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Query: [DL] KOG2810 Checkpoint 9-1-1 complex, RAD9 component, from COG1018

Results of FFAS03 search in NEW_HUMAN_DOMAINS
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MKYTLEGSNARVIAKAVQSLSKVGKEMFIEIDQQSLQMRAINATQSAVGSISFKRSMFEVYDMPPHSDFYCKISMKGCLAVFRNMNEVEYCELNLLDNQTNLQVNLRCKLETTKEATISIIDDQNINTNINTDQMPNIIRGDHKLLTDISNNFNSSEEELTLEANSGSVVAKNYIEGARVNDKFMRTQLKLKPSEFEQYQVTKETVITFCIKEFRAFLLFAECLNASLTLEFDEAGMPFLLKIKKHGEIECLLIMSTLSPDDISFSEDYCQKDLTVQDEDVRAAAAKRKSSVSKPNVTNKRKGSSSEPAAVQPKRRVEETQLESSLDNPLFQFRDSEAPSVQHPRILAEVDTVVLIEDEAEQEALMLAAADAALEASMAPAPEPPNSTEVCFINTDDSQQPKPAKSSSDEDETIPQSPERPNKVLGVLLGLLQGCVSRLKTMLRLDEHLISGYELLLast
1 -6.890sp|Q8N7X0|CAN7L_HUMAN Calpain-7-like protein OS=Homo sapiens GN=C6orf103 PE=2 SV=3  ali   7  1LLMKARIPDTKENISVADTLQKVWAVLEMNLEQYAVSLLMFKSKCKSLESYPCYQDEETKIAFADYTVTYQEQPPNSWFIVFRETFLVHQLVPKVYTTLPICILHIVNND---TMEQVPKVFQKVVPYLYTKNKKGYTFVAEAFTGDTYVAASR-------------KLRLIGSSAPLPCLSRDSPCN-SFAIKEIRDYYIPNDKKILF-----RYSVKVLTPQPATIQVRTSKPDAFIKLQVLENE................................................................................................................................................................................................................. 231
2 -5.710tr|F5GZE9|F5GZE9_HUMAN Uncharacterized protein OS=Homo sapiens GN=TMEM146 PE=4 SV=1  ali   8  8................LEILTPLRDTAFPAFDFQKCLVNIQALLMDPELHVFLTGEFIYRYTIDMHSQLELTASL---LIPLVMVSNPHSLGFQATFYENGYTSDTKYKLDIFLKQQQHWGRTDSNFTSSLKKATMSTLTVDIANKEISCVDIKPLSTLISVGCDLDKIVIQNKVSALDPLTLQDNYSFIIEKEFYDP-QSSEDLHVFYSYQQL----------GCPLLVYYDTLWKPVVELLESSGMNTVHCSL......................................................................................................................................................................................................... 259
3 -5.480sp|Q5T1R4|ZEP3_HUMAN Transcription factor HIVEP3 OS=Homo sapiens GN=HIVEP3 PE=1 SV=1  ali   8  1..............................................................................................................................................................................................................................................................LGPTVPYTEALQVFHHPVAQTPLHEKPYLPPPVSLFSFQHLVQHEPGQSPEFFSTQAMSSLLSSPYSMPPLPPSLFQAPPLPLQPTVLHPGQLHLPQLMPHPANIPFRQPPSFLPMPYPTSSALSSGFFLPLQSQFALQLPGDVESHLPQ.................................................... 150
4 -5.230sp|Q6ZTY8|CL063_HUMAN Putative uncharacterized protein C12orf63 OS=Homo sapiens GN=C12orf63 PE=2 SV=2  ali   6  1.........................................................................NLCVMDHFMKIFLYCRRAMVLAHRGGYWTLLQNCCRA-ILLKQAVDLDKTFPISQDGFLCTSVLPFYLGAELLIDMLIQLQNTSSIKPIE-DKGEFSVPSCYGNIKNDNGGSSLTFEHPLDDVNVVDLK-SLEVLYQVEKWETLVSLAIQFNTVSHERYTEQVTPLLVYAQRQ.................................................................................................................................................................................................................. 187
5 -5.070tr|E9PJL5|E9PJL5_HUMAN Uncharacterized protein OS=Homo sapiens GN=C12orf63 PE=4 SV=1  ali   6  1.........................................................................NLCVMDHFMKIFLYCRRAMVLAHRGGYWTLLQNCCRA-ILLKQAVDLDKTFPISQDGFLCTSVLPFYLGAELLIDMLIQLQNTSSIKPIE-DKGEFSVPSCYGNIKNDNGGSSLTFEHPLDDVNVVDLK-SLEVLYQVEKWETLVSLAIQFNTVSHERYTEQVTPLLVYAQRQ.................................................................................................................................................................................................................. 187
