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Query: [S] COG4984 Predicted membrane protein, from COG1018

Results of FFAS03 search in PDB1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MQNTTLFHLSWRKYLTLLFLLLGTGFFASGVITWIAANWDYFSRFEKLYGVQSLFGVSILLSVFFYYYEAKKKQVTSVLPLVFAFLAAVLLGAIFALIGQTYQTGADPWELFAIWSICQIPFLLLFPNVASALLLLVTANVALSLAISLLGDIVHMTIFLNMLFLVCYEYFGERLRDQNWRILPKIALFILVFAFGWALIVNNSVLLSWLLSAGLVYYYKERRFDFLNLIVLFFYLVVSICTKVLLSSGEDFLSDIFLVTILAFGGTIGAIITLIKWFKWHNPTASRVTWHIYPLFILLIIFCTGLLLITLFFSFGLEDEQDLIYPSILFLIIALVMHFNQKEKADWFDIAIDMFMATGFILYFIFFLFDGENDLYLALMAILSVFLYQLRSSNWLRFLIASLFIIAFLVYIGFFDLRWYAYYEEHLGQFVLSAQQWIILGGLLLYYFFSLSEERPYTIKLLPIAWAMLLVGLAMNLDIFNRWTFLDTAQQTPEMSDLNDWFHVITGYFFTALTSDTWLIKSLHLLISITPIIFFVLISRRFELTKFLYASVLLTLLALCLGFIAVNETLACISLLLLAYLSVSRVLFALALLGVIMNLSYYYYLLSIPLLHKSFLLMGVGIVLALVTFVLLRYNKAPQATLQAESHNTFQPQLast
1 -8.6905mke_A mol:protein length:968 Polycystin-2  ali model follow..  13  208......................................................................................................................................................................................................................................................................................ESSTNREKYLKSVLRELVTYLL-----FLIVLCILTYGMMSSNVYYYTRMMLFLDTPVSKTEKTNFKTLSSMEDFWKFTEGSLLDGLY-SFIFYENLLLGVPRITAAQVASLKKNVWLDRGTRATFI--FSVYNANINLFCVVRLLVEFPAFFLAACEIIFCFFIFYYVVEEILEIRIHKLHYFRSFWNCLDVVIVVLSVVAIGINIYRTSNVEVLLQFLEDQNTFPNFEHLAYWQIQFNNIAAVTVFFVWIKLFKFINFNRTMSQLSTTMSRCAKDLFGFAIMFF----------IIFLAYAQLAYLVFGTQVDDFSTFQECIFTQFRIPIYFTTFVFFMFFILLNMFLAIINDTYSEVKSDLAQQKAE..... 697
2 -8.4106du8_A mol:protein length:805 Polycystic kidney disease 2-like 1 protein  ali model follow..  11  88......................................................................................................................................................................................................................................................................................NTAENRELYIKTTLRELLVYIV-----FLVDICLLTYGMTSSSAYYYTKVMSELFLHTPSDTGVSFQAISSMADFWDFAQGPLLDSLY-SFIYYENMLLGVPRLSAEALRALQEGLWLDRGTRVVFI--FSVYNANINLFCVLRLVVEFPAFFIVGCEVIFCVFIFYYVVEEILELHIHRLRYLSSIWNILDLVVILLSIVAVGFHIFRTLEVNRLMGKLLQ--TYADFEFLAFWQTQYNNMNAVNLFFAWIKIFKYISFNKTMTQLSSTLARCAKDILGFAVMFF----------IVFFAYAQLGYLLFGTQVENFSTFIKCIFTQFRIPAYFVTYVFFVFFVLLNMFLAIINDTYSEVKEELAGQKDE..... 577
3 -7.8706a70_A mol:protein length:577 Polycystin-2  ali model follow..  14  259.................................................................................................................................................................................................................................................................................................................................................................................................QVASLKKNVWLDRGTRATFI--FSVYNANINLFCVVRLLVEFPAFFLAACEIIFCFFIFYYVVEEILEIRIHKLHYFRSFWNCLDVVIVVLSVVAIGINIYRTSNVEVLLQFLEDQNTFPNFEHLAYWQIQFNNIAAVTVFFVWIKLFKFINFNRTMSQLSTTMSRCAKDLFGFAIMFF----------IIFLAYAQLAYLVFGTQVDDFSTFQECIFTQFRIPIYFTTFVFFMFFILLNMFLAIINDTYSEVKSDLAQQKAE..... 551
4 -7.7605kk2_E mol:protein length:323 Voltage-dependent calcium channel gamma-2 subunit  ali model follow..  12  8...............................................................................................................................................................................................................................................................................................................................................................................................................................................VQMLLTTVGAFAAFSLMT---------IAVGTDYWLYSRGVCKTKSVSEN-----ETSKKNEEVMTHSGLWRTCCLEFPEDADYEADTAEYFLRAVRASSIFPIL--------------SVILLFMGGLCIAASEFYKTRHNIILSAGIFFVSAGL--SNIIGIIVYISAYSYGWSFYFGALSFIIAEMVGVLAVHMFIDRHKQLRATARATDYLQASAITR 225
