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Query: [S] COG4625 Uncharacterized protein with a C-terminal OMP (outer membrane protein) domain, from COG1018

Results of FFAS03 search in NEW_HUMAN_DOMAINS
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MIRGIARRPRCAVEGDWMSAGFCHVSEGKACPTAEMRGVALGRFLICGATGLSFLTLSLAAVSDAVAETLLWTGPDGAEWFTDAAWGPSHRVPNAGDDAMINTYGPVITIGTNAEVHQLSIGNAPGDGTLVVQGGLQTNSVILGATGGSSGTASFIGANWANDGDVSVGGNGTGSLLLLHGTTASSENIYVGESGTGSGSLKLDNSSTLTVADTVFAGYNSWSSSAAGGSGNVEVLGASSLYSANGVLANDPDTVGTALVSGGGSSWNMSSDLVVGEAGVGTLTITGGGMVISQTTTVIADLNSADGSSVTVSRLGSSLQSDSLVVGNGGAAKLVVEAAATVTSGEAIIGRHSASEATVTGDGSKWTTGDLQVGGDTSDPGGLAGNGTLNVTAGGSVDSTVAHLGVVAGATGSAIVDGKGSVWTVDRNSLEVGVSGAGSLAVTGGGLVDAANIIIGTNTGGNGSVRVSGADSTVKSRSDLNVGLYGNGSMTVEAGGAVKSRDGYVATYGGSTSAVTVTGDGSSWAMTGTFFVGYASGATGNVTVSNGGAIRATGVTLGDLAGASGTMTITGAGSKVTAYVDNGTVNSGSVDVGFQGSGSLSVVNGGSLDAYNLYVGNALGSSGAVLVSGVGSHVSVDGLMVVGNAGNGSVEITGGASLAAPTILIATEAGSTGVLSIGAGSGQTARSAGAVEARAIAFGAGNGSIVFNHSETGYTLSADISGAGRVVAEAGVTTLSGNNSYSGGTTISAGMLKGTAKSFGSGGIVNNAELVVDGGGTLSNAISGTGSFEKTGDGNLLLTGNSTYSGATAVSAGKLSVNGSLASAVSVGSGATVGGTGTIGGLTVNSGGTLAPGNSIGTLTSTGNATFASGSTYAVEIDADGSSDRLAVTGTITIANDVSLIVTPLGAHSAYSLGTRYTILTATGGVTGTFSSVDESFAYLTAKVAQSGDDATTYLSFLRTSPDSGLLAAATSTANARAAANAVEALGQTSPLYEAALFLQQGETQGAFSQLAGEIHPSLAMALINRSGQSRDVILNRLRSAFEGVDARPILPVAYAEGGQNPFAVDDGALSFWSSGFRSRGRIDSDGNGSSVDMNGGGILFGLDGELSDSWRAGVAAGYGHDGIKQTALAASADVDSYYLAAYAGTQIGPASLRLGAIHAFQDAETRRSISFSTLQESLSASYGGSTSQVFAEAAWRFDFDLTHIEPYANIAYVNTRTDGFQEKGAIAAVSSGSTRYDQLYTTFGARISRDIALEGMLGRAMFDLAWRHNYGDTAMGSSLFYEGGGVFSVASTSSPRDAAILNLGLSYDLTPSATLTFRYGAVFGAGVLDQSAAAELGVRFLast
1 -3.970sp|Q6UB99|ANR11_HUMAN Ankyrin repeat domain-containing protein 11 OS=Homo sapiens GN=ANKRD11 PE=1 SV=3  ali   13  23..........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................LLDGKPLSKLHIPVIAPPPSLAEPLKELFRQQEAVRGKLRL------HSIEREK----------LIVSCEQEILRVHCRAARTIA----QAVPFSACTMLLDSEDRFNARQFISWLQDVDDKYDRMKTCLLMRQQHE----AAALNAVQRMEWQLKVQELDPAGHKSLCVNESFYVPMVDVNDDFVLLPA..................................... 209
2 -3.800sp|Q92665|RT31_HUMAN 28S ribosomal protein S31, mitochondrial OS=Homo sapiens GN=MRPS31 PE=1 SV=3  ali   10  3...................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................LNIFDMMAVTKEAPETDTSPSLWDVEFAKQLATNGFEELIQWTKEGKLWE------FPINNEAGFDDEFHEHIFLEKHLESFPKQGPIRHF--------MELVTCGLSKNPYLSVKQK----VEHIEWFRNY----------------FN------EKKDILKESNIQFN................................ 142
3 -3.770sp|Q8WVR3|CG043_HUMAN Uncharacterized protein C7orf43 OS=Homo sapiens GN=C7orf43 PE=1 SV=2  ali   9  3...............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................VEEPIVSTDEVIFPLTVSLDRLPPGTPKAK---------------VVTVWKREIEAPEVRDQGSPGETFRGEQSAFKAQVSTLLT-RCRQFTVAGKHLTVLKVLNSSSQEEISIWDIRILPNFNASYLPVMPDGSVL--------------LVDNVCHQSGEVSMGSFCRLPGTSGCFPCPLNALEEHNFL------FQ-------LRGGEQPPPGAKEGL-------------EVPLIAVVQWS------TPKLPFTQSIYTHYRLPSVRLDRPCFVMTASCKSPVRTYERFTVTYT--LLNNLQD--LAVRLVWT. 270
