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Query: [S] COG5427 Uncharacterized membrane protein, from COG1018

Results of FFAS03 search in HGM_OVER
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MEFGVVARWWVFFGVLLVAGLPVASRLLPDAPDRGASVAMPLSLVVVTLATLWVGQVAYGQLVVGGVFVAVLAAAAWLARGGVEIPRKPLLEVVGVFTVAFVFLIVVRAWADGVQPAGGEQFLDFGLLQALDRAGQLPPRDMWFAGERVVYYYGGQLMASIGAHLTDTAPRFAYEPALAGVYAMGCTAAYGLASTIAAGNGGESRPVGVPTAIGGAGVALAVVVLATGVNWLVVAVPAAAAAVVVTRPRRVRAGVLGAFAFGFASNLGPVIRLLAARVDVVRAAVVAAGINADRRPAITPEAFDMWHASRFMETGLNEFPLFAYLNGDLHAHMVSVPVLFVAVAVGVAYYRTPARQRRRRWALLWGGFPVAGAAILTVNTWSLPTVFGVAALAVALADPAPATLLPTGVQRWTRRESAVGQSVQRVLLAVGVAAVGGVLAVVIAWPFVQNVLLAGASNQHLAVLPVPSQAGALVFVHGLFLAAFGAYFVSRVATSVAGWVVAAAAAGAAVAVAVAVGPVVGGVGITAVVLVGPVLGAAWWLRRRNAAGVECVLVAAGAGLVVLVEYVYLADAASYERFNTVFKVYAQVWALWSVAGGVALAGVSERRASTGGLGAVFVVGLVVAASVYGGLAVTTHAANADDASLDALEYAGNAHPGEAAAARWLGDRRRGTRIVAAPGVDPYTWQNPAASLSGVPTVAGWAHAANYHSQAAWEQRVDDIGVVYETTDAASRAAILEKYDVTYVWVGPVERARYEIPDLSADPGIEPVHRTPAVTIYRVTDDELVAPRSGPITVTTTPQAATATAPGAQTARSPARFVTVTSSASTAVTSSQWGTKLRFSLast
1 -6.310PB036876 Q56VH6_BACFR/1-141 PB036876; Pfam-B_36876;  ali follow..  10  1..........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................MKTTDHFKRTIQMYLEQRAAEDALFAKN----------------------------------YRNPAKNIDDC-----------------VTYILNYVQKSGCNGFTDGEIYGQAVHYYDENEIEVGKPIQCQVAVNHVVELTAEEKAEARQNAIRQYQDEEVRRLQNRNKPRTATKATVQEVQQPSLFD 139
2 -6.130PB046158 _JGI.0336690_ 2004028347 [Human Gut Community Subject 8]  ali follow..  10  1........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................LQEEVNQKVISLSIQGVKITASVLKAAVHGKQTI------------KQLNAQGVQLSNIITDENIKSFDRVARKYGIDYSLKKEVGADP---------PKYLVFFKAKDVAFREYAGVELKKKQVKKPSVRKKLQKSVERKAKHRQRVKQRQKSRGQE.................. 186
3 -4.530HGC00422 gi|163631722|dbj|BABG01004545.1|2.0 TMP00397;  ali follow..  9  35..............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ILHHTYEYTVREDIVMAMEQLELTDQALLDSPTPLADVYRYFEKLETGHMDVIRDSIENRADDVCRAKEELRTTPIYPHSAAYQYRASNNVNRQEAAVREHFDGMSHDAAKGVIETYGVSMVLSNTVQLQRYSRRNKEWAKTIPNDNPETVRCGYALNSHP-AVLDGFIDLVREEQQRSRTQREKLEPSRPSVRDKLKQELPAHKSAAPKKREPER.. 274
4 -4.460PB064361 Q64PJ4_BACFR/1-580 PB064361; Pfam-B_64361;  ali follow..  11  1..................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................MKIERLFIYCLLAGTSLLASCNSEDMTDNPVETLSEGMYPLTFTAMQGEVVAT--QTRVSDYDDTDGKHKSKWDGGEVIGVKDGKPTTSTSNIPAYWQSTASQ-----TVYGWYADISLTGQDNTGNKFPYVLKGVSSKQYSYKENVQLNLEHQLVKFLSDAKVFFYGYPTCKNEYGTVIPQGDKTYLATRKVGDYYTPDTKTSNNFVKIEVYGLTYYIELVKGTVYTYT 259
