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Query: [L] KOG1978 DNA mismatch repair protein - MLH2/PMS1/Pms2 family, from COG1018

Results of FFAS03 search in HGM_OVER
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MSQNKIERISKEVAERLTTAQVVVSLSSAIRQLIDNSIDAGSTIIDIRVKNNGFESIEVQDNGSGIEARNFDALCKPHSTSKLTQFSDFDKLATLGFRGEALNALCTVSSVSIFTRASDTEIGTRLTYDHSGNIICRQSAARELGTTIIVNKLFETLPVRRKELERSQKREFVKLLSTVQSFALLCPHIKILCTNNINGKKTNLICTPGGTTSIQDVVANLFGIARKIENSKIGSGLIPIQQNQPDVEIMTIHSVPMEEMHFFDLFKIRGFVSSCEHGCGRGTSDRQFVYINNRPVEYSRVCSVINDVYKQFNKKQYPIIVLFIDVPPEKIDVNVTPDKKTVMLEKERHLLAVVRASMMKTYLKIVGSHSTVRSSVEDRRIMNLSQQSFSNASFMSSKSSTPDDFNNTTLNSTYPEDSLLNTSDLLKQRKENRSPPAKKSCPMIRRTEPFHSVPSTSNSRTQRLENFSFTMEPKRVEVSKKIPSKSDKKLTDEELRSAVIEENPLKKAGEIDDIEILEQSQESQDVNESQCSQDSQTSQNSRVSYFTLRPQQKIKFSMKLLREAYSPKTDETDDNTEEAEVSAEKDVLNEITTKINKEENDDAERQLSRSLTKDDFSKMKIIGQFNHGFIICRLRGHLFIVDQHASDEKYNFERLQSSAKLTKQPLFMPTALGFGAVQELIIRENLPIFHANGFDFEFSENDGCIKTFLTARPELLNQQLTNSDLEEILAVVSQYPNQMYRPVRIRKIFASKACRKSVMIGKPLNQREMTQIIRHLAKLDQPWNCPHGRPTIRHLASLPDRAEFELast
1 -2.100PB155142 _HOMD.0127537_ bfor_c_1_1790 Tannerella forsythia ATCC 43037 [677748 - 680894] ORF  ali follow..  17  7...SVLNLINPEDIESQ----------TILK-------DAAATALYGSRGANGVVLITTKSGRRGKTHIAFTAEYGTSDFATPHALDYMDAGQYAQYTWESLKN............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 90
2 -1.970PB000119 Q6KIT1_MYCMO/1-381 PB000119; Pfam-B_119;  ali follow..  13  202LSFISIFALT-----TFAYNSTFLNLAQIVR----NTIRPNPNPNPNEIFNFDLNNLPI-ENG-------------------------LLTVEAIWF--QSKMELTDTATVIIINNTAYVNINKNSVKHNNNYLKSEENNWYLTGRDFPLLGLF-KIPALYFVVNNSTKNIFSSV---ISSLSTNNPKLIFTFTFDNG............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 379
3 -1.760PB017124 _Gut.Meta.Jp.0039711_ gi|162659581|dbj|BAAX01000024.1||2 (+ 385:1498~0 complete)  ali follow..  10  45LEDGNLVCLGA------AGGYITVALDQPIKNILGNAFYSANDPKYGDATIGGPGIVYVGVGSSPETAEWYELAGSEYYTTEMHRFEEIKTPDQITFRGARLPDNAVNYGGDGSDPDNPQYWVSYRY-DNVYTTFDLDWAVDSDGNPKHLDHAFIRI--QQCGWTGETSTEVGRITN.................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 298
4 -1.740PB009671 Q5LCM2_BACFN/1-111 PB009671; Pfam-B_9671;  ali follow..  9  3....................KVLVALTMVMGMGSAVAFAQEPVKLPAMEQNQQ----TSQDKFTKITVKELPQVVKSTLSKD--------------YEGTIVKEAFVAEKIIVTAIKDQSTEEITVLLNEKGEPVNEKD.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 111
5 -1.730HGC00711 gi|162743779|dbj|BAAZ01020484.1|1.0 TMP00907;  ali follow..  9  28...........................................................DERGAGTVLVVGVIAVLLAAALGVSGLIQAQAAAG---RSRAAADLAALGGATALSSIVAPEAASRVARANGAEVTTCSVTGEDVVVEVSVE.............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 120
6 -1.630PB060121 Q64SA7_BACFR/1-251 PB060121; Pfam-B_60121;  ali follow..  10  21LTQEMIEDLPLCILKEIGKGGYSPVLPMRVTNENGEVIESRS-RFAFIRMDSGEVDVVFSSPLECYNEEQQKQLLDGKSIIADVAMADGRRSKAFVQIDEETKQVMYVPTPIIARNLKVLAEVMHLGTVEVNGMQH--------GEPLTVAV............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 168
7 -1.410HGC00485 gi|163636056|dbj|BABG01000217.1|3.0 TMP00523;  ali follow..  11  3MNPNILNLMFFDRAVNAQRSQLLTVMADAVSECRT------AADQAAELNETGQ---------VGL-------LRLAEVWSAIRAKEGMGGLILEGTEAKILSDVVAQFYAYLSGCMFNDPVGMAIYAE.................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 112
8 -1.410PB144506 _Gut.Meta.Jp.0101058_ gi|162866171|dbj|BABB01003836.1||1 (- 121:946~0 complete)  ali follow..  15  1MKTKLVAVIALIFCAFMAEASKVEGNGNIITK-LGGNIEGRSASLKITIDENLFPLLSIKSNNGRLAIRIQDGTRIKPTQYVIESSKTLKYLKTSGFSEDQLEKISGSSDVKFPHNVKLRLG--EFSVSGSGDLVFADLDCKNLTSKVS................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 190
9 -1.370HGC00690 gi|162868815|dbj|BABB01001192.1|3.0 TMP00870;  ali follow..  13  1MFEYILREI---SVIAFLAGAGVVLVIGVVPRILRCSRIENIILIENVMICGVVNISSVLDTAYNLGFANMPKVPVSNICGNI--------IAIYGFVGCIAVALAEILHTPIIYKRMKLRAGLGI-------IVISMAIGKALGALY................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 148
10 -1.280PB004476 gi|139436894|ref|ZP_01771054.1| Hypothetical protein COLAER_00025 [Collinsella aerofaciens ATCC 25986]gi|133776541|gb|EBA40361.1| Hypothetical protein COLAER_00025 [Collinsella aerofaciens ATCC 25986]  ali follow..  9  46..............QVAYPNTIIVDVSFSNASSAATKVNSAWKHYKLTVTGDDFSTYQPESNEPIVDGEAAAKEIISHNEAEVDLDQDVDLSMSDTFDQKKFEKDLG-AAIDEFNEGRSGTFEANSSYDEQAG--KFTVEKARSNEKLNREHV---------------------IKYAELELASLAETVDLSKLGNDAYEPLNGTLTDDQIQAACNAANNFLGVNVTLKLNGEDAGKVD------GSSVLQWISFADPANPTLDTSQISSWAAELANGFNTVGSTRWWTRADGKQIDSSSLAKQVEDAINN.............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 349
FFAS is supported by the NIH grant R01-GM087218-01
1 4 8 0 6 6   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Pawlowski K, Pio F, Chu Z, Reed JC, Godzik A. PAAD - a new protein domain associated with apoptosis, cancer and autoimmune diseases. Trends Biochem Sci. 2001 Feb;26(2):85-7.