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Query: [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily, from COG1018

Results of FFAS03 search in PDB1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MIVIKFRGRHRLIRRVSGQVYLWLAIFIFGASSAVTRKLTEIGARHFIDGRNPISLCNVLFVGNLCALMVMLLIYSRQWNKATLTQLSKKDWLGLTAVAILSGALAPGLIFHALSLTGVNNVILVGRLEPTLALALSVWLLKEQINFGEFIGAIAAFIGVILTIILQPPVSDMMNMGGWQLGLGEFFVAAGSVALAISTIIGKKYLTHIPLGIYSIFRTALGTVIFFFIALVLYGREHFADVFSPFLWQWMFLYGGVIVVVGQSFWLIGLKTSTVSTASLVASFTPIAGIVAAYFILSEVPTVAQYLGGGLIMLGIFLSQISKSRQTSHKSPIASTPAEQKVEMDMGFKGMLast
1 -82.1005i20_A mol:protein length:298 Uncharacterized protein  ali model follow..  15  1............MSRSSATLIGFTAILLWSTLALATS---------STGAVPPFLLTALTFTIGGAVGIAAGLA-------RGVGLSVLRQPWPVWVHGIGGLFGYHFFYFSALKLAPPAEAGLVAYLWPLLIVLFSAFLPGERLRPAHVAGALMGLAGTVVLL----GARAGGFGFAPEYVPGYLAAAACAVIWSVYSVASRRFARVPTEVVAGFCLATAALSALCHILF------EPSVWPVGSEWLAVVALGIGPVGIAFYTWDIGMKRGDVRLLGVLSYAAPVLSTLLLVVAGFAAPSGALAIACALIVGGAAVATLLARRLESSGENLYFQ............... 298
2 -37.5005y78_A mol:protein length:329 Putative hexose phosphate translocator  ali model follow..  12  1..MSPQKSSVGVSPTLVHTLKVGFYFFLW----YFFNFIFNIANKRTLNMWKPWVLSTIQLGVGALYCTFLWVL-----GLRTKPNVSKKLIKALIWPSLG-HTLGHAATCMSFSLVAISFTHVVKSAEPVFGAVGSALVLGEFFHPLTYLTLVPIVSGVALSAATELT-------------TGFITAMISNVAFVTRNITSKFTMVDLIAQNTYALITIISFFMELPFALLMEGFPPLVSAIAGVSKAKLFGSIMFCSLFYHLYNEVSLDNVSPVSFSIGNTIKRVIIIFGSILVFRTPVTRLNFIGSTIAIIGTMLYSLAKAKLPSKREKQGTENLY............ 327
3 -33.7005oge_A mol:protein length:337 GDP-mannose transporter 1  ali model follow..  10  1.....MSELKTGHAGHNPWASVANSGPISILSYCGSSILMTVTNKFVVNLKDNFVMLFVQSLVCTITLIILRIL--------KFRSLNKTDAKNWFPISFL-LVLMIYTSSKALQYLAVPIYTIFKNLTIILIAYGEVLFFGGSVTSMELSSFLLMVLSSVVATWGDQQAVAAKAASLAEGAPGYFWMFTNCITSALFVLIMRKRIKNFKDFDTMFYNNVLALPILLLFSFCVEDWSSVNLTFSNDSLTAMIISGVASVGISYCSG-WCVRVTSSTTYSMVGALNKLPIALSGLIFFDAPRNFLSILSIFIGFLSGIIYAVAKQKKQQAQPLRK................. 337
4 -16.7002i68_A mol:protein length:137 Protein emrE  ali model follow..  6  33...........................................................................................................................................................................................................................................................SVGTIICYCASFWLLAQTLAYIPTGIAAIWSGVGIVLISLLSWGFFGQRLDLPAIIGMMLICAGVLIINLLSRSTPHEFEAYVEQKLISEEDLNSA.... 129
5 -7.3905xpd_A mol:protein length:293 sugar transporter  ali model follow..  11  14....................................................................................................................ILGNIISFVLFLAPV--PTFVRICKKKSTEGFQSLPYVSALFNAMLWIYYAMQKDGTAFLLITINAFG---CVIETIYIVLFVSYANKKTRISTLKVLGLLNFLGFAAIVLVCELLTKGSTREKVLGGICVGFSVSMFAAPLSIMRVVVRTRSVEFM-PFSLSLFLTINAVTWLFYGLAIKDFYVALPNVLGAFLGAVQMILYIIFKYYKTPVAQMKK................. 225
