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Query: [S] KOG4030 Uncharacterized conserved protein, contains SPRY domain, from COG1018

Results of FFAS03 search in H.sapiens
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MATSVLCCLRCCRDGGTGHIPLKEMPAVQLDTQHMGTDVVIVKNGRRICGTGGCLASAPLHQNKSYFEFKIQSTGIWGIGVATQKVNLNQIPLGRDMHSLVMRNDGALYHNNEEKNRLPANSLPQEGDVVGITYDHVELNVYLNGKNMHCPASGIRGTVYPVVYVDDSAILDCQFSEFYHTPPPGFEKILFEQQIFLast
1 -87.800sp|Q5W111|CLLD6_HUMAN Chronic lymphocytic leukemia deletion region gene 6 protein OS=Homo sapiens GN=CLLD6 PE=1 SV=2  ali follow..  100  1MATSVLCCLRCCRDGGTGHIPLKEMPAVQLDTQHMGTDVVIVKNGRRICGTGGCLASAPLHQNKSYFEFKIQSTGIWGIGVATQKVNLNQIPLGRDMHSLVMRNDGALYHNNEEKNRLPANSLPQEGDVVGITYDHVELNVYLNGKNMHCPASGIRGTVYPVVYVDDSAILDCQFSEFYHTPPPGFEKILFEQQIF 196
2 -48.200sp|Q5XPI4|RN123_HUMAN E3 ubiquitin-protein ligase RNF123 OS=Homo sapiens GN=RNF123 PE=1 SV=1  ali   15  79............EESQGQVEGRLGPSTVVLDHTGGFEGLLLVDDDLLGVNFGTIRSTTCVYKGKWLYEVLISSQGLMQIGWCTISCRFNQEGVGDTHNSYAYDGNRVRKWNVTTT---NYGKAWAAGDIVSCLIDDGTLSFCLNGVSLGTAFENLSMAYFPAISLSFKESVAFNFGPLRYPV-AGYRPLQDPPS.. 269
3 -47.300sp|Q92736|RYR2_HUMAN Ryanodine receptor 2 OS=Homo sapiens GN=RYR2 PE=1 SV=3  ali   16  24..........................AVRSNQHLICDNLLPGRDLLLQTNIFLGVSEGSAQYKKWYYELMVDEATHLRVGWASTEGYSPGNGVGDDLFSYGFDGLHLWSGCIARTVSSPNQHLLRTDDVISCCLDAPSISFRINGQPVQGMFENFNGLFFPVVSFSAGIKVRFLLGEFKFLPPPGYAPCYEA.... 225
4 -45.700sp|Q15413|RYR3_HUMAN Ryanodine receptor 3 OS=Homo sapiens GN=RYR3 PE=1 SV=2  ali   17  11..........................AVRANQNLICDNLLPRRNLLLQTNIFLGVAEGSAQYKKWYFELIIDEPTHLRVGWASSSGYAPGNGVGDDLYSYGFDGLHLWSGRIPRAVASVNQHLLRSDDVVSCCLDVPSISFRINGQPVQGMFENFNGLFFPVMSFSAGVKVRFLMGEFKFLPPSGYAPCYEAL... 213
5 -45.500sp|Q96DX4|RSPRY_HUMAN(removed signalp:1-16) RING finger and SPRY domain-containing protein 1 OS=Homo sapiens GN=RSPRY1 PE=2 SV=1  ali follow..  16  289............GRQLTYEKVNLSSIRAMLNSNDVSEYLKISPHGLEARCDASVRCTFCVDAGVWYYEVTVVTSGVMQIGWATRDSKFLNHEIGDDEYSCAYDGCRQLIWYNARSKP-HIHPCWKEGDTVGFLLDEKQMIFFLNGNQLPPEKQVFSSTFFAAASFMSYQQCEFNFGPFKYPPSMKFSTFNDYAFL. 484
6 -45.300sp|P21817|RYR1_HUMAN Ryanodine receptor 1 OS=Homo sapiens GN=RYR1 PE=1 SV=3  ali   17  9.......................NGVAVRSNQDLITENLLPGRELLLQPNIFVGRAEGTTQYSKWYFEVMVDQATHLRVGWALTEGYTPYPGVGDDLYSYGFDGLHLWTGHVARPVTSPGQHLLAPEDVISCCLDVPSISFRINGCPVQGVFESFNGLFFPVVSFSAGVKVRFLLGEFKFLPPPGYAPCH...... 211
7 -45.300sp|Q9UBL3|ASH2L_HUMAN Set1/Ash2 histone methyltransferase complex subunit ASH2 OS=Homo sapiens GN=ASH2L PE=1 SV=1  ali   20  66............KPIPGDLYRACLYERVLLALHDRAPQLKISDDRLTVKGYSMVRASHGVRKGAWYFEITVDEDTAARLGWSQPLGNLQA-PLGYDKFSYSWRSKKGTKFHQSIGK--HYSSGYGQGDVLGFYINHSEIIFYKNGVNQGVAYKDIEGVYFPAISLYKSCTVSINFGPFKYPPKDTYRPMS...... 295
8 -44.800sp|Q96A44|SPSB4_HUMAN SPRY domain-containing SOCS box protein 4 OS=Homo sapiens GN=SPSB4 PE=1 SV=1  ali follow..  14  42...............DMPAAGLAVQLRHAWNPEDRSLNVFVKDDDRLTQSTDGIRGKVGHARGLHAWQINWPARTHAVVGVATARAPLHSVGVGSDAESWGWDLGRSRLYHDGKNQPLGPDEAFALPDSLLVVLDEGTLSFIVDGQYLGVAFRGLKGKLYPVVSAWGHCEVTMRYIN................... 228
