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Query: [M] KOG2388 UDP-N-acetylglucosamine pyrophosphorylase, from COG1018

Results of FFAS03 search in H.sapiens
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MASTVDSNFFSSVPALHSNLGLLSPDQIELAKILLENGQSHLFQQWPELGVDDKEKLAFFDQIARLNSSYPGGLAAYIKTAKELLADSKVGKNPYDGFSPSVPSGENLTFGTDNFIEMEKRGVVEARNAAFVLVAGGLGERLGYNGIKVALPRETTTGTCFLQHYIESILALQEASNKIDSDGSERDIPFIIMTSDDTHSRTLDLLELNSYFGMKPTQVHLLKQEKVACLDDNDARLALDPHNKYSIQIQMDFSSMLVAATQLLCLKVFIQFLMEIHNSLMTSLVQAIPASLGVSATKQYHVNSLAVPRKAKEAIGGISKLTHVDGRSMVINVEYNQLDPLLRASGFPDGDVNCETGFSPFPGNINQLILELGPYKDELQKTGGAIKEFVNPKYKDSTKTAFKSSTRLECMMQDYPKTLPPTARVGFTVMDIWLAYAPVKNNPEDAAKVPKGNPYHSATSGEMAIYRANSLILQKAGVKVEEPVKQVLNGQEVEVWSRITWKPKWGMIFSDIKKKVSGNCEVSQRSTMAIKGRNVFIKDLSLDGALIVDSIDDAEVKLGGLIKNNGWTMESVDYKDTSVPEEIRIRGFRFNKVEQLEKKLTQPGKFSVEDLast
1 -105.000sp|Q16222|UAP1_HUMAN UDP-N-acetylhexosamine pyrophosphorylase OS=Homo sapiens GN=UAP1 PE=1 SV=3  ali follow..  18  2.........................NINDLKLTLSKAGQEHLLRFWNELEEAQQVE--LYAELQAMNFEELNFFFQKAIEGFNQSSHQKNVDARMEPVPREVLGSATRDQDQLQAWESEGLFQISQNKVAVLLLAGGQGTRLGVAYPKGMYDVGLPSRKTLFQIQAERILKLQQVAEKYYGNK--CIIPWYIMTSGRTMESTKEFFTKHKYFGLKKENVIFFQQGMLPAM-SFDGKIILEEKNKVSMAPDGNGGLYRALAAQNIVEDMEQRGIWSIHVYCVDNVKVADPRFIGFCIQKGADCGAKVVEKTNPTEPVGVVCRVD----GVYQVVEYSEISLATAQ------KRSSDGRLLFNAGNIANHFFTVPFLRDVVNVYEPQLQHHVAQKKIDTQGQLIKPDKPNGIKMEKFVDIFQFAKKFVVYEVLREDEFSPLKNA-------DSQNGKDNPTTARHALMSLHHCWVLNAGGHFIDENGSRLPAIPRSAGKSETITADVNHNLKDANDVPIQ-CEISPLISYAGEGLESYVADKEFHAPLIIDENGVHELVKNGI................................................. 522
2 -94.800sp|Q3KQV9|UAP1L_HUMAN UDP-N-acetylhexosamine pyrophosphorylase-like protein 1 OS=Homo sapiens GN=UAP1L1 PE=2 SV=2  ali follow..  16  2........................ASEQDVRARLQRAGQEHLLRFWAELAPEPRAA--LLAELALLEPEALREHCRRAAEACARPHGPPPDLAARLRPLPRVGRASRSDPETRRRWEEEGFRQISLNKVAVLLLAGGQGTRLGVTYPKGMYRVGLPSRKTLYQLQAERIRRVEQLAGERHGTR--CTVPWYVMTSEFTLGPTAEFFREHNFFHLDPANVVMFEQRLLPAV-TFDGKVILERKDKVAMAPDGNGGLYCALEDHKILEDMERRGVEFVHVYCVDNVRLADPVFIGFCVLQGADCGAKVVEKAYPEEPVGVVCQVD----GVPQVVEYSEISPETAQLRASDGSL------LYNAGNICNHFFTRGFLKAVTREFEPLLKPHVAVKKVNLVKPLKPNGIKMEKFVFDVFRFA---KNFAALEVLREEEFSPLKN--------AEPADRDSPRTARQALLTQHYRWALRAGARFLDAHGAWLPELP----------------SLPPNGDPPAICEISPLVSYSGEGLEVYLQGREFQSPLILDEDQAREPQLQ................................................... 505
3 -85.600sp|Q16851|UGPA_HUMAN UTP--glucose-1-phosphate uridylyltransferase OS=Homo sapiens GN=UGP2 PE=1 SV=5  ali follow..  13  3...........................RFVQDLSKAMSQDGASQFQEVIRQELELKKELEKILTTASSHEFEHTKKDLDGFRKLFHRFLQEKGPSVDWGKIPPEDSIQPYEKIKARGLPDNISSVLNKLVVVKLNGGLGTSMGCKGPKSLIGVR--NENTFLDLTVQQIEHLNKTYN--------TDVPLVLMNSFNTDEDTKKILQKYNHCRV---KIYTFNQSRYPRINKESKDVSYSGENTEAWYPPGHGDIYASFYNSGLLDGKEYIFVSNIDNLGATVDLYILNHLMNPPNGKRCEFVMEVTNKTRADVKGGTLTQYE----GKLRLVEIAQVPKAHVD--------EFKSVSKFKIFNTNNLWISLAAVKRLQEQNAIDMEIIVNAKTLDGG----LNVIQLETAVGAAIKSFE---NSLGINVPR-SRFLPVKTTSDLLLVMSNLYSLN--------------------------AGSLTMSEKREFPTVPLVKLGSSFTKVQDYLRRFESIPDMLELDHLTVSGDVTFGKNVSLKGTVIIIANHGDRIDIGAVLENKIVS.......................................... 500
