRKPPNLSITIPPPEKETQAPGEQDSMLPEGFQNRRLKKSQQEPRSRWQESSEKRPGFRRQASLSQSIRKGAAQWFGVSGDWEQRQQWQRRSLHHCSMRYGRLKASCQRDLELPSQEAPSFQGTESPKPC-------KMPKIVDPLARGRAFRHPEEM-DRPHAPHPPLTPGVLSLTSFTSVRSGYSH-LPRRKRMSVAHMSLQAAAALLKGRSVLDAQRCRVVKRSFAFPSFLEEDVVDGADTFDSSFFSKEEMS.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 300
14 -36.100sp|Q8TEB9|RHBD1_HUMAN Rhomboid domain-containing protein 1 OS=Homo sapiens GN=RHBDD1 PE=2 SV=1  ali follow..  15  23.........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................GINNIPPVTLATLALNIWFFLNPQKPLYS----------CLSVEKCYQQKDWQRLLLSPLHHADDWHLYFNMASMLWKGINLERRLGSRWFAYVITAFSVLTGVVYLLLQFRSCAVGFSGVLFALKVLNNHYCPGGFVNILGFPVPNRFACWVELVAIHL-FSPGTSFAGHLAGILVGLMYTQGPLKKIM................................................................ 214
15 -34.100sp|Q9H300|PARL_HUMAN Presenilins-associated rhomboid-like protein, mitochondrial OS=Homo sapiens GN=PARL PE=1 SV=2  ali follow..  17  199.....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................NPASKVLCSPMLLSTFSHFSLFHMAANMYVLWSFSSSIVNILGQEQFMAVYLSAGVISNFVSYVGKRYGPSLGASGAIMTVLAAVCTKIIIFLPMFTFTAGNALKAIIAMDTAGMILGWKFFDHAAHLGGALFGIWYVTYGHELIWKNREPLVKI....................................................... 363
16 -33.000sp|Q6NTF9|RHBD2_HUMAN Rhomboid domain-containing protein 2 OS=Homo sapiens GN=RHBDD2 PE=2 SV=2  ali follow..  13  24................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................TALLSLLVSGPRLFLLQQPLAPSGLTLK--------SEALRNWQVYRLVTYIFVYENPISLLCGAIIIWRFAGNFERTVGTVRHCFFTVIFAIFSAIIFLSFEEVEDARGFTPVAFAMLGVTTVRSRMRRALV----MVVPSVLVPWLLLGASWLIPQTSFLSNVCGLSIGLAYGLTYCYSIDLSE............................................................. 208
17 -29.300sp|Q9Y3P4|RHBD3_HUMAN(removed signalp:1-33) Rhomboid domain-containing protein 3 OS=Homo sapiens GN=RHBDD3 PE=2 SV=1  ali follow..  17  11......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................LLDPWQVHRLLTHALGHTALPGLLLSLLLLPTVGWQQECHLGTLRFLHASALLALASGLLAVLLASAAGSCGYMPVHLAMLAGEGHRPRRPRGALP------PWLSPWLLLALTPLLSSEPPFLQLLCGLLAGLAYAAGAFRWLEPSE............................................................. 157
18 -23.000sp|Q12893|TM115_HUMAN(removed signalp:1-46) Transmembrane protein 115 OS=Homo sapiens GN=TMEM115 PE=1 SV=1  ali follow..  16  12...........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................WIWTLATHGLMEQHVWDVAISLTTVVVAGRLLEPLWGALELLIFFSVVNVSVGLLGAFAY-TVRIHGALGFLGGVLVA-LKQTMGDCVVLRVPQVRVSVMPMLLLALLLLLRLATLLQSPALASYGFGLLSSWVYLRFYQRHSRGR.......................................................... 169
19 -21.500sp|Q8NBM4|UBAC2_HUMAN Ubiquitin-associated domain-containing protein 2 OS=Homo sapiens GN=UBAC2 PE=2 SV=1  ali follow..  11  15................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................LSKSLLLVPSALSLLLALLLPHCQKLF-----VYDLHAVKNDFQIWRLICGRIICLDLKDTFCSSLLIYNF-RIFERRYGSRKFASFLLGSWVLSALFDFLLI-SNLPSGFLAPVFALFVPFYCSIPRVQVAQILGPLSITNKTLIYILGLQLFTSGSYIWIVAISGLMSGLCYDSKMFQ................................................................... 199