9 -43.400sp|Q6PJ21|SPSB3_HUMAN SPRY domain-containing SOCS box protein 3 OS=Homo sapiens GN=SPSB3 PE=1 SV=2  ali follow..  19  98....................EEDEYFDWVWDDLNKSSATLLSCDNRKVSGTAAIRGTKELGEGQHFWEIKMTSPTDMMVGIGTSDVDLDKYRLGRDEDSWGLSYTGLLHHKGDKT---SFSSRFGQGSIIGVHLDHGTLTFFKNRKCIGVAATKLQKRFYPMVCSTAAKVTRSCASSLQYLCCHRLRQLRPDSG.. 293
10 -43.300sp|Q6VN20|RBP10_HUMAN Ran-binding protein 10 OS=Homo sapiens GN=RANBP10 PE=1 SV=1  ali   21  37.........RRLQRLYPAVNQQETPLPRSWSPKDKYNYIGLSQGNLRVKDAASVRATHPIPAGIYYFEVKIVSKGYMGIGLSAQGVNMNRLP-GWDKHSYGYHGDDGHSFCSSGTGQ-PYGPTFTTGDVIGCCVNNGTCFYTKNGHSLGIAFTDLPANLYPTVGLTPGEIVDANFGPFLFDIEDYMREWRAKVQ.. 238
11 -42.900sp|P0C2W1|FBSP1_HUMAN F-box/SPRY domain-containing protein 1 OS=Homo sapiens GN=FBXO45 PE=1 SV=1  ali follow..  16  101................PSYKAKIRAFQHAFSTNDCSRNVYIKKNGFTLHSTDGARTKIGFSEGRHAWEVWWEGGTVAVIGIATKRAPMQCQGLGSDDQSWGWNLVDNNLLHNGEVNGCNNAPKYQIGERIRVILDDKTLAFERGYEFLGVAFRGLPKCLYPAVSAVYNTEVTLVYLGKPLD............... 285
12 -42.700sp|Q99619|SPSB2_HUMAN SPRY domain-containing SOCS box protein 2 OS=Homo sapiens GN=SPSB2 PE=1 SV=1  ali follow..  13  39....................DLGAQRRHGWNPKDCSENIEVKEGGLYFESTDGARGKRGYSRGLHAWEISWPLETHAVVGVATALAPLQTDHLGSNSESWGWDIGRGKLYHQSKGPAGTQGEQLEVPERLLVVLDEGTLGYAIGGTYLGPAFRGLKGTLYPAVSAVWQCQVRIRYLGERRAEPHSLLHLSRLC... 234
13 -41.600sp|Q96BD6|SPSB1_HUMAN SPRY domain-containing SOCS box protein 1 OS=Homo sapiens GN=SPSB1 PE=1 SV=1  ali follow..  14  47....................SYDVQLLHSWNNNDRSLNVFVKEDDKLIQSTDAIRGKVGYTRGLHVWQITWQRGTHAVVGVATADAPLHSVGVGNNHESWGWDLGRNRLYHDGKNQPLEPDETFIVPDSFLVALDDGTLSFIVDGQYMGVAFRGLKGKLYPVVSAWGHCEIRMRYLN................... 228
14 -41.400sp|Q96S59|RANB9_HUMAN Ran-binding protein 9 OS=Homo sapiens GN=RANBP9 PE=1 SV=1  ali   20  1...........LKRLYPAVDEQETPLPRSWSPKDKFSYIGLSQNNLRVHDAASVRATHPIPAGIYYFEVKIVSKGYMGIGLSAQGVNMNRLP-GWDKHSYGYHGDDGHSFCSSGTG-QPYGPTFTTGDVIGCCVNNNTCFYTKNGHSLGIAFTDLPPNLYPTVGLTPGEVVDANFGPFVFDIEDYMREWRTKIQ.. 200
15 -41.300sp|Q92499|DDX1_HUMAN ATP-dependent RNA helicase DDX1 OS=Homo sapiens GN=DDX1 PE=1 SV=2  ali   22  117................................................KEWHGCRATKGLMKGKHYYEVSCHDQGLCRVGWSTMQASLD---LGTDKFGFGFGGTGKKSHNKQFDN---YGEEFTMHDTIGCYLDKGHVKFSKNGKDLGLAFEIPPQALFPACVL-KNAELKFNFGEFKFPPKDGFVALSKAPD.. 263
16 -40.500sp|Q92736|RYR2_HUMAN Ryanodine receptor 2 OS=Homo sapiens GN=RYR2 PE=1 SV=3  ali   16  14...........................LEAPDQDHAARAEVCSGTGERFRIFRAEKTYAVKAGRWYFEFETVTAGDMRVGWSRPGCQPDQ-ELGSDERAFAFDGFKAQRWHQGNE---HYGRSWQAGDVVGCMVDEHTMMFTLNGEILLDDSGDVGDGFIPVCSLGVAQVGRMNFGTLKYFTQEGYEPFAVNTN.. 194
17 -40.400sp|Q6ZTA4|TRI67_HUMAN Tripartite motif-containing protein 67 OS=Homo sapiens GN=TRIM67 PE=2 SV=3  ali   14  3....................QTSDVAWFTFDPNSGHRDIILSNDNQTATCSSVVLGTAAFSKGVHYWELHVDNHPDPAFGVARASVVKDMM-LGKDDKAWAMYDNNRSWFMHCNSHTNRTEGGVCKGATVGVLLDKHTLTFFINGQQQGTAFSHVDGVFMPALSLNRNVQVTLHTG---LEVPTNLGRPKLSGN.. 183
18 -40.300sp|Q9Y4D8|K0614_HUMAN Probable E3 ubiquitin-protein ligase C12orf51 OS=Homo sapiens GN=C12orf51 PE=1 SV=5  ali   18  2....................................RACMFSSHLTSVTRGTFIYATSPLPAPSFYWEIEIVSYGIVSFGFTTEAEKRDGAW-TNPVGTCLFHNNGRAVHYNLQWKSVRLDVTLSPGDVAGIGWEKGRVYFTYCGQRLSPYLEDVSGGMWPVVHIQKNTKTRANFGPFAYAEGQ............ 190
