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Query: [S] KOG1008 Uncharacterized conserved protein, contains WD40 repeats, from COG1018

Results of FFAS03 search in NEW_HUMAN_DOMAINS
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MSGNTHGLSWFPHFPDKFVSWGQEIHLYEVRRKDDHSQKSRLPYISVNYLANESRYQYARCVAASYHSDQPIIAVGLADGKVGICNFRDTYDSSWEYTPRQQRMCTCLAWNELDANILAIGHDRHRNDTCITIWDIERGVPKETANFFGVGESANSICWDRNHRTVIAGMSQKMIKLFDLRQSNATCQSIQTKTVQGLSVSPNGNYLCSYVDSVITLWDPRNIKSPLRQIQSSKNHLQIAWCPTRTSLLSSLQRDSSYITLYDIRSVDTDNSGEIYHVKRQISPFPARYQHSGKFSFVNCLSWHSRDFERALLLADALNILDFRLPATLHTAHSNRRKLPLLMQRPLYTPASPTSTAATPTQQQPTSSCSTNSGSSLDFSTPGGSPFNVDLLKPELFELDLVDETRQRALEDYGIKPDNKRFGELHLTPYLRNVWSTLNNVYSEDRLTGLKATLGINLGHTSEALMASSRIESQVLQWPEGINNSNKLICYRSEQRDLALQLCGWAFEQELDRFIDQLYANKEYSRAAMICVFHLKIFHACNILSSAADNMRDPSMYRITVIALSSFNADRCSSTWRNQRSSANMQIHDPHLRAVFSFLTMEKDNFDAVLKEEGVSLSDRMAFACKYLSETKLADYVAQQIQAAIDGGDLNGLLLTGESQDGIDILQSYMDTSFDVQTVALVAINYFRQELFEDKRIQYWIASYLDHLNSWGLWEKRAELDIKIESIRPSSRSSRTVFLSCNFCGKSVSNALLDEPRPRSTTTSTNRLSSCPSCRKPLPRCSLCLLast
1 -12.300sp|Q9UKN8|TF3C4_HUMAN General transcription factor 3C polypeptide 4 OS=Homo sapiens GN=GTF3C4 PE=1 SV=2  ali   10  20..................................................TIESGITSPSVLFWHNNRKMSGLIVGSAFGPIKILPVNLKAVKGYFTLEMDQLPVHSIKCQKCSCSLVVAA----RGSYVFWCLSKAGLNVHNSHVTGLHSLPIVSMTADKQNGTVYTCSSDGKVRQLIPIFTDVALKFEHQLRTHGIAVSPCGAYLAIITTEG-MINGLHPVNKNYQ-------VQFVTLKTFEEAAAQLLESSVQNLFQVDL......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 254
2 -11.800sp|Q96S15|WDR24_HUMAN WD repeat-containing protein 24 OS=Homo sapiens GN=WDR24 PE=1 SV=1  ali   28  22.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................DMLHFYAE-QGDVQMAVSVLIVLGERKDIDEQTQEHWYTSYIDLLQRFRLWNVSNEV................................................................. 79
3 -7.780sp|Q5T197|DCST1_HUMAN DC-STAMP domain-containing protein 1 OS=Homo sapiens GN=DCST1 PE=2 SV=1  ali   16  2.................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................DLLKKRAAFTKLRRAAILRRERQQKAPRHPLADIRCVVCQAP------ETPESYVCRTLDCEAVYCWSCWDDMRQCPVC. 89
4 -6.960sp|Q7Z2Y8|GVIN1_HUMAN Interferon-induced very large GTPase 1 OS=Homo sapiens GN=GVINP1 PE=2 SV=2  ali   9  6........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................MTLTVFEKEFINMTTDYIVSRFNKIINNMWKQQCGYNPNYFHEILK-TIEEEVKSASTQKRYTFTNTFIIDLCVCLFQRARENFKEMHRAFKRAYLESKKDDFFTSFKISCQGATSI-TTIWEDMTFKIAGDMHILFSLAEEENFDNYWEYLHNKSFFRSYIKNHIKRYCSDNGGEKMKTFFEKSLIKNTILSAIHESTSVAKDKSSTASEWLDLFCDCLGCNLIFPRRDLISIEHQEIKHTEFLKEAMSAALDLTMKKIEQNYSSKPIEAMVSKIEKMLEHLCGCWKQCPSCAIC. 341
