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Query: [E] KOG2380 Prephenate dehydrogenase (NADP+), from COG1018

Results of FFAS03 search in HGM_OVER
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MAETLITKPPLSLSFTSLSSMLPSLSLSTANRHLSVTDTIPLPNSNSNATPPLRIAIIGFGNYGQFLAETLISQGHILFAHSRSDHSSAARRLGVSYFTDLHDLCERHPDVVLLCTSILSIENILKTLPFQRLRRNTLFVDVLSVKEFAKTLLLQYLPEDFDILCTHPMFGPQSVSSNHGWRGLRFVYDKVRIGEERLRVSRCESFLEIFVREGCEMVEMSVTDHDKFAAESQFITHTLGRLLGMLKLISTPINTKGYEALLDLAENICGDSFDLYYGLFVYNNNSLEVLERIDLAFEALRKELFSRLHGVVRKQSFEGEAKKVHVFPNCGENDASLDMMRSEDVVVKYEYNSQVSGSVNDGSRLKIGIVGFGNFGQFLGKTMVKQGHTVLAYSRSDYTDEAAKLGVSYFSDLDDLFEEHPEVIILCTSILSTEKVLESLPFQRLKRSTLFVDVLSVKEFPRNLFLQTLPQDFDILCTHPMFGPESGKNGWNNLAFVFDKVRIGMDDRRKSRCNSFLDIFAREGCRMVEMSCAEHDWHAAGSQFITHTVGRLLEKLSLESTPIDTKGYETLLKLVENTAGDSFDLYYGLFLYNPNAMEQLERFHVAFESLKTQLFGRLHSQHSHELAKSSSPKTTKLLTSLast
1 -4.200PB003645 Q65HI2_BACLD/1-230 PB003645; Pfam-B_3645;  ali follow..  8  63......ASQKATSESTVQSGEGEKEVFKPASDDKPKESIQDYEQEYENQLKDILETIIGVEDVSIVVN--VDATSLKIFEKNRKTQETSTNETDKQGGKRTVSEMSSDEEIVIIK---DKETPVVVQTKKPDIRGVLVVAQ-VQIKKTIIEAVTRVLDVPSHRVAVAPK....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 225
2 -3.050PB005684 gi|160884252|ref|ZP_02065255.1| hypothetical protein BACOVA_02230 [Bacteroides ovatus ATCC 8483]gi|156109991|gb|EDO11736.1| hypothetical protein BACOVA_02230 [Bacteroides ovatus ATCC 8483]  ali follow..  6  58..............................................................................................................................................................................................................ENDWPEFLQRIIKAGSSPIQHDIMLLGALTALGACM----------------SRHVRCLYGGKYHHPSLQCFVVAPSASGKGILSYIRLLVEPIHDEIRKEVTIQMKAYKKEKAEYDAMGKERTKKEAPQMPPNRMFLISGNNTGTGILQNIMDSDGTGLICEAEADTLSTAIGSDHGHWSDTLR------KAFDHDRLSYNRRTDQEYREVKKSYLVLISGTPSQVQTFIPTAEDGSYSRQLYYY---DNEIDWEEIFTAMGLEWKEKLSVIKTHGIHTLQLTDEQKEEIDTVFSDLFERSSVANGREMYSFVARLAVNLC--------RIMSEVAVLRALESPQPYDITRWDVSISQEDFHAVLSLAEPLYCHATHILSFL--NTEISHRPNADRDYLFQKLGDEFTRTQLLEEAVAMGIKENTALTWLKR. 493
3 -2.800PB012991 Q2RHT0_MOOTA/1-175 PB012991; Pfam-B_12991;  ali follow..  14  28..............................................LKGVFLLRIAVVQGGGIGKHITARLRQE-EILALGTNAAATVAMIKAGANEGATGERAIAPRVEAITGSLAIILADAMLGELTPAMAA--------AIAASPARKFLLPINRSGVEVIGVTPE....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 151
4 -2.250HGC00870 gi|163286116|dbj|BABD01024572.1|2.0 TMP01154;  ali follow..  10  17...................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ETILLFHAPDKDTLLKIEMALFPLHVRLRRVAKEDYVQPLGALAGVKDIPRIEETYEGDELSDFSDNRLNQALAALRKSGAGTFPYKAILTPTNQNALQCFSEIRREHETIQKQLKGNKEQA................... 147
5 -2.030HGC00711 gi|162743779|dbj|BAAZ01020484.1|1.0 TMP00907;  ali follow..  8  29....................................................................................................................................................................................................................................................................................................................................................................................................................................................................ERGAGTVLVVGVIAVLLAAALGVSGLIQAQAAAGRSRAAADLAALGGATALSSIVAPGDPCEAASRVARANGAEVTTCSVTGEDVVVEVSVEAR.............................................................................................. 122