19 -39.900sp|Q15751|HERC1_HUMAN Probable E3 ubiquitin-protein ligase HERC1 OS=Homo sapiens GN=HERC1 PE=1 SV=2  ali   14  66............QKQGELEEEDENLPIQEVSFDPEKAQCCLVENGQILTGKGYGLASTGVTSGCYQWKFYIVKENR-GTCVGVSRWPVHDFNHRTTSDMWLYRAYSGNLYHNG--EQTLTLSSFTQGDFITCVLDARTISFGKNGEEPKLAFEDVDAELYPCVMFNPGEKVKICDMRGTPRDLLPGDPICSPVA.. 259
20 -39.600sp|Q1KMD3|HNRL2_HUMAN Heterogeneous nuclear ribonucleoprotein U-like protein 2 OS=Homo sapiens GN=HNRNPUL2 PE=1 SV=1  ali   18  84...............EEAKDEEEDQTLVNLDTYTSDLHFQVSKDRYGGQPWSGARSTYGVTKGKVCFEAKVTQNSLLRVGWSVDFSRPQ---LGEDEFSYGFDGRGLKAENGQFE---EFGQTFGENDVIGCFANEVELSFSKNGEDLGVAFWISKRALLPHVLC-KNCVVELNFGQKEEPPPEEFVFIHAVPV.. 286
21 -39.000sp|P21817|RYR1_HUMAN Ryanodine receptor 1 OS=Homo sapiens GN=RYR1 PE=1 SV=3  ali   19  1............................NIEPPDQEPSQVENQSRCDRVRIFRAEKSYTVQSGRWYFEFEAVTTGEMRVGWARPELRPDV-ELGADELAYVFNGHRGQRWHLGSE---PFGRPWQPGDVVGCMIDENTIIFTLNGEVLMSDSGEIGDGFLPVCSLGPGQVGHLNLGVSSLRFQEGFEPFAINMQ.. 180
22 -39.000sp|Q15413|RYR3_HUMAN Ryanodine receptor 3 OS=Homo sapiens GN=RYR3 PE=1 SV=2  ali   18  2..................................EPSDQELADSAVEKVRFFRVERSYAVRSGKWYFEFEVVTGGDMRVGWARPGCRPDV-ELGADDQAFVFEGNRGQRWHQGSG---YFGRTWQPGDVVGCMINDASMIFTLNGELLELAFADYEIEFVPICCLGLSQIGRMNLGTFKFYTQEGFEPFAVNMN.. 180
23 -38.800sp|Q9BUJ2|HNRL1_HUMAN Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens GN=HNRNPUL1 PE=1 SV=2  ali   18  51.................EDEDDFDDTLVAIDTYNCDLHFKVARDRSSGYPWSGARASYGVRRGRVCFEMKINEPHVVRIGWSLDSCSTQ---LGEEPFSYGYGGTGKKSTNSRFE---NYGDKFAENDVIGCFADDVELSFTKNGKWMGIAFRIQKGQALYPHVLVKNCAVEFNFGAEPYCSVL............ 244
24 -38.800sp|Q00839|HNRPU_HUMAN Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens GN=HNRNPU PE=1 SV=6  ali   20  128.................EEDEHFDDTVVCLDTYNCDLHFKISRDRLSASSWAGGRASYGVSKGKVCFEMKVTEIHEVRIGWSLTTSGML---LGEEEFSYGYSLKGIKTCNCETE---DYGEKFDENDVITCFANEVELSYAKNGQDLGVAFKISKEPLFPHVLC............................... 300
25 -37.700sp|Q00839|HNRPU_HUMAN Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens GN=HNRNPU PE=1 SV=6  ali   19  1........................................ISRDRLSASSWAGGRASYGVSKGKVCFEMKVTEKIEVRIGWSLTTSGML---LGEEEFSYGYSLKGIKTCNCETE---DYGEKFDENDVITCFANEVELSYAKNGQDLGVAFKISKEVLFPHVLC-HNCAVEFNFGEKPYFPIPEEYTFIQN.... 178
26 -37.700sp|Q9C026|TRIM9_HUMAN E3 ubiquitin-protein ligase TRIM9 OS=Homo sapiens GN=TRIM9 PE=1 SV=1  ali   13  81....................QTSEVAWFAFDPGSAHSDIILSNDNLTVTCSSVVLGKTGFSKGIHYWELTVDNHPDPAFGVARMDVMKDVM-LGKDDKAWAMYDNNRSWFMHNNSHTNRTEGGITKGATIGVLLDRKNLTFFINDEQQGPAFDNVEGLFFPAVSLNRNVQVTLHTG---LPVPDFYSS........ 255
27 -34.200sp|O15344|TRI18_HUMAN Midline-1 OS=Homo sapiens GN=MID1 PE=1 SV=1  ali   14  30.....................KTNSQPFKLDPKSAHRKLKVSHDNLTVEGSYGVAGNVFIDSGRHYWEVVISGSTWYAIGLAYKSAPKHEW-IGKNSASWALCRCNNNWVVRHNSKEIPIEPAPHLRRVILLDYDNGSIAFYLNSIHLYTFDVAFAQPVCPTFTVWNKCLTIITGLP................... 205
28 -34.200sp|Q8WW59|SPRY4_HUMAN SPRY domain-containing protein 4 OS=Homo sapiens GN=SPRYD4 PE=1 SV=2  ali follow..  17  31..........................SFKLEEKTAHSSLALFRDDMRFREWAVVLADTAVTSGRHYWEVTVKRSQQFRIGVADVDMSRDSC-IGVDDRSWVFTYAQRKWYTMLANEKAPVEGIGQPEKVLLLEYEAQKLSLVSQVSVVHTLQTDFRGPVVPAFALWDGELLTHS...................... 199
