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Query: [I] KOG1683 Hydroxyacyl-CoA dehydrogenase/enoyl-CoA hydratase, from COG1018

Results of FFAS03 search in HGM_OVER
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MLSRVVHRSSSVFRTNLSFRLFSQSAFAVHSTHRVEKQGDVAVMKIDLPNTTENVLNKALFAEMNETLDRLQSDQSVKAIVVMSGKPNSFVAGADIQMFKAEKTAAGVSNLLREGQKQLLTIELSQKPIVAAIMGSCMGGGLEIALACHYRIAVNDKKTLLGLPEVTLGIMPGDGGTQRLPKLTTVQNVLDLTLTGKRIKANKAMKIGIVDRVIQPLGDGICTSTETTHKYLEEIAVQSARELANGKLKINRDKGFVHNATQAVMTSKFVLDNVILKMAKNKLIKLTNGNYPAPLKILDVVRTAYLDPKNGYEAEAKAFGELSQTFQSKALFGLFEGSTNAKKNKYGKGLPVNEIAVVGAGFMGAGIANVTINKGIRTVLLDANQAGVERGQNHVATHLNRQLKRQKISKLEREKIYNHLVPTIDYSAMKNADVVIEAVFEDLPLKHKVIRQIENVVGPNTIIASNTSALPIKDIAAASSRSDKVIGMHYFSPVEKMQLLEIITHDGTSKETLATAAQLGLKQGKLVVVVKDCPGFFVVRCLSPMMSEIVRLLQEGVEPSELDKLTTKFGFPVGAATLADEAGLDVAEHVARYLGTALGPRVHGGSVDLLSELVRAGHKGRKTSKGIFVYGDGAKGSKKVNQEAAKLFEKYKLTPIKSVSSPEDRQLRLVSRFVNEALLCLEEGVISSPSDGDIASVFGLGFPPFWGGPFRFVDLYGAGKLVAAMDRFAGVYESVQFEPCQLLRNHAKSGGQFYSLast
1 -3.510PB000790 _Gut.Meta.Jp.0111831_ gi|163310496|dbj|BABD01000203.1||3 (- 2591:4589~0 complete)  ali follow..  11  236..............................................................................................................................................................................................................................................................................................................................................FLLAEAAEY-----------------GWISNITPKEAYELGIRSSFEYFGVS-------------------EYADQYINSTTRNRLGTSVAFDDTVEPTSEVMTYRDGYTNTDQIQEVVYNYPTASKTLYGKAMNDHLTKIIT-----QKYIAQMPYQVLEILPFFEIPANESDLIGSDMVNVLKKDSWKN-----GQQWDFYPQRMRYP---------LDNADPENYQKAVELLG---GS----DVIITPL......................................................................................................................................................................... 435
2 -2.890PB037276 Q24TM0_DESHY/1-190 PB037276; Pfam-B_37276;  ali follow..  12  2........................................................................................................................................................................................................................................................................................................................................SNIEQAYRGYGFAGRGQKNGCTVYQLKGEGGSGE----MVCYDIAPGIQMSFNQLTMDSTFQSIAPVKKFLQDYCIEGCYEVEYQNGTVSFLGPLRKYRGVTEVEKAQHTLSAGFPQAEINLAGIVNELCGKEQSLLVKSREDVERIFGKLSEVDERIQAPYY----WIKTMEL............................................................................................................................................................................................................................................................. 190
3 -2.780PB003645 Q65HI2_BACLD/1-230 PB003645; Pfam-B_3645;  ali follow..  9  43LVSQIFSSEPSQEPAADQPAASQKATSESTVQSGEGEKEVFKPASDDKPKESIQDYEQEYENQLKDILETIIGVEDVSIVVNVDATSLKIFE-TSTNETDKQGGKRTVSEMSSDEEIVIIKNGDKETPVVVDIRGVLV-GVDNVQIKKT---IIEAVTRVLDVPSHRVAVAP....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 224
4 -2.270PB000119 Q6KIT1_MYCMO/1-381 PB000119; Pfam-B_119;  ali follow..  15  198.....................................................................................................................................................................................................................................................................................................................................................................................SSIFLSFISIFALTITFAYNSTFLNLAQIVRINTIRPNPNPNPNEIFNFDLNNLPIENGLLTVEAIW--------LQSKMELTDTATVIIINNTAYVNINKNSVKTGRDFPLLGLEVFSP--KIPALYFVVNNSTKNIFSSVGISLSTNNPKLIFTFTFDNGF........................................................................................................................................................................................................................... 380
5 -1.870PB202086 Q8G498_BIFLO/2-200 PB202086; Pfam-B_202086;  ali follow..  10  37..........................................................................................................................................................................................................................................................................................................................................................................LVAAVCAVILVVAGIIGWNAYSGAKLAEAKEACVTAADTV-------RNNANEYNALLNGDAADAAAVKAEQVKDS---------KTVESLGKELKASAPEYEGCVAENAQGLDAAAVKLNEQADWYETHEKSLSKAVRAVVESKAAKRLDDAKTNLTAKLDEASKLLADSDGKVADN....................................................................................................................................................................................................................... 198
