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Query: [O] COG4934 Predicted protease, from COG1018

Results of FFAS03 search in HGM_OVER
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MKIALSAAIVLVMLFSAVYVAFNSNAGQTNQNSLNSLFSQPLVKSNDNIAKTVEKAGFKPYVPVNGSMEMNVIIGIIPNNLNELENYATEISMPGSPLYRHWLTTQQINSMFGNYQGVETVSSYFSKLGFSVQVKTPFAVAISGNASMMESVFHTTIYYFTNKNGQVLFSNLNSIELPGSVARYVLSVDGLSNFQMTTNPVYPTLSDYTSSGLIKNFEPLSSGTQSYLNHSDVVGFYAKKYAWVQLPLTNGPYPGSNVTGYTPPFQALFPSDLPWIYNIAPGLNGTSSTPGANGTGTTIAIVMGTGYINATLAYPAWNYNDMLKYGKEVFDNPSQILSRVTYLNAPGITHSPPPDPSPSFYVPYTDGYLGEFTLDTQYSATVAPDAHLDIMAIPSLSTVALDNAYITLYELPNTPQVITNSWSGSEDSWWNMYGPYWQSADLMNLLFELLSMKGSTIVAATGDSGGYDGYTNMISGEFPGTSPWVTGVGGDQVTMFNNTGVEFPVTGNYSRFNVTFGTANYSSLPPYYWSNLRLNIVNIGLKHNNGFTQTYWDNNQYVVVNGAPEVISTGAGSAALSIFFKQPWWQHGYSVPNTGRMSEVEVSAEAGFNQTELVDGMWGSWFFGGTSEATPTTAGMIADVISYLNATIHVNYLGDINPLLYEIGNEYMQNPGKMPDPYFTVSNGTNSLSALMVNDSYTLDGPQNYPSNYYTTDNGYSMLTGWGTINVGNFKIDLEQFLTQPFNVTEDNSTGTGTPFYGNFTESTYITMGQPAGLQYGTQYLFNVSGSVSGLTNIPKNLNLTFITSNGEYNLNNSNKPGNMHFAYNAGLLKIYSDTFNTTGFLEVNGTFDHRLAYSFTWIGSKQIANATNNISVEKNMSVSIAYPYLMAGFPAFAYTGLFNGTAGYFATYVPPIEPNMQIVNVTYKGKPVYNALVLLTYKNASNEIKNLTFLRQYAISYSFTNLNGSAYLDTWNVAVDTKAYVYVVYSGMVKESNFTLTPQSTSSILFNNSLESILLPYYNLLPVFQGQYLPFTVNQENAEVALYVPGSLNFYGPSTPTTVIPSTITNTNAKGFVNFKIPNWLPPGSLLYLGITNSSQPVYSAANGLILDHNVSYLPVYVAGSGPSVMLASNALTNIFGVPVVTPTTSFEAVYTDSLSPYGGYVNYMWYSVDGMTPISFGQDGYAVAAASQTQIFGLNSSIPSGLNTLYVYFNDTLGLTYETSMEFYFNASIPTPSLMLSSPSYYEHGNFSVSYKDNLNPNLTILNELYISYNGNIIASEPITTSSGVLQINGNDLPYGILNLTFTIETANGQTNETSITVMNLPADEYYPTVNIIAPVTGSSQTGSLNITFTYTGFDDTVILYVNGSSGNVITANVTGKNLYTITEGKGSSSLPAGNYTVTVLVISKDGQVAKQSANFDLKAPVVPPVQSSIIIEYLVIGIVGGLIVGSLAVVAVMRRHLast
1 -5.820PB083081 gi|160890648|ref|ZP_02071651.1| hypothetical protein BACUNI_03093 [Bacteroides uniformis ATCC 8492]gi|156859647|gb|EDO53078.1| hypothetical protein BACUNI_03093 [Bacteroides uniformis ATCC 8492]  ali follow..  10  29.........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................EPSETIWG--EVVDEATGKRVLTDQGSEGIRVRLTELSWGDNVQHNPDFTFQNTKIFKGEYNVRIDGPFIPLVRENTDGTLLHDGSVNTEISGTTKVKFEVQPFLNGVIKAQVRVTRGV... 162
2 -4.540PB003645 Q65HI2_BACLD/1-230 PB003645; Pfam-B_3645;  ali follow..  20  108...................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................DILETIIGEDVSIVVNVDATSLKIFEKNRKTQETST-----NETDKQGGKRTVSIVIIKNGD--KETPVVVQTKKPDIRGVLDNVQIKKTIIEAVTRVLVPS---VAVAPKK 226
3 -4.510HGC00522 gi|163636101|dbj|BABG01000172.1|3.0 TMP00580;  ali follow..  9  4......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................NYKRQRMNIFDIAKQNQEKAWQVIKNTNIIQIWEDAGAKILVGSLRTGLLMKHRDIDFHIYSSPLNLTDSFQAAENPSIKRIECANLLHTAEACIE-WHAWYQNEENELWQMDMIHIREGSRYDGYFEKVAISEIMTDEIRETILRGVEYYAVIR.. 177
