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Query: [E] COG0287 Prephenate dehydrogenase, from COG1018

Results of FFAS03 search in HGM_OVER
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MMGDIMFERIALIGIGLIGSSIARDVRELGLARHVVISTRSEDTLKRAEELALGTDYTVSAAEAVKDADLVIVSVPVGASESVAQQIAPYLKPSAIVTDVGSTKASVIAQMAPHMPENVHFIPGHPLAGTEKSGPDAGFAGLFRERWCIFTPLPGTDAAALERLKDFWRALGSRVDEMDAEHHDKVLAIVSHLPHIIAYNIVGTADDLETVTESEVIKYSASGFRDFTRLAASDPTMWRDVCLHNKDAILEMLARFSEDLASLQRAIRWGEGDKLFELFSRTRSIRRSIIEAGQDVDTPDFGRHALDQKKLast
1 -3.490PB003645 Q65HI2_BACLD/1-230 PB003645; Pfam-B_3645;  ali follow..  16  113...........IIGVEDV--SIVVNVDATSLKIFEKNRKTQETSTNETDKQG----GKRTVSEMSSDEEIVIIKNGDKETPVVVQTKKPDIRGVLVVAQGVDIKKTIIEAVTRVLDVPSHRVAVAPKKMKED.................................................................................................................................................................................. 230
2 -3.030PB012991 Q2RHT0_MOOTA/1-175 PB012991; Pfam-B_12991;  ali follow..  11  27FLKGVFLLRIAVVD-GGIGKHITARLRQEPPEVEILALGTNAAATVAMIKAGANEGATGEIIYNAPRVEAITGSLAIILADAMLGELTPAMAAAIAASPA.................................................................................................................................................................................................................. 131
3 -3.020PB005346 A0R807_PELPD/1-258 PB005346; Pfam-B_5346;  ali follow..  11  1.................MTDSLFWAIDIKNQMSQINQTTSGNFYSHRNITDQVLENFTDALDCL--TAHLMLECSEVLA-----------VKPANLISIVNRTRPCGRNLYLLWQQHHTDLA-------QRLNNLNFMVLQSRQQSLLLLCYDHVRLEHHLSGIRTLLHKAGYKDDADCEGMLLELIGGNNSFPHEIGLFIGYPAKDVA-------------AFMGLVRLPFTCQRLWK--IYGNPARSLALAEQYRCCRNKMGAILARG--TSKTLEIDRSDH.......................... 243
4 -2.780PB050904 Q64SA2_BACFR/1-230 PB050904; Pfam-B_50904;  ali follow..  8  1.MKSRIISLGLVASLVCLLPQVAEAQIAASNPLEWTALAEGNELINGQIEKQIKGQTQTALLQNSIATEFNQIHKWEKQYNSYLKTASGYASSLKACTHLYNDGVRIFLTLGKLG----KAIQNNPQGIVASMNMNNLYIETATELVSVF-----------TLLNDAVAKGSNENMLTGAERSKTLWALNDQLSDFSRKLHLLYLSIRYYTFNDVWNNVTAGMLDRDNGAARMALSHWH....................................................................... 224
5 -2.430PB022815 A4DEQ0_LISMO/1-452 PB022815; Pfam-B_22815;  ali follow..  13  293..............................................................................................................................................................DYLNLMRDLNIAIDSENIIMPKIAHDNAVKLLYQMKH-YAFIVPKQASDLLTEGKALSHCVGGSNYIK--QHIEGKTTIIFVRDKQDLEKSLYTLEYKNGQIYQLRGKHNCDPTKDVQMAANKAKLLKSKTKVLQN................ 452
6 -2.300PB040621 Q8A865_BACTN/1-132 PB040621; Pfam-B_40621;  ali follow..  12  11...................................................................................................................................................................................................ALVLTMCSAFSLKKGHSKTVYAFGIAASFTDTVVYFTDIQIL--DSAKVSKEGFLTHRDLYSYQLKNYVEDNGLQQNSTCMIYFSENRKKLEK...................... 101
7 -2.300PB001934 Q6PSL5_CHLRE/821-1150 PB001934; Pfam-B_1934;  ali follow..  11  52............................................................PRWSLGRNARLLMVIPMDAETPGGRLLRPQAQ---VMEEAIRHWATVLSVRLDLDAARGKLGPEACEMERQRFDGVIAMMERNDGPTLVVTLDRSSGRPLVPILDPFVEGLGDRVLISEACNHNRITSACNQIPNKLEAALGGKKLQIEHAFGREFPELESGGMDGLKLAIHCGG------CMIDAQKMQQRMKDLHEA................................................... 281
8 -2.160PB003142 Q8DVS6_STRMU/1-162 PB003142; Pfam-B_3142;  ali follow..  12  4.....................................................................................................................SVTFPPGRPLSNFLLEGTIMKLTVYFDGTFWFALVEHVNRKGQYKVFRYPFGK--------EPKDSDIWNFIAKKLPSLIKKYDHIKTSSHADSIPQP---------KRMQRVLNKSKKQ-SAVSTKAQAEMQKLHEALKKEKKSQSKEKRQALKQYKYQLKQEKRHQKRQ...................... 161
9 -1.810PB018258 Q7MT99_PORGI/1-157 PB018258; Pfam-B_18258;  ali follow..  15  71.................................................................................................................................................................................................................................TPVLFAHGITHLYDELPHHAVQSLKHRLLTYFGKTTYYRRYITIQEQDYIRDSFVRAGFSSDLI..................... 139
10 -1.790PB000790 _Gut.Meta.Jp.0111831_ gi|163310496|dbj|BABD01000203.1||3 (- 2591:4589~0 complete)  ali follow..  13  232..WESYFLLAEAAEYGWISNITPKEAYELGIRSSFEYFGVSEYADQYINSTTRNRLGTSAFDDTVEPTSEVMTYRDGYTNTDQIQEVVYNYPTASKTLYGKAMNDHLTKIITQ------KYIAQMPYQVLERLGLPF------------FEIPANESDLI-----------GSDMVNVLKKDSWKNGQQWDFYPQRMRYPTTLDNADPENYQKA------------VELLGGSDTPLW........................................................................ 436
FFAS is supported by the NIH grant R01-GM087218-01
1 4 8 3 4 1   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Robinson-Rechavi M, Godzik A. Structural Genomics of Thermotoga maritima Proteins Shows that Contact Order Is a Major Determinant of Protein Thermostability. Structure (Camb). 2005 Jun;13(6):857-60.