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Query: [I] KOG3146 Dolichyl pyrophosphate phosphatase and related acid phosphatases, from COG1018

Results of FFAS03 search in H.sapiens
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MDLIPQQLKAVTLTHVRYRPGDQLGHFLAWISLVPVFISLGGFVSHFLFRRELQGIFFGIGLVISQFINEFIKTSVEQARPETCTLLEACDSHGWPSSHSQFMFFFATYFSLMGCKGIGFWFGLRSRWIMNLLHWSLAVVTMYSRVYLGYHTVAQVFAGAALGGIVGASWFWVVNSVLYPFFPVIEESVLGRWLYVKDTSHIPDVLKFEYDNARAARKDMDSAKSDLast
1 -92.600sp|Q86YN1|DOPP1_HUMAN Dolichyldiphosphatase 1 OS=Homo sapiens GN=DOLPP1 PE=1 SV=1  ali follow..  37  7.CSLPASWRPVTLTHVEYPAGDLSGHLLAYLSLSP-VFVIVGFVTLIIFKRELHTISFLGGLALNEGVNWLIKNVIQEPRPCGGPHTAVGTKYGMPSSHSQFMWFFSVYSFLFLYLRMARFLDLLWRHVLSLGLLAVAFLVSYSRVYLLYHTWSQVLYGGIAGGLMAIAWFIFTQEVLTPLFPRIAAWPVSEFFLIRDTSLIPNVLWFEYTVTRAEARNRQRKLGT 235
2 -53.500sp|Q8NBV4|PPAC3_HUMAN Probable lipid phosphate phosphatase PPAPDC3 OS=Homo sapiens GN=PPAPDC3 PE=2 SV=1  ali follow..  12  85LLAIDICMSKCAGRAASWASARSMVKLIGITGHGIPWIGGTILCLVKSSTLAGQLMNLLLALLLDIMTVAGVQKLIKRRGPPSLLDYLTMDIYAFPAGHASRAAMVSKFFLSHLVL----------AVPLRVLLVLWALCVGLSRVMIGRHHVTDVLSGFVIGYLQFRLVELVW.................................................... 258
3 -51.200sp|Q8IY26|PPAC2_HUMAN Presqualene diphosphate phosphatase OS=Homo sapiens GN=PPAPDC2 PE=1 SV=3  ali follow..  16  106LLAIDLWLSVCAGESSSWGSVRPLMKLLEISGHGIPWLLGTLYCLCRSDSWAGRLMNLLFALLLDLLLVALIKGLVRRRRPMDMFVTLSVDKYSFPSGHATRAALMSRFILNHLVL----------AIPLRVLVVLWAFVLGLSRVMLGRHNVTDVAFGFFLGYMQYSIVDYCWLSPHNA.............................................. 285
4 -47.900sp|Q8IWX5|SGPP2_HUMAN Sphingosine-1-phosphate phosphatase 2 OS=Homo sapiens GN=SGPP2 PE=2 SV=1  ali follow..  15  66LRRAAAPEAYVQKYVVKNYFYYYLFQFSAALGQEVFYITFLPFTHWNIDPY--LSRRLIIIWVLVMYIGQVAKDVLKWPRPVVKLEKRLIAEYGMPSTHAMAATAIAFTLLISTMDRYQYP-----FVLGLVMAVVFSTLVCLSRLYTGMHTVLDVLGGVLITALLIVLTYPAWTFI................................................. 239
5 -47.700sp|Q9BX95|SGPP1_HUMAN Sphingosine-1-phosphate phosphatase 1 OS=Homo sapiens GN=SGPP1 PE=1 SV=2  ali follow..  14  109RRNSLTGEEGQ-LARVSNWPLYCLFCFGTELGNELFYILFFPFWIWNLDPL--VGRRLVVIWVLVMYLGQCTKDIIRWPRPASPPEVFYNSEYSMPSTHAMSGTAIPISMVLLTYGRWQYP-----LIYGLILIPCWCSLVCLSRIYMGMHSILDIIAGFLYTILILAVFYPFVDLIDNFNQTHKYAPFIIIGLHL.............................. 300
6 -47.500sp|Q9BUM1|G6PC3_HUMAN Glucose-6-phosphatase 3 OS=Homo sapiens GN=G6PC3 PE=1 SV=2  ali follow..  14  1MESTGAGIVIAEALQNQLAWLENVWLWITFLGDPKILFLFYFPAAYYASRR--VGIAVLWISLITEWLNLIFKWFLFGDRPVHQFPSSCETGPGSPSGHCMITGAALWPIMTALSSQVATRASRWVRVMPSLAYCTFLLAVGLSRIFILAHFPHQVLAGLITGAVLGWLMTPRVPMERE............................................... 195