20 -10.900sp|O95243|MBD4_HUMAN Methyl-CpG-binding domain protein 4 OS=Homo sapiens GN=MBD4 PE=1 SV=1  ali follow..  10  1MGTTGLESLSLGDRGAAPTVTSSVPDPPNDLRKEDVAMELERVGEDEEQMMIKRSSECNPLLQEPIASAQFGATAGTRVVKQRLFGKTAGVYFISPQGLKFRSKSKRGIKSRYKDCSMAALTSHLQNQSNNSNWNLRTRSKCKKDVFMPPSSSSELQESRGLSNFTSTHLLLKEDEGVDDVNFRKVRKPKGKVTILKGIPIKKTKKGCRKSCSGFVQSDSKRESVCNKADAESEPVAQKSQLDRTVCISDAGACGETLSVTSEENSLVKKKERSLSSGSNFCSEQKTSGIINKFCSAKDSEHNEKYEDTFLESEEIGTKVEVVERKEHLHTDILKRGSEMDNNCSPTRKDFTGEKIFQEDTIPRTQIERRKTSLYFSSKYNKEALSPPRRKAFKKVQETLFHDPWKLLIATIFMAIPVLWKFLE--LKPLGLYDLRAKTIVKFSDEYLTKQWKYPIELHGIGKYGNDSYRIFCEWKQVHPEDHKLNKYHDWLWENHEKLS................................................................................................................................................................................................................................................................................................................................................................... 578
21 -10.500sp|Q96RT7|GCP6_HUMAN Gamma-tubulin complex component 6 OS=Homo sapiens GN=TUBGCP6 PE=1 SV=3  ali   12  1...........................................................................ELERKARQALVDHYSLSAEAARREQWRIQRHRLESARLRFLLED-----------------------------EKHIQEMLKAVSEAHQPQEPPDVLLSVHPQVTSPGPEHPEGGQGCDSGSAEQHSPAWDGWNRPGLLTPQPLKPLAVGAGGRGLQQAEGARPFSDSLSIGDFLPVGPGAEPSVQTGMVPLLEVALQTINLDLPPSAPGEAPAAASTQPSRPQEYDFSTVLRPAVATSPAPGPLQAAECSLGSSGLQLWEDSCGKMDACGSASRETLLPSHPPRRAALEEGSSQPTERLFGQVSGGGLP------TGDYASEIAPTRP----W.............................................................................................................................................................................................................................................................................................................................................................................................................................................................. 300
22 -10.400sp|Q8NBW4|S38A9_HUMAN Putative sodium-coupled neutral amino acid transporter 9 OS=Homo sapiens GN=SLC38A9 PE=1 SV=2  ali follow..  9  1................................................................................................................................................................................................................................................MANMNSDSRHLGTSEVDHERDPGPMNIQFEPSDLRSKRPFCIEPTNIVNVNHVIQRVSDHASAMNKRIHYYSRLTTPADKALIAPDHVVPAPEECYVYSPLGSAYKLQSYTEGYGKNTSLVTIFMIWNTMMGTSILS--------------------------PW---FTTGMCVIILMGLLTLYCCYRV-VKSRTMMFSLDTTSWEYPDVCRH------FGSFGQWSSLIGAMIVYWVLMSNFLFNTGKFIFNFIHHIN--DTDTILSTNNSNPVICPSAGSGGHPDNSSMIFYANDTGAQQFEKWW--------------------------------------DKSRTVPFYLVGLLLPLLNFKSPSFFSKFNILGTVSVLYLIFLVTFKAVRLGFHLEFHWFIPTEFFVPEIRFQFPQLTGVLTLAFFIHNCIILLKNNKKCIAYMLVTLTYLYIGVLVFASDCIEQNFLDNFPSSDTLSFIARIFLFQMMTVYPLLGYLARVILNLIIVGAGVIMACFYPNIGGIIRYSGAACGLAFVFIYLIYIISLHQEERLTWPKLIFHVFIIILGVANLIVQFFM............................... 561
