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Query: [R] KOG3518 Putative guanine nucleotide exchange factor, from COG1018

Results of FFAS03 search in HGM_OVER
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MCAAQAHQHCSTSVAGDRLLGSSTELAPSLLGIYDTLTNSFAAGGVAAAPTATSHESKASSSGDSTPKRSNSNCSSSSSTGSSTGSCSSVPTSDDQSASYTLASSSTHLGHQEPPAPLVVAGLRDEPDGAQLSRLVQRRSQESQIHGSSSSIASSGSSRRGSNIRILSPNVHRIITHSDIQPVEAVSAEALKQHQQQSQRSPTQGRYIKTGHSGTPPAAGSAPKLKLSHIPLSKITGKLSTQSGSELVSTFDSSNEYLNSVAFAAFEKSKPQDEDRTPTNKSVPGTPFHFDGHPFQGRKLTLPRYDSQQSIKLIEMEQLAATSAQLLHAKPATPGTPATPTPSATKAKEFVCSEPLSPVDIVDTINFDLVAQHMERLTLADPGDLDPRAELIEAVNKTLVNKPLVRSSSAACASTICSSPLLTYARTKSLGAKASTLGGGVPIKLPTAEQLAELEEANKLSAESLDRLTDIKPKFAARLSELARLNNRPLSSSSICSTSSSSSSGSDQLLNGKLMATSYLASVESLAESENELGDQHHPPAMSVLEKTCLEIVDSERSFVEDLGQVIKGYLQDWKERACLRVDELQILFANIEEIYEFNSMLLQRLINTGRDPGRIARCFIDLRDGFDVYTTYCTSYPEAISLLTKLLQATHTYSLLASTQKLLQHRLPLGSYLLKPVQRILKYHLLLDSLRKHCDVKEVVEAHVIMRQVAHNIDQVKRKQEQQSRVKELSGILDGWLGPELTVLGELRQEGLLMEQHNKQRLVLLFATMLIITKQKEDGRLQFKTYISQNNLMLSEHLPGEPTSFYVIPFDEPRHQIKLTARNRDQKRIWTQHIKGVMLEKLDIPMRAKELVYQLGNEEGECFPLGLast
1 -4.750PB025553 _HOMD.0078651_ pint_c_1_4510 Prevotella intermedia 17 [1755134 - 1755736] ORF  ali follow..  10  4...........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................AKELRKKSIAEYLL-----YMWQIEDIIRVYVRMMNQEGCRENGHLQINKVVMQALTELHTQLLASSKF----------------------PFYSAEYYRVLPFIVELRGKTKQVADRMARKNEANLKEIAANLGHSEVETCFDYGVMMLRLQKKEISRETETAVKEITTLIGMLSDYYQKDKTEG.............................................................................................................................................. 196
2 -4.350PB000119 Q6KIT1_MYCMO/1-381 PB000119; Pfam-B_119;  ali follow..  13  162..................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................VAPNLVKILNKNLPNLWGEKFTFTFKEIKFKKINFFSSIFLSFIS-ALTITFAYNSTFLNLAQIVRINTIRPNPNPNPNEIFN-----------FD-------NNLPIENGLLT-VEAI-----FLQSKMELTDTATV-----IIINNTAYVNINKNSVKHNNFAVNLKSEENNWTGRDFPLLGLFVEK-------------FFKDDVEVFSPKIPALYFVVNNSTKFSSVGISSLSTNNPK-FTFTFDNG...................................................... 379
3 -3.140PB032818 Q5LA03_BACFN/1-211 PB032818; Pfam-B_32818;  ali follow..  9  22....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................VEDFVSLTRVYITNIRFLVANFKRLFKQGGKLGLAEKSASRKMLMQDYGISESFFKEIDTSIKK-----NC--RTQNDVQAYLFMYQGFSSD---------------------------------LMMLMGNLMQWKFRMPAIFK--------KALRSMTE--KTVHDVCTK--------------TVWKADDVHKTAAAVRQYKERLGFSEQ---YVYN-IVLLAKKEPKH....................................................................................... 204
4 -2.860PB050904 Q64SA2_BACFR/1-230 PB050904; Pfam-B_50904;  ali follow..  11  41........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................NELINGQIEKQIKGQTQTALLQNSIATEFNQIHKWEKQYNSYLKTA-SGYASSLK--------ACTHLYNDGVRIFLTLGKLGKAIQNNPQGIVASMNM--------NLYIETATELVSVFTLLNDAVAKGSNENMLTGAE-----RSKTLWALNDQLSDFSRKLHLLYLSIRYYTFNDVWNNVTA---ARMALSHWHRAAA................................................................................................................................................. 228