6 -6.5303ug9_A mol:protein length:333 Archaeal-type opsin 1, Archaeal-type opsin 2  ali model follow..  6  70.........................................................ILQWITFALSALCLMFYGYQTWKST-----CGWEEIYVATIEMIKFIIEYFHEFDEPAVIYSSNGNKTLLTCPVILIHLSNLTGLANDYNKRTMGLLVS--DIGTIVWGTTAALSKGYVRVIFFLMG--LCYGIYTFFNAAKVYIEAYHTVPKGRCRQVVTGMAWLFFVS-----------------------GMF-------ILFILGPEGFGVLSVYGSTVGHTIIDLMSNCWGLLGHYLRVLIHEHILIHGDIRKTTKLNIGGTEIEVETLVEDEAEAGAVSSEDLYFQ.. 333
7 -6.4306b2z_k mol:protein length:68 ATP synthase subunit k, mitochondrial  ali model follow..  14  1.................................................................................................................................................................................................................................................................................................MGAAYHFMGKAIPPHQLAIGTLGLLGLLVVPNPFKSAKPKTVDIKTDNKDEEKKHSEKQDA. 68
8 -6.4006g1k_A mol:protein length:921 Transient receptor potential cation channel subfamily c member 4a  ali model follow..  9  267LILNFRDDMNLLQDEANNELARLKLAIKYRQKEFVAQLLASRWYDEFPGWRRRHWAGKLITCVFIGLMFPLLSLCYLVAPKSRYGLFIRKPFIKFICHTASYLTFLFLLLLASQNNPDRQGPKPTTVEWMILPWVLGFIYIHDWWNLMDFVMNSLYLATISLKIVAYVKYSGCKPRDTWETLVAEAVFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIY--------------------CLVLLAFANGLNQLYFYYENSEGMTCKGIRCERQNNAFSTLFETLFVGATMFGTYNVISLVVLLNMLIAMMNNSYQHIADHADIE................ 634
9 -6.2005oql_B mol:protein length:907 Utp2  ali model follow..  8  504VQRIRALHHPKLDAKNKERLGNFSQVLI------HIAYLGDRFQPHWFPTLEQLSRHVHSLAKTFPIEVAKAYRMRIQEMEEHRPLPTVGDLVILTAIGTT-CTPAMLAIARYLGQKVPAALSDFAVGIYLSILALQYQDFAKRYVPE----MMNFLLNTLCALAPERAKSKLGNFPVHEPPAGIRIKDATNTPIRQLNCGDCLRKDELSPAETSSLQIAILSTATAILKSAADTWHKLPAFIE--------SFQPALSVAQHLLTKPNASHLPSSLTSKLNDLASHLSRLLQLS---RPLELHHHRPLAIKTYIPKFEDDFDPDKHYDPNRERAELAKLKAEHKRERKGA 848
10 -5.9702jo1_A mol:protein length:72 Phospholemman  ali model follow..  18  22.................................................................................................................................................................................................................................................................................................................VIAGILFILGILIVLSRRCRCKFNQQQRTGEPDEEEGTFRSSIR.. 65
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Plewczynski D, Tkacz A, Wyrwicz LS, Godzik A, Kloczkowski A, Rychlewski L. Support-vector-machine classification of linear functional motifs in proteins. J Mol Model 2006 Aug;12(4):453-61. Epub 2005 Dec 10.