5 -7.5705k47_A mol:protein length:547 Polycystin-2  ali model follow..  14  222.................................................................................................................................................................................................................................................................................................................................................................................................QVASLKKNVWLDRGTRATFI--FSVYNANINLFCVVRLLVEFFDFFLAACEIIFCFFIFYYVVEEILEIRIHKLHYFRSFWNCLDVVIVVLSVVAIGINIYRTSNVEVLLQFLEDQNTFPNFEHLAYWQIQFNNIAAVTVFFVWIKLFKFINFNRTMSQLSTTMSRCAKDLFGFAIMFF----------IIFLAYAQLAYLVFGTQVDDFSTFQECIFTQFRIPIYFTTFVFFMFFILLNMFLAIINDTYSEVKSDLAQQKAE..... 514
6 -7.4403jbr_E mol:protein length:222 Voltage-dependent calcium channel gamma-1 subunit  ali model follow..  14  99..............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................TQKEYSISAAAISVFSLGFLIMGTICALMAFRKKRDYLLRPASMFYVFAGLCLFVSLEVYYYSWSFACACAAFVLLFLGGISLLLFSLPRMPQNPWESCMDA------EPE 221
7 -7.0905z10_A mol:protein length:2547 Piezo-type mechanosensitive ion channel component 1  ali model follow..  10  210.............LVIVLLALAGIAHSAFSSIYLVVF-WSCHFPLSPLGFNTLCVMVSCFGAGHLICL---------YCYQTPFIQDMLPPGNIWALFGLKLPNYSSPNALVLNWPIYVSPGILL-------LLYYTATSLLKLHKSCPSELRKETPREDEEHELELDHLEPEPQARDATQGEMPMTTEPDLDNCTVHVLTSQSPVRQRP--------RPRLAELKEMSPLHGLGHLIMDQSYVCALIAMMVWSIMYHSWLTFVLLLWACLIWTV-------RSRHQLAMLCSPC---ILLYGLTLCCLRYVWAMELPELP-TTLGPVSLHQLGL-----EHTRYPCLDLGAMLLYLLTFWLLLRQFVKETEPTQTQTLLRSLGELVTGIYVKYWIYVCAGMFIVVSFAGRLVVYKIVYMFLFLLCLTLFQVYYTLWRKLLRVFWWLVVA------YTMLVLIAVYTFQFQDFPTYWRNLTGFTDEQLGDGLEQFSVSELFSSILIPGFF--------------LLACILQLHYF-LVADRLLDLAASFSAVLTRIQVFVRRLL-ELHVFKLVALYTVWVALKEVSVMNLLLVVLWA--------FALPYPRFRPMASCLSTVWTCIIIVCKMLYQLKIVNPHEYSSNCTEPF 885
8 -7.0806g1k_A mol:protein length:921 Transient receptor potential cation channel subfamily c member 4a  ali model follow..  10  217...........................................................................................................................................................................................................................................................................FLTAFQLSWELQELSKVENEFKAEYEELSHQCKHFAKDLLLARLKLAIKYRQKEFVAQPNCQQLLASRWYDEFPGWRRRHWAGKLITCVFIGLMFPLLSLCYLVAPKSRYGLFIRKPFIKFICHTASYLTFLFLLLLASQ-----------HIVSNNPDRQGPKPTTVEWMILPWVLGFIWTEIKQMWDGGFQD---WWNFVMNSLYLATISLKIVAYVKYSGCKPRDTWEMWHPTLVAEAVFA-----------IANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIY----------CLVLLAFANGLNQLYF-TLFETLQSLFWSIFGLI-ATMFGTYNVISLVVLLNMLI---------------AMMNNSYQ.. 625
9 -7.0705z1w_A mol:protein length:566 Polycystic kidney disease 2-like 1 protein  ali model follow..  12  221.................................................................................................................................................................................................................................................................................................................................................................................................ALQGLQEGLWLDRGTRVVFI--FSVYNANINLFCILRLVVEFPAFFIVGCEVVFCVFIFYYVVEEILEIHLHRLRYLSSVWNILDLVVILLSIVAVGFHIFRTLEVNRLMGKLLQ--TYADFEFLAFWQTQYNNMNAVNLFFAWIKIFKYISFNKTMTQLSSTLARCAKDILGFAIMFF----------IVFFAYAQLGYLLFGTQVENFSTFVKCIFTQFRIPVYFVTYVFFVFFVLLNMFLAIINDTYSEVKEELAGQKDQ..... 514
10 -6.9306agf_A mol:protein length:1879 Sodium channel protein type 4 subunit alpha  ali model follow..  10 1073..........................................HNWFETFIVFMILLSSGALAFEDIYIEQRRVIRTILEYADKVFTYIFIMEMLLKWVAYGFKV-TNAWCWL------------------FLIVDVSIISLVANWLGYSELGPIKSLRTLRALRPLRALSRFEGMRVVVNALLGAIPSIMNVLLVCLIFWLIFSIMGVNLFAGKFYYCINTTTSERFDISEVNNKSECESLMHTGQVRWLNVKVNYVGLGYLSLLQVATFKGWMDIMYAAVDSREKEEQPQYMYLYFVIFIIFGSFFTLNLFIGVIIDNFNQQITIMILICLNMVTMMVETDNQSQLKVDILYNI---NMIFIIIFTG--------ECVLKMLALRQYYFTVG-W--NIFDFVVVILSIVGLALSDLIQKYFVSPTLFRVIRLARIGRVLRLIIRTLLFALMMSLPALFNIGLLLFLVMFIYSIFGMSNFAYVKKESGIDDMFNFETFGNLFEITTSAGWDGLLNPILNSG------CGNPSIGICFFCSYIIISFLIVVNMYIAIILENFNVATEESSEPLGEDDFEMFYETWEKF-----FIAYSRLSDFVDTLQEPLMVPGDKIHCLDILFALTKEVLGDSGEMD--ALKQTMEEKFM.. 1749
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Ye Y, Godzik A. Multiple flexible structure alignment using partial order graphs. Bioinformatics. 2005 Mar 3;