29 -33.500sp|Q1KMD3|HNRL2_HUMAN Heterogeneous nuclear ribonucleoprotein U-like protein 2 OS=Homo sapiens GN=HNRNPUL2 PE=1 SV=1  ali   17  3.................................................................PMKEGCTEVSLLRVGWSVDFSRPQ---LGEDEFSYGFDGRGLKAENGQFE---EFGQTFGENDVIGCFANEVELSFSKNGEDLGVAFWISKDRALLPHVLCKNCVVELNFGEEPFFPPP............ 125
30 -33.100sp|Q8N3K9|CMYA5_HUMAN Cardiomyopathy-associated protein 5 OS=Homo sapiens GN=CMYA5 PE=1 SV=3  ali   12  2.............................LLRETAHPALHISSSGTRLTEIPSVLGEELPSCGQHYWETTVTDCPAYRLGICSSSAVQAG-ALGQGETSWYMHCSEPQRYTFFYSGIVSDVHVTERPARVGILLDNQRLIFIESEQLLFIIRHRFNEGVHPAFALEKPGKCTLHLG.................... 159
31 -32.800sp|Q9UJV3|TRIM1_HUMAN Probable E3 ubiquitin-protein ligase MID2 OS=Homo sapiens GN=MID2 PE=1 SV=3  ali   16  80.....................KTNSQPFKLDPKMTHKKLKISNDGLQMEKDEGAAGNIFIDSGCHYWEVVMGSSTWYAIGIAYKSAPKNEW-IGKNASSWVFSRCNSNFVVRHNNKEMLVDVPPHLKRLVLLDYDNNMLSFYANSLHLHTFDVTFILPVCPTFTIWNKSLMILS...................... 252
32 -31.400sp|A1L4K1|FSD2_HUMAN Fibronectin type III and SPRY domain-containing protein 2 OS=Homo sapiens GN=FSD2 PE=2 SV=1  ali   14  110.....................HTIGSYFRLNKDTCHPWLTISEDGLTAVRSEAVMGNLIPVRGHHYWEVEVDEHLDYRVGVAFADVRKQED-LGANCLSWCMRASSRHKYEFLHNRTTPDIRITVPPKKIGILLDHSKLSFFDLSQHLYTFSCQLHEFVHPCFSLEKPGCLKVHNG---ISMPKHVT......... 297
33 -31.400sp|Q9UBL3|ASH2L_HUMAN Set1/Ash2 histone methyltransferase complex subunit ASH2 OS=Homo sapiens GN=ASH2L PE=1 SV=1  ali   22  1............................................................................................LGYDKFSYSWRSKKGTKFHQSIGK--HYSSGYGQGDVLGFYINHSEIIFYKNGVNQGVAYKDIEGVYFPAISLYKSCTVSINFGPFKYPPKDTYRPMSDMGW.. 149
34 -31.300sp|Q14258|TRI25_HUMAN E3 ubiquitin/ISG15 ligase TRIM25 OS=Homo sapiens GN=TRIM25 PE=1 SV=2  ali   17  8..........................KVILDYNTAHNKVALSECYTRFTYCSQVLGLHCYKKGIHYWEVELQKNNFCGVGICYGSMNRQGSRLGRNSASWCVEWFNTKISAWHNNVEKTLPSTKATRVGVLLNCDHGFVIFFAVADKVHLMYKDFTEALYPAFWVSAGATLSI....................... 176
35 -31.000sp|Q8N3K9|CMYA5_HUMAN Cardiomyopathy-associated protein 5 OS=Homo sapiens GN=CMYA5 PE=1 SV=3  ali   13  144.....................STRGTRFLLLRETAHPALHISSSGTRLTEIPSVLGEELPSCGQHYWETTVTDCPAYRLGICSSSAVQAGA-LGQGETSWYMHCSEPQRYTFFYSGIVSDVHVTERPARVGILLDNQRLIFIESEQLLFIIRHRFNEGVHPAFALEK............................. 300
36 -30.500sp|Q15413|RYR3_HUMAN Ryanodine receptor 3 OS=Homo sapiens GN=RYR3 PE=1 SV=2  ali   20  173..................................................FFRVERSYAVRSGKWYFEFEVVTGGDMRVGWARPGCRPDV-ELGADDQAFVFEGNRGQRWHQGSG---YFGRTWQPGDVVGCMINDASMIFTLNGELLELAFADYENGFVPICCLGLSQIGR........................ 300
37 -30.200sp|Q5XPI4|RN123_HUMAN E3 ubiquitin-protein ligase RNF123 OS=Homo sapiens GN=RNF123 PE=1 SV=1  ali   14  1................................................................................WCTISCRFNQEEVGDTHNSYAYDGNRVRKWNVTTT---NYGKAWAAGDIVSCLIDDGTLSFCLNGVSLGTAFENLSMAYFPAISLSFKESVAFNFGPLRYPV-AGYRPLQDPPS.. 119
