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Query: [R] COG0705 Uncharacterized membrane protein (homolog of Drosophila rhomboid), from COG1018

Results of FFAS03 search in HGM_OVER
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MLMITSFANPRVAQAFVDYMATQGVILTIQQHNQSDIWLADESQAERVRGELARFIENPGDPRYLAASWQSGQTNSGLRYRRFPFLATLRERAGPVTWIVMLACVLVYIAMSLIGDQTVMVWLAWPFDPVLKFEVWRYFTHIFMHFSLMHILFNLLWWWYLGGAVEKRLGSGKLIVITVISALLSGYVQQKFSGPWFGGLSGVVYALMGYVWLRGERDPQSGIYLQRGLIIFALLWIVAGWFDWFGMSMANGAHIAGLIVGLAMAFVDTLNARKRTLast
1 -5.050PB046158 _JGI.0336690_ 2004028347 [Human Gut Community Subject 8]  ali follow..  3  93........TDENIKSFDRVARKYGIDYSLKKEVGAD--FFKAKDVDVMTAAFREYAGVELKKKQVKKPSVRKKLQKSVERKAKHRQRVKQRQK....................................................................................................................................................................................... 181
2 -4.180PB021133 Q64YN4_BACFR/1-310 PB021133; Pfam-B_21133;  ali follow..  6  14.......NNAGSSRQLANYLEHEDLERMEKGLYTDSFFNLTENNIYKVIKDIDSNIGQLLKTDAKFYAIHVSPSEKELQAMGNTEHEQAESMKRYIREVFIPEYAKNF-------NKGLSEADIKFYGKIHFNRSHS--NELNMH---CHLIVS.......................................................................................................................... 151
3 -3.900PB032242 Q8FLW6_COREF/1-257 PB032242; Pfam-B_32242;  ali follow..  9  1.......................................................MAITSAPPVTTPAPTAQSVAADAAMSRFETQTSRYGSLTMTAGLILSLLGPAYLVFFADLQITAGMVWVAFLAVAAIFGVLWFVEPLILGSAAMYQAFNISNKLV-GSKRGDLAAVMAILSLLIFVGFLGTWLVSLVPVEVIEVARLYIMSLMGAVLVQAIVSMRN---VRATVVALGLAVVIQLLVVPAFPQLGMFATAVVVISSIIINWVVRDRRGQVT 247
4 -3.700PB007011 gi|160888195|ref|ZP_02069198.1| hypothetical protein BACUNI_00603 [Bacteroides uniformis ATCC 8492]gi|156862330|gb|EDO55761.1| hypothetical protein BACUNI_00603 [Bacteroides uniformis ATCC 8492]  ali follow..  6  19....GEKTEPLFFTSLCDKLLDENGGEEEWDVKTIPQPDIPEEKPSMADRGLYKNKKKRVKGKKDKLQPEVQGQPPLSWIRLSRKKLNEGVDE-------------AWAVFDKDEHPARKDAFEEAEKLIDDKEYY-----LLLHFEYLYHPFH.......................................................................................................................... 161
5 -3.610PB009661 _Gut.Meta.Jp.0000785_ gi|162567239|dbj|BAAU01000237.1||2 (- 3549:4008~0 complete)  ali follow..  11  2.....SVREGELLDEAVDFCRKRGLEFYAVNSNSADMYIDDRNDWGVIYEMVHNRWSYNRYLNEIHDFERSQKVS......................................................................................................................................................................................................... 92
6 -3.500PB028090 gi|167758043|ref|ZP_02430170.1| hypothetical protein CLOSCI_00381 [Clostridium scindens ATCC 35704]gi|167663940|gb|EDS08070.1| hypothetical protein CLOSCI_00381 [Clostridium scindens ATCC 35704]  ali follow..  9  37......................................................................................................GGIFCFLIVPA----ALTVYFIAIYVGAANGAEWALNNPTYVHMNLYAATAGCIGFMML--KYKWKIGKTNWFKVFPFVIVAINILIAVVSD-LYGGWWNWVNGIAGILNI............................................................... 173
7 -3.480PB030138 Q7MX14_PORGI/1-113 PB030138; Pfam-B_30138;  ali follow..  8  3LGSFYKQRKPRSFDHKPIYYDQRR-----DELEKRIERIRREVEQEEQAELDGQSSSHDYSGYRPRIRGTFVEGTQHLKERQLQGETQSTRSGRTLRTLALLIAVCLLSWLVF................................................................................................................................................................... 110
8 -3.180PB036876 Q56VH6_BACFR/1-141 PB036876; Pfam-B_36876;  ali follow..  11  53....NGFTDGEIYGQAVHYYDENEIEVGKPIQCQVAVNHVVELTAEEKAEARQNAIRQYQDEEVRRLQNRNKPRTATKATVQEVQQPSL........................................................................................................................................................................................... 137
9 -2.810PB044572 Q8A533_BACTN/1-343 PB044572; Pfam-B_44572;  ali follow..  12  119.......................SVWVKLAHTQEEQGWIRETELKESFV---------PTDS--------------------SQAIHFFSDTHASYFMIIFALFVGVYLFRAFRRKQLQLVYFNDIDSVYPLFLCLLMAFSATVYESMQVFVPDTWEHFYFNPTLSPF--SVFLLSIWLFLIVALAVLDDLFRQLTPAAAVFYLLGLMSSCIF............................................................... 284
10 -2.770PB083081 gi|160890648|ref|ZP_02071651.1| hypothetical protein BACUNI_03093 [Bacteroides uniformis ATCC 8492]gi|156859647|gb|EDO53078.1| hypothetical protein BACUNI_03093 [Bacteroides uniformis ATCC 8492]  ali follow..  13  2..................................................................................................................................................................................................................................KKTIFYSLFSALFMLTSCSMFEIDNYEEPSETIWGEVV............ 39
FFAS is supported by the NIH grant R01-GM087218-01
1 4 8 3 4 1   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Jaroszewski L, Slabinski L, Wooley J, Deacon AM, Lesley SA, Wilson IA, Godzik A. Genome pool strategy for structural coverage of protein families. Structure. 2008 Nov 12;16(11):1659-67.