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Query: [S] KOG2632 Rhomboid family proteins, from COG1018

Results of FFAS03 search in NEW_HUMAN_DOMAINS
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MRPNIVTEAGVQTRVGQWWNAIPFLTSSVVVVCGVIYLICLLTGYDTFYEVCFLPSAIISRFQVYRFYTAIIFHGSLLHVLFNMMALVPMGSELERIMGSVRLLYLTVLLATTNAVLHLLIASLAGYNPFYQYDHLMNECAIGFSGILFSMIVIETSLSGVTSRSVFGLFNVPAKLYPWILLIVFQLLMTNVSLLGHLCGILSGFSYSYGLFNFLMPGSSFFTTIESASWMLIVTHPVSMSSSSLASLGDPSSLCVLAGILPAIFPLILHKTQHPGNAWRSLSSWLPQREASNQSSEDSRFPGRGRTLSTARDPTAPAGETDPNLHARLLEDSSSPDRLSDATVNTVADSRQAPIANAAVLPQSQGRVAASEEQIQKLVAMGFDRTQVEVALAAADDDLTVAVEILMSQQVLast
1 -8.390sp|Q13470|TNK1_HUMAN Non-receptor tyrosine-protein kinase TNK1 OS=Homo sapiens GN=TNK1 PE=1 SV=3  ali   17  20................................................................................................................................................................................................................................................................................................................................................................................AIRNLKVDQLFHLSSSRADCWRILEHYQWDLSAASRYVLAR.. 61
2 -7.430sp|Q9BX84|TRPM6_HUMAN Transient receptor potential cation channel subfamily M member 6 OS=Homo sapiens GN=TRPM6 PE=1 SV=2  ali   9  15........................................................................................................................................................................................................................................................................................KRVPFSAETVLPLSRPSVPDVLATEQDIQTEVLVHLTGQTPVVSDWASVDEPKEKHEPIAHLLDGQDKAEQVLPTLSCTPEPMTMSSPLSQAKIMQTYVNWAF-----------SEGDETGVFSIKKKWQT 137
3 -6.590sp|O75113|N4BP1_HUMAN NEDD4-binding protein 1 OS=Homo sapiens GN=N4BP1 PE=1 SV=4  ali   12  3........................................................................................................................................................................................................................................................................................................................................................AGNVIADLSDSSADSENLSPDIKETTEEMEYNILVNMGYSQEIVEKVIKVYG--PSTEPLLLLEE.. 69
4 -5.380sp|P56715|RP1_HUMAN Oxygen-regulated protein 1 OS=Homo sapiens GN=RP1 PE=1 SV=1  ali   6  13...............................................................................................................................................................................................................................................................................................SPCEMCTVNKAYSPKETCNPSDTFFPSDGYGVDQTSMNKACFLGEVCSLTDTVFSDKACAQKENHTYEGACPIDETYVPVNVCNTIDFLNSKENTYTDNLDSTEELERGDDIQKDLNILT.... 132
5 -5.210sp|Q6PJF5|RHDF2_HUMAN Inactive rhomboid protein 2 OS=Homo sapiens GN=RHBDF2 PE=1 SV=2  ali   10  23LNRSYRRSISSTVQLESFDSHRPYFTYWLTFVHVIITLLVICTYG--IAPVGFAQHVTTQLVLRNKGVYESVKYIQQENFWVSSIDLIHLGAKFSPCI......................................................................................................................................................................................................................................................................................................................... 122
6 -5.130sp|Q711Q0|CJ071_HUMAN Uncharacterized protein C10orf71 OS=Homo sapiens GN=C10orf71 PE=2 SV=2  ali   12  1..........................................................................................................................................................................................................................................................................................................................................................MMQGNKKCTDAFSDSSSIGSVLDDADREVSSLTDRAFR------SLCISEHDSYLAVSPDITRQV 63
7 -4.850tr|F8W6C2|F8W6C2_HUMAN Uncharacterized protein OS=Homo sapiens GN=SPATS2L PE=4 SV=1  ali   12  2..........................................................................................................................................................................................................................................................................................................................................................................AELNTHVNVKEKIYAVRSVNKSNNEIVLVLQQFDFNVDKAVQAFVDGSA 52
8 -4.850sp|Q9NUQ6|SPS2L_HUMAN SPATS2-like protein OS=Homo sapiens GN=SPATS2L PE=1 SV=2  ali   12  2..........................................................................................................................................................................................................................................................................................................................................................................AELNTHVNVKEKIYAVRSVNKSNNEIVLVLQQFDFNVDKAVQAFVDGSA 52
9 -4.740sp|A0AUZ9|CB067_HUMAN Uncharacterized protein C2orf67 OS=Homo sapiens GN=C2orf67 PE=1 SV=2  ali   8  1........................................................................................................................................................................................................................................................................................................TSQCMKDVQIILDSNITKDTNVDKVQLQNCKWYQENALLDKVTDAEIKKGLLHCTQKKIVPGHSNVPVSSSAAEKEEEVHARLLHCVSKQK---ILLSQARRTQKHLQMLLAKHV 112
10 -4.600sp|Q9H799|CE042_HUMAN Uncharacterized protein C5orf42 OS=Homo sapiens GN=C5orf42 PE=2 SV=3  ali   8  13...........................................................................................................................................................................................................................................................................................DQYVGQENLTPQQDSSVFIKPEKLFDVKPGTLEISPHHSFGLPLLYLPLKPPNMFPSTSRASITVPSTPIQPIAEERKYPRLSLLHSHLSKKTQLIPLAFKQSQQKLTHNLFEQGDAGHLQLLKVK.. 147
FFAS is supported by the NIH grant R01-GM087218-01
1 4 8 3 3 7   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Plewczynski D, Tkacz A, Wyrwicz LS, Godzik A, Kloczkowski A, Rychlewski L. Support-vector-machine classification of linear functional motifs in proteins. J Mol Model 2006 Aug;12(4):453-61. Epub 2005 Dec 10.