4 -11.700sp|Q96IJ6|GMPPA_HUMAN Mannose-1-phosphate guanyltransferase alpha OS=Homo sapiens GN=GMPPA PE=1 SV=1  ali follow..  12  2................................................................................................................................LKAVILIGGKGTRLSFEVPKPLFPV---AGVPMIQHHIEACAQVP-------------GMQEILLIGFYQPDEPLTQFLEAA-FNL---PVRYLQEFA----------------------PLGTGGGLYHFRDQILAGSPEAFFVLNADVCSDFPLS----AMLEAHRRQRHPLLGTTANRTQSLNYGCIVENPQTH-----EVLHYVEKPSTFISDII----------------NCGIYLFSPEALKPL---------------------RDVFQRNQQDGQLEDSPGLWPGAGTIRL----EQDVFSALAGQGQIYVHLTDGIWSQIKSA--GSALYASRLYLSRYQDTHPERLAKHTPG----------------------GPWIRGNVYIHPTAKVVLGPNVSIGKGVTVGEGVRL---RESIVLHGATLQEHTCVLHSIVGWGSTVGRWARVEGTPSDPNPNDPRARMDSESLFKDG 378
5 -8.390sp|Q9NR50|EI2BG_HUMAN Translation initiation factor eIF-2B subunit gamma OS=Homo sapiens GN=EIF2B3 PE=1 SV=1  ali follow..  9  2...............................................................................................................................EFQAVVMAVGGGSRM-SSIPKPLLPV---GNKPLIWYPLNLLE--------------RVGFEEVIVVTTRDVQKALCAEFKMKM----KPDIVCIPDDA----------------------DMGTADSLRYIYPK-VLSCDLITDVALHEVVDLFRAYDASLAMLMRKGQDSIEPVPGQKGKKKAVEQRDFIGVDSTGKR-KGSILQKHPRIRFHTGLVDAHLYCLKKYIVDFLMENGSITSIRSELIPYLVRKQFSSASSQQGQEEKEEDLKKKELKSLDIYSFIKEANTLNLAPYDACWNACRGDRWEDLSRSQVRCYVHIMKEGLCSRVSTLGLYMEANRQVPKLLSALCPESSAQIVSKHLVGVDSLIGPETQIGEKSSIKRSVIGSSCLIKDRVTILLMNSVTVEEGSNIQGSVI----NNAVIEKGADIKDCLIGSGQRIEAKAKRVNEVIVGNDQLME.................. 451
6 -8.190sp|Q9Y5P6|GMPPB_HUMAN Mannose-1-phosphate guanyltransferase beta OS=Homo sapiens GN=GMPPB PE=1 SV=2  ali follow..  11  1................................................................................................................................MKALILVGGYGTRLTLSTPKPLVDF---CNKPILLHQVEALA--------------AAGVDHVILAVSYMSQVLEKEMKAQE-LGI---RISMSHEEE----------------------PLGTAGPLALARDLLSETADPFFVLNSDVICDFPFQAMVQ------FHRHHGQEGSILVTKVEEPSKYGVVVCEADTGR----IHRFVEKPQVFVSNKI----------------NAGMYILSPAVLQRIQLQPTSI----------------------------------------------EKEVFPIMAKEGQLYAMELQGFWMDIGQP--KDFLTGMCLFLQSLRQKQPERLCS--------------------------GPGIVGNVLVDPSARISIGPNVSLGPGVVVEDGVCI---RRCTVLRDARIRSHSWLESCIVGWRCRVGQWVRMENVTVLGEDVI.............. 331
