Scheduled maintenance will begin on May 30th, 2025. Server will be temporarily unavailable — learn more.
current user: public
If you have questions about the server, please let us know.

Query: [I] KOG2833 Mevalonate pyrophosphate decarboxylase, from COG1018

Results of FFAS03 search in HGM_OVER
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
    .   10    .   20    .   30    .   40    .   50    .   60    .   70    .   80    .   90    .  100    .  110    .  120    .  130    .  140    .  150    .  160    .  170    .  180    .  190    .  200    .  210    .  220    .  230    .  240    .  250    .  260    .  270    .  280    .  290    .  300    .  310    .  320    .  330    .  340    .  350    .  360    .  370    .  380    .  390    .  400    .  410
# Score Template Links and tools%idFirst MATEKWVFMVTAQTPTNIAVIKYWGKRDEVRILPVNDSISVTLDPDHLCTVTTVAVSPAFDRDRMWLNGKEISLSGSRYQNCLREIRGRAGDVEDMEKGIKIRKKDWEKLNLHIASHNNFPTAAGLASSAAGFACLVFSLAKLMNVDEDPSHLSAIARQGSGSACRSLFGGFVKWTMGSKEDGSDSVAVQLADEKHWDDLVIIIAVETSSTSGMRESVETSLLLQHRAKEVVPKRILQMEEAIKNRDFASFTQLTCTDSNQFHAVCLDTSPPIFYMNDTSHRIISLVEKWNRSEGTPQVAYTFDAGPNAVLIARNRKVAVQLLQGLLYYFPPKSDTDMKSYVVGDNSILKEAGLDGASGVENLQPPPEIKDNIGSQDQKGEVSYFICTRPGKGPIVLHDQTQALLDPETGLPKLast
1 -2.960HGC00921 gi|162841401|dbj|BABA01003308.1|3.0 TMP01242;  ali follow..  14  5...............................LLPNTDQARIRA------LKTAVVKGDMCDVYDLPVSLKTLGEARIFLSKFETAHSYYVHCYGEQSRNSKKHQANVKTARLYISVLNLAVIRMEIKESHKALYGLPVDNFSVPDLSSEASLAEWGQKIIEGERKRTSQGGIPIYNPTIAK------------KVHYDIFMEGYEKQKSLQSLTNRSLEQLASMRVQADRLILDIWNQVEAKFQDVSPNEIIGPEKNRIRRFFKICLSIHIPIFFWKS--------LQKITFRYGTCPCC-RCDA............................................................................................................ 269
2 -2.780HGC00962 gi|162759780|dbj|BAAZ01005693.1|3.0 TMP01305;  ali follow..  5  45......................................................................................................................................................................................................................................LSDDVWQEVDAFYKLDNCPIRNEFAEK-ALRQYCGRLHAERTGAYLPRALQGVLETLGVFGERLGRLLLKLAVEHNMTNHLLGGDMDMTRDEYSKMR...................................................................................... 141
3 -2.680PB019388 gi|83589066|ref|YP_429075.1| Radical SAM [Moorella thermoacetica ATCC 39073]gi|83571980|gb|ABC18532.1| Radical SAM [Moorella thermoacetica ATCC 39073]  ali follow..  8  2............................................................................................................ADEFGYLFLDRPPYQV-LASSAITYEEMLRLLKYYGNSHLADHAFAYLAATAFDGSYFAIYEALAAW------EARGLLRRGHSQRDLFNHLASFAIHLARGIATRVTVPPLPGYHDSGDTPASGAEHSGCARNLTPAQLDRFYQLLKFDCLCRDR--SRNFPGWMPPSPLTEEERSNWMARITTPRSMEKYMPGLVKESPANLRRHGFIE.............................................................................................. 217
4 -2.370PB011051 Q8A0P0_BACTN/1-227 PB011051; Pfam-B_11051;  ali follow..  10  41VIARLIDIRKAQQEYRSLHHGMYTEHFDTLIDFVKNQKLPFVMKVGQLTDDQLESGLTEKKAMAIINKAKKTGKYDEVKKNGLENFKRDTMWVAVMDTIYPKGFNADSMKYIPYGNGAIFEMNVKNDTAKSGAPVYLFEVKAPYETYLGGLDRQEIIMVGSIDNPNNGAGN---W.............................................................................................................................................................................................................................................. 227