38 -29.600sp|Q96S59|RANB9_HUMAN Ran-binding protein 9 OS=Homo sapiens GN=RANBP9 PE=1 SV=1  ali   23  149.........RRLKRLYPAVDEQETPLPRSWSPKDKFSYIGLSQNNLRVHDAASVRATHPIPAGIYYFEVKIVSKGYMGIGLSAQGVNMNRLP-GWDKHSYGYHGDDGHSFCSSGTGQ-PYGPTFTTGDVIGCCVNNNTCFYTKNGHS................................................. 300
39 -29.600sp|Q6ZTA4|TRI67_HUMAN Tripartite motif-containing protein 67 OS=Homo sapiens GN=TRIM67 PE=2 SV=3  ali   16  147..............SKTVVLQTSDVAWFTFDPNSGHRDIILSNDNQTATCSSVVLGTAAFSKGVHYWELHVDNHPDPAFGVARASVVKDMM-LGKDDKAWAMYDNNRSWFMHCNSHTNRTEGGVCKGATVGVLLDKHTLTFFINGQQQGPAFSHVDG....................................... 299
40 -29.000sp|P21817|RYR1_HUMAN Ryanodine receptor 1 OS=Homo sapiens GN=RYR1 PE=1 SV=3  ali   19  150...........................YNIEPPDQEPSQVENQSRCDRVRIFRAEKSYTVQSGRWYFEFEAVTTGEMRVGWARPELRPDVE-LGADELAYVFNGHRGQRWHLGSE---PFGRPWQPGDVVGCMIDENTIIFTLNGEVLETAFREIEDGFLPVCSLGPGQVGH........................ 300
41 -28.600sp|Q9BXM9|FSD1L_HUMAN FSD1-like protein OS=Homo sapiens GN=FSD1L PE=2 SV=2  ali follow..  13  315...........VEDTCVEWDPTGGKGQESKIKGKENKGRSGTPSPKRTSVGSTVLGDTAIESGQHYWEVKAQDCKSYSVGVAYKTLGKFDQ-LGKTNTSWCIHVNNWLQNTAAKHNNKVKALDVTVPEKIGVFCDGGQLSFYDSKQLLYSFKTKFTQPVLPGFMVWCGG-LSLSTG---MQVPSAVRTLQKSEN.. 515
42 -27.300sp|Q7Z4K8|TRI46_HUMAN Tripartite motif-containing protein 46 OS=Homo sapiens GN=TRIM46 PE=2 SV=2  ali   11  85...........................LDSRWGASRERLAISKDQRAVRSVPVVLGDVAVTQGRSYWACAVDPASLVKVGVGLESKLQESFATVEASPPFAFGSGASSNAGLTGRDGPTAGCTVPLPPRLGICLDRGRVSFLVSFRGLLECPLDCSGPVCPAFCFIGGGAVQLQ...................... 289
43 -27.300sp|Q15751|HERC1_HUMAN Probable E3 ubiquitin-protein ligase HERC1 OS=Homo sapiens GN=HERC1 PE=1 SV=2  ali   12  1...........................................................................................NHRTTSDMWLYRAYSGNLYHNG--EQTLTLSSFTQGDFITCVLDARTISFGKNGEEPKLAFEDVDAELYPCVMFSSNPGEKVKICDMQM................ 91
44 -27.100sp|Q9BUJ2|HNRL1_HUMAN Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens GN=HNRNPUL1 PE=1 SV=2  ali   21  1..................................................................................................SYGYGGTGKKSTNSRFE---NYGDKFAENDVIGCFADDVELSFTKNGKWMGIAFRIQKEALYPHVLV-KNCAVEFNFGAEPYCSVLPGFTFIQH.... 102
45 -26.900sp|Q8NCJ5|SPRY3_HUMAN SPRY domain-containing protein 3 OS=Homo sapiens GN=SPRYD3 PE=1 SV=2  ali follow..  19  28.................RRRIREIREVRAFRYQERFKHILVDGDTLSYHGNGCYVASRPLTKDSNYFEVSIVDRGTIAVGLVPQYYSLDHQP-GWLPDSVAYHADDGKLYNGRAKGR-QFGSKCNSGDRIGCGIETAQIFFTKNGKRVGSTIMPMSDGLFPAVGMHSGEEVRLHLNA................... 201
46 -26.600sp|Q5W0U4|BSPRY_HUMAN B box and SPRY domain-containing protein OS=Homo sapiens GN=BSPRY PE=2 SV=1  ali follow..  17  226.....................LSGTEDIRIDERTVSPFLQLSDDRKRFDHWPNALAATSFQNGLHAWMVNVQNSCAYKVGVASGHLPRKGCRLGHNAFSWVFSRYDQEFRFSHNGQHEPLGLLRGPAQLVVLDLQVQELLFYASGTVLCAHHVSFPGPLFPVFAVADQTI.......................... 398
47 -26.600sp|Q9NQ86|TRI36_HUMAN E3 ubiquitin-protein ligase TRIM36 OS=Homo sapiens GN=TRIM36 PE=2 SV=2  ali   12  68..........................DEKCGYNNEHLLLNLKRDRVESRSLDYIIGDTGITKGKHFWAFRVEPYSYLKVGVASSDKLQEEQDSGHDSGSEDACFDSSQPFKSPTSSNEPENRVLPMPTSIGIFLDKGKVDFYDQMKCLYERQVDCSHTLYPAFALMGS-------GGIQLEEPITAKYLEYQEDM. 278
