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Query: [S] COG4625 Uncharacterized protein with a C-terminal OMP (outer membrane protein) domain, from COG1018

Results of FFAS03 search in PDB1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MIRGIARRPRCAVEGDWMSAGFCHVSEGKACPTAEMRGVALGRFLICGATGLSFLTLSLAAVSDAVAETLLWTGPDGAEWFTDAAWGPSHRVPNAGDDAMINTYGPVITIGTNAEVHQLSIGNAPGDGTLVVQGGLQTNSVILGATGGSSGTASFIGANWANDGDVSVGGNGTGSLLLLHGTTASSENIYVGESGTGSGSLKLDNSSTLTVADTVFAGYNSWSSSAAGGSGNVEVLGASSLYSANGVLANDPDTVGTALVSGGGSSWNMSSDLVVGEAGVGTLTITGGGMVISQTTTVIADLNSADGSSVTVSRLGSSLQSDSLVVGNGGAAKLVVEAAATVTSGEAIIGRHSASEATVTGDGSKWTTGDLQVGGDTSDPGGLAGNGTLNVTAGGSVDSTVAHLGVVAGATGSAIVDGKGSVWTVDRNSLEVGVSGAGSLAVTGGGLVDAANIIIGTNTGGNGSVRVSGADSTVKSRSDLNVGLYGNGSMTVEAGGAVKSRDGYVATYGGSTSAVTVTGDGSSWAMTGTFFVGYASGATGNVTVSNGGAIRATGVTLGDLAGASGTMTITGAGSKVTAYVDNGTVNSGSVDVGFQGSGSLSVVNGGSLDAYNLYVGNALGSSGAVLVSGVGSHVSVDGLMVVGNAGNGSVEITGGASLAAPTILIATEAGSTGVLSIGAGSGQTARSAGAVEARAIAFGAGNGSIVFNHSETGYTLSADISGAGRVVAEAGVTTLSGNNSYSGGTTISAGMLKGTAKSFGSGGIVNNAELVVDGGGTLSNAISGTGSFEKTGDGNLLLTGNSTYSGATAVSAGKLSVNGSLASAVSVGSGATVGGTGTIGGLTVNSGGTLAPGNSIGTLTSTGNATFASGSTYAVEIDADGSSDRLAVTGTITIANDVSLIVTPLGAHSAYSLGTRYTILTATGGVTGTFSSVDESFAYLTAKVAQSGDDATTYLSFLRTSPDSGLLAAATSTANARAAANAVEALGQTSPLYEAALFLQQGETQGAFSQLAGEIHPSLAMALINRSGQSRDVILNRLRSAFEGVDARPILPVAYAEGGQNPFAVDDGALSFWSSGFRSRGRIDSDGNGSSVDMNGGGILFGLDGELSDSWRAGVAAGYGHDGIKQTALAASADVDSYYLAAYAGTQIGPASLRLGAIHAFQDAETRRSISFSTLQESLSASYGGSTSQVFAEAAWRFDFDLTHIEPYANIAYVNTRTDGFQEKGAIAAVSSGSTRYDQLYTTFGARISRDIALEGMLGRAMFDLAWRHNYGDTAMGSSLFYEGGGVFSVASTSSPRDAAILNLGLSYDLTPSATLTFRYGAVFGAGVLDQSAAAELGVRFLast
1 -47.2003kvn_X mol:protein length:632 Esterase estA  ali model follow..  16  9......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................STLVVFGDSLSDAGQFPDPAGPAGSTSRFTNRVGPTYQNGSGEIFGP----------TAPMLLGNQLGIAPGDLAASTSPVNAQQGIADGNNWAVGGYRTDQIYDSITAANGSLIERDNTLLRSRDGYLVDR--ARQGLGADPNALYYITGGGNDFLQGRILNDVQAQQAAGRLVDSVQALQQA-GARYIVVWLLPDLGLTPATFGGPLQPFASQLSGTFNAELTA-QLSQAGANVIPLNIPLLLKEGMAN------ASFGLAADQNLIGTCFSGNGCTMNPTYGINGSTPDPSKLLFDSVHPTITGQRLIADYTYSLLSAPWELTLLPEMAHGTLRAYQDELRSQWQADWENWQNVGQWRGFVGGGGQRLDFDSQDSAASGDGNGYNLTLGGSYRIDEAWRAGVAAGFYRQKLEAGAKDSDYRMNSYMASAFVQYQENRWWADAALTGGYLDYDLKRKFALGGGERSEKGDTNGHLWAFSARLGYDIAQSPWHLSPFVSADYARVEVDGYSEKGASAALDYDDQKRSSKRLGAGLQGKYAF---GSDTQLFAEYAHEREYEDDTQDLTMSLNSGNRFTLEGYTPQDHLNRVSLGFSQKLAPELSLRGGYNWRKGEDDTQQSVSLALSLDF 625