5 -6.310sp|Q9UBI9|HDC_HUMAN Headcase protein homolog OS=Homo sapiens GN=HECA PE=1 SV=1  ali   11  9.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................GPRSSRYLGEFLKNAIHLEPHKKAMAGGHVFRNAHFDYSPAGLAVHRGGRRLDLSELLTHIPRHKLNTFHVRMEDDAQV---QGEDLRKFILAALSASHRNVVNCALCHRALPVFEQFPL--------------------------VDGTLFLS-DEIEYDVPCHLQGRLMHLYAVCVIICIKCKSRWDGSWHQLGTMYTY-DILAASPCCQAR---------------------LNCKHCGKPV----IDVRIGMQYFSEYSNVQQCPHCGKPFSSFKV.. 261
6 -6.240sp|Q8IYV9|IZUM1_HUMAN Izumo sperm-egg fusion protein 1 OS=Homo sapiens GN=IZUMO1 PE=1 SV=2  ali   12  5.....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................DPSVVLALKSLEKDYLPGH----------AKHHKAMMERVENAVKDFQELSLNE------------------DAYMGVVDEATLQKGSWSLLKDLKRITDSDVKGDLFVKELETFATYVARFQKEAYCPNKCGVMLQTLIWCKNCKKEVHACR-C. 144
7 -6.220sp|O43593|HAIR_HUMAN Protein hairless OS=Homo sapiens GN=HR PE=1 SV=5  ali   16  7........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................LSGLGDRLCRLLRR----REALAWAQREGQGPAVTEDSPGIPRCCSRCHHGLFNTH-----------------RCPRCSHRL--CVAC. 73
8 -5.980sp|Q9UG01|IF172_HUMAN Intraflagellar transport protein 172 homolog OS=Homo sapiens GN=IFT172 PE=1 SV=2  ali   9  4................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ATRSAAQSVKQLETVAARLS---SLLRHTQLLPVDKAFYEAGIAAKAVGWDNMAFIFLNRFLDLTDAIEEGTLDGLDHSDPFEVPLPAKQHVPEAEREEVRDWVL--TVSMDQRLEQVLPRDERGAYEASLVAASTGVRALPCLIT------GYPILRNKIEFKRPGKATSHSPVC. 189
9 -5.900sp|Q5VZ72|IZUM3_HUMAN Izumo sperm-egg fusion protein 3 OS=Homo sapiens GN=IZUMO3 PE=2 SV=4  ali   9  2...............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................LECDPKFIEDVGSLLGNLIPSE---VPGRTQLLERQIKEMIHLSFKVSHSDKRL--RVLAVQQVVKLRTWLKNEFYKLGNE--TWKGVFIYQGKLLDVCQNLESKLKELLKNFSEIA--------------------------------CEDCI-----------------VVEGPILDCWTCLRMTNRCEYC. 142
10 -5.570sp|Q5TYM5|FA72A_HUMAN Protein FAM72A OS=Homo sapiens GN=FAM72A PE=2 SV=1  ali   22  1...................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................MSTNICSFKDRCVSILCCKFCKQVLSSRGMKAVLLADTEIDKLKDIACLKCGNIVP-CSSCL 93
FFAS is supported by the NIH grant R01-GM087218-01
1 4 7 5 5 3   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Veeramalai M, Ye Y, Godzik A. TOPS++FATCAT: fast flexible structural alignment using constraints derived from TOPS+ Strings Model. BMC Bioinformatics. 2008 Aug 31;9(1):35