48 -26.000sp|Q14258|TRI25_HUMAN E3 ubiquitin/ISG15 ligase TRIM25 OS=Homo sapiens GN=TRIM25 PE=1 SV=2  ali   16  158..........................KVILDYNTAHNKVALSECYTRFTYCSQVLGLHCYKKGIHYWEVELQKNNFCGVGICYGSMNRQGSRLGRNSASWCVEWFNTKISAWHNNVEKTLPSTKATRVGVLLNCDHGFVIFFAVADKVHL.............................................. 299
49 -26.000sp|Q14142|TRI14_HUMAN Tripartite motif-containing protein 14 OS=Homo sapiens GN=TRIM14 PE=2 SV=2  ali follow..  19  268..........................TPTLDPDTMHARLRLSADRLRFDALWQVLARDCFATGRHYWEVDVQEAGAWWVGAAYASLRRRGARLGCNRQSWCLKRYDLEYWAFHDGQRSRLRPR-DDLDRLGVFLDAGVLAFYDGMSHLHTFRATFQEPLYPALRLWEGAI.......................... 436
50 -26.000sp|Q6ZWI9|RFPLB_HUMAN Ret finger protein-like 4B OS=Homo sapiens GN=RFPL4B PE=2 SV=2  ali follow..  14  94........................REDVTLDAATASSLLVFSNDLRSAQCKKCVLGTPCFSSGQHYWEVEVGEVKSWSLGVCKEPADRKSNDLFPEHGFWISMKAGAIHANTHLERIPASPRLRRVG--IFLDADLEEIQFF-DVDNNVLIYTFSLELLCPFFCL............................... 247
51 -25.900sp|Q9Y4D8|K0614_HUMAN Probable E3 ubiquitin-protein ligase C12orf51 OS=Homo sapiens GN=C12orf51 PE=1 SV=5  ali   16  128...............PPLQADRRQPKEITWSPSRVFPPVMFSSHLTSVTRGTFIYATSPLPAPSFYWEIEIVSYGIVSFGFTTEAEKRDGAW-TNPVGTCLFHNNGRAVHYNLQWKSVRLDVTLSPGDVAGIGWEKGRVYFTYCGQR................................................. 300
52 -25.800sp|Q92736|RYR2_HUMAN Ryanodine receptor 2 OS=Homo sapiens GN=RYR2 PE=1 SV=3  ali   17  163..........................NLEAPDQDHAARAEVCSGTGERFRIFRAEKTYAVKAGRWYFEFETVTAGDMRVGWSRPGCQPDQ-ELGSDERAFAFDGFKAQRWHQGNE---HYGRSWQAGDVVGCMVDEHTMMFTLNGEILLDDSG--SELAFKDFDVGDG............................ 300
53 -25.800sp|Q96LD4|TRI47_HUMAN Tripartite motif-containing protein 47 OS=Homo sapiens GN=TRIM47 PE=1 SV=2  ali   17  129..........................IVDLDSDTADKFLQLFGTKGRFTHCEQVLGEGALDRGTYYWEVEI-IEGWVSMGVMAEDFSPDRGRLGRNAHSCCLQWNGRSFSVWFHGLEAPLPHPFSPTVGVCLEYADRALAFYRDGKMSLLRRLKASRPRRGGIPASPIDPFQS....................... 295
54 -25.500sp|Q9BTV5|FSD1_HUMAN Fibronectin type III and SPRY domain-containing protein 1 OS=Homo sapiens GN=FSD1 PE=1 SV=1  ali follow..  13  301..........................KAREKDGKGRTASPINSPARGTPSPKTVLGDTLIDGGEHYWEVRYEDSKAFGVGVAYRSLGRFEQ-LGKTAASWCLHVNNWLQVSTAKHANKVKVLDAPVPDCLGVHCDQGLLSFYNTKQVLHTFKTRFTQPLLPAFTVWCGSFQVTT----GLQVPSAVRCLQKRGS.. 486
55 -25.300sp|Q8WV44|TRI41_HUMAN E3 ubiquitin-protein ligase TRIM41 OS=Homo sapiens GN=TRIM41 PE=1 SV=3  ali   12  2..............................GVRLAERRQEVADHPKRFSADCCVLGAQGFRSGRHYWEVEVGGRRGWAVGAARESTHHKEQQPLLQREVWCVGTNGKRYQAQSSTEQTLLSPSEKPRRFVYLDYEAGRLGFY-NAETLAHVHT-LGERVFPFFRVLSKGT.......................... 174
56 -25.300sp|O15553|MEFV_HUMAN Pyrin OS=Homo sapiens GN=MEFV PE=1 SV=1  ali   12  2.............................LDAETAYPNLIFSDDLKRFDSCIIVLGSPSFLSGRRYWEVEVGDKTAWILGACKTSISRKGMTLSPENGYWVVIMMKENEYQASSVPPTRLLIKEPPKRVIFVDYRVGSISFY-NVTARSHIYTSFSGPLQPIFS................................ 157
57 -25.100sp|Q6PJ69|TRI65_HUMAN Tripartite motif-containing protein 65 OS=Homo sapiens GN=TRIM65 PE=1 SV=3  ali follow..  8  332..........................NLTFDPVSANRHFYLSRQDQQVKHCRQVQCAQSFQAGHHYWEVRASDHS-VTLGVSYPQLPRCRLNIGRGPCSWGLCVQEDSLQAWHNGEAQRLPGVSGRLLGMDLDLASGCLTFYSQTQPLYTFHALFNQPLTPVFWLLEGRTLTL-------HQPGAVFPLGPQEEVL 516