2 -44.3001uyn_X mol:protein length:308 NALP  ali model follow..  15  1..........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................DGVRIFNSLAATVYADSTAAHADMQGRRLKAVSDGLDHN---------------------------GTGLRVIAQTQQDGGTWEQGGVEGKMRGSTQTVGIAAKTGENTTAAATLGMGRSTWS----ENSANAKTDSISLFAGIRHDIGYLKGLFSYGRYKNSISRSTGAD---EHAEGSVNGTLMQLGALGGVNVPFATGDLTVEGGLRYDLLKQDAFAEKGSALGWSGNSLTEGTLVGLAGLKLSQPLSDK---AVLFATAGVERDLNGRDYTVTGGFTGAATGKTGARNMPHTRLVAGLGADVEFGNGWNGLARYSYAGSKQYGNHSGRVGVGYRF 308
3 -20.5003slj_A mol:protein length:313 Serine protease espP  ali model follow..  15  11........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................TRNAAALFSVDYKAFLNEVANLNKRMGDLRDI------------------NGEAGAWARIMSGTGSASG-----GFSDNYTHVQVGVDKKHGLDLFTGFTVTHTDSSASADV--FSGKTKSVGAGLYAS---SGAYIDLIGKYVHHDNEYT-----ATFAGLGTRDYSTHSWYAGAEAGYRYHVTDAWIEPQAELVYGSVSGKQFAWKDQGMHLSMKDKDYNPLIGRTGVDVGKSFSGKDWKVTARAGLGYQFDLLA-NGETVLRDASGEKRI---KGEKDSRMLMSVGLNAEIRDNVRFGLEFEKSAFGKNVDNAVNANFRYSF 307
4 -20.2002qom_A mol:protein length:285 Serine protease espP  ali model follow..  13  13..........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................NGEAGAWARIMSGTGSASG-----GFSDNYTHVQVGVDKKHGLDLFTGFTVTHTDSSASADV--FSGKTKSVGAGLYASAMFDS-GAYIDLIGKYVHHDNEYTATF---AGLGTRDYSTHSWYAGAEAGYRYHVTE--IEPQAELVYGSVSGKQFAWKDQGMHLSMKDKDYNPLIGRTGVDVGKSFSGKDWKVTARAGLGYQFD-----------LLANGETVLRDAGEKDSRMLMSVGLNAEIRDNVRFGLEFEKSAFGKNVDNAVNANFRYSF 277
5 -19.2003qq2_A mol:protein length:284 BrkA autotransporter  ali model follow..  18  17.........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................RADAGGPWARTFSERQQIS-NRHARAYDQTVSGLEIGLDRGWGGRWYAGGLLGYTYADRTYP-GDGGGKVKGLHVGGYAA--VGDGGYYLDTVLRLGRYDQQYNIAGTD-GGRVTADYRTSGAAWSLEGGRRFELPN--AEPQAEVMLWRTSGKRYRASNG---LRVKVDANTATLGRLGLRFGRRIALAGNIVQPYARLGWTQE-----------FKSTGDVRTNGIGHAGAGR-LGAGVDAALGKGHNLYASYEYAAGDRINIPSFHAGYRYSF 284
6 -18.4003aeh_A mol:protein length:308 Hemoglobin-binding protease hbp autotransporter  ali model follow..  13  1....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................GTMQGKAAATFMHISYNNFITEVDNLNKRMGDLRDI------------------NGEAGTWVRLLNGSGSADG-----GFTDHYTLLQMGADRKHSMDLFTGVMATYTDTDASADL--YSGKTKSWGGGFYAS--LFRSGAYFDVIAKYIHNENKYDLN----AGAGKQNFRSHSLYAGAEVGYRYHLTD--VEPQAELVWGRLQGQTFNWNDSGMDVSMRRNSVNPLVGRTGVVSGKTFSGKDWSLTARAGLHYEFD-----------LTDSADVHLKDAGRKDSRMLYGVGLNARFGDNTRLGLEVERSAFGKNTDDAINANIRYSF 306