7 -7.570sp|A4D126|ISPD_HUMAN 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase-like protein OS=Homo sapiens GN=ISPD PE=3 SV=2  ali follow..  9  45..............................................................................................................................QAVAAVLPAGGCGERMGVPTPKQFCPI---LERPLISYTLQALERVCWIKD------------IVVAVTGENMEVMKSIIQKYQH-GVTRHRLKALAEDQINSKLSKPEVVIIHD----AVRPFVEEGVLLKVVTAAKEHGAAGAIRPLVSTVVSPSADGCLDYSLERASEMPQAFLFDVIYEAYQQCSDYDLEFGTECLQ---LALKYCCTKAKLVEGSPDLWKVTYKR--------------DLYAAESIIKER.................................................................................................................................................................................................................................... 280
8 -7.150sp|Q96P26|5NT1B_HUMAN Cytosolic 5`-nucleotidase 1B OS=Homo sapiens GN=NT5C1B PE=2 SV=2  ali   15  2.......................................................................................................AKDMAYCDTQLRVAFDGDAVLFSDESEHFTKEHGLDKFFQYDTLCESKPLAQGPLKGFL----EDLGRLQKKFYAK-NERLLCPIRTYLVTARSAASSGARVLKTLRRWGLEIDEALFLAAPKSPILVKIRPHIFFDDHMF.............................................................................................................................................................................................................................................................................................................................................................................. 138
9 -7.090sp|Q13144|EI2BE_HUMAN Translation initiation factor eIF-2B subunit epsilon OS=Homo sapiens GN=EIF2B5 PE=1 SV=3  ali   12  18.......................................................................................................KRSGAGPGGSGGGGARGAEEEPPPPLQAVLVADSFDRRISKDQPRVLLPL---ANVALIDYTLEFLTA--------------TGVQETFVFCCWKAAQIKEHLLKSKW............................................................................................................................................................................................................................................................................................................................................................................................................... 111
10 -6.100sp|Q86WS4|CL040_HUMAN Uncharacterized protein C12orf40 OS=Homo sapiens GN=C12orf40 PE=2 SV=3  ali   9  4......................................................................................................................................VGGSRSRVLIKQER-------RKQKEYFE-LKSKMKSLGVLSPVKNSAVSLDILNLYMVNQISCKKKIPETVRKPTHVNMNRDIKMPLRKHNLPHCVPSKLCL..................................................................................................................................................................................................................................................................................................................................................................................... 106
FFAS is supported by the NIH grant R01-GM087218-01
1 4 7 9 3 8   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Li W, Godzik A. cd-hit: a fast program for clustering and comparing large sets of protein or nucleotide sequences. Bioinformatics. 2006 May 26;