4 -3.690sp|Q2PPJ7|RGPA2_HUMAN Ral GTPase-activating protein subunit alpha-2 OS=Homo sapiens GN=RALGAPA2 PE=1 SV=2  ali   11  1......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................FFLQILLKYMVIQAASLEWKN-KENQDTGFKFLFTLFRKYY---LPHLFPS----FTKLTNIYKPVLDIPHLRPKPVYITTTRDNENIYSTKIPYMAARVVF--------------------IKWIVTF...................................................................... 101
5 -3.630sp|Q6GYQ0|RGPA1_HUMAN Ral GTPase-activating protein subunit alpha-1 OS=Homo sapiens GN=RALGAPA1 PE=1 SV=1  ali   11  1......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................YFLEALLKYIVIQVKSLEWKN-KENQERGFSFLFSHFKKYY---LPYIFPN----ICKENSLYHPILDIPQMRPKPH-------YVVIKKDAETNEAIYCTKEPFIKARVIV----------IRWLVSF...................................................................... 104
6 -3.480sp|Q96QE3|ATAD5_HUMAN ATPase family AAA domain-containing protein 5 OS=Homo sapiens GN=ATAD5 PE=1 SV=4  ali   10  1.............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................AKRDFLMSGLPDLLKRQIAKKAAAL--------DVYNAVSTSFQRVVHVQQKDDGCC----FKELNTKVIDLSKCGIALG-EFSTLNSKLKSGNSAAVFMRTRKEFTEEVRNLLLE-WSNPEF-----SLKK----------------------FP-LLLKKQIEH.......... 142
7 -3.460sp|Q15345|LRC41_HUMAN Leucine-rich repeat-containing protein 41 OS=Homo sapiens GN=LRRC41 PE=1 SV=3  ali   9  2..................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ALFELCGRAVSAHMGVLESGV-WALPGPILQS--ILPLLNIYYLERI-----------------EETALKKGLSTQAIWRRLW-LMKTRPSSLESV------------------TCWR------FMEAFFSHVLRGTIDVSSDRRL-LHSSRHVRQLTICNMLQGATELVAEPNRRVLETLASSLHT-----------KFRHLLFSDVAAQQSLRQLLHQLIHHGAVSQ----VSLYSWPVPESALFILI-LTMSAGF--------------WQ......................................................................... 212
8 -3.270sp|A6NDU8|CE051_HUMAN UPF0600 protein C5orf51 OS=Homo sapiens GN=C5orf51 PE=1 SV=1  ali   9  4............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................SNLLELYTQAILDMTY-FEENKLVDEDFPEDSSSQKVKELISFLSEPEILVKENNMHPKHCNLLGDELLE--------------LSWRHSLTKRREWLLRKSSLLKKYLLDGIPIQLNAKLLSAGI---FSDIHLLAMMYSGEM................. 160
9 -3.260sp|A6NJV1|CB070_HUMAN UPF0573 protein C2orf70 OS=Homo sapiens GN=C2orf70 PE=2 SV=1  ali   6  12.....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................SYTRFNLDSHRSTELTNFYQ---------MVQQHRK--YQDKTG--TVPRVPYFAMPVREPERYPLPTVLPPLCPKKKWHLLRLAPENLKTYQTFPSGKRVSPQERKK--RDCY----------------FEFRA................................................. 116
10 -3.260sp|Q8WV92|MITD1_HUMAN MIT domain-containing protein 1 OS=Homo sapiens GN=MITD1 PE=1 SV=1  ali   12  1.....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................LFREY---LNETVTEVDPYIRHTHQLYNFLRFCE----MLIKRPCKVKTIHLLTSLDEGIEQVQQSRGLQEIEESLRLEVQYSSSIHDREIRFNNG-------------MIKIGRGLDYFKKPQSRFSLGYCDFDLRPCHETTVD....... 134
FFAS is supported by the NIH grant R01-GM087218-01
1 4 7 8 6 2   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Jaroszewski L, Rychlewski L, Zhang B, Godzik A. Fold prediction by a hierarchy of sequence, threading, and modeling methods. Protein Sci. 1998 Jun;7(6):1431-40.