7 -15.1004mee_A mol:protein length:469 Diffuse adherence adhesin  ali model follow..  13  1................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................SRRSPEYFKGPPSPRSLNPTKESAGTLTVSNYTG-TPGSVISLGGGDNSLTDRLVVKGNTS--GQSDIVYVNEDGSGGQTR-DGINIISVEGNSDAEF------------------------------------------SLKNRVVAGA----------YDYTLQKGNESLTSHLPTSDTRQYRPENGSYATNMTLANSLFLMDLNERKQFRA---------------SDNTQPESASVWMRITGGRSSGKLNDGQNKTTTNQFINQLGGDIY-LGDFTLGIMGGYANAKGKTINYAARNTLDGYSVGVYG---------------TWYQNGENATMQYNWFNASVKGDYNLNGLTASAGGGYNLNVHEFWLQPHLQAVWMGVTPDTHQEDNGTVV---QGAGKNNIQTKAGIRASWKVK-TGREFSPYIEANWIHNTHE------------FGVKMSDDSQSRNQGEIKTGIEGVITQNLSVNGGVAYQAGHGSNAISGALGIKYSF 463
8 -10.9006cgr_n mol:protein length:3139 Large tegument protein deneddylase  ali model follow..  15  937......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................DAALGQQLDSDAAFVPAPGASPYPDDGGLSPEATRMAEEALRQARAMDAAKLTAE-AMLEGA-KLQGVLRPLPDFVGLKACPAVLATLRASLPAGWSDLPEAVRGAPPEVTAALRADMGLLGQYRDALEHPTPDTATALSGLHPSFVV--VLKNLFADAPETPFLLQFFADHAPIIAHAVSNAINAGSAAVATADPASTVDARVLVDAVTALGAAASDPASPLAFLAAMA----DSAAGYVKAT-ARVAIAQLTTLGSAAADLVVQVRRAANQPEGEHASLIQAATRATTGARESLAGHEGRFG--GLLHAEGTAGDHSPSG-GKVIGAEAATADRWAADVEAVLDRVEVELRRLQALAGTHGYNPALGTNAKAVTLALETALAFNPYTPENQRHPMLPPLA---SAAFGA-AADTYADM-------RVDTEPLARLQYVPFFQKGYAE-GSAAAEEISAVRNDPAAAAELVRAGVTLPCPSEDALVACVAALERV--DQSPVKDTAYADYVAFVTQDLADTKDAVVRAKQQRAEATERVTAGLR---VLAARERRAQLEAE..... 1631
9 -10.1005zz8_t mol:protein length:3122 UL36  ali model follow..  15  932......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................DAALAQQLDSDAAFVPATGPAPYVDGGGLSPEATRMAEDALRQARAMEAAKMTAELAPEARS-KLQGVLRPLPDFVGLKACPAVLATLRASLPAGWTDLADAVRGPPPEVTAALRADLGLLGQYREALEHPTPDTATALAGLHPAFVV--VLKTLFADAPETPVLVQFFSDHAPTIAKAVSNAINAGSAAVATASPAATVDAAALADAVSALGAAARDPASPLSFLAALA----DSAAGYVKAT-ARGAIDELTTLGSAAADLVVQARRACAQPEGDHAALIDAAARATTAARESLAGHEAGFG--GLLHAEGTAGDHSPSG-GKVIGAEAAVADRWAAGVEAALDRVEVELRRLQALAGTHGYNPALAANAEAVTLALDTAFAFNPYTPENQRHPMLPPLA---SAAFHA-AAETYADM-------RVDAEPLARLRYVPFFQHGYAD-GGAAAEQISAARNDPEATAELVRTGVTLPCPSEDALVACAAALERV--DQSPVKNTAYAEYVAFVTQDTAETKDAVVRAKQQRAEATERVMAGLR---ALAARERRAQIEAE..... 1626
10 -9.6805nug_A mol:protein length:4646 Cytoplasmic dynein 1 heavy chain 1  ali model follow..  9 1551..................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................FTGSADIKHLLPVETQR---------SISTEFLALMKKVSKSPLVM-------VLNIQGVQRSLERLADLLGKIQKALGEYLERERSSFPRFYFVGDEDLLEIIGNSKNVAKLQKHFKKMFAG---VSSIILNEDNSVVLGISSREGEEHPKINEWLTLVEKEMRVTLAKLLAESVTEV-----------EIFGKATSIDPNTYITWIDKYQAW--------SENVETALSSMGGGGDAAPLHSVTLNVLADSVLMEQPPLRRRKLEHL--ITELVHQRDVTRSLKIDNAKSFEW-----LSQMRFYFDPKQTDVLQQLSIQMANAKFNYGFEYDKLVQTPLTDRCYLTMTQALEARLGGSPAGTGKTESVKALGHQLGFNCDETFDFQAMGRIFVGQVGW----G--------CF---DEFNMLSA-VSQQVQCIQEALREHSNP-----NYDKTS.................. 1994
