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Query: [R] COG0705 Uncharacterized membrane protein (homolog of Drosophila rhomboid), from COG1018

Results of FFAS03 search in PDB1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MLMITSFANPRVAQAFVDYMATQGVILTIQQHNQSDIWLADESQAERVRGELARFIENPGDPRYLAASWQSGQTNSGLRYRRFPFLATLRERAGPVTWIVMLACVLVYIAMSLIGDQTVMVWLAWPFDPVLKFEVWRYFTHIFMHFSLMHILFNLLWWWYLGGAVEKRLGSGKLIVITVISALLSGYVQQKFSGPWFGGLSGVVYALMGYVWLRGERDPQSGIYLQRGLIIFALLWIVAGWFDWFGMSMANGAHIAGLIVGLAMAFVDTLNARKRTLast
1 -80.9004qnz_A mol:protein length:200 Rhomboid protease GlpG  ali model follow..  88  1......................................................................................AALRERAGPVTWVMMIACVVVFIAMQILGDQEVMLWLAWPFDPTLKFEFWRYFTHALMHISLMHILFNLLWWWYLGGAVEKRLGSGKLIVITLISALLSGYVQQKFSGPWFGGLSGVVYALMGYVWLRGERDPQSGIYLQRGLIIFALIWIVAGWFDLFGMSMANGAHIAGLAVGLAMAFVDSLNARKRK 190
2 -80.2004njn_A mol:protein length:211 Rhomboid protease GlpG  ali model follow..  84  3.........................................................................SSSSGLVPRGSHMAALRERAGPVTWVMMIACVVVFIAMQILGDQEVMLWLAWPFDPTLKFEFWRYFTHALMHFSLMHILFNLLWWWYLGGAVEKRLGSGKLIVITLISALLSGYVQQKFSGPWFGGLSGVVYALMGYVWLRGERDPQSGIYLQRGLIIFALIWIVAGWFDLFGMSMANGAHIAGLAVGLAMAFVDSLNARKRK 205
3 -77.3002nr9_A mol:protein length:196 Protein glpG homolog  ali model follow..  36  2......................................................................................ENFLAQQGKITLILTALCVLIYIAQQLGFEDDIMYLMHYPAYEEQDSEVWRYISHTLVHLSNLHILFNLSWFFIFGGMIERTFGSVKLLMLYVVASAITGYVQNYVSGPAFFGLSGVVYAVLGYVFIRDKLNHHLFDLPEGFFTMLLVGIALGFISPLFGVEMGNAAHISGLIVGLIWGFIDSKLRKNSL 191
4 -31.0004hdd_A mol:protein length:79 Rhomboid protease GlpG  ali model follow..  87  1.LMITSFANPRVAQAFVDYMATQGVILTIQQHNQSDVWLADESQAERVRAELARFLENPADPRYLAASWQAGHTENLY...................................................................................................................................................................................................... 77
5 -28.8002mja_A mol:protein length:69 Rhomboid protease GlpG  ali model follow..  90  1MLMITSFANPRVAQAFVDYMATQGVILTIQQHNQSDVWLADESQAERVRAELARFLENPADLE..................................................................................................................................................................................................................... 63
6 -26.8002lep_A mol:protein length:69 Rhomboid protease glpG 1  ali model follow..  93  1MLMITSFANPRVAQAFVDYMATQGVILTIQQHNQSDVWLADESQAERVRAELARFLENPAD....................................................................................................................................................................................................................... 61
7 -18.6002gqc_A mol:protein length:70 Rhomboid Intramembrane Protease  ali model follow..  23  3AVQVLKFPLSVDLAGFVGLLRRLNVPHRVEESGQQVLWVPDERLAEQVRELYRRYPEGDPQATLEAA................................................................................................................................................................................................................. 70
8 -9.6205xtc_V mol:protein length:140 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11  ali model follow..  10  3............................................................................................................................................................................KVFRQYWDIPDGTDCHRKAYSTTSIASVAGLTAAAYRVTLNPPGTFLEGVAKVGQYTFTAAAVGAVFGLTTCISAHVREKPDLGGCAGGLTLGA.......... 102
9 -9.5702hfv_A mol:protein length:97 Hypothetical Protein RPA1041  ali model follow..  11  17LRELLRTNDAVLLSAVGALLDGADIGHLVLDQNMSILVLVHEDDLAGARRLLTDAGLAHELRS..................................................................................................................................................................................................................... 89
10 -9.2006g2j_Y mol:protein length:143 MCG5603  ali model follow..  11  11.................................................................................................................................................................................YHEVPDGTQCHRKTYITTALGGICGIIGSAYSVSLNPADSTLEAVARVGRYTFTAAAIGAMFGLTTCVSAQVREKPDIGGCAGGLTLGA.......... 105
11 -9.0505gup_V mol:protein length:141 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11  ali model follow..  12  17.........................................................................................................................................................................................ECHRKAYASTSIGGATGLIVSAYSIALKPPASFLEGVARTGRYTFTSAAIGAIFGLTSCISAQVREKPDIGGCAGGLTLGA.......... 103
FFAS is supported by the NIH grant R01-GM087218-01
1 4 8 3 4 2   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Ye Y, Godzik A. Flexible structure alignment by chaining aligned fragment pairs allowing twists. Bioinformatics. 2003 Oct;19 Suppl 2:II246-II255.