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Query: [E] COG0345 Pyrroline-5-carboxylate reductase, from COG1018

Results of FFAS03 search in NEW_HUMAN_DOMAINS
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MENQKIGFIGAGKMGSALMQGTIKAGIVTPENIGASDVYEPFLKDLQAKLGIRVSTDNAVIVRESDILILAVKPQTLSSVLSNLKNEITSEKLVISIAAGVPLSTYEDALLEGTRVVRVMPNIAATVSEAASGIAPGKNATPEDLKAALEIFSAVGTAVQVPESLMDAVTGLSGSGPAFIFPVIEAMADGAVLEGMDRKSALTLAAQTVLGAAKMALETGMHPGELKDMVTSPAGTTIQGIHSLEEAGIRAAFMNAVIRASERSKELGKKLast
1 -6.430sp|Q13790|APOF_HUMAN Apolipoprotein F OS=Homo sapiens GN=APOF PE=1 SV=2  ali   14  3..................................................................................................................NVVQLLPGVGTFYNLGTALYYATQNCLGKARERGRDGAIDLG---------YDLLMTMAGMSGGPMGLAISAALKPALRSGVQQ........................................................................ 77
2 -4.340sp|Q68DK2|ZFY26_HUMAN Zinc finger FYVE domain-containing protein 26 OS=Homo sapiens GN=ZFYVE26 PE=1 SV=3  ali   8  1...................................................................................................................................................................EAVSVLWDLLRQSPQPAQALLELLLEEDDGTGLCHWPLQNALVDLIRKALRALQGPDSVPPGVVDAIYG---RTLRCPAEPLGVELHLLCEELLEACRTEGSPLREE 106
3 -4.160sp|Q5TG08|YV009_HUMAN Putative uncharacterized protein LOC388900 OS=Homo sapiens PE=1 SV=2  ali   10  9...........................................................................................................................................................................IYGKSPVYFLQNYASLQQHGKNVLIVRREKTTSTPDCTPTYTDVISETLCSMKKRKDNLNQLYQHHWTEWNYFDK........................ 85
4 -3.970sp|Q9NU22|MDN1_HUMAN Midasin OS=Homo sapiens GN=MDN1 PE=1 SV=2  ali   14  1.....................................................................................................................RAMRNRGLEI-----YISGEGDASTPDNLDLKVLLHSLGLVNSVCDILLALHTETRSTVVGSPTSSVSTLIQTALQRGLSLDRAFSEACWEVYVCSQHSPANRKLVQALLEKHVS...................................... 117
5 -3.950sp|Q6UXB0|F131A_HUMAN Protein FAM131A OS=Homo sapiens GN=FAM131A PE=2 SV=1  ali   9  46.......................................................................................................................................................................................FTRLLHPPLSPGISQVVKDHVTKPTAMAQGRVA...................................................... 78
6 -3.870sp|P42356|PI4KA_HUMAN Phosphatidylinositol 4-kinase alpha OS=Homo sapiens GN=PI4KA PE=1 SV=3  ali   15  19............................................................................................................................AVIALGIFLIESDLQHKDCVVPYLLRLLKGLPKVYWVEESTARKGRGALPVAESFSFCLVTLLSDVAYRDPSLRDEILEVLLQVLHVLLGMCQALEIQDKEYLCKYAIP..................................... 127
7 -3.730sp|Q53QW1|CB057_HUMAN Uncharacterized protein C2orf57 OS=Homo sapiens GN=C2orf57 PE=2 SV=1  ali   19  7.................................................................................................................................................................ENSYMRSMTSLLDRGEGSISSLADILVWSETTMGMA--IATGFLDSGHSTVADLLHSSG.................................................. 63
8 -3.680sp|Q9Y238|DLEC1_HUMAN Deleted in lung and esophageal cancer protein 1 OS=Homo sapiens GN=DLEC1 PE=2 SV=2  ali   9  1............................................................................................................................................TQDISHLLTGVFRNLYSAEVIGDEVSASLIKARGSENERHEEFVDQLQQIRELYKQRLDEFEMLERHITQAQARAIAENERVMSQAG---------VQDLESLVRLPPVKSVSRWCIDSELLRKHHL... 118
9 -3.670sp|Q14571|ITPR2_HUMAN Inositol 1,4,5-trisphosphate receptor type 2 OS=Homo sapiens GN=ITPR2 PE=1 SV=2  ali   19  2................................................................................................................................................................LGKYRMDLVLQLKNNASKLLLAIMESRHDSENAERILFNMRPRELVDVMKNAYNQGLECDHGDDEGGDDGVSP..................................... 74
10 -3.590sp|Q5VX52|SPAT1_HUMAN Spermatogenesis-associated protein 1 OS=Homo sapiens GN=SPATA1 PE=2 SV=3  ali   13  1...................................................MSLNPSRPSSSELVELHVFYVPEGSWNYKLNTISTEVVNK----FISAG---------------FLRVSPQLTLRALRERLGEFLGEDAIAEKFLFLKCIGNNLAVVKEKQESELKLKSFAPPYALQPELYLLPVMDHLGNVYSPS......................................................................... 127
FFAS is supported by the NIH grant R01-GM087218-01
1 4 8 3 3 7   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Plewczynski D, Tkacz A, Wyrwicz LS, Godzik A, Kloczkowski A, Rychlewski L. Support-vector-machine classification of linear functional motifs in proteins. J Mol Model 2006 Aug;12(4):453-61. Epub 2005 Dec 10.