11 -9.5902dfs_A mol:protein length:1080 Myosin-5A  ali model follow..  11  101...........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................TYCGIVLVAINPYEQLPIYGEDIINAYSGQNMGDMD---IFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYF-ATVSGSASEANVEEKVLASNPIMESIGNAKTTRNDNS-----SRFGK---------------IEIGFDKIIG---ANMRTYLLEKSRVVFQAEEERNYHIF--------QLCASAALPEFKTLRLGNANYFHYTKQGGSPVIDGIDDAKEMVNTRQACLLGISDSYQMG--LAGILHLGNVEFASRDSDSCAIPPKHDPLTIFCDLMGVDYEEMAHWLCHRKLATATETYIKPISLHAINARDALAKHIYANLNWIVDHVNKALHSFIGVGFETFEINSFEQ-----CINYANEKLQQQFNMHVFKLEQE---------MKEQIPWTLIFYDNQPCINLIEAKMGVLDL--MPKGSDDTWAQKLYNTHLNKCALFKVEYQCEFLEKNKDTVYEEQIKV.. 579
12 -9.5204o9y_A mol:protein length:2516 TcdA1  ali model follow..  11  815..............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................GEKASSVLAAFEANSLADAMNLDANLLLQASIQAQNHQHLPPVTPENAFSCWTSINTILQWVNVAQQLNVAPQGVSALVGLDYIQSMKETPTYAQWENAAGV------------------LTAGLNSQQANTLHAFLDESRSAALSTDNQVSAAIKTTRIAEAIASIQLYVNRALENVEENANSGVISRQFFIDWNKRYSTW--------AGVSQ----------------------LVYYPENYID--------------------------TMRIG-----------QTKMMDALLQSVQSQLNADTVEAF--MSY------TSFEQVANLKVISAYHDNINNDQGLTYFIGLSETDAGEY-----RSVDHSKFNDGKFAANAWSEWHKIDCPINPYKSTVIYKSRLYLL----LEQKEITKQTGNSKDGYQTEELKLAHDGTWNT............... 1211
13 -9.5101i84_S mol:protein length:1184 SMOOTH MUSCLE MYOSIN HEAVY CHAIN  ali model follow..  10  45........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................AASIKEEKGDEVTVELQENGKKVTLS---KDDIQKMNPPKFSKVEDMAELTCLNEASVLHNFSGLIYTYSGLFCVVINPYKQLPIYSEKIIDMYKGKKRHEMP---IYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYL-AVVASSHKGKKDTSITQGPSFSYGELEKQLLQAN------ILEAFGNAKTVKNDNSSRFGKFIRINFDVIVG---ANIETYLLEKSRAIRQAKDERFYYLIAGASEQMRNDLLLEGFNNYTFLSNGH-------------PIPAQQDDEMFQETLEAMIMGFTEEEQTS--VSSVLQLGNIVFKKERNTDQASMPDNTAAQKVCHLMGINVTDFTRSILTPRIKVGRDVVQKAQTEQADFAIEALAKAKFERVNKALDKTKRQGASFLGIGFEIFEINSFEQ-----CINYTNEKLQQLFN------HTMFILEQEEYQREG-IEWNFIFGDLQPCIELIERPTNPPGV--LALLDEECWFPKATDTSFVEKTEFCILYAGKVTYNASA........... 595
14 -9.5005z56_2 mol:protein length:895 Splicing factor 3B subunit 2  ali model follow..  10  528........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................IKRTGIQEMREALQEKEEQKTMKSKMREKVRPKMGK-QKLHDAFFKWQTKPKLTIH----GDLYYEGKEFETRLKEKKPGDLSDELRISLG---------MPVGPNAHKVPPP-------WMQRYGSYPNLK---------------IPGLNSPIPE----SCSFGYHAGGW------GKPPVDETGKPLYGD--FGTNAAEFQTKTEWGELEPSDEESSEEEEEEESDEDKPDETGFITPADSGLITPGGFSSVPAGME-IELRKKKIEEA-------MDGSETPQLFTVLPEK--------RTATVGGAMMGSTHIYTVMSRKGPAPELQGVEVALAPEELELDPMAMTQKYEEHVREQQA---DFSDMVAEHAAKQKQKKR-EFKF 895