7 -47.000sp|Q9NQR9|G6PC2_HUMAN Glucose-6-phosphatase 2 OS=Homo sapiens GN=G6PC2 PE=1 SV=1  ali follow..  13  1MDFLRNGVLIIQHLQKDYRAYYTFLNFMSNVGDPRNIFFIYFPLCFQFNQT--VGTKMIWVAVIGDWLNLIFKWILFGHRPLEQFPTTCETGPGSPSGHAMGASCVWYVMVTAALSHTSITLHRLTWSFLWSVFWLIQISVCISRVFIATHFPHQVILGVIGGMLVAEAFEHTPGIQTASLGTYLKTNLFLFLFAV.............................. 219
8 -46.900sp|P35575|G6PC_HUMAN Glucose-6-phosphatase OS=Homo sapiens GN=G6PC PE=1 SV=2  ali follow..  15  1MEEGMNVLHDFGIQSTNYQDSQDWFILVSVIADLRNAFYVLFPIWFHLQEA--VGIKLLWVAVIGDWLNLVFKWILFGQRPIKQFPVTCETGPGSPSGHAMGTAGVYYVMVTSTLSIFQGKRFRCLNVILWLGFWAVQLNVCLSRIYLAAHFPHQVVAGVLSGIAVAETFSHIHSIYNASLKKYFLITFFLFSFAI.............................. 221
9 -37.100sp|Q8NEB5|PPC1B_HUMAN(removed signalp:1-27) Phosphatidate phosphatase PPAPDC1B OS=Homo sapiens GN=PPAPDC1B PE=1 SV=2  ali follow..  14  3LPPFQRLIQPEEMWLYRNPYVEAEYFPTKPMFVIAFLSPLSLIFLAKFLKKAQACLAASLALALNGVFTNTIKLIVGRPRPDFFYRVVNEGRKSFPSGHSSFAFAGLAFASFYLAGKLHQGRGKSWRFCAFLSPLLFAAVIALSRTCDYKHHWQDVLVGSMIGMTFAYVCYRQY.................................................... 204
10 -36.800sp|Q5VZY2|PPC1A_HUMAN(removed signalp:1-21) Phosphatidate phosphatase PPAPDC1A OS=Homo sapiens GN=PPAPDC1A PE=1 SV=2  ali follow..  15  3LDPFQRVIQPEEIWLYKNPLVQSDNIPTRLMFAISFLTPLAVICVVKIIRRTEAFLAVSLALALNGVCTNTIKLIVGRPRPDFFYRCFPDGVMSFPSIHSSFAFSGLGFTTFYLAGKLHSGRGKSWRLCAAILPLYCAMMIALSRMCDYKHHWQDSFVGGVIGLIFAYICYRQH.................................................... 204
11 -36.700sp|O14494|LPP1_HUMAN(removed signalp:1-27) Lipid phosphate phosphohydrolase 1 OS=Homo sapiens GN=PPAP2A PE=1 SV=1  ali follow..  17  16.............ESIKYPYKEDTIALLGGIIIPFSIIVIILGETLSVYCNLLHIGTFLFGAAASQSLTDIAKYSIGRLRPRGNAERVKEGRLSFYSGHSSFSMYCMLFVALYLQARMKGDWARLLRPTLQFGLVAVSIYVGLSRVSDYKHHWSDVLTGLIQGALVAILVAVYV.................................................... 219
12 -36.600sp|Q32ZL2|LPPR5_HUMAN(removed signalp:1-27) Lipid phosphate phosphatase-related protein type 5 OS=Homo sapiens GN=LPPR5 PE=2 SV=2  ali follow..  13  20....DSAYRKPYPGPEDSSAVPPVLLYSLAAGVPVLVIIVGETAVFCLQLATRDLGIYTFGLFATDIFVNAGQVVTGNLAPTGNPDLIMRARKTFPSKEAALSVYAAMYLTMYITNTIKAKGTRLAKPVLCLGLMCLAFLTGLNRVAEYRNHWSDVIAGFLVGISIAVFLVVCV.................................................... 243
13 -36.500sp|Q8TBJ4|LPPR1_HUMAN(removed signalp:1-31) Lipid phosphate phosphatase-related protein type 1 OS=Homo sapiens GN=LPPR1 PE=2 SV=1  ali follow..  15  21....DGDLMKPYPGTEEESFITPLVLYCVLAATPTAIIFIGEISMYFIKSTRESTGVFAFGLFATDIFVNAGQVVTGHLTPTGDLEVIEKARRSFPSKHAALSIYSALYATMYITSTIKTKSSRLAKPVLCLGTLCTAFLTGLNRVSEYRNHCSDVIAGFILGTAVALFLGMCV.................................................... 244