58 -24.800sp|O95361|TRI16_HUMAN Tripartite motif-containing protein 16 OS=Homo sapiens GN=TRIM16 PE=1 SV=3  ali follow..  15  374..........................DITFDPDTAHKYLRLQEENRKVTNTTQVLSQQSLYLHRYYFEVEIFGAG-TYVGLTCKGIDRKGSCISGNNFSWSLQWNGKEFTAWYSDMETPLKAGPFRRLGVYIDFPGGILSFYGTMTLVHKFACKFSEPVYAAFWLSKKEN-AIRIVDLGEEPEK............ 554
59 -24.800sp|Q8IUD6|RN135_HUMAN E3 ubiquitin-protein ligase RNF135 OS=Homo sapiens GN=RNF135 PE=1 SV=2  ali follow..  20  260..........................HPTFNLKSLSCSLEVSKDSRTVTSTSQVLCSQALSSGKHYWEVDTRNCSHWAVGVASWEMSRDQ-VLGRTMDSCCVEWKGTSQLSAWHMVKETVLGS-DRPGVVGIWLNEGKLAFYSQEKLLYECTISASSPLYPAFWLHPGNYLII....................... 427
60 -24.400sp|P21817|RYR1_HUMAN Ryanodine receptor 1 OS=Homo sapiens GN=RYR1 PE=1 SV=3  ali   9  46..............................AMMTQPPATPTLPRLPHDVVPADNRDDPEIILTTYYYSVRVQEPSCVWAGWVTPDYHQHDMSFDLSKTMGDEQGNVHMVWGGDFVSPGQQGRISHTDLVIGCLVDTGLMTFTANGKESNTFFQVEPNKLFPAVFVTHQNVIQFELGKQKNIMPLSAAMFQSERK.. 234
61 -24.000sp|Q9C037|TRIM4_HUMAN Tripartite motif-containing protein 4 OS=Homo sapiens GN=TRIM4 PE=2 SV=2  ali follow..  18  308..........................AVNLAEDTAHPKLVFSQEGRRFQHLPCVLGKNVFTSGKHYWEVESRDSLEVAVGVCREDVMGITSKMSPDVGIWAIYWSAAGYWPLIGFPGTPTQQEPALHRVVYLDRGTGNVSFYVDGVHLHTFSCSSVSRLRPFFWLSPLASLVI....................... 493
62 -23.900sp|Q96JN8|NEUL4_HUMAN Neuralized-like protein 4 OS=Homo sapiens GN=NEURL4 PE=1 SV=2  ali   21  75................................PNCGQKAAITHEGRTALNHGVVLSSRALRDGE-VFQVRIDKAGSIEIGVTTHNPAYLQLPTNLRSGTWMMTGNGVMHNGTTILDEYGNLDRLKAGDTVGVVRRDGTLHFFVNGMTQGPAAWNVPPGVYAVVDLY-GQAAQATI..................... 233
63 -23.800sp|Q8NG06|TRI58_HUMAN Tripartite motif-containing protein 58 OS=Homo sapiens GN=TRIM58 PE=2 SV=2  ali follow..  14  292..........................DVKLDPATAHPSLLLTADLRRFDTWPCILGLQSFSSGRHYWEVLVGEGAEWGLGVCQDTLPRKGTTPSPENGVWALWLLKGNEYMVLASPSVPLLQLESPRCIIFLDYEAGEISFYTDGSYIYTFNQLFSGLLRPYFFICDATPLIL....................... 458
64 -23.800sp|O15344|TRI18_HUMAN Midline-1 OS=Homo sapiens GN=MID1 PE=1 SV=1  ali   14  180.....................KTNSQPFKLDPKSAHRKLKVSHDNLTVERDEGVAGNVFIDSGRHYWEVVISGSTWYAIGLAYKSAPKHEW-IGKNSASWALCRCNNVRHNSKEIP................................................................................ 294
65 -23.800sp|Q96LD4|TRI47_HUMAN Tripartite motif-containing protein 47 OS=Homo sapiens GN=TRIM47 PE=1 SV=2  ali   16  10..........................................LSPTRFTHCEQVLGEGALDRGTYYWEVEI-IEGWVSMGVMAEDFSPDRGRLGRNAHSCCLQWNGRSFSVWFHGLEAPLPHPFSPTVGVCLEYADRALAFYRDGKMSLLRRLKASRPRRGGIPASPIDPFQSRLGLFTHRLKPAFFLESVDAHL. 172
66 -23.300sp|Q495X7|TRI60_HUMAN Tripartite motif-containing protein 60 OS=Homo sapiens GN=TRIM60 PE=2 SV=2  ali follow..  11  296..........................DVILDLNTAHPQLLVSEDRKAVRVCPAVLGSQRFSSGRHYWEVEVGNKPKWILGVCQDCLLRNWDQPSVLGGFWAIGRYMKSGYVASGPKTTQLLPVVKPSKIIFLDYELGDLSFYNDRSILYTFNDCFTEAVWPYFYTGTDSE.......................... 459