15 -9.4606ces_D mol:protein length:1603 GATOR complex protein DEPDC5  ali model follow..  9  15................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................GFGGSDDELVV-------NPKVFPHI-------KLGDIVEIAHPNDEYSPLLLQVKSLKEDLQKETIS--VDQTVTQVFLRPYQDVKDVTLDLVELTFKDQ----------------------GRGDMW--------KKSLVSTCAYITQKV--EFAGIRAQAGELWVKNVMCGYISEDTRVVFRSTSAM---VYIFIQMSCEMWDFD-IYGDLYKWKEKNCSHEVTVVLFS---RTFYDAKSVDEFPEI-YKVVVQNERREEWTSLVTIKKLFIQYPVL--STSAQGN-EAINLSFNVFDKHINRNFDRTGQMSVV------------ITP-------GVGVFEVD-MILTKQR-MIDNGIGVDL---VCMGFKLHNR-SRLGDDYNIPHWINHSF 407
16 -9.2902maf_A mol:protein length:238 Opacity protein opA60  ali model follow..  15  1..................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ASEDGGRGPYVQAD------------LAYAYEHITHDYPEPTAPNRSVHPRVSVGYDFGGWRIAADYARYRKWNNNKYSVNIENVRENQENGTFHAVSSLGLSAIYDFQIND-KFKPYARVAYGHVRHSIDSTKKTIEVTTVPSNAPNGAVTTYNTDPKTQNDYQSNSIR---RVGLG---------------------------------VIAGVGFDITPKLTLDAGYRGRLETRFKTHEASLGVRYRF 238
17 -9.2301jwy_A mol:protein length:1100 Myosin-2 heavy chain,Dynamin-A  ali model follow..  10  53................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................CGEIVSETSDSFTFKTVDGQDRQVKKDDANQRNPIKFDGVEDMSELSYLNEPAVFHNLRVR--------NQDLIYTYSGLFLVAVNPFKRIPIYTQEMVDIFKGRRRNEVA---IFAISDVAYRSMLDDRQNQSLLITGESGAGKTENTKKVIQYLASVAGRNQANGSGVLEQQILQANPIAFGNAKTTRNNNSSR------------FGKFIEIQFNSA----GFISG---ASIQSYLLEKSRVVFQSETERNYHIF--------QLLAGATAEEKKALHLAGPESFNYLNQSGCVDIKGVSDSEEFKITRQAMIVGFSQEEQMS--IAGILHLGNIKFEKGAGEGAVLKDKTALNAAST-----FGVNPSVALMEPRILAGRDLVAQHLNEKSSSSRDALVKALYGRLLWLVKKINNVLCQFIGVGFEIFKVNSFEQ-----CINYTNEKLQQFFN------HHMFKLEQEEYLKEK-INWTFIFGDSQATIDL-IDGRQPPGI--LALLDEQSVFPNATDNTLITKTEFGVTYAGQVMYEIQD........... 587
18 -9.0602f1c_X mol:protein length:286 Outer membrane protein G  ali model follow..  9  43................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................WRIALAYYQEVDYSAGKRGTWFDRPELEVHYQFLENDDFSFGLTGGFRNYGYHYVDEKDTANMQRWKIAPDWDVKLTDLRFNGWLSMYKFANDLNTT--------------GYADTRVETETGLQYT-----FNETVALRVNYYLERGFNMDD---------SRNNGEFSTQEIRAYLPLTLGNHSVTPYTRIGLDRWSNWDWQDDIER--------------GHDFNRVGLFYGYDFQNGLSVEYAFEWQDHDEGDSDKAGVGVNYSF 280
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Li W, Godzik A. cd-hit: a fast program for clustering and comparing large sets of protein or nucleotide sequences. Bioinformatics. 2006 May 26;