14 -36.400sp|O43688|LPP2_HUMAN(removed signalp:1-30) Lipid phosphate phosphohydrolase 2 OS=Homo sapiens GN=PPAP2C PE=1 SV=1  ali follow..  17  11.............DSIRYPYRPDTITLMAGVTITATVILVSAGEAYLVYTDRLYLGTFLFGAAVSQSLTDLAKYMIGRLRPRGNPADVTEARLSFYSGHSSFGMYCMVFLALYVQARLCWKWARLLRPTVQFFLVAFALYVGYTRVSDYKHHWSDVLVGLLQGALVAALTVCYI.................................................... 213
15 -36.000sp|Q96GM1|LPPR2_HUMAN(removed signalp:1-41) Lipid phosphate phosphatase-related protein type 2 OS=Homo sapiens GN=LPPR2 PE=2 SV=1  ali follow..  12  12....DSTYAKPYPGPEAASRVPPALVYALVTAGPTLTILLGELARAFFPAPPSALGVYSFGLFTTTIFANAGQVVTGNPTPAGSPSLVAAARRAFPCKDAALCAYAVTYTAMYVTLVFRVKGSRLVKPSLCLALLCPAFLVGVVRVAEYRNHWSDVLAGFLTGAAIATFLVTCV.................................................... 243
16 -34.800sp|O14495|LPP3_HUMAN Lipid phosphate phosphohydrolase 3 OS=Homo sapiens GN=PPAP2B PE=1 SV=1  ali follow..  20  71.............ESIKYPLKTGETINDAVLCAVGIVIAILAIITGYVAALYKQVGCFLFGCAISQSFTDIAKVSIGRLRPRGDDSKVQEARKSFFSGHASFSMYTMLYLVLYLQARFTWRGARLLRPLLQFTLIMMAFYTGLSRVSDHKHHPSDVLAGFAQGALVACCIVFFV.................................................... 274
17 -32.600sp|Q6T4P5|LPPR3_HUMAN Lipid phosphate phosphatase-related protein type 3 OS=Homo sapiens GN=LPPR3 PE=2 SV=1  ali   17  126..............................................FLRRTVRFVGVHVFGLCATALVTDVIQLATGYHTPFHDIHAILSARKTFPSQHATLSAFAAVYVSMYFNSVISD-TTKLLKPILVFAFAIAAGVCGLTQITQYRSHPVDVYAGFLIGAGIAAYLACHA.................................................... 281
18 -32.400sp|Q7Z2D5|LPPR4_HUMAN Lipid phosphate phosphatase-related protein type 4 OS=Homo sapiens GN=LPPR4 PE=1 SV=1  ali   16  21..............................................FLRRAVRFVGVHVFGLCSTALITDIIQLSTGYQAPYSDLTVINSGRKSFPSQHATLAAFAAVYVSMYFNSTLTD-SSKLLKPLLVFTFIICGIICGLTRITQYKNHPVDVYCGFLIGGGIALYLGLYA.................................................... 176
19 -29.600sp|Q6T4P5|LPPR3_HUMAN Lipid phosphate phosphatase-related protein type 3 OS=Homo sapiens GN=LPPR3 PE=2 SV=1  ali   17  1.......................................................................IQLATGYHTPFHDIHAILSARKTFPSQHATLSAFAAVYVSMYFNSVISD-TTKLLKPILVFAFAIAAGVCGLTQITQYRSHPVDVYAGFLIGAGIAAYLACHA.................................................... 131
20 -24.600sp|Q7Z2D5|LPPR4_HUMAN Lipid phosphate phosphatase-related protein type 4 OS=Homo sapiens GN=LPPR4 PE=1 SV=1  ali   12  106.............RSLSMPYIEPTQEAIPFLMLLSLAFAGPAITIMVLRRAVRFVGVHVFGLCSTALITDIIQLSTGYQAPYSDLTVINSGRKSFPSQHATLAAFAAVYVSMYFNSTLTDS-SKLLKPLLVFTFIICGIICGLTRI................................................................................ 298