5 -4.020PB044380 A7LRP7_BACOV/1-223 PB044380; Pfam-B_44380;  ali follow..  5  1.........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................MGTIVYLSIRLACACYILYKVCGQKKKIREICDLLYTKLPPVKEKELENVLSEPGGESGIMGSTCFVYLDEDAGKSVAPYMSQPLETAADFIGEEEDVAEEEVECKLPLEEM----MLKEEQEELDGTYPAVDAVSRVVTPDDLDNAGNVLFKLNDA------------DKDEEKSLRAALTLHTIRETDLFEIFSSQVENKNVIDSLMGKYLDGNGNPLSVRKTKSVVPVSDGWKQ.................. 222
6 -4.010HGC00683 gi|163310582|dbj|BABD01000118.1|4.0 TMP00861;  ali follow..  7  1..................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................MKTLKITFVMLMTALFLVLPSCSKDDVNVTLTPSEEVVNAFQQKYP-DVKNVKWEILV--------GAYEAEFIYSGTYSENGQHIVLDKVEAQAYITQGGKWVRSEFDVTKDYQDSSSLVVPRAVRET-IAA--------------KGKKVDDVKLFDWSDRNDYFYVE............................................................ 146
7 -3.710PB000790 _Gut.Meta.Jp.0111831_ gi|163310496|dbj|BABD01000203.1||3 (- 2591:4589~0 complete)  ali follow..  11  219.........................................................................................................DYCSGKARIYFAPWE--SYFLLAEAAEYG--------WISNITPKEAY------------LGIRSSFEY-------FGVSEYADQYINSTTRNRLGTSVAFDDTVEPTSEVMTYRDGYTNTDQIQEVVYNYPTASKTLYGKAMNDHLTKIITQKYIAQMPY----------------------------------QVLEIWNDHR------LGLPFFE-QQWDFYPQRMRYP-------------TTLDNADPENYQKAVELLG---GS-IITPLW........................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 436
8 -3.460PB021133 Q64YN4_BACFR/1-310 PB021133; Pfam-B_21133;  ali follow..  7  1.................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................MHIDFALPSNGTYNNAGSSRQLANYLEHEDLERMEKGLYFNLTENNIYKSKVIKDIDSNIGQLLKTDAKFYAISEKELQAMGNTEHEQAESMKRYIREVFIPEYGLSEADIKNRSHSDNELNMHCHLIVSRKDQSNKKKLSPLTNHKNTKKGPIKGGFDRKSLFQ.. 186
9 -3.430PB023339 Q8A4U7_BACTN/1-171 PB023339; Pfam-B_23339;  ali follow..  6  4.............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................TVLFRMMVLVAMVVAGIANTELKAQDNNFITNEEKVDDLVVSKVIYRLDGSLYRHMKYDFTYDDQKRVTAKE--SSTEKWIPY--FKIDYAYSSNEITLVYARWNNSHRAYDDSVEKSVYELNDANMPIAYKWNDYKWIEESAGNWAMNIQTPVTDEAD............................................................ 166
10 -3.370PB007147 Q11UU2_CYTH3/1-245 PB007147; Pfam-B_7147;  ali follow..  7  14..............................LKEYGKNIQKIVDWIL---------TIEDREQRTRYANTCVELMRQLNPGVRDTEEHTTKLWDHLFIMSNF------------------KLDVDTPYPMPDIAVLGRKPERVPYNHNKLKYKHYGKNINLLIEQAILKEDGAEKEDAIIYLGRLM............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 141
FFAS is supported by the NIH grant R01-GM087218-01
1 4 8 3 2 2   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Li Z, Ye Y, Godzik A. Flexible Structural Neighborhood--a database of protein structural similarities and alignments. Nucleic Acids Res. 2006 Jan 1;34(Database issue):D277-80.