23 -10.100sp|Q96Q80|DERL3_HUMAN Derlin-3 OS=Homo sapiens GN=DERL3 PE=1 SV=2  ali follow..  17  10..........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................FLQVPAVTRAYTAACVLTTAAVQLELLSPFQLYFN------PHLVFRKFQVWRLVTNFLFFGPLFSFFFNMLFVFRYCRMLEEGSFRGRFVFMFLFGGVLMTLLGLLG-----------SLFFLGQALMAMLVYVWSRRSPRVRVNFFGLLTFWALMGFSLLLGNSILVDLLGIAVGHIYYFL...................................................................... 185
24 -10.100sp|O43688|LPP2_HUMAN(removed signalp:1-30) Lipid phosphate phosphohydrolase 2 OS=Homo sapiens GN=PPAP2C PE=1 SV=1  ali follow..  15  65.....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................VYKVLGTFLFGAAVSQSLTDLAKYMIGRLRPNFLYVQLEKVCRGNPADVTEARLSFYSGHSSFGMYCMVFLALYVQARLCWKWARLLRPTVFLVAFALYVGYTRVSDYKHHLVGLLQGALVAALTV.................................................................... 210
25 -9.990sp|Q8NBD8|T229B_HUMAN Transmembrane protein 229B OS=Homo sapiens GN=TMEM229B PE=2 SV=1  ali follow..  12  4..............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................AEPLTALSRWYLYAIHGYFCEVMFTAAWEFVGTSVWALFIYGTSILIVERMYLRLRGRCPLLLRCLIYTLWTYLWEFTTGFQFDFDFMGLIGALIMEQFIIRNTLRLRFDKDAEPGEPSGALALANGHVKT...................................... 166
26 -9.970sp|Q86TG1|T150A_HUMAN(removed signalp:1-24) Transmembrane protein 150A OS=Homo sapiens GN=TMEM150A PE=2 SV=1  ali follow..  13  1..............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................MAVMNHHVCPVENWSYNESCPPDPAEQGGPKTCCTLDDV--PLISKCGPESCLFSFMVALICLLRYGQLLEQSRHSWVNTTALITGCTNAAGLL--VGNFLHYVGAGVAFPAGLLLSYQGATAPLDLAVAYLRSVLAVIAFITLVLSGVFQLQHGAALCEWVCVIDILIFYGTFSYEFG...... 206
27 -9.900sp|P35575|G6PC_HUMAN Glucose-6-phosphatase OS=Homo sapiens GN=G6PC PE=1 SV=2  ali follow..  16  27..........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................QDWFILVSVI----ADLRNAFYVLFPIWF---LQEAVG-IKLLWVAVIGDWLNLVFKWILFPYTCETGPSGGVYYVMVTSTLSIFQGKIKPTYRFRCLNVILWLGFWAVQLNVLSRIYLAAHVAGVLSGIAVAETFSHIHSIYNASLKKYFLITFFLFSFAIGFYLLLKGLGVDLL----------TLEKAQRWCEQPE...... 249
28 -9.840sp|O14494|LPP1_HUMAN(removed signalp:1-27) Lipid phosphate phosphohydrolase 1 OS=Homo sapiens GN=PPAP2A PE=1 SV=1  ali follow..  17  71.....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................IYKAIGTFLFGAAASQSLTDIAKYSIGRLRPHFLGYIEYYICRGNAERVKEGRLSFYSGHSSFSMYCMLFVALYLQARMKGDWARLLRPTLGLVAVSIYVGLSRVSDYKHHLTGLIQGALVAILVAVYV................................................................. 219