6 -1.760PB044380 A7LRP7_BACOV/1-223 PB044380; Pfam-B_44380;  ali follow..  6  41.................................................................................................................................................................................................................................................................................................................................................PVKEKELENVLSEPGGESGIMGSTCF----------------------------------VYLDEDAGKSVAPYMSQPLETAADFIGEEEDVAEEEVECKLPLEEMRMLKEEQEELDGTYPAVDAVSRVVTPDDLDNAGNVLFKLKSLRAALTLHTIRETDLFEIFSSQVENKNVIDSLMG............................................................................................................................................................................................................................................. 195
7 -1.760PB007733 A3U921_9FLAO/1-209 PB007733; Pfam-B_7733;  ali follow..  10  42.............................................................................................................................................................................................................................................................................................................................................................................................................ILNKIKFTSDLERRRYLILRRKTRKVWPYA-LSELNARLASI-KSKSERRKYTKIVQKYIEEQ--FAAELKKLTRTEGQILVKLIHRQTGVTTFQ------LIKNLRSGWRAFWYDTTAGLFDIELKSEYNPVNNREDFLIEDILQRSFQRNILDNQPSVLNIDYFEASSKW.......................................................................................................................................................................................... 209
8 -1.600PB019388 gi|83589066|ref|YP_429075.1| Radical SAM [Moorella thermoacetica ATCC 39073]gi|83571980|gb|ABC18532.1| Radical SAM [Moorella thermoacetica ATCC 39073]  ali follow..  7  1.............................................................................................................................................................................................................................................................................................................................................................................................................................................................RADEFGYLFLDRPPYQVLA--SSAITYEEMLR-LHAIEGLLKY-YGNSHLADHAFAYLAATAFDGSYFAIYEALAAWWEARGLLRRGHSQRDLFNHLASFAIHLARGIAT---------------------RVTVPPLPGYHDSILEINSHGDTPASGAEHSGCARNLTPAQLDRFYQ----FDCLCRDRSRNFPGWMPPSPLTEEERSNWMARITTPRSMEKYMPGLVKESPANLRRHGFIELFPCHPIVFFYYG...................................................... 239
9 -1.540PB005346 A0R807_PELPD/1-258 PB005346; Pfam-B_5346;  ali follow..  11  1..................................................................................................................................................................................................................................................................................................................................................................................................................................................MTDSLFWAIDIKNQFMSQINQTTSGNFYSHRNITDQVLENFTDALDCLTAHLMLECSEVLAGVKPANLISIVNRTRPCGRNLYLLWQQHHTDLAQRLNNLNFMVSLLLLCYDHV---RLEHHLSHPGIRTLLHKAGYKDDADCEGMLLELRSRIGGNNSFPHEIGLFIGYPAKDVAAFMGLVRLPFTCQR--WKIYGNPARSLA..................................................................................................................... 212
10 -1.390HGC00522 gi|163636101|dbj|BABG01000172.1|3.0 TMP00580;  ali follow..  12  1..................................................................................................................................................................................................................................................................................................................................LQTNYKRQRMNIFDIAKQNQEKAWQVIKNTNIIQIWEVGSLRTGLLMKHRDIDFHIYSSPLNLTDSFQAMARLAENPSKRIECANLLHTAEACIEWHAWYQNEENELWQMDMHIREGSRYDGYFEKVAQRISEIM-------TDEIRETILRLKYETPETEKIIGVEYYQAV..................................................................................................................................................................................................................................................................... 175
FFAS is supported by the NIH grant R01-GM087218-01
1 4 8 3 4 4   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Ye Y, Godzik A. Flexible structure alignment by chaining aligned fragment pairs allowing twists. Bioinformatics. 2003 Oct;19 Suppl 2:II246-II255.