5 -2.070PB000520 Q9RVX4_DEIRA/1-194 PB000520; Pfam-B_520;  ali follow..  11  1..............................MRVPRRSLLSGAVTLKRMPQPVTALLAAMITPAVLISGGTLIMSTSTRVGRATDRVRGLTSRFKQLVSAEGQNEPLAREEKRLIIRQLPR-LMRALQAFYTSVALLVLTSILLGLDGLFDVNTGSLPLLVALGGSVSLAYGALLL.............................................................................................................................................................................................................................................. 161
6 -1.710PB000119 Q6KIT1_MYCMO/1-381 PB000119; Pfam-B_119;  ali follow..  14  181..............................................................................................................KFTFTFKEIKFKKINFFSSIFLSFISIFALTITFAYNSTFLNLAQIVRINT-----PIENGLAIWFLQSKMELTDTATVIIINNTAYVNIN-------------KNSVKHNNFAVNYLKSEENN--------LTGRDFPLLGLFVEKFFKDDVEVFSPKIPALYFVNNSTKNIFSSVSSLSTNNPKLIFTFTFDNG........................................................................................................... 379
7 -1.680PB033130 gi|160880323|ref|YP_001559291.1| transglutaminase domain protein [Clostridium phytofermentans ISDg]gi|160428989|gb|ABX42552.1| transglutaminase domain protein [Clostridium phytofermentans ISDg]  ali follow..  10  5...........................................................................................................AKVSLEILNYAEFASVTELYTDEKGCVSITIGLGDIH-AVKDGFFAEAMGHVRTQEEITLILNDNLLSKDWVTDSWEMCEVEAPKDSVKYQFNLTREQQATNRSKLREAKLLRENRIESYYDEALAENVPDAKEILHLGNFMEIYRFLTVDGNNVDS------------NQDRLALLKTLK--------------------------VKDYKDVTASVLEDHLKVRESSYKYRPVYKDNIAHEDSIVYKESIEFNDSCVYNDSIAYEYSFA---MEYIVCPRIY...................... 250
8 -1.670PB025553 _HOMD.0078651_ pint_c_1_4510 Prevotella intermedia 17 [1755134 - 1755736] ORF  ali follow..  14  22.......................................................................................................................................................................................................IEDIIRVYGCSLTRIRKEYIDKFDYTDEQKEEEEDWFGDLVRMMNQEGCRENGHLVMQALTELHTQLLASSKFPFY-SAEYYRVLPFIVELRGKTK...................................................................................................................... 121
9 -1.490PB048420 Q64S71_BACFR/1-165 PB048420; Pfam-B_48420;  ali follow..  9  3...............IQFVIVRSENANVNGTYVDVSDPS-------------------------------VSGEDDFRLVDPDSSLTRKEYEFRGERFYLMPQFYGNGWLALTLQSVEDETEYIVLSVNLESMDALDLPDRTFIDVNHYPDAMEFLETNNLATYSYKRRSGFVEY.............................................................................................................................................................................................................................................. 140
10 -1.450PB038151 Q8A4A5_BACTN/1-178 PB038151; Pfam-B_38151;  ali follow..  12  2.......................................................................................................ATQAIDATIFASSHPDIAKRTSISGLLISCVMLLIGILSFASTFELEDKSSTV------SMALMVFGTG---------------------------LFLLGIFRLFWKSKEVVYVPTGSIAKERSIFFDLKHMDKLTDLVNSGSFSADSKIKSEASGNIRM-------DVILSADNKFAAVQLFQ-----------FVPYTYQPVTAVHYFTNDAAAAVAAFLTK..................................................................................... 175
FFAS is supported by the NIH grant R01-GM087218-01
1 4 8 0 6 7   jobs submitted since Jan 1, 2011
Comments and questions to: webmaster
Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Friedberg I, Harder T, Kolodny R, Sitbon E, Li Z, Godzik A. Using an alignment of fragment strings for comparing protein structures. Bioinformatics. 2007 Jan 15;23(2):e219-24.