67 -23.300sp|Q96PL5|ERMAP_HUMAN(removed signalp:1-29) Erythroid membrane-associated protein OS=Homo sapiens GN=ERMAP PE=1 SV=1  ali follow..  14  210..........................AVTLDPDTAHPKLILSEDQRCVRFVVSILGSEYFTTGCHYWEVYVGDKTKWILGVCSESVSRKGVTASPANGHWLLRQSRGNEYEALTSPQTSFRLKEPPRCVIFLDYEAGVISFYTNKSHIFTFTHNFSGPLRPFFE................................ 367
68 -23.100sp|Q9C029|TRIM7_HUMAN Tripartite motif-containing protein 7 OS=Homo sapiens GN=TRIM7 PE=1 SV=2  ali follow..  15  343..........................ELTLDPDTANPRLILSLDLKRFDTNTRVLASCGFSSGRHHWEVEVGSKDGWAFGVARESVRRKGTPFTPEEGVWALQLNGGQYWAVTSPERSPLSCGHLSRVRVALDLEVGAVSFYEDMRHLYTFRVNFQERVFPLFSVCSTGT.......................... 505
69 -23.100sp|A6NLU0|RFPLA_HUMAN Ret finger protein-like 4A OS=Homo sapiens GN=RFPL4A PE=1 SV=3  ali follow..  15  97..........................DMTFDVDTANNYLIISEDLRRFDTALCVLGTPRFTSGRHYWEVDVGTSQVWDVGVCKESVNRQGIVLSSEHGFLTVGCREGKVFAASTVPMTPLWVSPQLHRVIFLDVGMRSIAFY-NVSDGCHIYTPVCEPWRPFFAH............................... 256
70 -23.100sp|O00635|TRI38_HUMAN Tripartite motif-containing protein 38 OS=Homo sapiens GN=TRIM38 PE=2 SV=1  ali follow..  16  293..........................SVTLDPDTAHHELILSEDRRRFTAFPCVLGCEGFTSGRRYFEVDVGEGTGWDLGVCMENVQRGTMKQEPQSGFWTLRLCKKKGYVALTSPPTSLHLHEQPLLVIFLDYEAGVVSFY-NGNTGCHIFTSFSDTLRPYFQVYQYSPLFL....................... 460
71 -23.000sp|A6NK02|TRI75_HUMAN Tripartite motif-containing protein 75 OS=Homo sapiens GN=TRIM75 PE=2 SV=2  ali follow..  13  295..........................EIILDPETAHPNLIVSEDKKRVRVKPVVLGFPYFHSGRHFWEIEVGDKSEWAIGICKDSLPTKARPSSAQQECWRIELQDDGYHAPGAFPTPLLLEVKARAIGIFLDYEMGEISFYAEKSHICTFTDTFTGPLRPYFYVGPDSQ.......................... 457
72 -22.900sp|Q309B1|TR16L_HUMAN Tripartite motif-containing protein 16-like protein OS=Homo sapiens GN=TRIM16L PE=2 SV=3  ali follow..  15  158..........................DITFDPDTAHKYLRLQEENRKVTNTTQVLSQQSLYLHRYYFEVEIFGAG-TYVGLTCKGIDQRSSCISGNNFSWSLQWNGKEFTAWYSDMETPLKAGPFWRLGVYIDFPGGILSFYGSMTLVHKFACKFSEPVYAAFWLKKENAIRI....................... 329
73 -22.900sp|Q86WT6|TRI69_HUMAN Tripartite motif-containing protein 69 OS=Homo sapiens GN=TRIM69 PE=2 SV=2  ali follow..  14  324..........................PLTLDPKTAHPNLVLSKSQTRFDSSVAVLGSRGFTSGKWYWEVEVAKKTKWTVGVVRESIIRKGCPLTPEQGFWLLRLRNQTDLKALDLPSFSLTLTNNLDKVIYLDYEGGQLSFYKTMTHIYTFSNTFMEKLYPYFCPCLNDG---NKEPLHILHPQ............ 500
74 -22.900sp|O75678|RFPL2_HUMAN Ret finger protein-like 2 OS=Homo sapiens GN=RFPL2 PE=2 SV=3  ali follow..  11  187..........................DMTLDANTANNFLLISDDLRRFDVSVCILGSPRFTCGRHCWEVDVGTSTEWDLGVCRESVHRKGIQLTTELGFWTVSLRDGGRLSATTVPLTFLFVDRKLQRVIFLDMGMQNVSFF-DAESGSHVYTSAEEPLRPFLA................................ 345
75 -22.900sp|Q9BVG3|TRI62_HUMAN Tripartite motif-containing protein 62 OS=Homo sapiens GN=TRIM62 PE=2 SV=1  ali follow..  13  296..........................ALTLDPGTAHQRLILSDDCTRFDVEVSVLGSEAFSSGVHYWEVVVAEKTQWVIGLAHEAASRKGIQIQPSRGFYCIVMHDGNQYSACTEPWTRLNVRDKLDKVVFLDYDQGLLIFYDDMSWLYTFREKFPGKLCSYFSPGQSHANGKNVQPLRINTVR............ 474
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Jaroszewski L, Slabinski L, Wooley J, Deacon AM, Lesley SA, Wilson IA, Godzik A. Genome pool strategy for structural coverage of protein families. Structure. 2008 Nov 12;16(11):1659-67.