4 -4.490PB007740 Q89YT2_BACTN/1-193 PB007740; Pfam-B_7740;  ali follow..  6  1MKTKFIYVVLMALFLGSQMTLSA----------------------QNEENKERKQRPTPEQMMQMQTNQMVRALMLDDATAAKF------------PIYEKYLKEARKDAAQGTEANTAKETPKPVMTDAEIAKMLKDQFAQSRKMLDIREKYYNEFSKILSQKQIMKIYQQEK-SNMNKFRKEF.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 163
5 -4.190PB000119 Q6KIT1_MYCMO/1-381 PB000119; Pfam-B_119;  ali follow..  15  198..............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................SSIFLSFISIFALTITFAYNSTFLNLAQI-------RINTIRPNPNPNPNEIFNFDLN-NG-TVEAIWFLQSKMELTDTATVIIINN-TAYVNINKNSVKHNNFAVNYLKSEENGLFVEKFFKVEVFSPKIPALY--FVVNNSTKNIFSSVGISSLST....... 365
6 -3.960PB017610 Q11T14_CYTH3/22-188 PB017610; Pfam-B_17610;  ali follow..  9  4.........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................LGKIVFGLGIAVCLFSATNSIAQVKTHSSLRAE-----------NLEVILVKDIQHISDTTHHTHAHDPHKSSYKILHVNFMLVSSDPVTGYKSVMMRLIDPHGTPYTFKVSTKLDGQPLKID------LHIIELYVDGLKIGEEHFV...... 166
7 -3.800PB011023 A7V2G7_BACUN/1-167 PB011023; Pfam-B_11023;  ali follow..  10  12.................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................SIFKALALCLFAAVSFTFVSCD-DDMDIQQSYPTVETMPVPNKVTKGQTVEIRCELKKTG------FANTLYTIRYFQFEGEGTLKMKFRLYYTAQGDEAHNFIVVVEDNFGNSYELEFDFNNRN..................................... 148
8 -3.760PB009233 Q7MX23_PORGI/1-175 PB009233; Pfam-B_9233;  ali follow..  6  1.....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................MGAAVRKQVRGAISFFLVALGICLAVSCTYRKDERILYRQVPHGRWQKRDVLDYEILIPDYTRSYSLELLIHDNRYEYRDLALAYEVSVGERLIFADSVDLTLADKFPYSGLYKIELKHNMVPTLSGITVG-IRLTEGRDSP 167
9 -3.670HGC00933 gi|162753228|dbj|BAAZ01012194.1|2.0 TMP01261;  ali follow..  11  18............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................PALRGHIQYFATSADHEGRAAIRMDGVEVLRSNYYTYFENVWTKFHHLRSTTLKD-AIDRSHAYALEQGTFDQKAFYEAFGIFDNQSIEKSLVSKNPLVRIL-ALLLGKRRLLALEES. 146
10 -3.640PB009510 _JGI.0345302_ 2004041369 [Human Gut Community Subject 8]  ali follow..  9  77..................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................EKRDYHSPMTPYIMERYLENATGFTVHIADCHDAGPLKYKPPHPNVFKA------FFNGDGTLDSKKVRKLIDKLKESHTTYFVNDYSMFEIVARRFDGSELWDGSEYEMRLGVKYKEGEFRIAETLDIERMTARAKVPLSEK-DGSVPM-------DGNKTTANIKIPVASISESYGNATCTVKRNL--YFDGKMNGSRLLNSLNRKE 329
FFAS is supported by the NIH grant R01-GM087218-01
1 4 7 8 6 2   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Jaroszewski L, Rychlewski L, Zhang B, Godzik A. Fold prediction by a hierarchy of sequence, threading, and modeling methods. Protein Sci. 1998 Jun;7(6):1431-40.