21 -15.500sp|Q8NHU3|SMS2_HUMAN Phosphatidylcholine:ceramide cholinephosphotransferase 2 OS=Homo sapiens GN=SGMS2 PE=1 SV=1  ali follow..  8  113............LPDKFFDYIDRVKWAFSVSEINGIILVGLWITQWLFLRYKSIVGRRFCFIIGTLYLYRCITMYVTTPVPGMHFQCAPKLNGDLFSGHTVTL-----TLTYLFIKEYSPRHFWWYHLICWLLSAAGIICILVAH----EHYTIDVIIAYYITTRLFWWYHSMANEKNTNFLSRAWWFPIFYFFEKNVQGSIPCCFSWPLKSSCKKYSRVQKIGED 360
22 -14.700sp|Q86VZ5|SMS1_HUMAN Phosphatidylcholine:ceramide cholinephosphotransferase 1 OS=Homo sapiens GN=SGMS1 PE=1 SV=2  ali follow..  8  175............LPDTFFDHFNRVQWAFSICEINGMILVGLWLIQWLLLKYKSIISRRFFCIVGTLYLYRCITMYVTTPVPGMHFNCSPKLFGDWESGHTVML-----TLTYLFIKEYSPRRLWWYHWICWLLSVVGIFCILLAH----DHYTVDVVVAYYITTRLFWWYHTMANQQVMNLLARVWWYRPFQYFEKNVQGIVPRSYHWPFVVHLSRQVKYSRLVND 418
23 -13.400sp|Q96LT4|SAMD8_HUMAN Sphingomyelin synthase-related protein 1 OS=Homo sapiens GN=SAMD8 PE=2 SV=2  ali follow..  7  186............LPDIFLDSVPRIPWAFAMTEVCGMILCYIWLLVLLLHKHRSILLRRLCSLMGTVFLLRCFTMFVTSSVPGQHLQCTGKIYGSV-SGHTVVL-----TMLNFFVTEYTPRSWNFLHTLSWVLNLFGIFFILAAH----EHYSIDVFIAFYITTRLFLYYHTLANTRAYQQSRRAR-FPMFSFFECNVNGTVPNEYCWPFSKPAIMKR........ 412
24 -12.300sp|Q8N6M3|FITM2_HUMAN Fat storage-inducing transmembrane protein 2 OS=Homo sapiens GN=FITM2 PE=2 SV=1  ali follow..  14  148..........................................................................................HGFDI-SGHSFLLTFCALMIVEEMSVLHEVKTDRSHCVALGILTFIWVLMFLCTAVY--FHNLSQKVFGTLFGLLSWYGTYGFW.................................................... 237
25 -11.900sp|A5D6W6|FITM1_HUMAN(removed signalp:1-34) Fat storage-inducing transmembrane protein 1 OS=Homo sapiens GN=FITM1 PE=1 SV=1  ali follow..  19  150................................................................................................SSHTFLLTFCCLLMAFAKYLAHGLPAGAPLRLVFLLNVLLLGLLLLCTVIY--FHQYTHKVVGAAVGTFAWYLTYGSW.................................................... 233
26 -9.030sp|Q5TGU0|TSPO2_HUMAN Translocator protein 2 OS=Homo sapiens GN=TSPO2 PE=2 SV=1  ali follow..  11  10......................................................LLPHLGPILVWLFTRDHMSGWCEGRMLSWC-----------PFYKVTAIYSVVGYASYLVWKDLGGGLGWPLALPLGLYAVQLTISWTVLVLFFTVHNPGLALLHLLLLYGLVVSTALIWHPI----------NKLAALLLLPYLAWLTVTSALTYHLWRDSLCPVHQPQPT 166
FFAS is supported by the NIH grant R01-GM087218-01
1 4 8 3 4 1   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Jaroszewski L, Slabinski L, Wooley J, Deacon AM, Lesley SA, Wilson IA, Godzik A. Genome pool strategy for structural coverage of protein families. Structure. 2008 Nov 12;16(11):1659-67.