6 -4.700tr|E9PJ76|E9PJ76_HUMAN Uncharacterized protein OS=Homo sapiens GN=C1orf94 PE=4 SV=1  ali   9  4.........................................................................................................................................................................................................................................................................................................AEKNLLYEFLGATKNPSGQPRLRNKVEVDGPELKFNAPVTVADKNNPKYTGNVFTPHFPTAMTSATLNQPLWLNLNYPPPPVFTNHSTFLQYQGLYPQQAARMPYQQALHPQLGCYSQQVMPYNPQQMG-----QQIFRSSYTPLLSYIPFVQPNY... 154
7 -4.630sp|Q9NVC6|MED17_HUMAN Mediator of RNA polymerase II transcription subunit 17 OS=Homo sapiens GN=MED17 PE=1 SV=2  ali   12  3...................................AHWSNINDVYESSVKVLITSQGYEQI---KSIQLQLNIGVEQIRVVHR-----DGRVITLSYQEQELQDFLLSQ---MSQHQVHAVQQ............................................................................................................................................................................................................................................................................................................................................. 80
8 -4.580sp|P21359|NF1_HUMAN Neurofibromin OS=Homo sapiens GN=NF1 PE=1 SV=2  ali   9  15LYMFLWNPDTEAVLVAMSCFRHLCEEADIRCGVDEVSVHNLLPNYNTFMEFASVSNMMSTGRAALQ---------KRVMALLRRIEHPTAGNTEA......................................................................................................................................................................................................................................................................................................................................................................... 100
9 -4.580sp|Q3MIX3|ADCK5_HUMAN Uncharacterized aarF domain-containing protein kinase 5 OS=Homo sapiens GN=ADCK5 PE=2 SV=2  ali   14  1............FEAVMAVLRELPRPMLLVLRNINT-VRAINVAGAPVDRYFLMAKRAVRGWSRLAGATYRGVYGTSLLRHAKVVWEMLKFEVAL......................................................................................................................................................................................................................................................................................................................................................................... 83
10 -4.540sp|Q8TDB6|DTX3L_HUMAN E3 ubiquitin-protein ligase DTX3L OS=Homo sapiens GN=DTX3L PE=1 SV=1  ali   7  73...CVSLADSKQANKFKQELNHQFTKLLIKEKGGELTLDDISAAKQKISEAF--VKIPVKLFAANYMMNVIEVDSAHYKLLISEIEKRYDICSKVSEKGQKTCILFESKDRQVDLSVHAYASFIDAFQHASCQLMREVLLLKSLHQTKFADDFRKRHPNVHFVLNQESMTLTG........................................................................................................................................................................................................................................................................................... 258
FFAS is supported by the NIH grant R01-GM087218-01
1 4 7 8 6 9   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Liu T, Rojas A, Ye Y, Godzik A. Homology modeling provides insights into the binding mode of the PAAD/DAPIN/pyrin domain, a fourth member of the CARD/DD/DED domain family. Protein Sci. 2003 Sep;12(9):1872-81.