29 -9.820sp|B9EJG8|T150C_HUMAN(removed signalp:1-22) Transmembrane protein 150C OS=Homo sapiens GN=TMEM150C PE=2 SV=1  ali follow..  14  1........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................GLWIVYF---------------IAVEDDKILPLNSAERKPGVKHA--PYISIAGPASCVFSFLALVVAVLRFIQLKPKVLNPWLNISGLVALCLASFGMT--LGNFIHNVGTSLTFGFGTLTVNIKNEGRRVGIPRVILSASITLCVVLYFILMAQSIHMYAARVQWGLVMCFLSYFGTFAVEFR...... 194
30 -9.680sp|Q8NEB5|PPC1B_HUMAN(removed signalp:1-27) Phosphatidate phosphatase PPAPDC1B OS=Homo sapiens GN=PPAPDC1B PE=1 SV=2  ali follow..  15  59.....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................SRQACLAASLALALNGVFTNTIKLIVGRPRFFYRCFPDGLAHSDLMCTGDKDVVNEGPSGSSFAFAGLAFASFYLAGKL-RGKSWRFCAFLSPLLFAAVIALSRTCDYKHHWQDVLVGSMIGMTFA.................................................................... 197
31 -9.660sp|Q8TBC5|ZSC18_HUMAN Zinc finger and SCAN domain-containing protein 18 OS=Homo sapiens GN=ZSCAN18 PE=2 SV=2  ali follow..  10  8FASPRSSPAPPDLPTPGSAAGVQQEEPETIPERTPADLEFSRREFVYQEAAGPHQTLARLHE-RQWLMPEARSKEQMLELL---LEQFLGI----DKVRPWVVAQYPESCKKAASLVEGLADVLEEPGMLLGSPAGSSSILSDGVYERHMDPLLLPGELASPSQALGAGEIPAPSETPWLSPDPLFLEQRRVREAKTEEDGPANTEQK----LKSFPEDPQHLGEWGHLDPAEENLKSYRKLLLWGYQLSQPDAASRLDTEELRLVERDPQGSSLPEGGRRQESAGCACEEAAPAGVLPELPTEAPPGDALADPPSGTTEEEEEQPGKAPDPQDPQDAESDSATGSQRQSVIQQPAPDRGTAKLGTKRPHPE----VSSSGDSAGLEAGQGPGADEPGLSRGKPY----------------------GECGEAFAWLSHLMEHHS-----------------------SHGGRKYA-CWKTFHFSLALAEHQKEKEKSYALG----------------------------GARGPQPSTREAQAGARAGGPPESVEG.......................................................................................................................................................................................................................................................................................................... 499
32 -9.530sp|Q5VZY2|PPC1A_HUMAN(removed signalp:1-21) Phosphatidate phosphatase PPAPDC1A OS=Homo sapiens GN=PPAPDC1A PE=1 SV=2  ali follow..  13  59.....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................IKEAFLAVSLALALNGVCTNTIKLIVGRPRFFYRCFPDGVMNSEMHCTGDPDLVSEGPSISSFAFSGLGFTTFYLAGKL-RGKSWRLCAAILPLYCAMMIALSRMCDYKHHFVGGVIGLIFAYICY.................................................................... 201
33 -9.470sp|Q9BUM1|G6PC3_HUMAN Glucose-6-phosphatase 3 OS=Homo sapiens GN=G6PC3 PE=1 SV=2  ali follow..  12  23..........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ENVWLWITFL----GDPKILFLFYFPAAY---ASRRVG-IAVLWISLITEWLNLIFKWFLFPSSCETGPSGAALWPIMTALSSQVATRARSRWVRVMPSLAYCTFLLAVGLSRI------AHLAGLITGAVLGWLMTPRVPMERELSFYGLTALALMLGTSLIYWTLFT.................................... 219