5 -2.760PB162065 _Gut.Meta.Jp.0089312_ gi|162832207|dbj|BABA01012502.1||1 (- 0:1326~0 complete)  ali follow..  9  1.....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................LIGIFFQKTLKETVCEGAEVGFITITMEDV---DLATADALKRAAA---SMG--LESHRLSYEYYALSQRRE-THDVGLFEYDRRG------------------LRYHHLSVSWKHHPPVVTAETTVLNQYLDGHELADPVPPEMDRQFLEAIKEVSARRMISTYYLMGEGFSGAESGKS----MNLSLKQLCAMKRHVFLYARGACYHSFDQGSFGRKPGFIAANAGLLTKDIY-----LRSVHKHAPQKLILAAAGT-----PWYSRKAIIIDGQEQLIIFEQTVVMTLDALPQRP.... 284
6 -2.450PB007147 Q11UU2_CYTH3/1-245 PB007147; Pfam-B_7147;  ali follow..  8  10.....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................KGIVLKE--YGKNIQKIVD-WILTIEDREQRTRYANTCVMRQLTKLWD-HLFIMSNFKLDVDTPYPMPD--VPYNHNKLKYKHYGKNINLLIEQAILKEDGAEKEDAIIYLGRLMKRLYS-DEVIVEHLSELSKNNLQIDI................................................................................................................................................................................. 174
7 -2.420PB040621 Q8A865_BACTN/1-132 PB040621; Pfam-B_40621;  ali follow..  9  26.........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................HSKTVYAFGIAASFTDYFTDIQILDSAKVSKEGFLTHR-----LYSYQLKNYVEDNGLQQNSTCMIY------------FSENRKKLEKEATKILS-----KYKRNRNTTVTR-IDTDKFHFIKPE............................................................................................................................................................................................ 132
8 -2.370HGC00374 gi|162831834|dbj|BABA01012875.1|1.0 TMP00304;  ali follow..  12  15....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................IRDIRASEKRVVKEIFALSVDY--------DSKSQVAQSFFKSVQN-YAATGHTAPELKRADASKDNMGLTSFKGVKVRRGDVTVAKNY--THEEISTLNLIVNMYLDYAELQAKGHIPMHMADW-ESKLGDFLRFN---REVLENFGTVKREVAEKLALEQYEQYDTHRRALEAADDVDELTADVK.................................................................................................................................... 196
9 -2.330PB005346 A0R807_PELPD/1-258 PB005346; Pfam-B_5346;  ali follow..  8  21.................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................GMSQINQTTSGNFYSHRNITDQVLENFTDALDCLTAHLMLECSEV-----LAGVKPANLIRTRPCGRNLYLLWQQHHTDLAQRLNNLNFMVLQSRQQSLLLLCYDHVHPGIRTLLHKYKDDADCEGMLLELRSRIGHEIGL--FIGYPAKDVAAFPFTCQRLWK---YGNPARSLALAEQYRCCRNKMGAILARGTSKTLE......................................................................................................................................... 237
10 -2.330PB048276 _Gut.Meta.Jp.0112258_ gi|163310311|dbj|BABD01000385.1||2 (- 258:885~0 complete)  ali follow..  8  2..............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................NTQIKLSETVMVIDVAYLNDLRKYFEPLLGRSLQTVDLADNDVQVLL-----VYDKQSGKLEHCLPSDLKNELDGVAFKASLGEFSFMAAPSEGFVSRG-------------DLYLDLLQIVLNAAEVKKLIVVP-KEVEN---VLRECALENAGHKEEAKDIVYFRMEEPAAPAVCRWEMLG.............................................................................................................................................. 187
FFAS is supported by the NIH grant R01-GM087218-01
1 4 8 2 6 8   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Friedberg I, Godzik A. Fragnostic: walking through protein structure space. Nucleic Acids Res. 2005 Jul 1;33(Web Server issue):W249-51.