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Query: [T] KOG2289 Rhomboid family proteins, from COG1018

Results of FFAS03 search in NEW_HUMAN_DOMAINS
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MANRDVERVGKKNRGANNNYFYEESSGETHWTSWLIPAIVVANLAVFIAVMFVNDCPKKITGPNKECVARFLGRFSFQPLKENPLFGPSSSTLEKMGALEWRKVVHEHQGWRLLSCMWLHAGIIHLLTNMLSLIFIGIRLEQQFGFIRVGLIYLISGLGGSILSSLFLQESISVGASGALFGLLGAMLSELLTNWTIYANKAAALITLLFIIAINLALGMLPRVDNFAHIGGFLTGFCLGFVLLVRPQYGWEASRTNTSRTKRKYSMYQYVLFVVSVVLLVVGLTVALVMLFKGENGNKHCKWCHYLSCFPTSKWTCLast
1 -11.200sp|Q96CC6|RHDF1_HUMAN Inactive rhomboid protein 1 OS=Homo sapiens GN=RHBDF1 PE=1 SV=2  ali   13  174.KRQFGSVCHQDPRVCDEPSSEDPHEWPEDITKWPICTKNSTNHPHMDCVITGRPCCIGTKG-RCEITSREYCDFMRGYFHEEATLCSQVHCMDDVCGL.......................................................................................................................................................................................................................... 274
2 -5.910tr|E9PGJ1|E9PGJ1_HUMAN Uncharacterized protein OS=Homo sapiens GN=RHBDF1 PE=4 SV=1  ali   15  1..............................................MDCVITGRPCCIGTKG-RCEITSREYCDFMRGYFHEEATLCSQVHCMDDVCGL.......................................................................................................................................................................................................................... 52
3 -4.600sp|Q6PJF5|RHDF2_HUMAN Inactive rhomboid protein 2 OS=Homo sapiens GN=RHBDF2 PE=1 SV=2  ali   13  187.KRTSGAVCHQDPRTCEEPASSGAHIWPDDITKWPICTEQATGFLHMDCEIKGRPCCIGTKG-SCEITTREYCEFMHGYFHEEATLCSQVHCLDKVCGL.......................................................................................................................................................................................................................... 287
4 -4.480sp|Q92542|NICA_HUMAN Nicastrin OS=Homo sapiens GN=NCSTN PE=1 SV=2  ali   9  7.......................................................................................................................................................IYI--PLNKTAPCVRLLNATHQIGCQSSISGDTGVIHV--VEKEEDLQWVLTDGPNPPYMVLLESKHFTRDLMEKLKGRTSRIAGLAV.............................................................................. 90
5 -4.460tr|Q5T211|Q5T211_HUMAN Nicastrin (Fragment) OS=Homo sapiens GN=NCSTN PE=2 SV=1  ali   9  7.......................................................................................................................................................IYI--PLNKTAPCVRLLNATHQIGCQSSISGDTGVIHVVEKEEDLQWVLTDGPNPPYMVLLESKHFTRQNVRLSDTFLCSFMEF.................................................................................. 88
6 -4.380sp|O94923|GLCE_HUMAN D-glucuronyl C5-epimerase OS=Homo sapiens GN=GLCE PE=1 SV=3  ali   14  193..........................................................................................................................IISFDLKFLTNGSVSVVLETTEKNQLFTIHYVSNAQLIAFKERDIY---YGIGPRTSWSTVTRDLVTDLRKGVGLSNTKAVKPTKIMPKKVVRLIAKGKGFLDNIAHMAAFF................................................................................... 306
7 -4.330sp|O43593|HAIR_HUMAN Protein hairless OS=Homo sapiens GN=HR PE=1 SV=5  ali   8  1....................................................................................................................................................................................................................................GLAKHLLSGLGDRLCRLLRREREALAWAQREGQGPAVTEDSPGIPRCCSRCHHGLF-----------NTHWRCPRCSHRLCVA-----C 73
8 -4.300tr|Q5T210|Q5T210_HUMAN Nicastrin (Fragment) OS=Homo sapiens GN=NCSTN PE=2 SV=1  ali   9  16.......................................................................................................................................................IYI--PLNKTAPCVRLLNATHQIGCQSSISGDTGVIHV--VEKEEDLQWVLTDGPNPPYMVLLESKHFTRDLMEKLKGRTSRIAGLAV.............................................................................. 99
9 -4.280sp|Q8N6T0|CK080_HUMAN Putative uncharacterized protein C11orf80 OS=Homo sapiens GN=C11orf80 PE=2 SV=1  ali   13  69................................................................................................................LVIKHFLRIIMVHPKVRFHFSVKVGILSTEIFGVENEPTLNLGNGVLGHPVMLFIPEDVAGMDLLGELILTPAAALCPSPKVSSNQLNRISSVSIFLY-LPLILSTWEQPMTTFFKDTSSLVDWKKYHLCMIPNLDLN................................................................... 238
10 -4.200sp|Q6UY27|PATE2_HUMAN Prostate and testis expressed protein 2 OS=Homo sapiens GN=PATE2 PE=2 SV=1  ali   33  12...........................................................................................................................................................................................................................................................................................................MCYECKKYSCSLKHKQSC 39
FFAS is supported by the NIH grant R01-GM087218-01
1 4 8 3 4 1   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Jaroszewski L, Slabinski L, Wooley J, Deacon AM, Lesley SA, Wilson IA, Godzik A. Genome pool strategy for structural coverage of protein families. Structure. 2008 Nov 12;16(11):1659-67.