34 -9.430sp|Q9NQR9|G6PC2_HUMAN Glucose-6-phosphatase 2 OS=Homo sapiens GN=G6PC2 PE=1 SV=1  ali follow..  13  23..........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................YTFLNFMSNV----GDPRNIFFIYFPLCFQ--FNQTVG-TKMIWVAVIGDWLNLIFKWILFPYETGPGPSGCVWYVMVTAALSHTVCGMDKFSITLHRLTWSFLWSVFWLIQISVCISRVTHILGVIGGMLVAEAFEHTPGIQTASLGTYLKTNLFLFLFAVGFYLLLRVLNIDLLWS---------VPIAKKWCANPD...... 247
35 -9.410sp|Q7Z2D5|LPPR4_HUMAN Lipid phosphate phosphatase-related protein type 4 OS=Homo sapiens GN=LPPR4 PE=1 SV=1  ali   9  25.....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................AVRFVGVHVFGLCSTALITDIIQLSTGYQAPYFLYIVEDICSGSDLTVINSGRKSFPSQHATLAAFAAVYVSMYFNSTLDSSKLLKPLLVFTFIICGIICGLTRITQYKNHYCGFLIGGGIALYLG.................................................................... 173
36 -9.210sp|Q9Y5U4|INSI2_HUMAN Insulin-induced gene 2 protein OS=Homo sapiens GN=INSIG2 PE=1 SV=2  ali follow..  14  31..................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................RGVVLFFIGVFLALVLNLLQIQRNVTLGTASAVIGLLYPCIDRHLGEPHKFKREWSSVMRVAVFVGINHASAKVDFDNNWWTFDRSRSGFGLGVGIA------------------FLATVVTQLLVYNGVYQYTSPDFLYVRSWLPCIFFAGGIT.......... 202
37 -9.180sp|Q6UX65|DRAM2_HUMAN DNA damage-regulated autophagy modulator protein 2 OS=Homo sapiens GN=DRAM2 PE=1 SV=1  ali follow..  14  2...................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................WWFQQGLSFLPSALVIWTSAA-----------FIFSYITAVTLHHIDPAL--PYISDTGPEKCLFGAIAAVLCIAVHALSPEENVIIKLNKAGLVLGILSCLGLS--VANFAHVSGFGMGSLVQTILSYQMQPKIHGKQVFWIRLLLVIWCGVSALSMLTCVLHMITTAAEWSMSFSFFGFFLTYIRDFQ...... 231
38 -9.160sp|Q32ZL2|LPPR5_HUMAN(removed signalp:1-27) Lipid phosphate phosphatase-related protein type 5 OS=Homo sapiens GN=LPPR5 PE=2 SV=2  ali follow..  11  92.....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................TVRFLGIYTFGLFATDIFVNAGQVVTGNLAPHFLFISGEEACTGNPDLIMRARKTFPSKEAALSVYAAMYLTMYITNTIKAKGTRLAKPVLCLMCLAFLTGLNRVAEYRNHIAGFLVGISIAVFLV.................................................................... 240
39 -9.080sp|A6NJY1|NHCL1_HUMAN Putative protein NHEDC1-like 1 OS=Homo sapiens PE=5 SV=3  ali follow..  9  1...................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................MVLQENGYGVEEDIPTLLMAASSMDDLLAITGFNTCLIVFYSGGMINNAIASLRNVCIS---LLAGIVLGFFVRYFPSEDQKKITLKRGFLVLITFVSAVLGSQPIGLHGSGGLCTLVLHFIEWGLVGAEVSVSLLESNIVGISVSTLSLALCVRILNIYLLMCFAGFSFKEKIFIALA-----WMPKATVQVRTY 215
40 -9.020sp|O14495|LPP3_HUMAN Lipid phosphate phosphohydrolase 3 OS=Homo sapiens GN=PPAP2B PE=1 SV=1  ali follow..  15  126.....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................LYKQVGCFLFGCAISQSFTDIAKVSIGRLRPHFLGYIQNYRCRGDDSKVQEARKSFFSGHASFSMYTMLYLVLYLQARFTWRGARLLRPLLQFIMMAFYTGLSRVSDHKHHLAGFAQGALVACCIV.................................................................... 271
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Ye Y, Godzik A. Multiple flexible structure alignment using partial order graphs. Bioinformatics. 2005 Mar 3;