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Query: [E] COG0345 Pyrroline-5-carboxylate reductase, from COG1018

Results of FFAS03 search in HGM_OVER
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MENQKIGFIGAGKMGSALMQGTIKAGIVTPENIGASDVYEPFLKDLQAKLGIRVSTDNAVIVRESDILILAVKPQTLSSVLSNLKNEITSEKLVISIAAGVPLSTYEDALLEGTRVVRVMPNIAATVSEAASGIAPGKNATPEDLKAALEIFSAVGTAVQVPESLMDAVTGLSGSGPAFIFPVIEAMADGAVLEGMDRKSALTLAAQTVLGAAKMALETGMHPGELKDMVTSPAGTTIQGIHSLEEAGIRAAFMNAVIRASERSKELGKKLast
1 -3.980PB003645 Q65HI2_BACLD/1-230 PB003645; Pfam-B_3645;  ali follow..  10  29..........................................................................................HYFLLLFVLGVSFMLVSQIFSSEPS-ADQPAASQKATSESTVQSGEGEKEVFKPASDDKPKESIQDYEQEYENQLKDILETIIGVEDVSIVVNVDATSLKIFEKNRKTQETSTNETDKQGGKRTVSEMSSDEEIVIIKNVVQTKKPDIRGVLVVAQGVDNVQIKKTIIEAVTRVLDVPSH 218
2 -2.970PB006791 A6TXD6_9CLOT/1-181 PB006791; Pfam-B_6791;  ali follow..  14  46...............................................................................................RLVKGTDGKNIESVLMQHIEKVEEAQVEVEKVHKRLDII----------NNRMSFCIQKVGMV------RYNAFADMGSD--SYSYALLDENNNGMIITGIYGRSETVTYAKPVK-----------------------DGKSNYSLSVEELQALQRAKENTIDTLELQGFRSKKE 180
3 -2.810PB144506 _Gut.Meta.Jp.0101058_ gi|162866171|dbj|BABB01003836.1||1 (- 121:946~0 complete)  ali follow..  11  76......................................................................SLKITIDENLFPLLSIKSNNGRLAIRIQDGTRIK------PTQYVIEGSSKTLKYLKTSGPMDFEAQNAFSEDQLEIKIS-VSGSGDLVFADLDCKNLTSKVSGSGDITLKGKADEA................................................................................... 204
4 -2.540HGC00106 gi|162841414|dbj|BABA01003295.1|1.0 TMP01000;  ali follow..  21  31..............................................................................................................................................................VYVSGNNLFCITGYSGLDP-------ELDISNVQAPGVEYRDTYPTTRSFTFG........................................................... 76
5 -2.260PB027498 Q7MTK6_PORGI/1-146 PB027498; Pfam-B_27498;  ali follow..  11  2..........................................................................................SNILILIIGVLVLGLVAALIRHSHKRRAAEAKGESLPEEPVRVVPPGCCGMHITCEKDSLLTAVSKSIVYYDDEELDRYAGVLPE--EYNTEAVEEF----------EEILSTLQEEEVPSWIRSLQMRQIQPISIKEQA........................................ 132
6 -2.230PB001404 Q2S5L8_SALRD/1-256 PB001404; Pfam-B_1404;  ali follow..  16  4..........................................................................................................................................................................SISGSGPTPTSSTLPLTPYTPAMPFLTRSRIARVASLLSAGVLALVLLSCDGVGDFGDTNEDPTTANDPNPDLE.......................... 79
7 -2.230HGC01024 gi|162869036|dbj|BABB01000971.1|4.0 TMP01399;  ali follow..  15  28......NIIQPDRMENILYDYHLSISMGNNLSYSDNYQKEAYKNYVFEKHHITEAE-------DSSMVWYTRHTEELASLYKKLGERFRSEKKHMQ.............................................................................................................................................................................. 111
8 -2.180PB007011 gi|160888195|ref|ZP_02069198.1| hypothetical protein BACUNI_00603 [Bacteroides uniformis ATCC 8492]gi|156862330|gb|EDO55761.1| hypothetical protein BACUNI_00603 [Bacteroides uniformis ATCC 8492]  ali follow..  8  13..................................................................IRIICTEPLFFTSLCDKLLDE-IPQPDIPEEKPSMADRGLYKNKKKRVKGKKDKLQPEVQGQPPLSWIRLSRKKLNEGVDEAWAVFDK--AFEEAEKLIDDKKVNIAFSSRSFEYYLL--LHFEYLYHPFHATECGERIDGKKVNYNCMTEKSKENACHGEKCINGYARLKKYWNETKTSQSTFPLIEKRLKAGIINAKRLRIE 234
9 -2.130PB009510 _JGI.0345302_ 2004041369 [Human Gut Community Subject 8]  ali follow..  10  12..............................................................................................................................................DKSYVGKWMFQVMGLEYDKALKLAEELPE------FFPETATWGLCWHEIKWGLPVQENLSYQERRQAIYEKRDYHSPMTPYIMERYLENATGFTVHIADCHDAGPL..................... 113
10 -2.030PB003564 gi|46242789|gb|AAS83494.1| TraD [Bacteroides fragilis]  ali follow..  16  63..........................................................................................................SDIIGKSRFKMASTRTTAAIPTQEAATSEKGIELSEEEATFDDGNTETVSRPTQVPEDKLDETFTSIPPSEL------EYGEDKPEDEEPDKKQASGSSFEDIDMAVHTIWKESPSDEEMRH--------AGKVMTELDGTELFTRITERLEAMSERLAKA... 211
FFAS is supported by the NIH grant R01-GM087218-01
1 4 8 3 3 7   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Plewczynski D, Tkacz A, Wyrwicz LS, Godzik A, Kloczkowski A, Rychlewski L. Support-vector-machine classification of linear functional motifs in proteins. J Mol Model 2006 Aug;12(4):453-61. Epub 2005 Dec 10.