6 -1.980PB012771 _Gut.Meta.Jp.0094636_ gi|162817068|dbj|BABA01027641.1||1 (+ 249:636~0 complete)  ali follow..  6  64.....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ADELAALLESVQRECEEREAVLVREMAEVNEEMKGNEQMAWVQRMEMICGRVEEVVCEE 125
7 -1.770HGC00024 gi|162813637|dbj|BABA01031072.1|2.0 TMP01508;  ali follow..  6  17......................................................................................................................................................................................................................................................................................................................................................................................................................................ALAVSLVTTGCSDLLDKEPPSAISDGSFWTGEGDAMLALTGCYRFQTGWSHDATPQGLLYLDFAGGNGTEKENFSTLMASSNTVATNSNLRWYWGNAYTQINITDCPMEESKKEQWSAEVKCLRAYFFLNLAFY-----------YTDVPMPLKTLSVDE-----ANSISQTPQTEVYSQVEKDLKTAIDLLPVHYLRGIWRLPGGG........... 217
8 -1.500PB047024 _Gut.Meta.Jp.0098985_ gi|162869273|dbj|BABB01000734.1||6 (+ 5047:5650~0 complete)  ali follow..  8  33......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................HDMSKYSPTEFLVGCRYYKGYMSPNNAERADRGYSSAWLHHKGRNKHHLEYWIDMKMPIRYVCEMFIDRVSASKNYQKMIHPDTKAMLEYLLVMLSVKGEEYTYS. 173
9 -1.490PB007011 gi|160888195|ref|ZP_02069198.1| hypothetical protein BACUNI_00603 [Bacteroides uniformis ATCC 8492]gi|156862330|gb|EDO55761.1| hypothetical protein BACUNI_00603 [Bacteroides uniformis ATCC 8492]  ali follow..  9  1..........................................RQSEDSRHSKYVIRIICEGEK-TSLCDKLLDENGGEEEWDVKTIPQPDIPEEKPSMADRGKGKKDKLQPEVQGQPPLSWIRLSRKKLNEGVDEAWAVFDKPARKDAFEEAEKLIDDKKVNIAFSSRSF------------EYYLLLHFEYLYHPFHATECGERIDGKKVNYNCMTEKSKENACHGEKCINGYARLKKYWNETKTSQSTFPLIEKRLKAGIINAKRLRIESNS--CPIYDRNPYT--NVDKLVCRL....................................................................................................................................................................................................................................................................................................................................................... 259
10 -1.390PB017124 _Gut.Meta.Jp.0039711_ gi|162659581|dbj|BAAX01000024.1||2 (+ 385:1498~0 complete)  ali follow..  4  1.......ASAQAKQTVKVLEYCPAPGQFTNKLPEINNTMSAEERLKACEEQLEDGNLVCLGAAGGYITVALDQKGSDIRILGNAFYSA-----NDPKYGDATIGGSVEPGIVYVGVG-EYYTTEMHRFEITYYKPTVETGEIKTPYITIDNYIR------TASWTNPDGSKQTAEGWQPKNVYHKQSYWPAWEENDQITFRGARLPDNAVNYGGDGSDPDNPQYWVSYRYAADSYGYADAAPNSDNVYTTFDLD------AVDSDGNPKHLDHADFIRIQSGVLQQCGWTGETSTEVGRITN.................................................................................................................................................................................................................................................................................................................................................. 298
FFAS is supported by the NIH grant R01-GM087218-01
1 4 8 3 1 9   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Ye Y, Godzik A. Multiple flexible structure alignment using partial order graphs. Bioinformatics. 2005 Mar 3;